TRNG I HC DC H NI B MN DC LIU **************

TIU LUN CH : TNG QUAN DC LIU RAU NG BIN

Ngi thc hin : Nguyn Thu Hng Lp A2K66 MSV:1101244

MC LC
Trang T VN ........................................................................................... I. Tng quan .............................................................................................. 1.1. c im thc vt chi Bacopa ........................................................... 1.1.1. V tr phn loi ....................................................................... 1.1.2. Tm tt c im h Hoa Mm Ch 1.1.3. c im thc vt chi Bacopa ............................................... 4 5 5 5 5 6 6 6 7 13 14 14 16 17 18 18 19

1.2. c im thc vt, phn b ca Rau ng bin............................. 1.2.1. 1.2.2. 1.2.3. Tn h .................................................................................... M t ................................................................................... Phn b sinh thi, thu hi, ch bin .......................................

II. Nghin cu thnh phn ha hc ca cy Rau ng bin ................. 2.1.Thnh phn .......................................................................................... 2.2.Phng php nghin cu.................................................................... III. Tc dng dc l . IV. Tnh v, cng nng............................................................................... V. Cng dng ............................................................................................. VI. Mt s sn phm t Rau ng bin ang c ng dng trn

th trng hin nay ........................................................................... 6.1.Thuc Thuc EFTIHEPHA ............................................................... 6.2.Thc phm chc nng PM Kids Intelligent ..................................... 6.3.Vin nang GACHI. Kt lun Ti liu tham kho .................................................................................... 19 20 21 23 24

T VN

Rau ng bin, cn c gi Rau ng, Sam ng. Tn khoa hc: Bacopa monnieri (L),thuc h Hoa mm ch Scrofulariacea. Rau ng bin c s dng nh mt v thuc t hng nghn nm trc trong y hc Ayurvedic - n v c trong sch thuc n t th k th VI. Tc dng v cng dng ca n c cng nhn trong nhiu cng trnh nghin cu. Rau ng bin hin nay c phn b ri rc khp cc vng nhit i, cn nhit i nh Lo, Srilanka, Trung Quc, n , Thi Lan, Vit Nam cy cng mc nhiu vng. Hin nay rau ng bin c s dng lm thuc v thc phm chc nng c tc dng b no, iu tr chng mt ng v cng thng thn kinh, phng v iu tr bnh l ln cho ngi gi. Rau ng bin c bit thch hpcho hc sinh, sinh vin v nhng ngi lm vic tr c v n tng cng kh nng hc tp, ghi nh, gip tinh thn tnh to v tp trung . gip cc bn hiu hn v loi dc liu tuyt vi ny, ti xin trnh by mt s nt tng quan v rau ng bin.

I. Tng quan 1.1. c im thc vt 1.1.1. V tr phn loi Rau ng bin . Tn gi khc: Rau sam ng, cy rut g, cy ba kch. Tn ting Anh: Water Hyssop, Bacopa. Tn khoa hc: Bacopa monnieri (L.) Wettst. Tn ng ngha: Herpetis monnieri (L.) H.B.K., Gratiola onniera L., Septas repens Lour., Bramia indica Lamk. Phn loi thc vt: H Hoa Mm Ch (Scrophulariaceae); B Hoa Mm Ch (Scrophulariales); phn lp Cc (Asteridae) ;lp Ngc lan(Magnoliopsida), ngnh Ngc Lan( Magnoliophyta), gii thc vt (Plantae). Gii thc vt (Plantae) Ngnh Ngc Lan (Liliopsida) Phn lp Cc (Asteridae) B Hoa Mm Ch (Scrophulariales) H Hoa Mm Ch (Scrophulariaceae) 1.1.2. Tm tt c im h Hoa Mm Ch (Scrophulariaceae) Cy thn c, sng nhiu nm, cy bi, t khi l cy g. L mc so le hay mc i, l nguyn khng c l km. Hoa n c hoc cm hoa xim, bng, chm. Hoa khng u, lng tnh, mu 5, c 5 l i lin nhau, trng hoa thng hnh mt n. B nh 4 nh do c 1 nh lp, b nh 2 tri, c khi ch cn 2 nh. B nhy gm 2 l non. Bu trn, 2 . Qu nang, t khi qu mng, nhiu ht, ni nh nc. Hoa thc: K(5) C(5) A2-4 G(2)

