You are on page 1of 82

MEDICAL SURGICAL

Overview of the Structures & Functions of Nervous System Central NS PNS ANS Brain & spinal cord 31 spinal & cranial sympathetic NS Parasypathatic NS

Somatic NS C- 8 T- 12 L- 5 S- 5 C- 1 ANS (or adrenergic of parasympatholitic response) SNS involved in fight or aggression response Release of norepinephrine (adrenaline cathecolamine) Adrenal medulla (potent vasoconstrictor) Increases body activities VS = Increase Except GIT decrease GITmotility * Why GIT is not increased = GIT is not important! Increase blood flow to skeletal muscles, brain & heart. I. SNS: Adrenergic Agents Epinephrine (adrenaline) Anticholinergic , Sympathomimetic, Parasympatholytic -Atropine sulfate II. PNS: Cholinergics, Beta Adrenergic blockers, Sympatholitic, Parasympathomimetic Beta adrenergic blocking agents (opposite of adrenergic agents) (all end in lol) - Blocks release of norepinephrine. - Decrease body activities except GIT (diarrhea) Ex. Propanolol, Metopanolol SE: B broncho spasm (bronchoconstriction) E elicits a decrease in myocardial contraction T treats HPN A AV conduction slows down Given to angina & MI beta-blockers to rest heart Anti HPN agents: 1. Beta blockers (-lol) 2. Ace inhibitors (-pril) ex ENALAPRIL, CAPTOPRIL 3. Calcium antagonist ex CALCIBLOC or NEFEDIPINE Peripheral nervous system: cholinergic/ vagal or sympatholitic response - Involved in fly or withdrawal response - Release of acetylcholine (ACTH) - Decrease all bodily activities except GIT (diarrhea) I Cholinergic agents ex 1. Mestinon Antidote anti cholinergic agents Atropine Sulfate S/E SNS Effect of PNS: (cholinergic) 1. Meiosis constriction of pupils 2. Increase salivation 3. BP & HR decreased 4. RR decrease broncho constriction 5. Diarrhea increased GI motility 6. Urinary frequency 7. Acetylcholine- neurotransmitter 8. Blood vessels- vasodilated Effects of SNS (anti-cholinergic/adrenergic) 1. Dilate pupil to aware of surroundings - medriasis 2. Dry mouth 3. BP & HR= increased 4. RR increased- broncho dilation 5. Constipation & urinary retention 6. Nor/Epinephrine- neurotransmitter 7. Blood vessels-vasoconstriction

S/E- of anti-hpn drugs: 1. orthostatic hpn 2. transient headache & dizziness.-Mgt. Rise slowly. Assist in ambulation. CNS (brain & spinal cord) I. Cells A. neurons Properties and characteristics a. Excitability ability of neuron to be affected in external environment. b. Conductivity ability of neuron to transmit a wave of excitation from one cell to another c. Permanent cells once destroyed, cant regenerate (ex. heart, retina, brain, osteocytes) Regenerative capacity A. Labile once destroyed cant regenerate - Epidermal cells, GIT cells, resp (lung cells). GUT B. Stable capable of regeneration BUT limited time only ex salivary gland, pancreas cells cell of liver, kidney cells C. Permanent cells retina, brain, heart, osteocytes cant regenerate. 3.) Neuroglia attached to neurons. Supports neurons. Where brain tumors are found. Types: 1. Astrocyte 2. Oligodendria Astrocytoma 90 95% brain tumor from astrocyte. Most brain tumors are found at astrocyte. Astrocyte maintains integrity of blood brain barrier (BBB). BBB semi permeable / selective -Toxic substance that destroys astrocyte & destroy BBB. Toxins that can pass in BBB: 1. Ammonia-liver cirrhosis. 2. 2. Carbon Monoxide seizure & parkinsons. 3. 3. Bilirubin- jaundice, hepatitis, kernicterus/hyperbilirubenia. 4. 4. Ketones DM. OLIGODENDRIA Produces myelin sheath wraps around a neuron acts as insulator facilitates rapid nerve impulse transmission. No myelin sheath degenerates neurons Damage to myelin sheath demyellenating disorders

DEMYELLENATING DSE 1.)ALZHEIMERS DISEASE atrophy of brain tissue due to a deficiency of acetylcholine. S&Sx: A amnesia loss of memory A apraxia unable to determine function & purpose of object A agnosia unable to recognize familiar object A aphasia - Expressive broccas aphasia unable to speak - Receptive wernickes aphasia unable to understand spoken words Common to Alzheimer receptive aphasia Drug of choice ARICEPT (taken at bedtime) & COGNEX. Mgt: Supportive & palliative.

Microglia stationary cells, engulfs bacteria, engulfs cellular debris. II. Compositions of Cord & Spinal cord 80% - brain mass 10% - CSF 10% - blood MONROE KELLY HYPOTHESIS: The skull is a closed vault. Any increase in one component will increase ICP. Normal ICP: 0-15mmHg

Brain mass Connects R & L cerebral hemisphere - Corpus collusum Rt cerebral hemisphere, Lt cerebral hemisphere Function: 1. Sensory 2. Motor 3. Integrative Lobes 1.) Frontal a. Controls motor activity b. Controls personality development c. Where primitive reflexes are inhibited d. Site of development of sense of umor e. Broccas area speech center Damage - expressive aphasia 2.) Temporal a. Hearing b. Short term memory c. Wernickes area gen interpretative or knowing Gnostic area Damage receptive aphasia 3.) Parietal lobe appreciation & discrimation of sensory imp - Pain, touch, pressure, heat & cold 4.) Occipital - vision 5.) Insula/island of reil/ Central lobe- controls visceral fx Function: - activities of internal organ 6.) Rhinencephalon/ Limbec - Smell, libido, long-term memory Basal Ganglia areas of gray matte located deep within a cerebral hemisphere - Extra pyramidal tract - Releases dopamine- Controls gross voluntary unit Decrease dopamine (Parkinsons) pin rolling of extremiies & Huntingtons Dse. Decrease acetylcholine Myasthenia Gravis & Alzheimers Increased neurotransmitter = psychiatric disorder Increase dopamine schizo Increase acetylcholine bipolar MID BRAIN relay station for sight & hearing Controls size & reaction of pupil 2 3 mm Controls hearing acuity CN 3 4 Isocoria normal size (equal) Anisocoria uneven size damage to mid brain PERRLA normal reaction DIENCEPHALON- between brain Thalamus acts as a relay station for sensation Hypothalamus (thermoregulating center of temp, sleep & wakefulness, thirst, appetite/ satiety center, emotional responses, controls pituitary function. BRAIN STEM- a. Pons or pneumotaxic center controls respiration Cranial 5 8 CNS MEDULLA OBLONGATA- controls heart rate, respiratory rate, swallowing, vomiting, hiccups/ singutus Vasomotor center, spinal decuissation termination, CN 9, 10, 11, 12 CEREBELLUM lesser brain - Controls posture, gait, balance, equilibrium 1. Cerebrum largest -

