Cc thut ng, cm t dng trong mt bo co khoa hc

Ph HSQC (hnh ) cho php xc nh cc lin kt trc tip gia proton v cacbon da trn cc tng tc gia tn hiu ca proton v cacbon. - Hai tn hiu ca proton olefin ti H 5,92 v 6,82 ln lt tng tc trc tip vi cc cacbon ti C 133,2 v 155,5. Tng tc HMBC (y l loi ph biu din tng tc xa trong khng gian phn t) Tng tc HSQC (cc tng tc trc tip C-H) cc tng tc COSY gia H-1(H 1,41 v 1,90)/H-2 (H 1,60), H-2 (H 1,60)/H-3 (H 1,20 v 1,40) (biu din cc tng tc xa ca H-H, ch yu l cc proton nh vi cacbon lin k ->cc phn ca phn t c ghp ni vi nhau) tng tc NOESY (cc tng tc xa trong khng gian ca H-H khng k n lin kt, ch tinh n khong cch nht nh trong khng gian, cu trc khng gian ca phn t.) Ph 1H-NMR (Error! Reference source not found.) ca 2 cho thy tn hiu dng singlet ca ba nhm methyl ti... Ph 13C-NMR v DEPT (Error! Reference source not found.) ca 2 cho thy tn hiu ca 20 nguyn t cacbon, bao gm 3 nhm methyl ti C cc d liu NMR ca hp cht 2 tng t nh ca hp cht pacovatinin B [58] ngoi tr s khc bit vng lacton Error! Reference source not found..