Trng i hc Khoa hc T nhin Khoa Ha hc- Bm Ha phn tch

BI GING CC PHNG PHP PHN TCH CNG C

PGS.TS. T TH THO Email: thaott73@gmail.com

Khi nim v Ha phn tch

Ha phn tch l ngnh ha hc nghin cu v thnh phn cu to (nh tnh) v hm lng cc hp phn (nh lng) trong nhng mu kho st (nh ngha c). Ha phn tch l khoa hc v cc php o trong Ha hc ( nh ngha mi) Ha phn tch ng vai tr quan trng trong khoa hc, k thut, trong nghin cu khoa hc; iu tra c bn pht trin tim nng, khai thc ti nguyn khong sn; nh gi cht lng sn phm Ha hc phn tch l ngnh khoa hc ng dng tng hp cc thnh tu ca cc ngnh khoa hc khc c lin quan nh: ha hc, vt l, ton hc - tin hc, sinh hc - mi trng, v tr, hi dng hc, a cht, a l.v.v...y l mt ngnh khoa hc c s tch hp cao ca nhiu ngnh khoa hc t nhin m mc ch cui cng ca n l em li li ch ti a cho khoa hc, i sng v s pht trin ca con ngi.

WHY TO STUDY ANAL. CHEM.

Environmental Food Agriculture

Medicine

Tocicology

Pharmarcy Analytical chemistry Chemical industry

Criminology

Energetics

Space industry History Law

Geology

Others

Phn tch nh tnh

Phn tch nh lng

Phn tch ha hc

Phn tch cng c

Cc loi phng php phn tch cng c

Signal
Emission of radiation

Instrumental Methods

Emission spectroscopy (X-ray, UV, visible, electron, Auger); fluorescence, phosphorescence, and luminescence (X-ray, UV, and visible) Absorption of radiation Spectrophotometry and photometry (X-ray, UV, visible, IR); photoacoustic spectroscopy; nuclear magnetic resonance and electron spin resonance spectroscopy

Scattering of radiation

Refraction of radiation Diffraction of radiation Rotation of radiation Electrical potential Electric charge
Electric current Electrical resistance
Mass-to-charge ratio

Turbidimetry;nephelometry; Raman spectroscopy Refractometry; interferometry X-ray and electron diffraction methods
Polarimetry; optical rotatry dispersion;circular dichroism

Potentiometry; chronopotentiometry Coulometry Polarography; amperometry Conductometry

Mass spectrometry

Rate of reaction Thermal properties Radioactivity

Kinetic methods Thermal conductivity and enthalpy methods Activation and isotope dilution methods

So snh cc k thut phn tch

Method
Gravimetry Approx. range ( mol/L) 10-1-10-2
Appro xpreci sion (%) 0.1

Selectivit y

Speed

Cost

Principle uses

Poor- mod.

Slow

Low

Inorg.

Titrimetry
Potentionmetry Electrogravimetry, coulometry Voltammetry Spectrophotometry Fluorometry

10-1-10-4
10-1 -10-6 10-1-10-4

0.1-1
2 0.01-2

Poor- mod.
Good Moderate

Mod.
Fast Slow-mod.

Low
Low Mod.

Inorg., Org.
Inorg. Inorg., org.

10-3

-10-10

2-5 2 2-5 2-10 2-5 2-10

Good
Moderate

Mod. Low- Mod.

Fast- mod.

Inorg., org. Inorg., org. Org. Inorg- Multiele. Org. Multicom. Inorg.,org, enzyme

10-3-10-6 10-6-10-9

Good-mod. Moderate
Moderate

Mod. Mod.- High

Fast

Atomic spectrometry
Chromatography Kinetic methods

10-3
10-3

-10-9
-10-9

Good Good
Fast-Mod.

Mod.-high Mod.
Fast- Mod.

10-2-10-10

Good-Mod.

Ni dung chnh mn hc
Phn 1: CC PHNG PHN TCH QUANG HC - Chng 1: i cng - Chng 2: PP trc quang (ph hp th phn t- UV-VIS) - Chng 3: Ph pht x nguyn t (AES) - Chng 4: Ph hp th nguyn t (AAS)

Phn 2: Cc phng php phn tch in ha

- Chng 5: Cc pp phn tch in th - Chng 6: Cc phng php in phn v in lng - Chng 7: Phng php cc ph v von-ampe th khng i

Phn 3: Cc phng php tch trong ha phn tch

Chng 8. Phng php tch chit lng lng v chit pha rn Chng 9. C s l thuyt chung pp phn tch sc k Chng 10 Phng php phn tch sc k lng Chng 11. Phng php phn tch sc k kh

Hc liu
1. Hc liu bt buc 1. Trn T Hiu , T Vng Nghi, Nguyn Vn Ri, Nguyn Xun Trung. Ha hc phn tch phn II- Cc phng php phn tch cng c - Nh xut bn KHKT , H Ni 2007 2. Hc liu tham kho 1. Phm Lun - Phng php phn tch ph nguyn t -Nh xut bn HQG H Ni 2003 2. Trn T Hiu Phn tch trc quang Ph hp th phn t, Nh xut bn HQG H Ni ,2003 3. Douglas A., Skoog, donald M.West, F.James Holler, Fundamentals of Analytical chemistry , saunders College Publihing, 2002-01-01 4. Douglas A.Skoog, K.James Holler , Stanley R.Crouch. Principles of Instrumental Analysis - Thomson- 2006

Ni dung v phn b chng trnh (3 tn ch)

+ Nghe ging l thuyt: 30 gi + Lm bi tp trn lp: 10 gi (20 tit thc hc trn lp) + T hc: 4 gi + Kim tra gia k 1 gi

Kim tra v nh gi
Kim tra thng xuyn: 20% ( im BT v kim tra 15 pht 3 bi). Kim tra gia k: 20% (sau phn II)- 60 pht.

Thi kt thc: 60% (90 pht)