Cerebellar Tests: a.) R Rombergs test- needs 2 RNs to assist - Normal anatomical position 5 10 min (+) Rombergs test (+) ataxia or unsteady gait or drunken like movement with loss of balance. b.) Finger to nose test (+) To FTNT dymetria inability to stop a movement at a desired point c.) Alternate pronation & supination Palm up & down . (+) To alternate pronation & supination or damage to cerebellum dymentrium Composition of brain - based on Monroe Kellie Hypothesis - Skull is a closed container. Any alteration in 1 of 3 intracranial components = increase in ICP Normal ICP 0 15 mmHg Foramen Magnum C1 atlas C2 axis (+) Projectile vomiting = increase ICP Observe for 24 - 48 hrs CSF cushions the brain, shock absorber Obstruction of flow of CSF = increase ICP Hydrocephalus posteriorly due to closure of posterior fontanel CVA partial/ total obstruction of blood supply

INCREASED ICP increase ICP is due to increase in 1 of the Intra Cranial components.
Predisposing factors: 1.) Head injury 2.) Tumor 3.) Localized abscess 4.) Hemorrhage (stroke) 5.) Cerebral edema 6.) Hydrocephalus 7.) Inflammatory conditions - Meningitis, encephalitis B. S&Sx change in VS = always late symptoms Earliest Sx: a.) Change or decrease LOC Restlessness to confusion Wide pulse pressure: Increased ICP - Disorientation to lethargy Narrow pp: Cardiac disorder, shock - Stupor to coma Late sign change in V/S 1. BP increase (systolic increase, diastole- same) 2. Widening pulse pressure Normal adult BP 120/80 120 80 = 40 (normal pulse pressure) Increase ICP = BP 140/80 = 140 80= 60 PP (wide) 3. RR is decreased (Cheyne-Stokes = bet period of apnea or hyperpnea with periods of apnea) 4. Temp increase Increased ICP: Increase BP Shock decrease BP Decrease HR Increase HR CUSHINGS EFFECT Decrease RR Increase RR Increase Temp Decrease temp b.) Headache Projectile vomiting Papilledima (edema of optic disk outer surface of retina) Decorticate (abnormal flexion) = Damage to cortico spinal tract / Decerebrate (abnormal extension) = Damage to upper brain stem-pons/ c.) Uncal herniation unilateral dilation of pupil. (Bilateral dilation of pupil tentorial herniation.) d.) Possible seizure.

Nursing priority: 1.) Maintain patent a/w & adequate ventilation a. Prevention of hypoxia (decrease tissue oxygenation) & hypercarbia (increase in CO2 retention). Hypoxia cerebral edema - increase ICP Hypoxia inadequate tissue oxygenation Late symptoms of hypoxia B bradycardia E extreme restlessness D dyspnea C cyanosis Early symptoms R restlessness A agitation T tachycardia Increase CO2 retention/ hypercarbia cerebral vasodilatation = increase ICP Most powerful respiratory stimulant increase in CO2 Hyperventilate decrease CO2 excrete CO2 Respiratory Distress Syndrome (RDS) decrease Oxygen Suctioning 10-15 seconds, max 15 seconds. Suction upon removal of suction cap. Ambu bag pump upon inspiration c. Assist in mechanical ventilation 1. Maintain patent a/w 2. Monitor VS & I&O 3. Elevate head of bed 30 45 degrees angle neck in neutral position unless contra indicated to promote venous drainage 4. Limit fluid intake 1,200 1,500 ml/day (FORCE FLUID means:Increase fluid intake/day 2,000 3,000 ml/day)- not for inc ICP. 5. Prevent complications of immobility 6. Prevent increase ICP by: a. Maintain quiet & comfy environment b. Avoid use of restraints lead to fractures c. Siderails up d. Instruct patient to avoid the ff: -Valsalva maneuver or bearing down, avoid straining of stool (give laxatives/ stool softener Dulcolax/ Duphalac) - Excessive cough antitussive Dextrometorpham -Excessive vomiting anti emetic (Plasil Phil only)/ Phenergan - Lifting of heavy objects - Bending & stooping e. Avoid clustering of nursing activities 7. Administer meds as ordered: 1.) Osmotic diuretic Mannitol./Osmitrol promotes cerebral diuresis by decompressing brain tissue Nursing considerations: Mannitol 1. Monitor BP SE of hypotension 2. Monitor I&O every hr. report if < 30cc out put 3. Administer via side drip 4. Regulate fast drip to prevent formation of crystals or precipitate 2.) Loop diuretic - Lasix (Furosemide) Nursing Mgt: Lasix Same as Mannitol except - Lasix is given via IV push (expect urine after 10-15mins) should be in the morning. If given at 7am. Pt will urinate at 7:15 Immediate effect of Lasix within 15 minutes. Max effect 6 hrs due (7am 1pm)

S/E of Lasix

Hypokalemia (normal K-3.5 5.5 meg/L)


1. 2. 3. S&Sx Weakness & fatigue Constipation (+) U wave in ECG tracing

Nursing Mgt: 1.) Administer K supplements ex Kalium Durule, K chloride Potassium Rich food: ABCs of K Vegetables Fruits A - asparagus A apple B broccoli (highest) B banana green C carrots C cantalope/ melon O orange (highest) for digitalis toxicity also. Vit A squash, carrots yellow vegetables & fruits, spinach, chesa Iron raisins, Food appropriate for toddler spaghetti! Not milk increase bronchial secretions Dont give grapes may choke S/E of Lasix: 1.) Hypokalemia 2.) Hypocalcemia (Normal level Ca = 8.5 11mg/100ml) or Tetany: S&Sx weakness Paresthesia (+) Trousseau sign pathognomonic or carpopedal spasm. Put bp cuff on arm=hand spasm. (+) Chevosteks sign Arrhythmia Laryngospasm Administer Ca gluconate IV slowly

Ca gluconate toxicity: Sx seizure administer Mg SO4


Mg SO4 toxcicity administer Ca gluconate B BP decrease U urine output decrease R RR decrease P patellar reflexes absent 3.) Hyponatremia Normal Na level = 135 145 meg/L S/Sx Hypotension Signs of Dehydration: dry skin, poor skin turgor, gen body malaise. Early signs Adult: thirst and agitation / Child: tachycardia Mgt: force fluid Administer isotonic fluid sol 4.) Hyperglycemia increase blood sugar level P polyuria P polyphagia P polydipsia Nsg Mgt: a. Monitor FBS (N=80 120 mg/dl) 5.) Hyperurecemia increase serum uric acid. Tophi- urate crystals in joint.

