1

TIN HC NG DNG
TRONG SINH HC
(DHSH5)
Ths. Bi Hng Qun
09.09.25.24.19/09.17.27.26.25
Email: buihongquan@hui.edu.vn
Website: www.buihongquan.tk / www.gbd.edu.vn
Chng 1
GII THIU V CHNG
TRNH MS-EXCEL NG
DNG TRONG CNG NGH
SINH HC
Ths. Bi Hng Qun
09.09.25.24.19/09.17.27.26.25
Email: buihongquan@hui.edu.vn
Website: www.buihongquan.tk / www.gbd.edu.vn
2
Chng 2
NG DNG TIN HC
TRONG VIC LY MU
SINH HC
Ths. Bi Hng Qun
09.09.25.24.19/09.17.27.26.25
Email: buihongquan@hui.edu.vn
Website: www.buihongquan.tk / www.gbd.edu.vn
LY MU NGU NHIN
3
LY MU NGU NHIN
LY MU NGU NHIN
4
LY MU NGU NHIN
LY MU NGU NHIN
5
LY MU NGU NHIN
LOI GI TR BT THNG
6
Chng 3
NG DNG TIN HC
TRONG THNG K
SINH HC
Ths. Bi Hng Qun
09.09.25.24.19/09.17.27.26.25
Email: buihongquan@hui.edu.vn
Website: www.buihongquan.tk / www.gbd.edu.vn
CC NH NGHA
Gi tr trung bnh
(Mean, Average)
N
X
X
N
i
i
=
=
1
7
CC NH NGHA
Khong quan st: l khc bit gia hai gi tr
quan st: ln nht v nh nht.
r = Max Min
Gi tr trung bnh ging nhau, khong quan st
ging nhau?
Nu khong quan st ln th phn tn s cao.
CC NH NGHA
Gi tr trung v (Median) l gi tr din t khi
nim trung tm ca chui d liu.
1 2 3 4 5 6 7 8 9
200 201 202 203 204 206 207 207 209
Mu l n = 2m-1, x
0,05
= x
m
Mu chn n = 2m
2
1
5 , 0
+
+
=
m m
x x
x
8
CC NH NGHA
lch chun (Standard deviation): phn tn
ca d liu thng c din t bi phng sai
(variance) hay lch chun (cn s bc 2 ca
phng sai)..
) 1 (
) (
1
2

= =

=
N
X X
S SD
N
i
i
CC NH NGHA
Sai s chun ca gi tr trung bnh (Std. error of
the mean - SEM): gi tr trung bnh ca mu gn
bng gi tr trung bnh ca dn s hn l cc gi tr
quan st ring bit.
N
S
S X SD SEM
X
= = = ) (
9
CC NH NGHA
Gii hn v khong tin cy: Vi mt mc tin cy
(confidence level) nht nh l , gii hn tin cy
(confidence limits) ca mt gi tr trung bnh c
cho bi tch s (khi N<30: phn phi student):
LCL/UCL
X
S t

CC NH NGHA
Khong tin cy ca
gi tr trung bnh:
) , (
X X X
S t X S t X S t X

+ =
Gi tr thng k t (phn phi student) cn c thay
bi gi tr thng k z (phn phi chun) trong
trng hp N>30.
10
CC NH NGHA
H s phn tn (Coefficient of variation): sai s
tng i (relative deviation)
100
X
S
CV =
H s phn tn lin quan n lch chun (cng
nh chnh xc ca phng php o lng) v gi
tr trung bnh ca cc kt qu.
CC NH NGHA
Gi tr yu v (Mode): l gi tr c tn s cao nht
trong chui d liu.
Gi tr Kurt (Kurtosis): din t c im thuc v
nh ca dng phn phi d liu. + c nh, - bng
phng.

|
|

\
|


+
=

) 3 )( 2 (
) 1 ( 3
) 3 )( 2 )( 1 (
) 1 (
2
4
N N
N
S
X X
N N N
N N
KURT
i
11
CC NH NGHA
Gi tr SKEW (Skewness): phn nh mc bt i
xng ca dng phn phi d liu xung quanh gi tr
trung bnh. Skew
+
bt i xng, ui lch v gi tr
dng. Ngc li.

