Cancer How It Works and How You Win

Presented By

Leigh Erin Connealy, MD Center for New Medicine

6 Hughes, Suite 100 Irvine, CA 92618

www.centerfornewmedicine.com www.drconnealy.com

Cancer is the #1 Killer of People 1 to 85!

Number one health concern of every American. Every hour, 156 people will learn they have cancer. It is the NUMBER ONE KILLER of people 1 to 85 years of age. One in two will die of cancer Estimated Deaths Reported by American Cancer Society in 2009 562,340 (up from 552,200 in 2000) Number has been increasing despite drug and surgery innovations

Cancer is the #1 Killer of People 1 to 85!

Currently, if you are diagnosed with cancer you are given three options: SURGERY CHEMOTHERAPY

RADIATION In the Journal of Clinical Oncology, 2004, Chemotherapy has an average five year survival success rate of just over 2% for all cancers. Dr. Allen Levine, M.D. (The Healing of Cancer), The majority of cancer patients in this country, die because of chemo-therapy which has been documented for over a decade.?

What is Cancer?
By definition, cancer is the uncontrolled growth of abnormal cells. A cell or cluster of cells that is out of control. It has gone haywire and totally confused. Has lost its integrity and health. Every cell has the capacity to become a cancer cell under the right conditions. Cancer is fundamentality connected to mitochondrial dysfunction.

Most Common Forms of Cancer:

Skin cancer
1 million new cases a year

Most Common Forms of Cancer:

Lung cancer
215,00 new caser per year 161,000 die of lung cancer every year

Most Common Forms of Cancer:

Prostate
186,000 new cases per year 30,000 men die per year

Projected New Cases of Prostate Cancer*

Historical and Projected Deaths of Prostate Cancer*

*Johns Hopkins

Most Common Forms of Cancer:

Breast
182,000 new cases per year 40,000 women die every year from breast cancer

What Causes Cancer???

There Are over 30 Carcinogenic Factors and fall into three basic categories:

TOXINS BUGS BIOLOGICAL FACTORS

What Causes Cancer???

TOXINS Irradiated foodcontrolled amounts of ionizing radiation Additives-food colors, dyes, aspartame Mercury toxicity-tooth fillings Dental factors-root canals, infections Sunlight (UVB) EMF Geopathic stress-energies from the earth Sick building syndrome Ionizing radiation xrays, CT scans, etc. Nuclear radiation Pesticides Industrial toxins, heavy metals, & Xenoestrogen-plastics Polluted water Chlorinated water Fluoridated water Tobacco & smoking Immunosuppressive drugs and all drugs

What Causes Cancer???

BUGS Bacteria Fungus: molds, mildews, Candida Parasites Viruses

What Causes Cancer???

BIOLOGICAL FACTORS Diet and nutritional deficiency Toxic emotions (chronic stress) Depressed thyroid (gluten allergy, heavy metal toxins) Intestinal toxicity Hormone therapies (birth control, synthetic estrogens, hormone blockades, RBSt) Blocked detoxification (bad circulation, scars) Cellular oxygen deficiency (acidity, lack of exercise, pollution, lack of CO2) Cellular terrain (bugs grow when terrain is out of balance) Free radicals (highly charged chemicals that damage to mitochondria) Vaccines

Images courtesy of Wake-Up.TV

Images courtesy of Wake-Up.TV

Mitochondrial dysfunction has been definitively linked to virtually all killer diseases of aging.
The more functional mitochondria you have in your cells, the greater overall health and durability. As we age, our mitochondria degrade and become dysfunctional. Loss of functional mitochondria ultimately leads to a host of debilitating disorders followed by death of the organism. Free radicals cause mutations. The mutations interfere with a normal cell removal process know as APOPTOSIS.

GENETICS AND CANCER????

The New England Journal of Medicine studied 44,788 pairs of twins and determined the diet and lifestyle of were a better indicator of cancer risk than genetics.

Alkalize or Die
What is pH? Why should we be concerned? What makes you acidic? What makes you alkaline?