Gouty arthritis
Cool moist skin Sx joint pain & swelling usually at great toe.

kidney stones- renal colic (pain)

Nsg Mgt of Gouty Arthritis a.) Cheese (not sardines, anchovies, organ meat) (Not good if pt taking MAO) b.) Force fluid c.) Administer meds Allopurinol/ Zyloprim decrease uric acid production drug of choice for gout Colchicene excretes uric acid. Acute gout drug of choice. Kidney stones renal colic (pain). Cool moist skin Mgt: 1.) Force fluid 2.) Meds narcotic analgesic Morphine SO4 SE of Morphine SO4 toxicity Respiratory depression (check RR 1st) Antidote for morphine SO4 toxicity Narcan (NALOXONE) Naloxone toxicity tremors Increase ICP meds: 3.) Corticosteroids - Dexamethsone decrease cerebral edema (Decadrone) 4.) Mild analgesic codeine SO4. For headache. 5.) Anti consultants Dilantin (Phenytoin) Question: Increase ICP what is the immediate nsg action? a. Administer Mannitol as ordered b. Elevate head 30 45 degrees c. Restrict fluid d. Avoid use of restraints Nsg Priority ABC & safety

Pt suffering from epiglotitis. What is nsg priority? a. Administer steroids least priority b. Assist in ET temp, a/w c. Assist in tracheotomy permanent (Answer) d. Apply warm moist pack? Least priority Rationale: Wont need to pass larynx due to larynx is inflamed. ET cant pass. Need tracheostomy only Magic 2s of drug monitoring Drug D digoxin L - lithium A aminophylline D Dilantin A acetaminophen N range .5 1.5 meq/L .6 1.2 meq/L 10 19 mg/100ml 10 -19 mg/100 ml 10 30 mg/100ml Toxicity 2 2 20 20 200 Classification cardiac glycosides antimanic bronchodilator anticonvulsant narcotic analgesic Indication CHF bipolar COPD seizures osteoarthritis

Digitalis increase cardiac contraction = increase CO


Nursing Mgt 1. Check PR, HR (if HR below 60bpm, dont giveDigoxin) Digitalis toxicity antidote - Digivine a. Anorexia -initial sx. b. n/v GIT c. Diarrhea d. Confusion e. Photophobia f. Changes in color perception yellow spots

(Ok to give to pts with renal failure. Digoxin is metabolized in liver not in kidney.)

L lithium (lithane) decrease levels of norepinephrine, serotonine, acetylcholine


Antimanic agent Lithium toxicity S/Sx Anorexia n/s Diarrhea Dehydration force fluid, maintain Na intake 4 10g daily Hypothyroidism (CRETINISM the only endocrine disorder that can lead to mental retardation)

a.) b.) c.) d.) e.)

A aminophyline (theophylline) dilates bronchioles.


Take bp before giving aminophylline. S/Sx : Aminophylline toxicity: 1. Tachycardia 2. Hyperactivity restlessness, agitation, tremors Question: Avoid giving food with Aminophylline Cheese/butter food rich in tyramine, avoided only if pt is given MAOI Beer/ wine Hot chocolate & tea caffeine CNS stimulant tachycardia Organ meat/ box cereals anti parkinsonian

a. b. c. d.

MAOI antidepressant m AR plan n AR dil can lead to CVA or hypertensive crisis p AR nate 3 4 weeks - before MAOI will take effect Anti Parkinsonian agents Vit B6 Pyridoxine reverses effect of Levodopa

D dilatin (Phenytoin) anti convulsant/seizure


Nursing Mgt: 1. Mixed with plain NSS or .9 NaCl to prevent formation of crystals or precipitate - Do sandwich method - Give NSS then Dilantin, then NSS! 2. Instruct the pt to avoid alcohol bec alcohol + dilantin can lead to severe CNS depression

Dilantin toxicity: S/Sx: G gingival hyperplasia swollen gums i. Oral hygiene soft toothbrush ii. Massage gums H hairy tongue A - ataxia N nystagmus abnormal movement of eyeballs A acetaminophen/ Tylenol non-opoid analgesic & antipyretic febrile pts Acetaminophen toxicity : 1. Hepato toxicity 2. Monitor liver enzymes SGPT (ALT) Serum Glutamic Piruvate Tyranase SGOT- Serum Glutamic Acetate Tyranase 3. Monitor BUN (10 20) Crea (.8-1) Acetaminophen toxicity can lead to hypoglycemia T tremors, Tachycardia I irritability R restlessness E extreme fatigue D depression (nightmares) , Diaphoresis

Antidote for acetaminophen toxicity Acetylcesteine = causes outporing of secretions. Suction. Prepare suctioning apparatus. Question: The following are symptoms of hypoglycemia except: a. Nightmares b. Extreme thirst hyperglycemia symptoms c. Weakness d. Diaphoresis

