Cng dng ca hot cht chitosan

Tran Van Tuong vantuongtran38@yahoo.com.vn Thuc c hot cht Chitosan Cng dng ca hot cht ny? Thuc ny c th pha chung vi thuc khc c khng?

Tr Li Cu Hi Trn: Trong thi gian gn y chng ta nghe ni rt nhiu v cht chitosan. Cht ny c s dng trong nhiu lnh vc khc nhau trong cuc sng nh: - Trong lnh vc y khoa, nh vo tnh u vit ca Chitosan, cng vi c tnh khng c, hp vi c th, t tiu hu c, nn Chitosan c ng dng rng ri v c hiu qu trong k ngh bo ch dc phm, lm thuc cha bng, gim au, thuc h cholesterol, thuc cha bnh d dy, chng ng t mu, tng sc khng, cha xng khp v chng c c bnh ung th...Theo mt s nh khoa hc th Chitosan c kh nng khng ch s gia tng ca t bo ung th. - Bo qun cc loi thc phm ti sng, ng lnh khi bao gi chng bng cc mng mng d phn hy sinh hc v thn thin mi trng. (theo www.cyberchemvn.com). - Ngoi ra chitosan ng dng trong nhiu lnh vc khc na. Trong nng nghip Chitosan (oligo-chitosa) c s lm thuc bo v thc vt. Theo K S Nguyn Mnh Chinh "Chitosan (cn gi l oligo - sacarit). Chitosan l mt cht hu c cao phn t c iu ch t v tm, cua v mt s loi rong bin. Ngoi tc dng kch thch hot ng ca h thng khng bnh trong cy, Chitosan cn c tc dng nh mt cht kch thch sinh trng ca cy v trc tip tiu dit vi sinh vt gy bnh do hy hoi mng t bo vi sinh vt. Vi cc tc dng trn, Chitosan phng tr c cc bnh cy do cc nhm vi sinh vt nh nm, vi khun, tuyn trng v c virt. C th coi Chitosan nh mt loi vc-xin thc vt. cht Chitosan phng tr nhiu loi bnh quan trng cho nhiu loi cy trng nh bnh o n hi la, bnh thn th hi t, bnh g st hi ch. c bit i vi bnh cht nhanh h tiu, nhiu b con trng h tiu Bnh Phc, k Nng, k Lk s dng v nh gi tt". Theo danh mc bo v thc vt Vit Nam hin nay c khong 20 sn phm ng k. trong c dng hn hp vi hot cht khc (bm vo y xem danh mc). Thuc c th pha chung vi thuc tr su, bnh khc, ch pha Chitosan trc vi nc quy u ri mi a cc cht khc vo.

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cty sn xut chitosan

knh gi: Qu khch hng Cng ty TNHH Hng Tin chuyn sn xut chitin v chitosan t v tm, cua gh... Qu khch hng c nhu cu s dng chitosan hy lin h vi chng ti theo dt: 0979660889 A.Tun , CTY TNHH Hng Tin , l 45A khu cng nghip Tr Nc, Qun Bnh Thy ,TP Cn Th http://www.chitinhungtien.cn

