CC PHNG PHP XC NH CU TRC HP CHT HU C BI TP

Bi tp 1 Cho H = 2.67519108 rads-1T-1 v C = 6.726107 rads-1T-1. My o ph c iu chnh phn tch proton tn s 250 MHz. a. Tnh gi tr ca cm ng t B0 tng ng. b. Vi gi tr B0 trn, xc nh tn s C ca u d s dng phn tch tn hiu cng hng ca 13C. c. Vi gi tr B0 trn, nhn 27Al cng hng ti 65.13 MHz. Nu mun s dng u d cng tn s C trn phn tch 27Al th cn iu chnh B0 gi tr no? Bi tp 2 Xc nh cng thc cu to cc hp cht sau da vo ph NMR ca chng. Bnh lun cc dch chuyn ha hc th hin trn ph.

Bi tp 3 Sau phn ng quang clo ha (photo-chlorination) toluen thu c hn hp sn phm c ph NMR 1H nh bn di. Xc nh cc sn phm thu c v t l gia chng?

Bi tp 4

Chn kt lun ng? Gii thch? A. Jab > Jac C. Jab < Jac

B. Jab = Jac D. cha thng tin kt lun

Bi tp 5 V dng tn hiu cng hng thu c ca proton Ha ghp spin vi 3 nhn b, c, d khc c spin I = 1/2, bit Jab = 10 Hz, Jac = 8 Hz, Jad = 7 Hz. Hp cht X (C5H10O) c 2 ng phn X1 v X2 vi cc ph NMR 1H v 13C{1H} nh bn di. a. Mu c ha tan trong dung mi no xc nh ph 13C{1H}? V sao mi dung mi xut hin dng mi 3? b. Phn tch ph NMR 1H v 13C{1H}ca X1 v X2 c. Xc nh cu trc X1 v X2

X1

X1

X2

X2

Bi tp 6 Ph NMR 1H ca dimethyl-cyclopropanedicarboxylate nh bn di. Cc hng s ghp spin (Hz) c cung cp trn nh cc mi a.

a. Cho bit ph ny tng ng vi ng phn cis hay trans ca hp cht?

cis

trans

b. Xc nh cc gi tr hng s ghp spin (Hz) c cung cp l ca cc nhn no, cch bao nhiu ni (xJXX)?