PARKINSONS DSE (parkinsonism) - chronic, progressive disease of CNS char by degeneration of dopamine
producing cells in substancia nigra at mid brain & basal ganglia - Palliative, Supportive Function of dopamine: controls gross voluntary motors. Predisposing Factors: 1. Poisoning (lead & carbon monoxide). Antidote for lead = Calcium EDTA 2. Hypoxia 3. Arteriosclerosis 4. Encephalitis High doses of the ff: a. Reserpine (serpasil) anti HPN, SE 1.) depression - suicidal 2.) breast cancer b. Methyldopa (aldomet) - promote safety c. Haloperidol (Haldol)- anti psychotic d. Phenothiazide - anti psychotic SE of anti psychotic drugs Extra Pyramidal Symptom Over meds of anti psychotic drugs neuroleptic malignant syndrome char by tremors (severe) S/Sx: Parkinsonism 1. Pill rolling tremors of extremities early sign 2. Bradykinesia slow movement 3. Over fatigue 4. Rigidity (cogwheel type) a. Stooped posture b. Shuffling most common c. Propulsive gait 5. Mask like facial expression with decrease blinking eyes 6. Monotone speech 7. Difficulty rising from sitting position 8. Mood labilety always depressed suicide Nsg priority: Promote safety 9. Increase salivation drooling type 10. Autonomic signs: - Increase sweating - Increase lacrimation - Seborrhea (increase sebaceous gland) - Constipation - Decrease sexual activity Nsg Mgt 1.) Anti parkinsonian agents - Levodopa (L-Dopa), Carbidopa (Sinemet), Amantadine Hcl (Symmetrel) Mechanism of action Increase levels of dopa relieving tremors & bradykinesia S/E of anti parkinsonian - Anorexia - n/v - Confusion - Orthostatic hypotension - Hallucination - Arrhythmia Contraindication: 1. Narrow angled closure glaucoma 2. Pt taking MAOI (Parnate, Marplan, Nardil)

Nsg Mgt when giving anti-parkinsonian 1. Take with meals to decrease GIT irritation 2. Inform pt urine/ stool may be darkened 3. Instruct pt- dont take food Vit B6 (Pyridoxine) cereals, organ meats, green leafy veg - Cause B6 reverses therapeutic effects of levodopa Give INH (Isoniazide-Isonicotene acid hydrazide.) SE-Peripheral neuritis. 2.) Anti cholinergic agents relieves tremors Artane mech inhibits acetylcholine Cogentin action , S/E - SNS 3.) Antihistamine Diphenhydramine Hcl (Benadryl) take at bedtime S/E: adult drowsiness, avoid driving & operating heavy equipt. Take at bedtime. Child hyperactivity CNS excitement for kids. 4.) Dopamine agonist Bromotriptine Hcl (Parlodel) respiratory depression. Monitor RR. Nsg Mgt Parkinson 1.) Maintain siderails 2.) Prevent complications of immobility - Turn pt every 2h Turn pt every 1 h elderly 3.) Assist in passive ROM exercises to prevent contractures 4.) Maintain good nutrition CHON in am CHON in pm to induce sleep due Tryptopan Amino Acid 5.) Increase fluid in take, high fiber diet to prevent constipation 6.) Assist in surgery Sterotaxic Thalamotomy Complications in sterotaxic thalmotomy- 1.) Subarachnoid hemorrhage 2.) aneurism 3.) encephalitis

MULTIPLE SCLEROSIS (MS)


Chronic intermittent disorder of CNS white patches of demyelenation in brain & spinal cord. - Remission & exacerbation - Common women, 15 35 yo cause unknown Predisposing factor: 1. Slow growing virus 2. Autoimmune (supportive & palliative treatment only) Normal Resident Antibodies: Ig G can pass placenta passive immunity. Short acting. Ig A body secretions saliva, tears, colostrums, sweat Ig M acute inflammation Ig E allergic reactions IgD chronic inflammation S & Sx of MS: (everything down) 1. Visual disturbances a. Blurring of vision b. Diplopia/ double vision c. Scotomas (blind spots) initial sx 2. Impaired sensation to touch, pain, pressure, heat, cold a. Numbness b. Tingling c. Paresthesia 3. Mood swings euphoria (sense of elation ) 4. Impaired motor function: a. Weakness b. Spasiticity tigas c. Paralysis major problem 5. Impaired cerebellar function

10

Triad Sx of MS I intentional tremors N nystagmus abnormal rotation of eyes Charcots triad A Ataxia & Scanning speech 6. Urinary retention or incontinence 7. Constipation 8. Decrease sexual ability Dx MS 1. CSF analysis thru lumbar puncture - Reveals increase CHON & IgG 2. MRI reveals site & extent of demyelination 3. Lhermittes response is (+). Introduce electricity at the back. Theres spasm & paralysis at spinal cord. Nsg Mgt MS - Supportive mgt 1.) Meds a. Acute exacerbation ACTH adenocorticotopic Steroids to reduce edema at the site of demyelination to prevent paralysis Spinal Cord Injury Administer drug to prevent paralysis due to edema a. Give ACTH steroids b. Baclopen (Lioresol) or Dantrolene Na (Dantrium) To decrease muscle spasticity c. Interferone to alter immune response d. Immunosuppresants 2. Maintain siderails 3. Assist passive ROMexercises promote proper body alignment 4. Prevent complications of immobility 5. Encourage fluid intake & increase fiber diet to prevent constipation 6. Provide catheterization due urinary retention 7. Give diuretics Urinary incontinence give Prophantheline bromide (probanthene) Antispasmodic anti cholinergic 8. Give stress reducing activity. Deep breathing exercises, biofeedback, yoga techniques. 9. Provide acid-ash diet to acidify urine & prevent bacteria multiplication Grape, Cranberry, Orange juice, Vit C

MYASTHENIA GRAVIS (MG) disturbance in transmission of impulses from nerve to muscle cell at neuro muscular
junction. Common in Women, 20 40 yo, unknown cause or idiopathic Autoimmune release of cholenesterase enzyme Cholinesterase destroys ACH (acetylcholine) = Decrease acetylcholine Descending muscle weakness (Ascending muscle weakness Guillain Barre Syndrome) Nsg priority: 1) a/w 2) aspiration 3) immobility S/ Sx: 1.) Ptosis drooping of upper lid ( initial sign) Check Palpebral fissure opening of upper & lower lids = to know if (+) of MG. 2.) Diplopia double vision 3.) Mask like facial expression 4.) Dysphagia risk for aspiration! 5.) Weakening of laryngeal muscles hoarseness of voice 6.) Resp muscle weakness lead respiratory arrest. Prepare at bedside tracheostomy set 7.) Extreme muscle weakness during activity especially in the morning.