The Environments Role in Cancer(?)

The current level of chemicals in the food and water supply and the indoor and outdoor environment, have lowered our threshold of resistance to disease, and has altered our bodies metabolism causing enzyme dysfunction, nutritional deficiencies and hormonal imbalances, therefore, detoxification is necessary to protect against toxins that encourage tumor development and growth.

Images courtesy of Wake-Up.TV

Inflammation and Cancer

TOP 10 ARTICLES PUBLISHED
AGGARWAL BB, GEHLOT P: INFLAMMATION AND CANCER: HOW FRIENDLY IS THE RELATIONSHIP FOR CANCER PATIENTS? CURR OPIN PHARMACOL; 2009 AUG;9(4):351-69 WEBER D, WHEAT JM, CURRI GM: INFLAMMATION AND CANCER: TUMOR INITIATION, PROGRESSION AND METASTASIS, AND CHINESE BOTANICAL MEDICINES. ZHONG XI YI JIE HE XUE BAO; 2010 NOV;8(11):1006-13 MANTOVANI A: MOLECULAR PATHWAYS LINKING INFLAMMATION AND CANCER. CURR MOL MED; 2010 JUN;10(4):369-73 AGGARWAL BB, VIJAYALEKSHMI RV, SUNG B: TARGETING INFLAMMATOR Y PATHWAYS FOR PREVENTION AND THERAPY OF CANCER: SHORT-TERM FRIEND, LONG-TERM FOE. CLIN CANCER RES; 2009 JAN 15;15(2):425-30 MANTOVANI A, GARLANDA C, ALLAVENA P: MOLECULAR PATHWAYS AND TARGETS IN CANCER-RELATED INFLAMMATION. ANN MED; 2010 APR;42(3):161-70 AGGARWAL BB, KUNNUMAKKARA AB, HARIKUMAR KB, GUPTA SR, THARAKAN ST, KOCA C, DEY S, SUNG B: SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION-3, INFLAMMATION, AND CANCER: HOW INTIMATE IS THE RELATIONSHIP?. ANN N Y ACAD SCI; 2009 AUG;1171:59-76 DANESE S, MANTOVANI A: INFLAMMATORY BOWEL DISEASE AND INTESTINAL CANCER: A PARADIGM OF THE YIN-YANG INTERPLAY BETWEEN INFLAMMATION AND CANCER. ONCOGENE; 2010 JUN 10;29(23):3313-23 REUTER S, GUPTA SC, CHATURVEDI MM, AGGARWAL BB: OXIDATIVE STRESS, INFLAMMATION, AND CANCER: HOW ARE THEY LINKED? FREE RADIC BIOL MED; 2010 DEC 1;49(11):1603-16 RAJPUT S, WILBER A: ROLES OF INFLAMMATION IN CANCER INITIATION, PROGRESSION, AND METASTASIS. FRONT BIOSCI (SCHOL ED); 2010;2:176-83 YU H, PARDOLL D, JOVE R: STATS IN CANCER INFLAMMATION AND IMMUNITY: A LEADING ROLE FOR STAT3. NAT REV CANCER; 2009 NOV;9(11):798-809

WAR on CANCER
President Richard Nixon signing the National Cancer Act on December 23, 1971

Change in the US Death Rates* by Cause,

600 500 400 300 200 100 0 586.8

1950 & 2002

1950 2002

Rate Per 100,000

240.1 180.7 193.9 193.4

56.0 Heart Diseases Cerebrovascular Diseases

48.1

22.5 Cancer

Pneumonia/ Influenza

* Age-adjusted to 2000 US standard population. Sources: 1950 Mortality Data - CDC/NCHS, NVSS, Mortality Revised. 2002 Mortality Data: US Mortality Public Use Data Tape, 2002, NCHS, Centers for Disease Control and Prevention, 2004

Global Prostate cancer Incidence per 100,000 (Age-stanardized) in 2002

USA China India Bangladesh

124.8 1.6 4.4 0.3

Projection for Global Cancer Incidence and Cancer Deaths

25
New Cases Deaths 20 16

20

Millions

15
10 10 7

14

10 5 0

2002

2020

2030

Cancer Is a Preventable Disease That Requires Major Changes in Life Style

40

Cancer Incidence (%)

35
30

30

20

14-20

18

10

7 5-10
0 Tobacco Diet Obesity Infections E. Pollution Genes & Radiations

HK 04-14-2008

Anand P, Harikumar K and Aggarwal BB; Pharmaceutical Research, 2009

Colorectal Cancer and Red Meat!