Nghin cu ng dng vt liu chitosan trong y sinh v mi trng

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Chitosan/chitin l mt polisacarit mch thng, c ngun gc t nhin, tp trung nhiu trong v cc loi thy sn gip xc nh tm, cua, mai mc. N c kh nng ha hp v t phn hy sinh hc, c tnh thp, hot tnh sinh hc cao v a dng nh khng khun, khng nm, tng sinh t bo, tng cng min dch ca c th vi cc tc dng kch thch sn sinh bch cu, gim cholesterol trong mu, hn ch s pht trin ca khi u, c tc dng tt trn cc vt thng, vt bng. Trn th gii, vic ng dng chitosan trong cc lnh vc y sinh v x l mi trng c pht trin mnh m. Ti Vit nam, Phng Polyme thin nhin, Vin Ha hc, Vin KHCN VN l mt trong nhng c s u tin nghin cu ng dng thnh cng chitosan trong cc lnh vc ny. Theo hng nghin cu chung , trn c s c th v chuyn mn l nghin cu c trng v ng dng vt liu nano, nhm nghin cu ti Phng Vt liu Nano Y sinh, Vin Khoa hc Vt liu, Vin KHCN VN phi hp vi Phng Cng ngh cc cht c hot tnh sinh hc, Vin Ha hc tin hnh nghin cu ng dng ca chitosan cu trc nano trong y sinh hc (ch to h dn thuc, gm y sinh) v x l mi trng (khng khun, hp ph kim loi nng). ng dng trong ch to gm y sinh Trong nhng nm gn y, cc tin b v vt liu gm y sinh c ng dng v pht trin rt nhiu trong vn chm sc sc khe con ngi. Trong , gm y sinh Hap c nhiu tim nng ng dng do tnh tng thch v hot tnh sinh hc cao, c bit l nhu cu s dng Hap to cc sn phm xng dng trong phu thut chn thng chnh hnh. Vt liu nano HAp/CS c tng hp t dung dch theo phng php phn ng ha hc gia mui cha ion canxi (Ca 2+) vi mui cha gc pht pht (PO43-) c pha trn chitosan.

Cu trc mng Hap/CS trong dung dch m phng SBF (sau 14 ngy)

kim tra hot tnh sinh hc, compozit HAp/CS c ngm trong mi trng gi dch ngi SBF (Simulated Body Fluid) trong khong thi gian 14 ngy v s dng bnh iu nhit gi nhit ca hn hp 37oC. T nh FESEM, ta thy sau 14 ngy cc tinh th HAp bao ph ton b b mt compozit HAp/CS. Kt qu th nghim ny chng t compozit HAp/CS c hot tnh sinh hc tt trong mi trng m phng dch ngi SBF. ng dng trong h dn thuc Chitosan cu trc nano, vi tnh nng quan trng l tng thch sinh hc v c kh nng phn hy sinh hc, c th c s dng nh mt cht dn thuc tim nng. to cu trc ph hp vi mc ch dn thuc cho chitosan, cc tc gi s dng tripolyphosphate (TPP) lm cht to lin kt cho thng qua tng tc tnh in. Qua phn tch sc k lng hiu nng cao (HPLC), qu trnh nh chm c ghi nhn khi thc hin th nghim trong mi trng gi dch rut v gi dch d dy. T thi gian nh thuc khi khng c CS-TPP vo khong 7-8 gi trong mi trng gi dch rut v khong 0,5 gi trong mi trng gi dch d dy, artesunate c ko di thi gian nh thuc ln khong 25-30 gi. Trn c s , CS-TPP c ng dng lm cht dn thuc cho thuc tr st rt artesunate thuc dn xut artemisinin. Bn cnh ng dng lm cht dn thuc cho thuc tr st rt artesunate, nhm nghin cu hin ang tip tc th nghim ch to cc h dn thuc khc, trong c cc h

dn thuc thng minh, v d h dn thuc cha ung th c kh nng hng ch c thnh phn dn dt, thm nhp ni bo v gy cht t bo ung th theo chng trnh hoc h dn c li t tnh, c kh nng c dn dt bng t trng ngoi. Cc h dn thuc ny c cho l s tit kim c dc cht v lm tng ng k hiu qu cha tr bnh. Ngoi ra, vic ng dng cc dn xut khc ca chitosan hay thay th chitosan bng cc polisacarit khc hiu qu hn cho tng ng dng cng ang c tin hnh. ng dng trong liu php nhit tr ung th Nhit tr l mt liu php tr bnh kh ph bin, trong c iu tr bnh ung th. Vt liu ht t c bit n l cht c th lm mi trng sinh nhit (t t nng) di tc dng ca t trng xoay chiu vi yu cu ng dng y sinh l phi bn lu v c thng s tc t ring ban u SRA (Specific Adsorption Rate) phi t cao. Mt s kt qu ban u khi s dng O cacboxymethyl chitosan lm cht bc ht st t Fe 3O4 nghin cu kh nng t nhit cng th hin kh nng ng dng ht nano chitosan bin tnh trong vic nhit tr iu tr ung th. Kt qu t nhit ban u ca mu cht lng cha ht t Fe3O4bc bi O cacboxymethyl chitosan tin hnh cng t trng 80 Oe v tn s 236 kHz c th hin ti hnh sau.