11

Dx test 1. Tensilon test (Edrophonium Hcl) temporarily strengthens muscles for 5 10 mins. Short term- cholinergic. PNS effect. Nsg Mgt 1. Maintain patent a/w & adequate vent by: a.) Assist in mechanical vent attach to ventilator b.) Monitor pulmonary function test. Decrease vital lung capacity. 2. Monitor VS, I&O neuro check, muscle strength or motor grading scale (4/5, 5/5, etc) 3. Siderails 4. Prevent complications of immobility. Adult-every 2 hrs. Elderly- every 1 hr. 5. NGT feeding Administer meds a.) Cholinergics or anticholinesterase agents Mestinon (Pyridostigmine) Neostignine (prostigmin) Long term - Increase acetylcholine s/e PNS b.) Corticosteroids to suppress immune resp Decadron (dexamethasone) Monitor for 2 types of Crisis: Myastinic crisis A cause 1. Under medication 2. Stress 3. Infection B S&Sx 1. Unable to see Ptosis & diplopia 2. Dysphagia- unable to swallow. 3. Unable to breath C Mgt adm cholinergic agents

Cholinergic crisis Cause: 1 over meds S/Sx - PNS n/v, diarrhea, hypotension, meiosis, facial muscle twitching, abdominal cramps

Mgt. adm anti-cholinergic - Atropine SO4 - SNS dry mouth 7. Assist in surgical proc thymectomy. Removal of thymus gland. Thymus secretes auto immune antibody. 8. Assist in plasmaparesis filter blood 9. Prevent complication respiratory arrest Prepare tracheostomy set at bedside.

GBS Guillain Barre Syndrome


- Disorder of CNS - Bilateral symmetrical polyneuritis - Ascending paralysis Cause unknown, idiopathic - Auto immune - r/t antecedent viral infection - Immunizations S&Sx Initial : 1. Clumsiness 2. Ascending muscle weakness lead to paralysis 3. Dysphagia 4. Decrease or diminished DTR (deep tendon reflexes) - Paralysis 5. Alternate HPN to hypotension lead to arrhythmia - complication 6. Autonomic changes increase sweating, increase salivation. Increase lacrimation Constipation Dx most important: CSF analysis thru lumbar puncture reveals increase in : IgG & CHON (same with MS)

12

Nsg Mgt 1. Maintain patent a/w & adequate vent a. Assist in mechanical vent b. Monitor pulmonary function test 2. Monitor vs., I&O neuro check, ECG tracing due to arrhythmia 3. Siderails 4. Prevent compl immobility 5. Assist in passive ROM exercises 6. Institute NGT feeding due dysphagia 7. Adm meds (GBS) as ordered: 1. Anti cholinergic atropine SO4 2. Corticosteroids to suppress immune response 3. Anti arrhythmic agents a.) Lidocaine /Xylocaine SE confusion = VTach b.) Bretyllium c.) Quinines/Quinidine anti malarial agent. Give with meals. - Toxic effect cinchonism Quinidine toxicity S/E anorexia, n/v, headache, vertigo, visual disturbances 8. Assist in plasmaparesis (MG. GBS) 9. Prevent comp arrhythmias, respiratory arrest Prepare tracheostomy set at bedside.

INFL CONDITONS OF BRAIN Meninges 3-fold membrane cover brain & spinal cord Fx: Protection & support Nourishment Blood supply 3 layers 1. Duramater sub dural space 2. Arachmoid matter 3. Pia matter sub arachnoid space

where CSF flows L3 & L4. Site for lumbar puncture.

MENINGITIS inflammation of meningitis & spinal cord


Etiology Meningococcus Pneumococcus Hemophilous influenza child Streptococcus adult meningitis MOT direct transmission via droplet nuclei S&Sx - Stiff neck or nuchal rigidity (initial sign) - Headache - Projectile vomiting due to increase ICP - Photophobia - Fever chills, anorexia - Gen body malaise - Wt loss - Decorticate/decerebration abnormal posturing - Possible seizure Sx of meningeal irritation nuchal rigidity or stiffness Opisthotonus- rigid arching of back Pathognomonic sign (+) Kernigs & Brudzinski sign Leg pain neck pain

13

Dx: 1. Lumbar puncture lumbar/ spinal tap use of hallow spinal needle sub arachnoid space L3 & L4 or L4 & L5 Aspirate CSF for lumbar puncture. Nsg Mgt for lumbar puncture invasive 1. Consent / explain procedure to pt - RN dx procedure (lab) - MD operation procedure 2. Empty bladder, bowel promote comfort 3. Arch back to clearly visualize L3, L4 Nsg Ngt post lumbar 1. Flat on bed 12 24 h to prevent spinal headache & leak of CSF 2. Force fluid 3. Check punctured site for drainage, discoloration & leakage to tissue 4. Assess for movement & sensation of extremeties Result 1. CSF analysis:

a. increase CHON & WBC Content of CSF: Chon, wbc, glucose b. Decrease glucose Confirms meningitis c. increase CSF opening pressure N 50 160 mmHg d. (+) Culture microorganism 2. Complete blood count CBC reveals increase WBC Mgt: 1. Adm meds a.) Broad-spectrum antibiotic penicillin S/E 1. GIT irritation take with food 2. Hepatotoxicity, nephrotoxcicity 3. Allergic reaction 4. Super infection alteration in normal bacterial flora - N flora throat streptococcus - N flora intestine e coli Sx of superinfection of penicillin = diarrhea b.) Antipyretic c.) Mild analgesic 2. Strict resp isolation 24h after start of antibiotic therapy A Cushings synd reverse isolation - due to increased corticosteroid in body. B Aplastic anemia reverse isolation - due to bone marrow depression. C Cancer anytype reverse isolation immunocompromised. D Post liver transplant reverse isolation takes steroids lifetime. E Prolonged use steroids reverse isolation F Meningitis strict respiratory isolation safe after 24h of antibiotic therapy G Asthma not to be isolated Comfy & dark room due to photophobia & seizure Prevent complications of immobility Maintain F & E balance Monitor vs, I&O , neuro check Provide client health teaching & discharge plan a. Nutrition increase cal & CHO, CHON-for tissue repair. Small freq feeding b. Prevent complication hydrocephalus, hearing loss or nerve deafness. 8. Prevent seizure. Where to bring 2 yo post meningitis - Audiologist due to damage to hearing- post repair myelomeningocele - Urologist -Damage to sacral area spina bifida controls urination 9. Rehab for neurological deficit. Can lead to mental retardation or a delay in psychomotor development. 3. 4. 5. 6. 7.

