This month, Deputy Editor Susan K. Schultz, M.D., discusses how psychiatrists can extend their role to treatment of general health conditions, how to evaluate randomized clinical trials, interpersonal psychotherapy for mental health problems, fluidity of symptoms in borderline personality disorder, predictors of bipolar illness in offspring of bipolar parents, and the relation of prenatal maternal distress to fetal behavior and to DNA changes in glucocorticoid-related genes in the placenta. Articles may be viewed online at ajp.psychiatryonline.org.