Bi 1 : Cho bit cc axtamin di y tng ng vi cc b m sao trn mARN nh sau. Vali(GUU), Alanin(GXX), Lxin(UUG), Lizin(AAA). a.

Hy xc nh trnh t cc axitamin trong on phn t prtin c t ng h p t o n gen c trnh t cc c p Nu nh sau. - XGG TTT XAA AAX - GXX AAA GTT TTG b.Mt on phn t prtin c trnh t cc axitamin nh sau. - Lxin alanin valin lizin Hy xc nh trnh t cc cp Nu trong on AND mang thng tin quy nh cu trc ca phn t prtin trn? Bi 2 : Cho bit tng b ba m sao trn mARN tng ng vi tng loi axitamin nh sau. GXX(alanin), AAG(lizin), UUU(phenyalanin), GAG(axit glutamic), GUX(valin), AAX(histidin), GAX(asparagin), UUA(L xin), AXX(tronin). a.Mt mch n AND c trnh t cc Nu nh sau. - ATG GXX AAG GAG TTT TTA - GTX GAX AAG TAG Bit rng mch i din vi mch ny lm khun tng hp nn phn t prin. Hy vit trnh t cc axitamin c trn phn t prtin c to thnh? b.Tnh chiu di ca phn t mARN do gen tng hp nn? c.Mt phn t prtin c trnh t cc axitamin nh sau. - Lizin axit glutamic histidin tronin valin lxin alanin phenyalanin asparagin Hy vit trnh t cc Nu trn mi mch ca phn t AND tng hp nn phn t prtin ni trn? Bi 3 : Mt mch ca phn t AND c trnh t cc Nu nh sau. - ATG GAG AXA AGG TAX XAA GTT AAT XXX GXG TTT TGX GGG TAG 1. Hy vit cc Nu trn mch n cn li ca phn t AND. 2.Tnh t l % v s lng tng loi Nu trn phn t AND? 3. Nu gen t nhn i 5 ln mi trng t bo cung cp bao nhiu Nu mi loi? 4. Tnh chiu di ca gen theo milimet? 5. Tnh khi lng phn t trung bnh ca phn t AND ny v tnh khi lng ca 10 phn t prtin do AND trn tng hp nn. Bit khi lng trung bnh ca 1 axitamin l 110 vC, Bi 4 : 1. Mt gen c chiu di 0,408 micromet, c th cha thng tin quy nh cu trc ca m t lo i prtin g m bao nhiu axitamin? 2.Phn t mARN c tng hp t gen s c chiu di l bao nhiu A 0 v gm bao nhiu riboNu? 3.Nu t l cc riboNu trong phn t ARN l . A, U, G, X ln lt phn chia theo t l 2 : 4 : 1 : 3. Th s l ng tng loi riboNu ca phn t ARN nh th no? T suy ra s lng tng loi Nu trn AND? 4.Nu ngc li cho bit t l % cc Nu trong mch ca gen th c th xc nh t l % cc lo i riboNu trn phn t ARN c tng hp t gen ni trn khng? Ti sao? Bi 5 : Mt gen cu trc gen ny tng hp mt phn t ARN c. 25 b ba GXX, 58 b ba UGX, 75 b ba AUX, 100 b ba AAA, hai b ba cn li thuc loi UAA v GUG. a.phn t prtin c tng hp t gen ni trn gm bao nhiu axitamin? b.c bit b ba m sao tng ng vi axitaimn nh sau. UAA = m kt thc, GUG : m m u. Th s axitamin mi loi trong phn t prtin bng bao nhiu? Bit GXX :alanin, UGX : xisteein, AUX :valin. c.Tnh s Nu tng loi trn mi mch ca gen v trn c phn t ca gen bng bao nhiu? Bi 6 : Hai phn t prtin A v B, mi phn t c cu to bi mt chui polipeptit v c t ng chiu di b c 1 l 2790 A0. Phn t prtin B c khi lng phn t t hn phn t prtin A l 7700 vC. a.Tm chiu di ca gen A v gen B quy nh s tng hp prtin ni trn? b.Tng s Nu loi A ca gen A vi tng s Nu loi G ca gen B l 2050, cn hiu gia chng l 50. Tm s lng tng loi Nu ca mi gen? c.Mch gc ca gen A tng hp nn phn t prtin A c A = 450, X = 250. Cn phn t mARN c t ng h p t gen B c Am = 120, Gm = 600. Tm s riboNu mi loi ca mi phn t ARN c tng hp t gen A v gen B? Bi 7 : Hai phn t prtin ang thc hin chc nng c tng hp t 2 phn t mARN c cu trc khc nhau. Kh i lng phn t ca 2 phn t prtin l 102300 vC. S lng axitamin ca phn t prtin 1 nhiu hn s axitamin ca phn t prtin 2 l 70 axitamin. a.Tm s axitamin trong mi phn t prtin? b.Tnh chiu di bc 1 ca mi phn t prtin? c.Trong qu trnh tng hp cc phn t prtin ni trn gii phng bao nhiu phn t n c t o nn cc lin k t peptit? d.Tm chiu di ca gen tng hp nn cc phn t prtin 1 v prtin 2 ? Bi 8 : C khong 10 loi prtin khc nhau c ghi mt m trn phn t AND.