14

CEREBRO VASCULAR ACCIDENT stroke, brain attack or cerebral thrombosis, apoplexy


Partial or complete disruption in the brains blood supply 2 largest & common artery in stroke Middle cerebral artery Internal carotid artery Common to male 2 3x high risk

Predisposing factor: 1. Thrombosis clot (attached) 2. Embolism dislodged clot pulmo embolism S/Sx: pulmo embolism Sudden sharp chest pain Unexplained dyspnea, SOB Tachycardia, palpitations, diaphoresis & mild restlessness S/Sx: cerebral embolism Headache, disorientation, confusion & decrease in LOC Femur fracture complications: fat embolism most feared complication w/in 24hrs Yellow bone marrow produces fat cells at meduallary cavity of long bone Red bone marrow provides WBC, platelets, RBC found at epiphisis 2.) Hemorrhage 3.) Compartment syndrome compression of nerves/ arteries Risk factors of CVA: HPN, DM, MI, artherosclerosis, valvular heart dse - Post heart surgery mitral valve replacement Lifestyle: 1. Smoking nicotine potent vasoconstrictor 2. Sedentary lifestyle 3. Hyperlipidemia genetic 4. Prolonged use of oral contraceptives - Macro pill has large amt estrogen - Mini pill has large amt of progestin - Promote lipolysis (breakdown of lipids/fats) artherosclerosis HPN - stroke 5. Type A personality a. Deadline driven person b. 2 5 things at the same time c. Guilty when not dong anything 6. Diet increase saturated fats 7. Emotional & physical stress 8. Obesity

S & Sx 1. TIA- warning signs of impending stroke attacks - Headache (initial sx), dizziness/ vertigo, numbness, tinnitus, visual & speech disturbances, paresis or plegia (monoplegia 1 extreme) Increase ICP 2. Stroke in evolution progression of S & Sx of stroke 3. Complete stroke resolution of stroke a.) Headache b.) Cheyne-Stokes Resp c.) Anorexia, n/v d.) Dysphagia e.) Increase BP f.) (+) Kernigs & Brudzinski sx of hemorrhagic stroke g.) Focal & neurological deficit 1. Phlegia 2. Dysarthria inability to vocalize, articulate words 3. Aphasia 4. Agraphia diff writing 5. Alesia diff reading 6. Homoninous hemianopsia loss of half of field of vision

15

Left sided hemianopsia approach Right side of pt the unaffected side Dx 1. CT Scan reveals brain lesion 2. Cerebral arteriography site & extent of mal occlusion - Invasive procedure due to inject dye - Allergy test All graphy invasive due to iodine dye Post 1.) Force fluid to excrete dye is nephrotoxic 2.) Check peripheral pulses - distal Nsg Mgt 1. Maintain patent a/w & adequate vent - Assist mechanical ventilation - Administer O2 2. Restrict fluids prevent cerebral edema 3. Elevate head of bed 30-45 degrees angle. Avoid valsalva maneuver. 4. Monitor vs., I&O, neuro check 5. Prevent compl of immobility by: a. Turn client q2h Elderly q1h - To prevent decubitus ulcer - To prevent hypostatic pneumonia after prolonged immobility. b. Egg crate mattress or H2O bed c. Sand bag or foot board- prevent foot drop 6. NGT feeding if pt cant swallow 7. Passive ROM exercise q4h 8. Alternative means of communication - Non-verbal cues - Magic slate. Not paper and pen. Tiring for pt. - (+) To hemianopsia approach on unaffected side 9. Meds Osmotic diuretics Mannitol Loop diuretics Lasix/ Furosemide Corticosteroids dextamethazone Mild analgesic Thrombolytic/ fibrolitic agents tunaw clot. SE-Urticaria, pruritus-caused by foreign subs. Streptokinase Urokinase Tissue plasminogen activating Monitor bleeding time Anticoagulants Heparin & Coumadin sabay Coumadin will take effect after 3 days Heparin monitor PTT partial thromboplastin time if prolonged bleeding give Protamine SO4- antidote. Coumadin Long term. monitor PT prothrombin time if prolonged- bleeding give Vit K Aquamephyton- antidote. Antiplatelet PASA aspirin paraanemo aspirin, dont give to dengue, ulcer, and unknown headache. Health Teaching 1. Avoidance modifiable lifestyle - Diet, smoking 2. Dietary modification - Avoid caffeine, decrease Na & saturated fats Complications: Subarachnoid hemorrhage Rehab for focal neurological deficit physical therapy 1. Mental retardation 2. Delay in psychomotor development

16

CONVULSIVE Disorder (CONVULSIONS)- disorder of the CNS char. by paroxysmal seizures with or without loss of
consciousness, abnormal motor activity, alteration in sensation & perception & change in behavior. Can you outgrow febrile seizure? Febrile seizure Normal if < 5 yo Pathologic if > 5 yo Difference between: Seizure- 1st convulsive attack Epilepsy 2nd and with history of seizure

Predisposing Factor Head injury due birth trauma Toxicity of carbon monoxide Brain tumor Genetics Nutritional & metabolic deficit Physical stress Sudden withdrawal to anticonvulsants will bring about status epilepticus Status epilepticus drug of choice: Diazepam & glucose S & Sx I. Generalized Seizure a.) Grand mal / tonic clonic seizures With or without aura warning symptoms of impending seizure attack- Epigastric pain- associated with olfactory, tactile, visual, auditory sensory experience - Epileptic cry fall - Loss of consciousness 3 5 min - Tonic clonic contractions - Direct symmetrical extension of extremities-TONIC. Contractions-CLONIC - Post ictal sleep -state of lethargy or drowsiness - unresponding sleep after tonic clonic b.) Petimal seizure (same as daydreaming!) or absent seizure. - Blank stare - Decrease blinking eye - Twitching of mouth - Loss of consciousness 5 10 secs (quick & short) II. Localized/partial seizure a.) Jacksonian seizure or focal seizure tingling/jerky movement of index finger/thumb & spreads to shoulder & 1 sideof the body with janksonian march b.) Psychomotor/ focal motor - seizure -Automatism stereotype repetitive & non-purposive behavior - Clouding of consciousness not in control with environment - Mild hallucinatory sensory experience HALLUCINATIONS Auditory schitzo paranoid type Visual korsakoffs psychosis chronic alcoholism Tactile addict substance abuse

1. 2. 3.