H t t v kt qu t nhit t ca ht t CS/Fe3O4

T th ta thy vi nng ban u ca Fe 3O4l 0.1 mg/ml, kt qu tc gia nhit v nhit bo ha cng thay i tuyn tnh theo cc s pha long khc nhau. Nhng kt qu t nhit ban u nh trn cho thy kh nng ng dng cht lng t trn c s CS/Fe3O4 trong vic t nhit iu tr ung th. ng dng trong hp ph kim loi nng trong dung dch Nhm nghin cu tng hp c nanocomposit Fe3O4/CS v Al(OH)3/Fe3O4/CS vi dung lng hp ph cao, nhm mc ch hp ph ion kim loi nng trong nc, s dng kh nng hp ph tt cc ion kim loi ca CS (nh kh nng tp phc ca cc nhm amino (-NH2)). Vai tr ca Fe3O4l to t tnh cho vt liu m bo vt liu sau

hp ph c tch loi d dng bng t trng, ng thi m ra kh nng gii hp ph (cng bng t trng) v ti s dng vt liu. Kt qu phn tch bng EDS chng minh rng Ni (II), Pb(II), Cu (II), Cr (VI)... c hp ph hiu qu vo b mt mng Fe3O4/CS v Al(OH)3/Fe3O4/CS. ng thi, vi gi thnh hp l, kh nng ng dng vt liu chitosan hp ph kim loi nng, lm sch nc v mi trng l kh thi. ng dng trong ch to dung dch/gel khng khun Chitosan/nano bc (CS/Ag-NPs) c nghin cu ng dng trong vic khng khun trong dung dch nh c tnh khng khun c bit ca ht nano bc. Cc tnh cht ca CS/Ag-NPs c kho st bng ph UV-vis, nh hin vi truyn qua (TEM). Kh nng khng khun ca vt liu trn c kho st vi mt s vi khun nh vi khun gram m (E.Coli v P.aeruginosa), vi khun gram dng (L.fermentum, S.aureus v B.subtilis) v nm (C.albians). Kho st chng minh kh nng ng dng ca vt liu CS/Ag-NPs trong khng khun dung dch. y chnh l c s nhm nghin cu hin ang tip tc tin hnh ch to gel/keo vi ba thnh phn chnh cha nano Ag kt hp vi curcumin, trn nn chitosan nhm a ra sn phm hon ho hn trong y dc v m phm (iu tr cc vt thng ngoi da, c tnh st khun va nhanh lm lin so, lm mn da...) Cc kt qu nghin cu trn c cng b trong 05 bi bo trn cc tp ch quc t (SCI) c uy tn ca Nh xut bn Elsevier (Colloids and Surfaces A: Physicochemical and Engineering Aspects, Materials Science and Engineering:C v Talanta), 02 bi trn tp ch SCI-E (J.Chitin and Chitosan). Cc kt qu ny s b th hin r vt liu chitosan c rt nhiu tim nng ng dng trong y sinh hc v x l mi trng. Ngun: Phng Vt liu Nano y sinh Vin Khoa hc Vt liu X l tin: Bch Dip

DOWICIL 75 Antimicrobial is effective over a wide pH range, and provides broad protection against bacteria and fungi including yeasts. DOWICIL 150 Antimicrobial is a high concentration, free flowing powder, readily dispersible and highly water-soluble formulation of the cis isomer of 1-(3-chloroallyl)3,5,7-triaza-1-azoniaadamantane.