|
|

\
|


=

3
) 2 )( 1 ( S
X X
N N
N
SKEW
i
V D
12
CC NH NGHA
chnh xc
(precision): lp li
ca cc gi tr quan
st.
ng (Aceuracy):
trng hp gia cc
gi tr quan st (hay
thc nghim) vi gi
tr l thuyt.
100 ) 1 ( 100
X
S
CV P = =
100
_ _ _
binh trung tri Gia
thuyet ly tri Gia
A =
Chng 4
NG DNG TIN HC
TRONG PHN TCH
THNG K SINH HC
Ths. Bi Hng Qun
09.09.25.24.19/09.17.27.26.25
Email: buihongquan@hui.edu.vn
Website: www.buihongquan.tk / www.gbd.edu.vn
13
SO SNH GI TR TRUNG BNH
VI PHNG SAI BIT TRC
Nu N>30 th phng sai mu S
2
i c
th c xem
l phng sai dn s
2
, khi dng trc nghim z
test so snh gi tr trung bnh ca hai mu vi
phng sai bit trc. Z nh chp nhn H
o
.
H
o
:
1
=
2
H
o
:
1

2
2
2
2
1
2
1
2 1
2 1 ) ( ) (
N N
X X
z


+

=
SO SNH GI TR TRUNG BNH
VI PHNG SAI BIT TRC
14
SO SNH GI TR TRUNG BNH
VI PHNG SAI BIT TRC
SO SNH GI TR TRUNG BNH
VI PHNG SAI BIT TRC
15
SO SNH GI TR TRUNG BNH
VI PHNG SAI BIT TRC
SO SNH GI TR TRUNG BNH
VI PHNG SAI BIT TRC
16
SO SNH GI TR TRUNG BNH
VI PHNG SAI BIT TRC
SO SNH GI TR TRUNG BNH D
LIU TNG NG TNG CP
t test: paired two sample for means - N<30, ph
thuc, khng gi nh phng sai ca hai mu bng
nhau. Dng trc nghim t so snh.t nh chp nhn
H
o
.
1 _ _ _
) 1 (
) (
;
) 1 ( ;
/
1
2
1
=

= =
= =

=

= =
N Student phoi Phan
N
D D
S
N
D
D
N i Y X D
N S
D
t
N
i
i
D
N
i
i
i i i
D
D

17
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
18
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
KIM NH S NG NHT
CA HAI PHNG SAI
F-Test Two-Sample for variances: Thng dng so
snh chnh xc ca hai phng php nh lng.
F nh chp nhn H
o
:
1
2
=
2
2
(1-)100%; H
1
:
1
2
>
2
2
.
2 ; 1
_ _
2 2 1 1
2
2
2
1
2
2
2
1
2
1
2
2
= =
= =
N N
Fischer phoi Phan
S
S
S
S
F

19
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
t test: Two Sample Assuming Equal Variances:
N<30, c lp, c phng sai bng nhau. t nh chp
nhn H
o
.
2 _ _ _
2
) 1 ( ) 1 (
) ( ) (
2 1
2 1
2
2 2
2
1 1
2
2
1
2
2 1
2 1
+ =
+
+
=
+

=
N N Student phoi Phan
N N
S N S N
S
N
S
N
S
X X
t
p
p p

SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
20
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
21
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
22
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
SO SNH GI TR TRUNG BNH
VI PHNG SAI KHC NHAU
t test: Two Sample
Assuming Unequal
Variances: N<30,
c lp, c phng sai
khc nhau. t nh chp
nhn H
o
.
) (
1
) / (
1
) / (
) / / (
_ _
) ( ) (
2
2
2
2
2
1
2
1
2
1
2
2
2
2 1
2
1
2
2
2
1
2
1
2 1
2 1
ite Satterthwa Smith
N
N S
N
N S
N S N S
Student phoi Phan
N
S
N
S
X X
t

+
=
+

=

23
SO SNH GI TR TRUNG BNH
VI PHNG SAI KHC NHAU
SO SNH GI TR TRUNG BNH
VI PHNG SAI KHC NHAU
24
SO SNH GI TR TRUNG BNH
VI PHNG SAI KHC NHAU
SO SNH GI TR TRUNG BNH
VI PHNG SAI BNG NHAU
25
SO SNH T S
Trc nghim
2
: nh hn chp nhn H
o
. P (dng hm
chitest) ln hn chp nhn H
o
.
Tn s l thuyt = (tng hng x tng ct)/ tng cng
) 1 )( 1 ( _ _ ) (
) (
) (
2
1 1
2
2
1
2
2
= >
(
(

