Bi 1: Khi ozon ha hai hp cht hu c A v B c cng CTPT C4H6Cl2 u thu c cc ozonit.

Sau khi thy phn ozonit, A cho 2,3-iclopropanal; B cho cloetanal. Xc nh CTCT ca A, B; vit phng trnh phn ng iu ch A v B t axetilen v cc cht v c cn thit. Bi 2: Hp cht thm A c cng thc C9H9Cl c cu hnh trans v rt d phn ng vi dung dch NaOH long (c khuy u v un nng nh) cho hn hp sn phm c cng thc C 9H10O. Vit CT cu trc ca A v cc sn phm. Bi 3: Xc nh sn phm th thu c khi un nh cis-1,4-imetylxiclohexyl bromua (hoc trans-1,4-imetylxiclohexyl bromua) trong dung dch NaOH long. (S: hn hp cis v trans) Bi 4: Hon thnh y cc s phn ng sau: a. (CH3)2CH-Br + Li A. b. C6H5Br + Mg/ete A1 c. CH3MgI
CO2
1. CH3COC2H5 2. H3O+

B1.

A2

H3O+

B2. A3
Mg/ete

d. CH3CH2CH=CH2

HBr, peoxit

B3

1. CH3COCH3 2. H3O+

C3.

e. CH3CH2CH2I X Y CH3(CH2)4OH. Bi 5: Hy sp xp cc cht sau theo trt t gim dn kh nng phn ng th SN2 CH3-CHBr-CH2-CH2-CH3 (a), (CH3)2CH-CH2-CH2Br (b), (CH3)2C=CBr-CH2-CH3 (c), (CH3)2C=CH-CH2Br (d). Bi 6: Hy ch ra nhng ch sai (nu c) trong nhng s phn ng sau y: a. HC CH + HCl CH2=CH-Cl CH2=CH-Cl + NaCN CH2=CH-CN + NaCN b. Br-CH2-CH2-Br + Mg BrMg-CH2-CH2-MgBr c. R-C CNa + Cl-(CH2)3-Br R-C C-(CH2)3-Br + NaCl Bi 7: Vit CTCT ca cc sn phm trung gian v cui cng trong cc dy chuyn ha sau: a. CH3CCl2CH3 (+ NaNH2 d) A (+ H2/Pd) B (+HBr/ROOR) C (+ Na) D. b. CH3CHBrCH3 (+ NaOEt) F (+ Br2/CCl4) G (+NaNH2) H (+ H3O+/Hg2+) J. c. HC CH (+ NaNH2 1 : 1) K (+ CH3Br) L (+ H2/Pd) M (+ HCl) N (+ C6H6/AlCl3). Bi 8: Hy sp xp cc cht sau theo trt t gim dn kh nng phn ng th SN1 Benzyl clorua (a), p-xianobenzyl clorua (b), p-metoxibenzyl clorua (c), p-metylbenzyl clorua (d), p-nitrobenzyl clorua (e). Bi 9: Cho xeton C5H10O (I) tc dng vi etylmagie bromua, sau thy phn ri tch nc hp cht ancol to thnh thu c anken (II), cht ny c ozon ha ri thy phn th cho dietyl xeton v axetandehit. Hy xc nh cu trc ca cht (I) v (II). Bi 10: iu ch cc sn phm sau y: a. 2-Brompropan (izopropyl bromua) t propanol-1. b. n-Propyl bromua t 1,2-dibrompropan. c. 2-Metoxibutan t n-butyl iodua. Bi 11: Vit CTCT cc sn phm to thnh trong phn ng gia cc hp cht sau y: a. 2-Clopropan v natri etylat. b. 2-Brombutan v KOH m c trong ru v un nng. c. 2-Brombutan v dung dch KOH long trong nc nhit thng.
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