Colorectal cancer is the second most common cause of cancer deaths in affluent countries. Processed red meat (beef, mutton, lamb, veal, pork, and offal) intake is closely linked with the risk of CRC. Dietary modification can reduce this cancer burden by 70%. Heterocyclic amines, high saturated fat, carcinogenic Nnitroso compounds, high protein cholesterol and salt contents and heme iron are some of the components of meat linked with CRC.
Bastide NM, CAPR, 2011

Working Hypothesis:
Dysregulated chronic inflammation caused by life style factors mediate chronic diseases including cancer!

"Why We're Losing the War on Cancer?

(And How to Win It?)
2004; Fortune cover story

TIME Feb. 23, 2004

What is Inflammation?
Cornelius Celsus,
a physician in first century Rome:

Heat (calor) Pain (dolor) Redness (rubor) Swelling (tumour)

21

Inflammation and cancer

Redness, swelling, heat and pain

Rudolf Virchow (1821-1902; in 1850)

His Pathology laboratory in Wurzburg, Germany

Linked Inflammation with atherosclerosis, rheumatoid arthritis, multiple sclerosis, cancer, asthma, Alzheimers From Heidland A et al, History of Nephrology, 2006 22

Inflammation as a risk factor for most cancers

Inducer % predisposed progress to cancer Tobacco smoke Bronchitis Lung Cancer 11-24 Helicobacter pyloriGastritis Gastric Cancer 1-3 Human papilloma virus CervicitisCervical cancer <1 Hepatitis B & C virus HepatitisHCC 10 Bacteria, GBS Cholecystitis Gall bladder cancer 1 2% Gram- uropathogens Cystitis Bladder cancer <1 Tobacco, genetics Pancreatitis Pancreatic cancer 10% GA, alcohol, tobacco Esophagitis Esophageal cancer 15 Asbestos fibers Asbestosis Mesothelioma 1015 Epstein-Barr virus Mononucleosis Burkitts lymphoma <1 Hodgkins disease Gut pathogens IBD Colorectal cancer 1* Ultraviolet light Sunburn Melanoma 9% Infections, STD PIA Prostate cancer ?
GA, gastric acid; GBS, gall bladder stones; HCC, hepatocellular carcinoma; STD, sexually transmitted diseases; PIA, prostate inflammatory atrophy.
From: Aggarwal BB, et al. Inflammation and cancer: How hot is the link? Biochemical Pharmacology, 72, 2006, 1605-21

Inflammation

Cancers

Hypothesis!
NF-B activation is a major mediator of inflammation in most chronic diseases (including cancer) & inhibition of NF-B can prevent/delay the onset of the chronic diseases!

NF-kappa B activation has been linked to most major diseases

Kumar A, Takada Y, Boriek AM, Aggarwal BB. Journal of Molecular Medicine 2004;82:434-48.