=
(

= =
=
c r df voi X P
E
E O
E
E O
r
j
c
j ij
ij ij
k
i
i
i i

SO SNH T S
26
SO SNH T S
SO SNH T S
27
SO SNH T S
SO SNH T S
28
KIM NH S NG NHT
CA NHIU PHNG SAI
Thng dng so snh chnh xc ca m phng
php nh lng (cng s mu. G nh chp nhn H
o
:

1
2
=
2
2
=
m
2
(1-)100%. G tra t bng phn v phn
b Cochran.
N
S
G
2
max
=
KIM NH S NG NHT
CA NHIU PHNG SAI

=
=
=
=
= =

=
|
|
|
|

\
|

+ =
(

\
|
=
m
i
i
m
i
i i
m
i
m
i
i
i
m
i
i
m
i
i
m n
s n
s
m n
n m
C
s ) n s m n
C
1
1
2
2
1
1
1
2
1
2
1
2
) (
) 1 (
1
1
1
) 1 ( 3
1
1
lg 1 ( lg
3026 , 2

Khc s mu,
2
nh, chp nhn H
o
.
29
PHN TCH PHNG SAI MT
YU T
Anova: Single factor: So snh gi tr trung bnh
ca hai hay nhiu mu c ly t cc dn s. M
rng ca trc nghim t hay z. Mc ch: nh gi
mc nh hng ca mt yu t (bin) ln gi tr
quan st (hm p ng). F nh chp nhn H
o
:
1
=

2
=
k
.
) _ _ _ (
) _ _ _ (
error of square Mean MSE
factor of square Mean MSF
F =
PHN TCH PHNG SAI
MT YU T
30
PHN TCH PHNG SAI
MT YU T
PHN TCH PHNG SAI
MT YU T
31
PHN TCH PHNG SAI HAI
YU T KHNG LP
Anova: Two factor without replication: nh gi
s nh hng ca hai yu t (bin) ln cc gi tr
quan st (hm p ng). F nh chp nhn H
o
:
1
=

2
=
k
.
PHN TCH PHNG SAI
HAI YU T KHNG LP
32
PHN TCH PHNG SAI
HAI YU T KHNG LP
PHN TCH PHNG SAI
HAI YU T KHNG LP
33
PHN TCH PHNG SAI HAI
YU T C LP
Anova: Two factor with replication: Trong mi
mc c s lp li ca k ln th nghim. nh gi s
nh hng ca hai yu t (bin) ln cc gi tr quan
st (hm p ng). F nh chp nhn H
o
:
1
=
2
=
k
.
Trong bng ANOVA c thm i lng tng tc
(interaction term) gia hai yu t.
PHN TCH PHNG SAI
HAI YU T C LP
34
PHN TCH PHNG SAI
HAI YU T C LP
PHN TCH PHNG SAI
HAI YU T C LP
35
Chng 5
NG DNG TIN HC
TRONG M HNH HO
SINH HC
Ths. Bi Hng Qun
09.09.25.24.19/09.17.27.26.25
Email: buihongquan@hui.edu.vn
Website: www.buihongquan.tk / www.gbd.edu.vn
PHN TCH TNG QUAN
Correlation: kho st khuynh hng v mc
lin quan. R<0,7 tng quan ngho nn (lng lo),
0,7-0,8: kh, 0,8-0,9: tt, >0,9 xut sc.
Thi gian m Nhit
Thi gian 1 ? ?
m 0.974654 1 ?
Nhit 0.77133 0.652367 1
) ( ) (
1
1
) , (

; ) (
1
) (
1
;
) , (
1 1
2 2
1
2 2
,
Y Y X X
N
Y X V O C Y
N
X
N
Y X COV
P
i
N
i
i
N
i
y i y
N
i
x i x
y x
y x

= =
= =

= =
=



36
PHN TCH TNG QUAN
PHN TCH TNG QUAN
37
PHN TCH HI QUY
Regression: xc nh s lin quan nh lng gia
hai bin s ngu nhin.
Phn tch hi quy tuyn tnh (linear regression).
H s hi quy B
i
c nh gi bng trc nghim t.
t nh, chp nhn H
o
: h s hi quy khng c
ngha.
S ph hp ca phng trnh hi quy vi thc
nghim c nh gi bng trc nghim F. F nh
chp nhn H
o
: phng trnh hi quy khng tng
thch.
CC GI TR THNG K
2 ; 1 : _ _ ;
2 : _ _
) (
;
2 1
2
2
2
2 2
= = =
=