Hoa

1.1.3. c im thc vt chi Bacopa Cy tho mc hng nm hay sng dai, c thn mc b hay mc ng, hnh tr hay hi c 4 cnh. L mc i, khng cung, c mp nguyn hoc ch hi c rng. Hoa n c v nch; l bc con 2, tn ti. i c 5 l i ri n tn gc, c tin khai ng im, l i trn, ln hn, hnh trng hay hnh trng rng, hai l i bn nh hn, hnh ngn gio hay hnh di. Trng hnh ng hay hnh chung, c hai mi, vi 5 thy gn bng nhau. Nh thng 4, t khi 2 hay c 2 ci di hn, tht vo trong, ch nh hnh si; bao phn c 2 song song, dnh nhau. Bu hnh bu dc; vi nhy dng si, c 2 thy bng nhau nh. Qu nang hnh trng hay hnh cu, nm trong i tn ti, m bi 2 van; ht nhiu, nh, vi v c vn mng. 1.2. c im thc vt, phn b ca Rau ng bin 1.2.1. Tn h Tn khoa hc: Bacopa monnieri (L.) Wettst. Tn ng ngha: Herpetis monnieri (L.) H.B.K., Gratiola monniera L., Septas repens Lour., Bramia indica Lamk. H : Hoa mm ch (Scrophulariaceae)

1.2.2. M t

Bacopa monnieri Thn c, mc b di trn mt t, sng lu nm. Thn nhn, mu xanh, thn non i khi c mu hi nu , tit din trn, mng nc, c r mu, phn nhnh nhiu, mc ng. Thn l c v ng. L n, mc i, khng lng, dy, mng nc, c dng hnh mung hay hnh trng ngc, t u, di 2-2,8 cm, rng 0,5-0,7 cm, mp nguyn, khng lng, 2 mt l c nhiu chm lm. L c mu xanh m mt trn, xanh nht mt di, 1 gn chnh, gn ph khng r. Hoa n c, mc nch l, mu trng hay mu tm nht. Hoa khng u, lng tnh mu 5. Cung hoa di 2,6-5,6 cm, khng lng, hai l bc con hnh di, di 0,6 cm, nh cung hoa. Bao hoa: 5 l i ri, khng u, l i sau to nht, hnh trng, c 5 gn chnh, di 0,8 cm, r ng 0,5 cm, 2 l i trc hnh trng, mi nhn, 3 gn chnh, di 0,7 cm, rng 0,4 cm, 2 l i bn nh nht, hnh di, 1 gn, c lng ba, di 0,6 cm, rng 0,1 cm. L i 5, c mu xanh m mp, xanh nht bn trong v c chm lm 2 mt, tin khai nm im. Cnh hoa 5, c lng, mi cnh hoa c 3 gn, dnh nhau bn di to thnh ng di 0,4 cm, y ng mu tm nht hay mu trng, tin khai ng im hay kt lp. Nh 4, khng u, 2 nh di 5 mm pha trc, 2 nh ngn 1 mm pha sau. Nh sau b try khng li du vt. Nh nh gn y ng trng xen k cnh hoa; ch nh nhn, hnh si. Bao phn 2 , ri, xp song song cnh nhau, m dc, hng

trong, nh y. Ht phn ri, mu vng nht, hnh bu dc hay hnh trn c 3 thy, c rnh. L non 2, v tr trc sau, dnh nhau thnh bu trn 2 , mi cha nhiu non, nh non trung tr. Vi nhy 1, nh bu, dng si, nhn, di 5 mm, u nhy hnh chn chia 2 thy, mu xanh nht. Qu nang, hnh trng, kch thc 5 x 3 mm, c mi, ng trong i nhn, vi nhy tn ti. Ht nh, nhiu, hnh tam gic, c cnh. Hoa thc v Hoa :

c im gii phu: Thn Vi phu gn trn. T bo biu b c kch thc khng u nhau, hnh ch nht, cutin mng c rng ca, trn biu b c nhiu l kh v lng tit a bo. Di biu b l m mm xp, hnh a gic hay hnh bu dc, kch thc khng u, sp xp khng th t cha nhng khuyt rt to. Thn gi c nhiu t bo cng th nm bn trong t bo m mm, thn non khng c. Ni b khung caspary r, gm 1 lp t bo hnh ch nht, khng u. Tr b gm 2 lp t bo hnh a gic, xp kht nhau, to thnh vng lin tc. Cc b libe g to thnh vng lin tc, libe ngoi, g trong. Tia ty gm 1-3 di t bo. Libe 1 tp trung thnh tng m. Mch g 2 kch thc khng u nhau. M mm ty gm nhiu t bo hnh bu dc to, khng u, sp xp ln xn cha nhng khuyt nh. Ht tinh bt nhiu trong m mm v, m mm ty v ni b.