III. Status epilecticus continuous, uninterrupted seizure activity, if untreated, lead to hyperprexia coma death Seizure: inc electrical firing in brain=increased metabolic activity in brain=brain using glucose and O2=dec glucose, dec O2. Tx:Diazepam (drug of choice), glucose Dx-Convulsion- get health history! 1. CT scan brain lesion 2. EEG electroencephalography - Hyperactivity brain waves Nsg Mgt Priority Airway & safety 1. Maintain patent a/w & promote safety Before seizure: 1. Remove blunt/sharp objects 2. Loosen clothing

17

3. 4. 5. 6. 7. 8. a.

Avoid restraints Maintain siderails Turn head to side to prevent aspiration Tongue guard or mouth piece to prevent biting of tongue-BEFORE SEIZURE ONLY! Can use spoon at home. Avoid precipitating stimulus bright glaring lights & noises Administer meds Dilantin (Phenytoin) ( toxicity level 20 )

SE Ginguial hyperplasia H-hairy tongue A-ataxia N-nystagmus A-acetaminophen- febrile pt Mix with NSS - Dont give alcohol lead to CNS depression b. (Tegretol) Carbamasene- given also to Trigeminal Neuralgia. SE: arrythmia c. Phenobarbital (Luminal)- SE: hallucinations 2. Institute seizure & safety precaution. Post seizure: Administer O2. Suction apparatus ready at bedside 3. Monitor onset & duration - Type of seizure - Duration of post ictal sleep. The longer the duration of post ictal sleep, the higher chance of having status epilepticus! 4. Assist in surgical procedure. Cortical resection 5. Complications: Subarachnoid hemorrhage and encephalitis Question: 1 yo grand mal immediate nursing action = a/w & safety a. Mouthpiece 1 yr old little teeth only b. Adm o2 inhalation post! c. Give pillow safety (answer) d. Prepare suction Neurological assessment: 1. Comprehensive neuro exam 2. GCS - Glasgow coma scale obj measurement of LOC or quick neuro check 3 components of ECS M motor 6 V verbal resp 5 E eye opening 4 15 15 14 conscious 13 11 lethargy 10 8 stupor 7 coma 3 deep coma lowest score Survey of mental status & speech (Comprehensice Neuro Exam) 1.) LOC & test of memory 2.) Levels of orientation 3.) CN assessment 4.) Motor assessment 5.) Sensory assessment 6.) Cerebral test Romhberg, finger to nose 7.) DTR 8.) Autonomics Levels of consciousness (LOC) 1. Conscious (conscious) awake levels of wakefulness 2. Lethargy (lethargic) drowsy, sleepy, obtunded

18

Stupor (stuporous) awakened by vigorous stimulation Pt has gen body weakness, decrease body reflex 4. Coma (Comatose) light (+) all forms of painful stimulations Deep (-) to painful stimulation Question: Describe a conscious pt ? a. Alert not all pt are alert & oriented to time & place b. Coherent c. Awake- answer d. Aware 3. Different types of pain stimulation - Dont prick 1. Deep sternal stimulation/ pressure 3x fist knuckle With response light coma Without response deep coma 2. Pressure on great toe 3x 3. Orbital pressure pressure on orbits only below eye 4. Corneal reflex/ blinking reflex Wisp of cotton used to illicit blinking reflex among conscious patients Instill 1-drop saline solution unconscious pt if (-) response pt is in deep coma 5. Test of memory considered educational background a.) Short term memory - What did you eat for breakfast? Damage to temporal lobe (+) antero grade amnesia b.) Long term memory (+) Retrograde amnesia damage to limbic system 6. Levels of orientation Time Place Person Graphesthesia- can identify numbers or letters written on palm with a blunt object. Agraphesthesia cant identify numbers or letters written on palm with a blunt object.

CN assessment:
I II III IV V VI VII VIII IX X XI XII Olfactory Optic Oculomotor Trocheal Trigeminal Abducens Facial Acustic/auditory Glassopharyngeal Vagus Spinal accessory Hypoglossal s s m m b m b s b b m m

smallest CN largest CN

longest CN

I. Olfactory dont use ammonia, alcohol, cologne irritating to mucosa use coffee, bar soap, vinegar, cigarette tar - Hyposmia decrease sensitivity to smell - Diposmia distorted sense of smell - Anosmia absence of sense of smell Either of 3 might indicate head injury damage to cribriform plate of ethmoid bone where olfactory cells are located or indicate inflammation condition sinusitis II optic- test of visual acuity Snellens chart central or distance vision Snellens E chart used for illiterate chart N 20/20 vision distance by w/c person can see letters- 20 ft Numerator distance to snellens chart Denominator distance the person can see the letters OD Rt eye 20/20 20/200 blindness cant read E biggest OS left eye 20/20 OU both eye 20/20

19

2. a. b. c. d.

Test of peripheral vision/ visual field Superiority Bitemporally Inferiorly Nasally

Common Disorders see page 85-87 for more info on glaucoma, etc. 1. Glaucoma Normal 12 21 mmHg pressure - Increase IOP - Loss of peripheral vision tunnel vision 2. Cataract opacity of lens - Loss of central vision, Blurring or hazy vision 3. Retinal detachment curtain veil like vision & floaters 4. Macular degeneration black spots III, IV, VI tested simultaneously - Innervates the movementt of extrinsic ocular muscle 6 cardinal gaze EOM Rt eye IO LR SR 3 4 EOM IV sup oblique VI lateral rectus Normal response PERRLA (isocoria equal pupil) Anisocoria unequal pupil Oculomotor 1. Raising of eyelid Ptosis 2. Controls pupil size 2 -3 cm or 1.5 2 mm V Trigeminal Largest consists of - ophthalmic, maxillary, mandibular Sensory controls sensation of the face, mucus membrane; teeth & cornea reflex Unconscious instill drop of saline solution Motor controls muscles of chewing/ muscles of mastication Trigeminal neuralgia diff chewing & swallowing extreme food temp is not recommended Question: Trigeminal neuralgia, RN should give a. Hot milk, butter, raisins b. Cereals c. Gelatin, toast, potato all correct but d. Potato, salad, gelatin salad easier to chew VI Facial: Sensory controls taste ant 2/3 of tongue test cotton applicator put sugar. -Put applicator with sugar to tip to tongue. -Start of taste insensitivity: Age group 40 yrs old Motor- controls muscles of facial expression, smile frown, raise eyebrow Damage Bells palsy facial paralysis Cause bells palsy pedia R/T forcep delivery Temporary only Most evident clinical sign of facial symmetry: Nasolabial folds VIII Acoustic/ vestibule cochlear (controls hearing) controls balance (kenesthesia or position sense) - Movement & orientation of body in space - Organ of Corti for hearing true sense organ of hearing SO MR N O S E left eye