= =

N v v Fischer phoi Phan

MSE
MSR
F
N Student phoi Phan
X X
S
S
S
B
S
B
t
i
b
b b
i i

38
C PHNG TRNH HI QUY
P value >0,05: Chp nhn H
o
: H s hi quy
khng c ngha.
Trc nghim t trong a tham s = N-k-1
Trc nghim F trong a tham s
1
=k;
2
=N-k-1.
F
s
: >0,05 : Chp nhn H
o:
phng trnh hi quy
khng thch hp.
PHN TCH TNG QUAN
39
PHN TCH HI QUY
PHN TCH HI QUY
40
QUY HOCH THC NGHIM
MA TRN PLACKETT-BURMAN (Sng lc
cc yu t - Screening factors)
MA TRN TAGUCHI OA
MA TRN (2 level factorial ) 2
n
MA TRN MT CONG P NG(RSM):
Thit k cu trc c tm (CCD), ma trn Box
Behnken.
TI U HO THCH NGHIQUY HOCH
TIN HO
GII THIU V QUY HOCH
THC NGHIM
u
vo
u ra
Qu trnh
Cc yu t c th kim sot
Cc yu t khng th kim sot
41
MC TIU CA QUY HOCH
THC NGHIM
Xc nh cc yu t nh hng (bin).
Xc nh xem gi tr no th cc yu t nh hng
lm cho hm p ng ti u.
Xc nh xem gi tr no th cc yu t nh hng
lm cho hm p ng ti thiu.
Xc nh xem t gi tr ca cc yu t nh hng
ti thiu ho nh hng ca cc yu t khng
th kim sot c.
MC TIU CA QUY HOCH
THC NGHIM
42
MC TIU CA QUY HOCH
THC NGHIM
MT S THIT K
Plackett Burman/ Taguchi OA/ D optimal/ A optimal.
Thit k 2
k
(fractional, confounding, fold over,
projection)
Cc thit k 3
k
Cc thit k phi hp mc
B tr Latin vung
Box - Behnken
Thit k cu trc c tm (vi cc im sao)
Johns
43
MICROSOFT OFFICE EXCEL 2003
Chc nng Solver
y l mt chc nng lm vic theo thut ton
vt cn. Chng trnh s thay i ln lt gi tr
cc bin theo tng bc nhy rt nh ri tnh gi
tr hm mc tiu tng bc nhy . Da vo
kh nng tnh ton nhanh, ta c th nhanh chng
tm ra im ti u y
max
.
SPSS 14.0
y l chng trnh chuyn dng cho phn tch
thng k, l sn phm ca cng ty SPSS, pht
hnh nm 2005.
Tuy chng trnh ny c rt nhiu tnh nng mnh
nhng i hi ngi s dng phi tm hiu hoc
c hun luyn k lng mi c th ng dng
hiu qu, phc v cng tc thng k. Trong khun
kh gii hn, n ny xin trnh by s nt v
mt s ng dng ca SPSS c lin quan n vic
tnh ton ti u ha.
44
GII THIU DESIGN EXPERT
Design-Expert 7.0.0 (DE) l mt sn phn ca tp on
Stat-Ease, c tung ra th trng nm 2005. DE c nh
gi l mt phn mm chuyn dng cho quy hoch thc
nghim.
Hin nay, DE h tr mt s chc nng mi nh sau:
Quy hoch theo m hnh yu t ton phn hoc tng phn
vi s bin ln n 21 trong 512 ln th nghim. Quy hoch
bc 1 tng qut: t 1 n 12 bin, mi bin c s mc khc
nhau t 2 n 999.
Ti u ha theo m hnh thnh phn tnh cht (Mixture
Designs)
M hnh CCD ln n 30 bin.
Thanh tiu
Thanh lnh (menu)
Thanh cng c
Danh sch chc nng
ng, m, thu nh ca s
Mn hnh lm vic chnh
GII THIU DESIGN EXPERT
45
GII THIU DESIGN EXPERT
Summary
Summary (hnh 3.5) l bng tng kt s b bao gm cc
thng tin v bin v hm mc tiu. Trong , cn ch hai
gi tr l lch chun (Std. Dev.) v t l (Ratio).
Std. Dev.: lch chun gia cc gi tr c c vi gi tr
trung bnh chung tng ng.
Ratio: t l gia gi tr cao nht v gi tr thp nht.
