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c t 3-MCPD i vi sc kho con ngi (!?)

Ni dung chnh: Thc trng v c t 3-MCPD trong nc tng. 3-MCPD l g? 3-MCPD t u ra. Phng php xc nh v ngng an ton. 3-MCPD i vi sc khe con ngi. Bo v c th khi c t 3-MCPD bng cch no. nh hng sn xut nc tng sch trong tng lai.

I. Thc trng v c t 3-MCPD trong nc tng

T lu con ngi bit dng n nc chm trong ba n ca mnh. u nnh ra,luc, (3,4 thng) ph gia nc tng Hin nay, vi s pht trin ca khoa hc ngi ta dng HCL thy phn nguyn liu v ch mt t 1-2 tun nc tng. ng thi ch tiu cht lng v vn sc khe con ngi phi t ln hng u.

 Trong thi gian gn y, d lun ang xn xao v s c mt ca 3-MCPD c trong nc tng. Ngi dn truyn tai nhau rng l cht c, c th gy ung th, v gy cht ngi nu dng nhiu.

II. 3-MCPD l g?

3-MCPD: 3-monochloropropane-1,2diol (C3H7ClO2, 110.5 dvc) Chloropropanols c cc dn xut: 1,3-DCP, 2-MCPD, 2,3-DCP. 3-MCPD c hm lng cao nht tn ti di dng hn hp racemic ca hai ng phn (R) v (S).

1,3-dichloro-2-propanol (1,3-DCP)

2-monochloropropane-1,3-diol (2-MCPD)

3-monochloropropane-1,2-diol (3-MCPD)

2,3-dichloro-2-propanol (2,3-DCP)

III. 3-MCPD t u ra?

Cc nh khoa hc cha tm hiu ht c 3-MCPD sinh ra theo c ch no Cc sn phm: chlorine (NaCl,HCl) + cht bo (chin, nng) 3-MCPD

III.3-MCPD t u ra?
Trong sn xut nc tng quy m cng nghip, dng HCl thy phn nguyn liu Acid Hydrolysed vegetable proteinamin (HPV) 3-MCPD v cc ng phn. tng hng v sn phm, nh sn xut thm Acid HPV ngoi sinh (nc tng, xc xch, kem, bnh quy c 3MCPD).

IV. 3-MCPD c quan tm t khi no?

3-MCPD c bit vo u thp k 80 ca th k 20 (thy phn m thc vt bng HCl). 1991: 3-MCPD c m t, nhng cha c quan tm. 1993: WHO & FAO a 3-MCPD ra bn lun nhn dp Hi ngh v cht ph gia thc phm.

IV. 3-MCPD c quan tm t khi no?

1999: pht hin 3-MCPD trong thc phm nhp t Trung Quc sang Anh (6 124 mg/kg). 11/2001: kim nghim ti vit nam, hm lng 3-MCPD vt qua ngng cho php so vi ch tiu Chu u.

V.Phng php xc nh v ngng an ton ca 3-MCPD.

Phng php xc nh: Tch khi thc phm tc dng vi mt cht trung gian dn xut,tch trn h thng sc k v phn tch bng phng php ph khi. i vi nc tng c th hp th 3-MCPD trn b mt,trch ly bng dithyl eter,c c v phn tch trn h thng GC/MS.

V.Phng php xc nh v ngng an ton ca 3-MCPD.

Ngng an ton: FAO & WHO khuyn co liu ti a c th dung np l 0.002mg/kg Theo tiu chun Vit nam l nh hn 1mg/kg Nhng s liu ny mang tnh cht gi nh a ra cho tt c mi ngi. Ph thuc vo tui , gii tnh, nhy cm ca tng c th
Tn nc M Canada Cc tiu vng quc rp Gii hn cho php(mg/kg th trng) 1 1 1

c
New Zealand Chu u

0.2
0.2 0.2

VI. 3-MCPD i vi sc kho con ngi

Biu hin ca chut vi 3-MCPD: tn thng thn(mn tnh), gim di chuyn ca tinh trng, tn thng thn kinh trung ng Kh nng gy ung th trn chut (Gy t bin gen nu tc ng lp li nhiu ln gy t bin vnh vin gy ung th (carcinogenicity) i vi ngi: gim tc di chuyn ca tinh trng, u ht vim, gim t bo mu, tng nguy c ung th..

VI. 3-MCPD i vi sc kho con ngi

1,3-DCP: gy bin i gen v NST,gan b hoi t,vim ph qun v d dy20 phn t 3-MCPD th c 1 phn t 1,3-DCP. Mercapturic acid: gy hi thn Axit beta-chlorolactic: gim kh nng di chuyn tinh trng. Axit oxalic: gy vim cu thn, tc nghn tuyn thng thn Glycidol: lm bin i gen v NST.

Bo v c th khi c t 3MCPD
Khng dng nc tng qu hn s dng La chn nhng cng ty c uy tn(khng nm trong danh sch en) Khng n qu nhiu cc sn phm chin nng iu kin bo qun tt.

VIII. nh hng sn xut nc tng sch

i vi nh sn xut khng nn dng
cng ngh thu phn bng axit. Gim t l HVP b xung. Dng nhng nguyn liu ti mi. S can thip su hn na ca cc c quan chc nng.