Vi phu mt ct ngang ca thn Bacopa monnieri a.B mch b.TB nhu m lin kt c. Tinh th canxi oxalat d. Libe v g

L Chiu dy ca tht l gn bng ca gn gia. Gn gia: biu b cu to bi 1 lp t bo hnh a gic, kch thc khng u, t bo biu b trn c kch thc ln hn t bo ca biu b di. Lp cutin mng, c rng ca. M mm o gm 3-4 lp t bo hnh bu dc di hay hnh a gic. Cc b libe g xp thnh hnh bu dc, libe di, g trn, libe tp trung thnh tng m p trn g. Tia ty hp 1 di t bo. Phin l: Biu b ca tht l cu to tng t nh biu b ca gn gia, trn biu b c nhiu l kh v lng tit a bo, l kh nm thp hn so vi biu b. Lng tit a bo gm 2 dy t bo vch mng, nm tht su hn so vi t bo biu b. Di biu b trn l m mm o, gm 3 lp t bo, lp t bo trn hnh bu dc, 2 lp t bo di hnh bu dc di. Trn biu b di gm nhiu lp t bo m mm hnh a gic, khng u. Tinh bt c nhiu trong m mm,

c bit tp trung rt nhiu 2 mp l. Cc b gn ph b ct ngang c cu to tng t nh b gn gia nhng s lng libe g t hn, mt s t gn ph b ct xo.

Vi phu l Bacopa monnieri a. Kch thc l b. Mt ct ngang gn l c. B mch d. Libe g e. L kh

c im bt dc liu: Bt thn mu vng nu, x nhiu. Thnh phn gm: T bo m cng hnh ch nht, ring l hay tp trung thnh m. T bo cng th nm bn trong t bo m mm hay nm ngoi t bo m mm, vch mng. Mnh biu b vch un ln nhiu, mang l kh kiu hn bo hay lng tit a bo. Mnh t bo m mm hnh bu dc hay hnh ch nht di. Ht tinh bt nhiu, nh, hnh trn, ng knh khong 5m, t khng r. Mnh mch vch, mch xon, mch mng.

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Vi phu bt thn dc liu a. Si b-e. Ht tinh bt c. Tinh th hnh lng tr d. Mnh m mang tinh bt

Bt l mu xanh nu, mn, c mi thm. Thnh phn gm: Mnh biu b ca gn l gm cc t bo hnh a gic xp kht nhau. Mnh biu b vch un ln, mang l kh kiu hn bo hay lng tit a bo. Mnh m mm tht l hnh bu dc di, xp cha nhng khuyt nh. Mnh m mm ca mp l cha rt nhiu ht tinh bt. Mnh mch mng, mch vch, mch xon. Ht tinh bt tp trung thnh m, hnh trn, ng knh khong 3,75 m, t khng r.

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Vi phu bt l dc liu a. tinh th Anicocytic b. L kh c. Si ha g d. Git tinh du e. tinh th lng tr f. Mnh mch

Bt hoa mu nu nht, t x.Thnh phn gm: Mnh biu b trn ca cnh hoa hi un ln. Mnh biu b di cnh hoa vch un ln nhiu, c lng che ch a bo. Mnh m mm hnh bu dc di, cha tinh bt. Mnh biu b l i vch un ln, cha l kh kiu hn bo, lng tit a bo, lng che ch a bo. Ht phn hnh trn hay hnh bu dc, c rnh, ng knh khong 50 m. Mnh mch vch, mch mng, mch xon.