Alcoholic beverages Ultraviolet radiation

Environmental pollutants
Industrial pollutant, Diesel, Acid rain

Stress
pH, hypoxia, heavy metals, chemotherapy

Potential Sources of Inflammation

Cigarette smoke

Food Factors Grill, Fried, red meat

Bacteria
Helicobacter pylori Salmonella typhi Chlamydia pneumoniae Streptococcus bovis Escherichia coli

Viruses
Herpes simplex virus 8, Hepatitis viruses, HPVs,HIV, EBV

Different faces of inflammation and its role in tumorigenesis

Stress
(Chemical, physical,and psychological)

Environmental pollutants
(Cigarette smoke, Diesel)

Viruses

(HTLV1, HPV,HCV, HBV, EBV )

Food Factors
(Grill, Fried, red meat)
Reactive oxygen species Tumor necrosis factor Interleukin-1 Interleukin-6 Iinterleukin-8 Interleukin-18 Nuclear Factor-B Hypoxia-inducible factor Cyclooxygenase-2 5-Lipooxygenase Inducible nitric oxidesynthase Matrix metalloproteinase-9 Chemokines

Bacteria
(e.g; Helicobacter pylori )

Acute
inflammation
Innate Immunity Humoral immunity Immune surveillance

Chronic inflammation
Tumor cell survival Tumor cell proliferation Tumor cell invasion Tumor angiogenesis Tumor metastasis Tumor chemoresistance Tumor radioresistance

Therapeutic inflammation

Pathological inflammation

Aggarwal BB, et al. Inflammation and cancer: How hot is the link? Biochem Pharmacol. 2006

NF-B expression in the pathogenesis of lung cancer

AAH N o r m a l E p ith e liu m H y p e r p la s ia

S q u a m o u s M e ta p la s ia

M o d e r a te D y s p la s ia

C a r c in o m a In S itu

Tang et al, 2006

Obesity and Cancer

Esophageal cancer Multiple myeloma Renal cancer Gastric cancer Non-Hodgkins lymphoma Cervical cancer Colon cancer

Obesity
14% 20%

Gall bladder cancer

Pancreatic cancer Rectal cancer Uterine cancer

Ovarian cancer

Breast cancer Liver cancer Endometrial cancer

Anand P, Harikumar K and Aggarwal BB; Pharmaceutical Research, 2009

Circulating mononuclear cells in the obese are in a proinflammatory state

Ghanim H, Aljada A, Hofmeyer D, Syed T, Mohanty P, Dandona P.

Circulation.
2004 Sep 21;110(12):1564-71.

Obese subjects express higher levels of activated NF-kB than lean subjects
Lean Obese

NF-kB

Modified from Ghanim H, 2004

Aggarwal BB. Cancer Cell. 2004 Sep;6(3):203-8.

NF-B: the enemy within.

NF-B

NF-B : a friend or a foe in cancer?

Shishodia S, Aggarwal BB. Biochem Pharmacol. 2004;68:1071-80.

Signalling pathways of the TNF superfamily: a double-edged sword.

Aggarwal BB. Nature Rev Immunol. 2003;3:745-56.

Role of inflammation in tumorigenesis

NF-B
DNA damage Oncogenes Bcl-xl Bcl-2 Survivin C-FLIP cIAP-1 cIAP-2 XIAP Cyclin D1 C-myc TNF IL-1 IL-6 COX2 MMP-9 uPA ICAM-1 ELAM-1 VCAM-1 VEGF CXCR4 TWIST

Transformation

Tumor suppression

Normal Normal cell cell Normal cell

Transformation

Survival

Proliferation Proliferation

Invasion Invasion

Angiogenesis

Metastasis

10-20 10-20Years Years

10 Years

Inflammation Inflammation

Aggarwal etal, CCR, 2010

Ekbom A, 1998

Constitutive activation of NF-B has been linked with most cancers

Esophageal cancer Colon cancer Laryngeal cancer Pharyngeal cancer Pancreatic cancer Renal carcinoma

Head and neck SCC

Lung cancer

Bladder cancer

Tobacco-linked cancers
Acute Myelogenous leukemia Hodgkins disease Non-Hodgkins lymphoma B cell lymphoma T cell lymphoma Mantle cell lymphoma Multiple myeloma Acute lymphoblastic leukemia Thyroid cancer Liver cancer

Carcinogens

NF-B

Carcinogens

Breast cancer Ovarian cancer Prostate cancer

Viral cancers
Adult T cell leukemia Cervical cancer Nasopharyngeal carcinoma

UV light
Melanoma

Shishodia and Aggarwal, Biochemical Pharmacology, 2004

NF-kB and FDA Approved Anticancer Drugs

Herceptin Tykerb Erbitux Iressa Vectibix Humira Remicade Revlimid Enbrel Sutent Sprycel Avastin Sutent Nexavar Gleevec Sprycel Tasigna

HER2

EGFR

TNF

PDGFR

VEGFR

Bcr-Abl

mTOR

Afinitor Torisel

Proteasome

Velacade

NF-B
Chaturvedi etal, 2010

How to suppress NF-B activation safely!

