Tp ch Khoa hc 2008:10

Trng i hc Cn Th

PHN LP ANDROGRAPHOLID V NEOANDROGRAPHOLID T CY XUYN TM LIN (ANDROGRAPHIS PANICULATA NEES)

Hunh Vn Ha 1 , Phng Vn Trung v Nguyn Ngc Hnh 2

ABSTRACT
Two diterpenic lactones, andrographolid (XTL1) and neoandrographolid (XTL2) were isolated from ethanol extracts of the whole plant of Andrographis paniculata Nees from Phu Yen by chromatographic methods. Their structures were eluciated by spectrometric methods including 1H-NMR, 13C-NMR, COSY, DEPT, HSQC, HMBC, MS. Keywords: Andrographis paniculata, Acanthaceae, diterpennoids, andrographolid, neoandrographolid Title: Isolation andrographolid and neoandrographolid from Andrographis paniculata Nees

TM TT
T dch chit etanol ca cy Xuyn tm lin trng ti Ph Yn c lp c hai diterpen lacton l andrographolid (XTL1) v neoandrographolid (XTL2) bng cc phng php sc k. Cu trc c xc nh bng cc phng php ph hin i nh 1 H-NMR, 13C-NMR, COSY, DEPT, HSQC, HMBC, MS. T kha: Xuyn tm lin, r, diterpennoids, andrographolid, neoandrographolid

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Trng i hc Cn Th Vin Cng ngh ha hc Vin Khoa hc & v Cng ngh Vit Nam

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