Fit summary
Bng Fit Summary (hnh 3.6) so snh mc tng thch
ca cc m hnh tnh ton hi quy. T , ngi s dng
c th nh hng chn m hnh trong cc bc sau. DE
s ngh cc m hnh thch hp (Suggested) v cnh bo
cc m hnh khng d liu thc hin (Aliased).
GII THIU DESIGN EXPERT
46
GII THIU DESIGN EXPERT
GII THIU DESIGN EXPERT
ANOVA
Bng ANOVA (hnh 3.7) trnh by cc kt qu kim nh
gii tch phng sai, v cc h s hi quy. Cc bin c
mc nh hng khng ng k, cc h s hi quy
khng c ngha, s khng ph hp vi thc
nghim,u c cnh bo cho ngi s dng.
Solutions
Bng Solutions (hnh 3.8) cho bit cc im th nghim
tm kim im ti u xung quanh cc tr ca b mt
p ng. Ngi s dng c ngh cc im ti u
theo iu kin nh trc.
47
GII THIU DESIGN EXPERT
Graph Columns
Graph Columns cho thy s tng quan gia hai
nhn t bt k, gip ta nhn bit s b cc mi
quan h gia hai cp bin. Ngoi ra, chng ta
cng c th nhn bit sm cc im th nghim
khng ng tin cy (Outlier) loi chng ra
khi qua trnh tnh ton hoc th nghim li
ly kt qu.
Design Model Graph
kim tra s bin i phng sai trong vng th
nghim, ta cn s dng trnh n Model Graph trong mc
Evaluation ca phn Designs.
DE 7.0.0 cho php s dng c th 3D hoc th dng
ng n bng cch chn la trong menu View.
Hp chn yu t
GII THIU DESIGN EXPERT
48
GII THIU DESIGN EXPERT
GII THIU DESIGN EXPERT
bt u mt qu trnh tnh ton ti u (Design)
mi, trn thanh menu, chn File New Design.
gi li mt d liu c, chn File Open
Design , hoc nhp t hp phm Ctrl+O.
lu li d liu ang s dng, File Save hoc
nhp t hp phm Ctrl+S
Khi m mt Design mi, chng trnh s ngh
la chn m hnh ti u trn bng danh sch chc
nng
49
GII THIU DESIGN EXPERT
bt u mt qu trnh tnh ton ti u (Design)
mi, trn thanh menu, chn File New Design.
gi li mt d liu c, chn File Open
Design , hoc nhp t hp phm Ctrl+O.
lu li d liu ang s dng, File Save hoc
nhp t hp phm Ctrl+S
Khi m mt Design mi, chng trnh s ngh
la chn m hnh ti u trn bng danh sch chc
nng
MA TRN PLACKETT-BURMAN
c pht minh ln u tin vo nm 1946.
Plackett - Burman
Dng sng lc cc yu t quan trong trong
nng nghip tng nng sut nng sn.
C th thit k t ng bng: Minitab, MSTAT,
Design expert, Toolbox, Mathlab, S-plus. . .
50
THIT K MA TRN 7 YU T
Row f1 f2 f3 f4 f5 f6 f7
r1 + + + - + - -
r2 - + + + - + -
r3 - - + + + - +
r4 + - - + + + -
r5 - + - - + + +
r6 + - + - - + +
r7 + + - + - - +
r8 - - - - - - -
GII THCH MA TRN
( - ) m ho mc di ca bin
( + ) m ho mc trn ca bin
r1 th nghim 1
f1 bin 1
Dng u tin/ Ct u tin c cho bi: Plackett
RL, Burman JP (1946) The design of optimum
multifactorial experiments. Biometrika 37:30525.
Cc dng tip theo c thnh lp bng cch ly
dng trc lin k t v tr 1 n v tr n-1 thnh
v tr th 2 n n ca dng tip theo.
51
TNH TON KT QU
Nhp s liu vo chng trnh my tnh tnh
ton t ng.
Tnh h s nh hng ca yu t th i bng cng
thc:
N
Y
E
N
r
ir
i