Requirements of Chemopreventive agents

Should be non-toxic to normal and healthy people. Should have high efficacy against multiple sites. Should be orally bio-available. Should have known mechanism of action. Should be easily available. Should be low-cost. Should be acceptable to most human population.
BBA-8-24-08

If someone invented a pill to cut a cancer risk in half, would you take it?
Among 1,000 women, 19 would be expected to develop breast cancer over the next five years but if those women all took tamoxifen, however, 9 of those women would avoid breast cancer Tamoxifen is expected to cause 21 additional cases of endometrial cancer, a cancer of the uterine lining that is typically treatable when caught early. An additional 21 would develop blood clots, 31 would develop cataracts and 12 would develop sexual problems. More than half of the 1,000 women would naturally develop hormonal symptoms like hot flashes, changes in vaginal discharge or irregular periods, tamoxifen would cause those symptoms in about an additional 120 women. Raloxifene, which has been shown to significantly reduce breast cancer risk but with fewer side effects. Although the data has not yet been published, she said the findings appeared to be similar. New York Times, Dec 14th, 2009

Chronic diseases caused by chronic inflammation requires chronic treatment!

.Sloan School of Management at M.I.T. and the Harvard Business School has created Pharmers Market, however, we need a Farmers Market
New York Times, November, 2009

Farmers Market

Fruits

Spices & condiments

Vegetables

Anand P, Harikumar K and Aggarwal BB; Pharmaceutical Research, 2009

Cereals

Hippocrates proclaimed ~2500 years ago

Let food be thy medicine and medicine be thy food

183

To treat/prevent most chronic diseases, we need to dial down but not turn off of multiple, not single gene

Most diseases including cancer is due to dysregulation of multiple genes. Mono-targeted drugs are unlikely to be an effective therapy. Multi-targeted drugs are needed Most natural products are designed for multi-targeting, naturally.

Change in Paradigm!

Identification of inhibitors of NF-B from natural sources

Golden Triangle
Modern Technology

Traditional Knowledge
(Traditional Chinese Medicine Ayurvedic Medicine Egyptian Medicine Kampo)

Modern Knowledge
(Allopathic Medicine)

Aggarwal BB, et al Expert Opin Ther Targets. 2006;10:87-118.

F10
Chemo drugs Receptor ligands Cytokines Environmental pollutants Oxidative stress Interleukins Fungus Obesity Growth factors Tobacco Sun exposure
Endotoxins

Carcinogens
Hormones

Viruses Bacteria

-radiation Physiological stress

TNF Family Glucose

Heavy metals

Mitogens

NF-B Inflammation

Carcinogens Leishmania

Alcohol

Glycyrrhizic acid Lycopene Plumbagin Berberine Morin Mangiferine Fisetin

Allicin

Caffeic acid

Capsaicin

Stigmasterol Apigenin Thymoquinone

Chemopreventive agents
Geraniol Genistein Celastrol

Tocotrienol Quercetin Myrcetin Anethole Catechin Ellagic acid Lupeol Gossypin Piperine

Zerumbone Silymarin

Xanthohumol Diosgenin Phytic acid Rutin

Kaempferol

Indole-3-carbinol Ascorbic acid

Pantothenic acid

Tocopherol Ursolic acid

Betulinic acid Gingerol Luteolin

Curcumin

Sanguinarine

Sulphoraphane

Delphinidine Gambogic acid Avenanthramide Eugenol

Resveratrol

Resveratrol can block NF-kB Activation

Aggarwal etal, 2004

Indole-3-Carbinol can block NF-kB activation

Aggarwal etal, 2004

Tocotrienols, the Vitamin E of the 21st Century:

Its Potential Against Cancer and Other Chronic Diseases
Aggarwal BB, Sundaram C, Prasad S., and Kannappan R. Biochemical Pharmacology 2010 Dec 1;80(11):1613-31.