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1.2.3. Phn b sinh thi, thu hi, ch bin 1.2.3.1. Phn b: Bacopa monnieri phn b rng cc vng nhit i v cn nhit i. Cy thng pht trin trong khu vc m ly trn khp n , Nepal , Sri Lanka , Trung Quc , i Loan , Vit Nam , v cng c tm thy Florida , Hawaii v cc tiu bang min Nam khc ca Hoa K, ni n c th c pht trin trong iu kin m vn, ao, m ly. Vit Nam, cy phn b khp cc vng ng bng v trung du min Bc v min Nam. Cy a sng thng mc trn t m, pha ct ln vi cc loi c thp b rung, cc bi c m t vng thp ln ti cao 500 m, bi sng, b knh mng, nc ta gp t Qung Ninh, H Ni, Hi Phng, H Nam, Ninh Bnh, Tha Thin Hu, Qung Nam, Nng, Bnh nh, Khnh Ha, Ninh Thun, Ty Ninh, ng Nai, Thnh ph H Ch Minh, Vnh Long, Cn Th, ng Thp. Cy ra hoa qu nhiu hng nm, ti sinh t nhin ch yu t ht, cy cn c kh nng mc chi khe t k l, k c phn cn st li sau khi ct.

1.2.3.2. Cch trng Cy c kh nng sng trong nc thm ch c th sng nc l. Trng v nhn ging do chi hay thn, r mc t t thn ra. Cy a sng thng mc trn t m, pha ct ln vi cc loi c thp b rung, cc bi c m t vng thp ln ti cao 500 m, bi sng, b knh mng.

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Ma rau ng mc r nht l t thng 3 m lch n thng 11 m lch.Vo nhng ngy ma, rau ng bin ln nhanh nh thi. Chn hi rau ng bin phi cng chnh lc ny cy rau mi no nc v mp mp. Hi rau ng bin ngi ta c cm nguyn nm m ct st chn rau b li r. Cy ra hoa qu nhiu hng nm, ti sinh t nhin ch yu t ht, cy cn c kh nng mc chi khe t k l, k c phn cn st li sau khi ct. 1.2.3.3. Ch bin Thu hi phn trn mt t, ra sch, dng ti hay phi kh.

II.Nghin cu thnh phn ha hc cy Rau ng bin (Bacopa monnieri) 2.1 Thnh phn: Thnh phn ha hc chnh ca bacopa monnieri gm cc triterpen t do, saponin, flavonoid, alkaloid v cc phenylethanoid glycosid. Trong o thnh phn c bit n nhiu nht l cc saponin. Cc saponin trong Rau ng bin c thnh phn chnh l jujubogenin v pseudojujubogenin. Cho ti nay c trn 14 saponin c bit t cy ny. Cc cht ny gm:
OH
OH

O O

RO

RO

Jujubogenin

Pseudojujubogenin

Saponin c sapogenin l jujubogenin: bacosaponin A,bacosid A3, bacopasaponin E, bacosaponin F, bacopasid N1, bacopasid X, bacopasid IV Saponin c sapogenin l pseudojujubogenin: bacosaponin B, bacopasaponin C, bacosid N2, bacopasid I, bacopasid II, bacopasid III, bacopasid V

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HO O H RO O R1 H

O OAc OR2
Rham X= Ara Ara Rham

Bacobitacin A Bacobitacin B Bacobitacin C Bacobitacin D

R=R1=R2=OH R=R1=H R2=OH R=X R1=R2=H R=X R1=OH R2=H

Cc saponin khc nhau ch yu phn ng trn C-3 v C-20. Tt c cc saponin u c mch ng C-3. Mch ng trn C3 c t 1-3 ng. Khi l 3 ng , mch ng c th phn nhn. Ch c 3 bacopasaponin A,E v F C20 c thm 1 mch ng vi 1 ng duy nht l -L-arabinopyranose. Cc nghin cu ban u v chi ny bo co v s hin din ca 2 saponin chnh l bacosid A bacosid B.Cu trc ca bacosid A c xc nh l 3-(-Larabinopyranose)-O--D-glucopyranosid-10,20-dihydroxy-16-keto-dammar-(24)en.Nhiu nghin cu dc l sau cng cng b nhng kt qu th nghim trn 2 saponin ny. Cc nghin cu v ha hc ny tm ra nhiu saponin mi trong Rau ng bin. Nhiu cht l thnh phn hn hp m trc y thng c gi l bacosid A v B. Ngoi cc thnh phn saponin, Rau ng bin cn c cc nhomd hp cht khc bao gm: Cc cucurbitacin l bacobitacin A,B,C v D, cucurbitacin E. Triterpen t do: ebelin lactone, bacogenin A1, A2, A3, jujubogenin, pseudojujubogenin, bacosin, acid betulinic. Cc phytosterol Cc alkaloid l brahmin, mt lng rt nh nicoyin v cc alkaloid khc, Cc dn xut phenyl ethanoid glycosid l monierasid I-III v plantanosid B, 3,4-dihydroxyphenylelthyl alcohol (2-O-feruloy)--D-glucopyranosid v phenylethyl alcohol [5-O-p-hydroxybenzoyl--D-apiofuranosyl-(12)] -Dglucopyranosid