+
=
=
1
1
52
53
QUY HOCH THC NGHIM
YU T TON PHN 2
n
Mi t hp ca cc mc yu t u c thc hin
nghin cu.
k yu t v n mc N=n
k
. Hai mc th 2
k
. Hai u
bin.
Phng trnh hi quy c dng: = b
o
+ b
1
x
1
+ b
2
x
2
+
b
3
x
3
+ b
12
x
1
x
2
+ b
13
x
1
x
3
+ b
23
x
2
x
3
CU TRC CA MA TRN
Th nghim x
0
x
1
x
2
x
3
y
1
y
2
y
3
1 + - - - Gi tr hm p
ng y o bng thc
nghim. C th lm
3 th nghim tm
xc nh phng
sai ti hin ( lp
li ca th nghim)
2 + + - -
3 + - + -
4 + + + -
5 + - - +
6 + + - +
7 + - + +
8 + + + +
54
TNH TON V KIM NH
Fischer phoi phan
s
s
F
N
y y
s
student phoi phan
s
b
t
y y
s
y
y
N
s
s yi x
N
b
th
du
i
N
i
i
du
b
j
j
o
u
o
u
th
u
o
u
o
th
b
N
i
ji j
j
j
_ _ ; ;
1
) (
_ _ ; ;
1 3
) (
3
; ;
1
2
2
2
1 2
2
3
1 2
3
1
1
=

=
=

=
= = =

=
=
=
=
QUY HOCH THC NGHIM
YU T TNG PHN 2
n-p
Ch tin hnh mt s kt hp gia cc yu t. S
th nghim s gim.
k yu t v n mc N=n
k-p
. Hai mc th 2
k-p
. Hai u
bin.
Phng trnh hi quy 2
3-1
c dng: = b
o
+ b
1
x
1
+
b
2
x
2
+ b
3
x
3
. Trong x
1
x
2
c thay bng yu t
th ba.
55
MA TRN TYP 2
n-p
TYT 2
2
TYP 2
3-1
Th nghim x
o
x
1
x
2
x
1
x
2
x
o
x
1
x
2
x
3
1 + - - + + - - +
2 + + - - + + - -
3 + - + - + - + -
4 + + + + + + + +
Biu thc sinh x
3
=x
1
x
2
TNH TON V KIM NH
) 1 ( ; ; ); 1 ( ;
/ ; / ;
.
) (
; ;
1
) (
; : 1 ;
2 1 2
2
2 2 2 2 1
2
1 1
2
2
1
2
2
max
1
2
2 1
= = = = =
= = =

= = =

= = =

=
= =
=
= =
m N f l N f
s
s
F m N df
s
b
t
Nm s s m s s
N
y x
b
l N
y y m
s
N
s
s
s
s
G
m
y y
s N i
m
y
y
th
tt
b
j
j
th b th y
i
N
i
ji
j
N
i
i i
tt
N
i
i
th N
i
i
m
u
i iu
i
m
u
iu
i
j
j
56
TI U HO THEO NG DC NHT
thit lp c phng trnh hi quy vi y
cc kim nh.
Xut pht t im 0, chn bc nhy mi ca cc
yu t. C tnh n du ca cc h s.
Lm thc nghim tm im ti u.
2 2
3 3
2 3
2 2
1 1
2 1
;

=
b
b
b
b

CC PHNG N THC
NGHIM CP 2
Nghin cu b mt p ng (Response surface
methodology)
Cc phng n cu trc c tm (Central composite
design).
Ma trn Box Behnken.
Phng n quay bc hai Box Hunter
Thc hin trc tip trn my.
57
Gi tr ba yu t nghin cu trong
RSM-CCD
58
59
60
61
62
63
64
65
66
MT S PHNG N TI U
HO KHC
Ti u ho thch nghi- Quy hoch tin ho.
Quy hoch n hnh.
Ti u ho a mc tiu
Tham kho trong: Nguyn Cnh (2004) Quy hoch
thc nghim, NXB DHQG Tp.HCM.
TI LIU THAM KHO
ng Vn Gip (1997) Phn tch d liu khoa hc bng
chng trnh MS-Excel, NXB Gio Dc.
Chu vn Mn (2003) ng dng tin hc trong sinh hc, NXB
H QG h Ni.
Nguyn Cnh (2004) Quy hoch thc nghim, NXB HQG
Tp.HCM.
Nguyn Ngc Anh v cs. (2008) Phn tch thng k s dng
excel. DEPOCEN.
Plackett RL, Burman JP (1946) The design of optimum
multifactorial experiments. Biometrika 37:30525.
V mt s ti liu ting nc ngoi.