Natural Sources ofTocotrienols

Palm

Elaeis guineensis

Rice

Barley

Oat

Wheat

Oryza sativa

Hordeum distichon

Avena sativa

Triticum vaccinium
http://www.tocotrienol.org/index.html

Sources of tocotrienols
Red annatto Palm oil
940 mg/kg

Barley
910 mg/kg

Rice bran
465 mg/kg

Grape fruit seed oil

380 mg/kg

Oat
210 mg/kg

Hazelnut
209 mg/kg

Maize
200 mg/kg

Wheat germ oil

189 mg/kg

Olive oil
180 mg/kg

Buckthorn Berry 130

mg/kg

Rye
92 mg/kg

Flax seed oil

25.1 mg/kg

Poppy seed oil

20.5 mg/kg

Safflower oil
11.8 mg/kg

From: Red annatto, Barrie, Tan; Palm oil, Schroeder,2006; Rice bran, Sookwong,2010; Grape fruit seed oil, maize, Wheat germ oil-Hassanein, 2009; Hazel nut, Amaral, 2006; Olive oil, Cunha, 2006; Buckthorn berry, Kallio, 2002; Rye-milagros Delgado-Zamarreno, 2009; Oat and barley, Panfili, Fratianni.200; Flax oil, poopy oil, safflower oil, Bozan, 2008

From Aggarwal et al, 2010

From exotic spice to modern drug?

Singh S. Cell. 2007 Sep 7;130(5):765-8.
The global demand for more affordable therapeutics and concerns about side effects of commonly used drugs are refocusing interest on Eastern traditional medicines, particularly those of India and China.

How Do I Know If I Have Cancer?

CA Profile Blood Test
Checks Levels Of:

HCG suppresses immunity and promotes cancer. three different types. PHI PHI is the enzyme that channels cells into anaerobic metabolism, or fermentation. CEA CEA is a broad spectrum cancer marker. GGTP GGTP is the most sensitive test for the liver. TSH TSH or thyroid stimulating hormone regulates metabolic rate. DHEA-S DHEA-S is the adrenal anti-stress, pro immunity, longevity hormone.

How Do I Know If I Have Cancer?

MRI, biopsy, mammography and CT and PET scans

How Do I Know If I Have Cancer?

MRI, biopsy, mammography and CT and PET scans Thermography
An alternative to mammograms Measures infrared heat from the body It can detect 86% of non palpable breast cancers It can detect a pathologic state of the breast up to ten years before a cancerous tumor can be found

How Do I Know If I Have Cancer?

C Reactive Protein which is a marker for inflammation
Inflammation is designed to heal and repair the body. Inflammation also neutralizes white blood cells and natural killer cells.

Power Doppler Sonography for breast and prostate

Safe, painless, and inexpensive

Non-Vascular vs. Vascular

Cancerous Tumor

Mammogram Negative

Suspicious Lesion
Mammogram Negative

Mammogram Negative MRI Positive

4/10/08

12/11/08

3/26/09

The Mind-Body Connection

Physicians have long associated psychological stresses with cancer. 2000 years ago, Greek physician Galen observed that depressed people were particularly prone In 1759 an English surgeon wrote that cancer went along with disasters in life, as occasion much trouble and grief. Can we really bring on our own cancer?

Dr. Hamers Laws:

Dr. Hamer hypothesized that all bodily events are controlled from the brain, he analyzed his patients brain scans and compared them with their medical records. Dr. Hamer discovered that every diseasenot only cancer!is controlled from its own specific area in the brain and linked to a very particular, identifiable, conflict shock. He called his findings The Five Biological Laws of the New Medicine

Dr. William Kelly

( November 1, 1925 January 30, 2005)

According to Dr. Kelly, there are a number of warning signs that start as small physical clues before the disease manifests more aggressively.