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 Ngoi ra cn c dn cht mastutaka alcohol [(3R)-1-octan-3-yl-(6-Osulfony)--D-gluco-pyranosid] v herpestin. 2.2 Phng php nghin cu kim nghim Saponin 2.2.1. Da trn tnh cht to bt: y l tnh cht c trng nht ca saponin do phn t saponin ln v c cng mt lc mt u a nc v mt u k nc. Ngi ta da trn hin tng gy bt mi trng kim v acid s b phn bit saponin steroid v triterpenoid. C th da vo ch s bt nh gi mt nguyn liu cha saponin: ch s bt l s ml nc ho tan saponin trong 1g nguyn liu cho mt ct bt cao 1cm sau khi lc v c (tin hnh trong iu kin qui nh). 2.2.2. Da trn tnh cht ph huyt: y cng l tnh cht c trng ca saponin. Tuy nhin cng c mt vi saponin khng th hin r tnh cht ny. Kh nng ph huyt cng khc nhau nhiu ty loi saponin. Ngi ta cho rng tnh ph huyt c lin quan n s to phc vi cholesterol v cc ester ca n trong mng hng cu nhng li thy rng gia ch s ph huyt v kh nng to phc vi cholesterol c nhiu trng hp khng t l thun vi nhau nn ngi ta cho rng phi xt n nh hng ca saponin trn cc thnh phn khc ca mng hng cu. Qua vic theo di tnh ph huyt ca saponin ngi ta thy rng cu trc ca phn aglycon c tc dng trc tip n tnh ph huyt nhng phn ng cng c nh hng. Hng cu ca cc ng vt khc nhau cng b tc ng khc nhau i vi mt saponin. Hng cu cu d b ph huyt nn dng tt, c th dng mu ca sc vt c sng khc, hoc dng mu th thng d kim i vi cc phng th nghim. nh gi mt nguyn liu cha saponin, ngi ta da trn ch s ph huyt l s ml dung dch m cn thit ho tan saponin c trong 1g nguyn liu gy ra s ph huyt u tin v hon ton i vi mt th mu chn (tin hnh trong iu kin qui nh). 2.2.3. Da trn c i vi c: C l ng vt rt nhy cm vi saponin nn ngi ta dng cc cy c saponin thuc c (ng nhm vi rotenon). nh gi nguyn liu cha saponin, ngi ta c th da vo ch s c. Ch s c cng phi tin hnh trong nhng iu kin quy nh: mi trng, loi c,... D- Kh nng to phc vi cholesterol: Nhng saponin triterpenoid to phc km hn loi steroid. Trong loi steroid th digitonin kt hp vi cholesterol gn

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nh hon ton, do digitonin c dng lm thuc th nh lng cholesterol trong ho sinh. 2.2.4. Cc phn ng mu: Acid sulfuric m c ha tan cc saponin v cho mu thay i t vng, , l-xanh l hay l-tm (phn ng Salkowski). Phn ng Liebermann-Burchardt cng hay dng phn bit 2 loi sapogenin: ly vi miligram sapogenin ho nng vo 1ml anhydrid acetic, cho thm 1 git H2SO4 m c, nu l dn cht steroid th c mu l-xanh l, cn dn cht triterpenoid th c mu hng n ta. 2.2.5. Sc k lp mng 2.2.6. nh lng: Phng php cn. Chit saponin ri cn. Cch tin hnh chit nh SKLM. Phng php o quang: Phng php ny c th dng nh lng ring bit cc sapogenin sau khi tch bng sc k giy hoc sc k lp mng. 2.2.7. Xc nh bng quang ph: Cc sapogenin triterpenoid trong H2SO4 m c c nh hp thu cc i trong vng t ngoi 310 nm. Cc i ny khng th hin vi cc saponin steroid. Ph hng ngoi ca cc sapogenin steroid c bit c 4 pic c trng ca mch nhnh spiroacetal: pic th nht 850 - 857 cm-1 i vi cc cht 25 S hoc 860 - 866 cm-1 i vi cc cht 25 R. Pic th hai gn 900 (894-905), pic th ba gn 915 (915-923), pic th t gn 980 (980-987). phn bit sapogenin thuc 25 R hoc 25 S th cn c vo cng hp thu ca pic th hai v pic th ba: cc cht 25 R th pic th hai c cng hp th mnh hn pic th ba; i vi 25 S th ngc li. III. Tc dng dc l chut, cao chit ethanol ca Rau ng bin tng lng GABA trong no 15 pht sau khi ung. Chut cng ung cao rau ng trong 24 ngy, tng kh nng hc hi. Cao chit ethanol ca Rau ng lm gin c trn hi trng, c trn kh qun, ng mch ch ca th th nghim c s tham gia ca cc prostaglycin v tc dng i vn calci khng chn lc. Saponin ca cy ny gim hot tnh vn ng chut ln c tc dng lm an thn chut ln nhng khng ngn chn c phn ng phng v c iu kin cng nh bo v chut khi b ng kinh do tc ng m thanh. Mi y, cao

