Gram

Gram (+)
(+)
Bacteria
Bacteria
Enter
Body
Enter Body

Symptomatic
Antiinflamma
tory
Analgesic

Causative

Changed
by
Changed
by
Antibio
Erythromyc
in

Colonizatio
n
Host
Defense

Cell Injury

Inflammati
Inflammati
on
on

Ibuprofen
Ibuprofen

Ampicillin

Mediators
Mediators
(Cytokines)
(Cytokines)

Sputum
Sputum
Production
Production

Increased
Increased
Leukocyte
Leukocyte

Cough
Cough
Symptomat
ic

TNF-
TNF-

Anorexia

Insomnia

IL-1

Symptomatic
Fever
Antipyr
etic

Paracet
amol
amol

Ambro
Ambro
xol
xol

Stimulate
Stimulate
the
the
production
of
eicosanoids
Increase of
cox-2
Prostagland
in
increased
Hyperalgesi
Hyperalgesi
c
c

Antigen
Antigen
(ampicilin)
bind
bind with
with cell
cell
Production
Production
of IgE
IgE by
by of
cell
cell
IgE bind
with IgE
IgE Fc
Fc
with
receptor
in
receptor in
mast cell
Antigen
bind with
Causative
IgE-armed
Antimast cell
Mast cell
degranulati
on
Histamine
Histamine
production
production
Histamine
bind
with
bind with
H1
receptor
H1 receptor
Small
Small
vasodilatati
on
on
Rash
Rash

Diphenhydrami
Diphenhydrami
de

Axon reflex

Itch
Itch