Dr. William Kelly Cancer Signs Doctors Often Miss

Failing eyesight (together with other signs, and not just as a symptom of aging) An attack of serious indigestion can be the first sign of cancer, caused by a blood clot in the pancreas that disables from 10% to 75% of its function, leading to a short supply of pancreatic enzymes that in turn allow the growth of tumors. Chronic fatigue--a characteristic shared by most cancer patients.

Dr. William Kelly

Brain fog--fuzzy-thinking: lost clarity of thought. Hair--brittle and coarse, balding and graying. Hernia--a symptom of many malignancies, as protein is "stolen" from large muscle masses. A peculiar odor--comes from cancer that doesn't wash away. Others may think of it as a "sickroom smell," or just "death." Muscle pains particularly in the back and shoulders. Depression

The Body in Balance Wining the War on Cancer Rule of thumb: Whatever you were doing when you got sick--don't do that anymore. If you want to change the way you feel, you must change the way you live.

Must DO List
Identify food allergies/intolerances Blood type diet Mostly raw, organically grown food Make sure your pH (acid/alkaline) balance is alkaline (7) Get all the essential nutrients:
Minerals Essential fatty acids, omega 3 and 6 oils (avoid hydrogenated oils like margarine and shortening at all costs) Amino Acids Digestive Aids Pancreatic Enzymes Vitamin D

Sleep Exercise

DO NOT List
Avoid:
tobacco alcohol soda preserved and pickled foods SUGAR, cookies, candy, pies, cakes, processed flour unfavorable carbohydrates fast food and processed food

Detoxification
Before any disease can be cured, the waste product and impurities must be cleansed from the body. The sooner this cleansing is done, the sooner the body can begin repairing itself. We have 70 to 100 trillion cells in our bodies. Therefore, we have at least 70 trillion garbage cans. Detox is just as important as nutrition.

7 Channels of Detoxification
Bowel Blood Skin Kidneys Lymphatic System Lung Liver

Detoxification
The Liver is the master gland of detoxification - Proper liver function keeps the heart, the brain, the kidney, and the pancreas disease free

Normal Liver

Fatty Liver

Cirrhosis of Liver

DETOXIFICATION Must DO List

Water, Water, Water!!! Parasite cleanse Liver/Gallbladder flush Coffee enemas Green juices (barley grass or wheatgrass) Carrot juice with celery and beets (some health food stores carry powdered carrot and beet juices)

DETOXIFICATION Must DO List

Far Infra-red sauna Foot detoxing Chelation (Oral or IV) Lymphatic drainage Zeolite Skin brushing Reduce stress (detoxify the mind) Exercise Emotional Detox Meditation

Reduce Emotional Stress

Images courtesy of Wake-Up.TV

The ANSWER will only be found by putting together all the pieces of the puzzle. We must assess and treat ALL the imbalanced systems:
Nutritional Hormonal Inflammation Immune Toxicity Energy Balancing Oxidative Stress Mind/Body

Seven Steps to Getting Started

Get honest DO YOU WANT TO LIVE? Personal inventory Appropriate tests and evaluations What specific changes do I need to make Make a plan Commit to a plan Just Start Now

GET READY FOR THE BEST VERSION OF YOURSELF

REVIEW
We have an enemy and its cancer We have to do what it takes to get the body in balance Realize that we are a mind/body/spirit and HAVE to stay positive despite the challenges We have EVERYTHING available to win the war on cancer We create a plan We work the plan Expect the Best

It is more important to know what sort of person has a disease than to know what sort of disease a person has.
-- Hippocrates (460-377 B.C.)

CONCLUSION
Prevention is the most important and reliable cancer fighting tool that exists today. That fact that cancer can be treated and reversed and that it can be detected early and prevented are the most important messages.

Cancer is Curable Now