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rau ng ci thin nhiu mu t thi hc hi ca chut (behavioral models of learning). Cc bacosid A v B cho thy tc ng ph thuc vo liu dng. Triterpen t do bacosin c tnh gim au qua h thng opioid. Cc saponin cng lm tan huyt v c tc dng trn giun. Mt s cht trong rau ng bin c tc dng h ng huyt nh trn m hnh streptozocin [J. Nat.Prod.,2002,65(12), 1759-63]. IV. Tnh v, cng nng Rau ng bin c v ng, tnh mt, c tc dng thanh nhit, gii c, li tiu tiu thng, cn dng khai v kch thch, chng co tht, thng hi, tr thn kinh v tr tim. Thng c dng tr: 1. Xch, bch l (l ra mu, m); 2. Mt sng au; 3. Da sng ; 4. Nhc mi t bi, n ng tn thng; 5. Vim gan vng da (thay v rau m); 6. Ho. Dng ngoi da tm tr gh. n , ngi ta dng ton cy tr hen suyn, ng kinh, in r, mt ting v dng thn l tr rn cn. Xri Lanca ton cy dng lm thuc x, v un nc nng ra cha bnh nht c sng ngoi da nh da voi. V. Cng dng 5.1.Rau ng bin c dng lm rau Dng n sng: C th dng ring hoc dng chung vi cc loi rau khc. Tuy nhin do v ng m nn rt t ngi quen n sng. Rau ng bin n vi cho nng rt tt. Rau luc: Rau ng bin tt nht l em luc, cht ng b loi bt do tan vo nc. Rau ng bin luc chm vi tht kho, c kho, tng, chao, mm kho, mm ruc Xo: Rau ng bin c xo vi du, m, nc ct da vt tht, tm, ch, nhi. Nu canh: Rau ng bin c th nu canh vi tht, c, tm, cua, ch, nhi n rt b dng. 5.2. Rau ng bin c dng lm thuc n ,trong y hc c truyn ngi ta coi Rau ng bin l mt dc liu qu, c dng trong rt nhiu bi thuc tr hen suyn, khn ting, ng kinh,

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in r, mt ting, dng thn l tr rn cn v cng c xem nh thuc b thn kinh, tim, thuc li tiu. Xri Lanca ton cy dng lm thuc x, v un nc nng ra cha bnh nht c sng ngoi da nh da voi. Trong y hc c truyn Vit Nam Rau ng bin thng c dng tr: 1. Xch, bch l (l ra mu, m); 2. Mt sng au; 3. Da sng ; 4. Nhc mi t bi, n ng tn thng; 5. Vim gan vng da (thay v rau m); 6. Ho. Dng ngoi da tm tr gh. Rau ng bin thng c dng trong cc trng hp lo u, mt ng, suy gim hay mt tr nh. Khoa hc hin i cn pht hin rau ng bin c tc dng gim au, khng vim, c ch t bo ung th, dng tt cho hi chng rut kch thch, cho bnh nhn Alzheimer, nhng bnh nhn sau khi b t qu 5.3. Tc dng khng mong mun Khuyn co nhng ph n mang thai khng nn dng hay trong th i k cho con b. VI. Mt s sn phm t Rau ng bin ang c ng dng trn th trng hin nay 6.1. Thuc EFTIHEPHA

Thnh phn :cho 1 vin nn Bt Dip h chu ( Herba Phyllanthi urinariae powder)100 mg Bt Actis ( Folium Cynarae powder).............................40 mg