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a.Nu mi phn t prtin gm khong 400 axitamin hon chnh th phn t AND ni trn c chiu di b ng bao nhiu? b.Khi phn t AND ni trn t nhn i 3 ln th mi trng cung cp bao nhiu nu t do ? c.Phn t mARN tham gia vo s tng hp mt loi prtin ni trn c bao nhiu riboNu ? C bao nhiu l t phn t tARN i vo riboxom tham gia tng hp nn phn t prtin ? Bi 9 : Khi lng ca mt on AND l 9.105 vC. on AND ny gm 2 gen cu trc, gen th nht di hn gen th hai l 0,102 micromet. Khi lng trung bnh ca 1 Nu l 300 vC. a.Xc nh chiu di ca mi gen? b.Tnh s axitamin ca mi phn t prtin c tng hp t cc gen ? c.Nu mi phn t mARN ca mi gen du c 5 riboxom trt qua 1 ln th s lt phn t tARN tham gia dch m l bao nhiu? (HNN I H Ni 1999) Bi 10 : Mt gen c 2880 lin kt hir, qu trnh phin m cn c cung cp 3600 riboNu t do. Mi phn t mARN u c 5 riboxom trt qua 1 ln. a.Tnh s Nu mi loi ca gen? b.Tnh s axitamin mi trng cung cp cho ton b qu trnh dch m? (olimpic 30/4 ln V) Bi 11 : Mt phn t mARN di 4080A0, c X +U = 30% v G U = 10% s riboNu ca mch. Mch khun ca gen tng hp phn t ARN c X = 30%, T = 40% so vi s Nu ca mch. Phn t mARN dng t ng h p cc phn t prtin. Bit rng mi trng ni bo cung cp 1995 axitamin cho vic t ng h p , v m i riboxom ch trt qua phn t mARN c1 ln. a.Tnh s lng tng loi Nu ca mi mch n ca gen v ca c gen? b.Tnh s lng tng loi riboNu ca 1 phn t mARN sinh ra t mch khun ca gen ? c.S lng phn t prtin tng hp v s lng riboxom tham gia vo qa trnh dch m ? (H Y DC H Ni 2000 ) Bi 12 : Mt gen ti sinhnhiu t trong mi trng cha ton b cc Nu c nh du. Trong cc gen con sinh ra thy c 6 mch n u cha cc Nu c nh du, cn 2 mch n cha cc Nu bnh th ng khng nh d u. Mch n th nht cha cc Nu khng nh du c A = 225, G = 375. Mch n th 2 ch a cc Nu khng c nh du c A = 300, G = 600. a.S lng tng loi Nu c nh du ly t mi trng ni bo phc v cho qu trnh ti sinh ni trn b ng bao nhiu? b.Khi gen m sao m 1 ln cn t l % v s lng tng loi riboNu trong mi trng bng bao nhiu? c.Gi thit rng b ba m sao kt thc l UAG th s lng tng loi riboNu trong cc b ba i m c a cc phn t tARN ti gii m 1 phn t mARN bng bao nhiu? ( 4 - TSH) Bi 13: Khi lng phn t ca 5 phn t prtin cng loi ang thc hin chc nng l 229900 vC. a.Tnh chiu di cu trc bc 1 ca phn t prtin? b.Tnh chiu di ca gen tng hp nn phn t prtin ny? c.Khi lng phn t ca ARN tng hp nn mi phn t prtin ny? Bi 14 : Mt phn t AND c A = 303000, G = 120000. a.Tnh chiu di ca AND theo mm ? b.Phn t And ni trn c th cha thng tin quy nh cu trc bao nhiu loi prtin, n u trung bnh m i lo i prtin gm 1000 axitamin? Bi 15 : Mt phn t ARN c Um =495 chim 15% tng s riboNu. a.Tnh chiu di ca gen tng hp nn phn t ARN ? b.Gen ny c th cha thng tin quy nh cu trc mt loi prtin gm bao nhiu axitamin th c hi n ch c nng ? c.C th tnh c % v s lng tng loi riboNu cn li ca phn t ARN hay khng ? Ti sao? Bi 16 : Mt on AND c chiu di 4630,8A0. on AND ny gm 2 gen cu trc, phn t prtin c tng hp t gen 1 c s axitamin nhiu hn s axitamin ca phn t prtin c t ng hp t gen th 2 l 50 axitamin. a.Tm s axitamin ca mi phn t prtin? b.Tm chiu di ca mi gen? c.Nu mi gen ni trn u phin m 3 ln, mi phn t ARN sinh ra u t o nn 5 phn t prtin th trong t t c prtin ny cha tng s bao nhiu lin kt peptit? Bi 17 : Gen th nht c 63 chu k xon. a.Tnh chiu di v khi lng trung bnh ca phn t prtin do gen 1 iu khin t ng hp? b.Tnh s lin kt peptit c hnh thnh v s phn t nc c gii phng hnh thnh nn cc lin k t peptit? c.Phn t prtin hon chnh c tng hp t gen th 2 cha 237 lin k t peptit. Xc nh chi u di c a gen th 2 v s phn t nc c gii phng? Bi 18 : Mt phn t ARN c chiu di 2784,6A0 tham gia qu trnh dch m a.Xc nh s lin kt peptit c thnh lp v khi lng phn t n c c gii phng? b.Tnh chiu di v khi lng phn t protin do gen ni trn tng hp?

c.Nu khi lng phn t nc c gii phng bng 39024 vC s c bao nhiu axitamin c cung cp cho qu trnh ?