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Bt Rau ng (Bacopa monnieri powder)......................20 mg Cao ru mo ( Herba Orthosiphonis Extractum).............10mg T dc :Colloidal silica anhydrous, Calci carbonat, Nipagin, Ethanol 96%, Magnesi stearat, Natri starch glycolat, Shellac, Gm Arabic, Titan dioxyd, Ponceau 4R, Mu Brown HT, Vng Tartrazin, Gelatin, Bt Talc, ng trng, Nc tinh khit, Sp ong trng, Sp ong nu. Liu dng: Ngi ln: Ung 2 vin/ln, ngy 3 ln. Tr em: liu ngi ln. Ung thuc trc ba n. ng gi:Hp 10 v x10 vin bao ng Tc dng: Lm gim men gan v phc hi chc nng gan. Dng trong vim gan siu vi B mn tnh, mn nht, mn nga. Thng tiu, bi tit cht c c th, gip tiu ha tt. Chng ch nh: Qu mn vi bt k thnh phn no ca thuc. Ph n c thai. Ngi ang c bnh chy mu. 6.2.Thc phm chc nng PM Kids Intelligent

Hot cht Mi mt vin nang c cha

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Acetyl L'Carnitine Du c t nhin(docosahexaenoic acidDHA 15mg)125mg Du c t nhin(C Ng)(docosahexaenoic acidDHA 32.5mg)..125mg Axit Folic50mcg Zinc amino acid chelate(tng ng Zinc 1mg)..5mg Bacopa monnieri (Brahmi tng ng vi kh)...50mg Tc dng: Cho s pht trin v tng trng ca tr: Gip cho h thn kinh pht trin, ci thin tp trung, nhn thc, kh nng hc tp v tr nh, gip duy tr tun hon ngoi bin, cung cp thm cc cht dinh dng . Liu dng: Tr em: 1 vin mt ngy ng gi:60 vin / hp v

6.3.Vin nang GACHI

Thnh phn :cho 1 vin nn Linh chi (Ganoderma Lucidum)......................................... : 2000mg Da cn (Herba Catharanthi rosei).................................... : 2000mg Sn tra (Fructus Mali)........................................................ : 500mg Rau ng bin (Bacopa monnieri)....................................... : 250mg

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Cao l Bch qu (Extractum Ginkgo biloba)........................... : 20mg Tc dng Gip lm gim cholesterol mu, h tr n nh huyt p. Tr gip tiu ho, gii c v tng cng chc nng gan, ci thin tr nh. Gip tng kh nng min dch, phng v h tr iu tr ung th. i tng s dng: Dng cho ngi b bnh tim mch nh: cao huyt p, thiu nng mch vnh. Ngi b m trong mu cao, gan nhim m. Cc trng hp suy gim chc nng gan, thiu nng tun hon no, ngi b ung th sau ha tr, x tr. Liu dng: Ngi ln: Ngy ung 2 ln, mi ln 2 vin Tr em t 12 15 tui: Ngy ung 2 ln, mi ln 1 vin i vi ngi bnh sau x tr, ha tr liu: Ngy 2 ln, ln 3 vin. C th s dng lu di m khng s tc dng ph. ng gi: Chai 30 vin nang.

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KT LUN

Ngy nay th gii c xu hng chung l quay v nghin cu v s dng cc sn phm c ngun gc t nhin iu tr bnh nh s an ton v tc dng a dng. Rau ng bin l mt mt v thuc dn gian vi nhng tc dng phong ph, d trng, d thu hi v ch bin. V vy nghin cu v pht trin loi cy ny trong y dc l hng i y tim nng. Bi tiu lun cung cp nhng thng tin khi qut v Rau ng bin cng nh sn phm ca n. Bi tiu lun vn cn nhiu thiu st,em rt mong qu thy c v cc bn gp hon thin hn!

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TI LIU THAM KHO

Ti liu ting Vit 1. Dc liu hc tp 1 (2011), Trng i hc Dc H Ni. 2. B Y t (2002), Dc in Vit Nam III, Hi ng Dc in Vit Nam. 3. Nhiu tc gi, Cy thuc v ng vt lm thuc Vit Nam II, NXB Khoa hc v k thut H Ni. 4. Phm Hong H , Cy c Vit Nam, NXB Tr. 5. Gii phu hnh thi thc vt, Hong Th Sn (ch bin), NXB GD 1998

Ti liu t Internet 6. http://www.wikipedia.org 7. http://duoclieu.org 8. http://www.botanyvn.com/ 9. http://www.ayujournal.org/

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