20

Outer tympanic membrane, pinna, oricle (impacted cerumen), cerumen Middle hammer, anvil, stirrup or melleus, incus, staples. Mid otitis media Eustachean ear Inner ear- meniere dse, sensory hearing loss (research parts! & dse) Remove vestibule menieres dse disease inner ear

Archimedes law buoyancy (pregnancy fetus) Daltons law partial pressure of gases Inertia law of motion (dizziness, vertigo) 1.) Pt with multiple stab wound - chest - Movement of air in & out of lungs is carried by what principle? - Diffusion Daltons law 2.) Pregnant check up ultrasound reveals fetus is carried by amniotic fluid - Archimedes 3.) Severe vertigo due- Inertia Test for acoustic nerve: - Repeat words uttered IX Glossopharyngeal controls taste posterior 1/3 of tongue X Vagus controls gag reflex Test 9 10 Pt say ah check uvula should be midline Damage cerebral hemisphere is L or R Gag reflex place tongue depression post part of tongue Dont touch uvula XI Spinal Accessory - controls sternocleidomastoid (neck) & trapezius (shoulders and back) - Shrug shoulders, put pressure. Pt should resist pressure. Paresis or phlegia XII Hypoglossal controls movement of tongue say ah. Assess tongue position=midline L or R deviation - Push tongue against cheek - Short frenulum lingue Tongue tied bulol

ENDOCRINE Fx of endocrine ductless gland Main gland Pituitary gland located at base of brain of Stella Turcica Master gland of body Master clock of body Anterior pituitary gland adenohypophysis Posterior pituitary gland neurohypophysis Posterior pituitary: 1.) Oxytocin a.) Promotes uterine contraction preventing bleeding/ hemorrhage. - Give after placental delivery to prevent uterine atony. b.) Milk letdown reflex with help of prolactin. 2.) ADH antidiuretic hormone (vasopressin) -Prevents urination conserve H2O

Eric 21 21

A. DIABETIS INSIPIDUS (DI- dalas ihi) hyposecretion of ADH


Cause: idiopathic/ unknown Predisposing factor: 1. Pituitary surgery 2. Trauma/ head injury 3. Tumor 4. Inflammation * alcohol inhibits release of ADH

S & Sx: 1. Polyuria 2. Sx of dehydration - Excessive thirst (adult) - Agitation - Poor skin turgor - Dry mucus membrane 3. Weakness & fatigue 4. Hypotension if left untreated 5. Hypovolemic shock Anuria late sign hypovolemic shock (1st sx of dehydration in children-tachycardia)

Dx Proc: 1. Decrease urine specific gravity- concentrated urine N= 1.015 1.035 2. Serum Na = increase (N=135 -145 meq/L) Hypernatremia Mgt: 1. 2. 3. 4. Force fluid 2,000 3,000ml/day Administer IV fluid replacement as ordered Monitor VS, I&O Administer meds as ordered a.) Pitresin (vasopressin) IM 5. Prevent complications Most feared complication Hypovolemic shock

B.) SIADH - Syndrome of Inappropriate Anti-Diuretic Hormone


- Increase ADH - Idiopathic/ unknown Predisposing factor 1. Head injury 2. Related to Bronchogenic cancer or lung canerEarly Sign of Lung Ca - Cough 1. non productive 2. productive 3. Hyperplasia of Pit gland Increase size of organ S&Sx 1. 2. 3. 4. 5.

Fluid retention Increase BP HPN Edema Wt gain Danger of H2O intoxication Complications: 1. cerebral edema increase ICP 2. seizure

Dx Proc: 1. Urine specific gravity increase diluted urine 2. Hyponatremia Decreased Na

22

Nsg Mgt: 1. Restrict fluid 2. Administer meds as ordered eg. Diuretics: Loop and Osmotic 3. Monitorstrictly V/S, I&O, neuro check increase ICP 4. Weigh daily 5. Assess for presence edema 6. Provide meticulous skin care 7. Prevent complications increase ICP & seizures activity Anterior Pituitary Gland adeno 1. Growth hormone (GH) (Somatotropic hormone) Fx: Elongation of long bones Decrease GH dwarfism children Increase GH gigantism Increase GH acromegaly adult Puberty 9 yo 21 yo Epiphyseal plate closes at 21 yo Square face Square jaw Drug of choice in acromegaly: Ocreotide (Sandostatin) SE dizziness Somatostatin Hormone antagonizes the release of of GH Melanocytes stimulating hormone - MSH Skin pigmentation Prolactin/luteotrpic hormone/ lactogenic hormone - Promotes development of mammary gland (Oxytocin-Initiates milk letdown reflex) 4. Adrenocorticotropic hormone ACTH - Development & maturation of adrenal cortex 5. Luteinizing hormone produces progesterone. 6. FSH- produces estrogen 2. 3. PINEAL GLAND 1. Secretes Melatonin inhibits lutenizing hormone (LH) secretion THYROID GLAND (TG) Question: Normal physical finding on TG: a. With tenderness thyroid never tender b. With nodular consistency- answer c. Marked asymmetry only 1 TG d. Palpable upon swallowing - Normal TG never palpable unless with goiter

TG hormones: T3 - Triodothyronine - 3 molecules of iodine

T4 -Tetraiodothyronine/ Tyroxine - 4 molecules of iodine

Thyrocalcitonin FX antagonizes effects of parathormone

Metabolic hormone Increase metabolism brain inc cerebration, inc v/s Hypo T3 T4 - lethargy & memory impairment Hyper T3 T4 - agitation, restlessness, and hallucination 7. Increase VS, increase motility HYPOTHYROIDISM all decreased except wt & menstruation, loss of appetite but with wt gain menorrhagia increase in mens HYPERTHYROIDISM - Increase appetite wt loss, amenorrhea all v/s down, constipation

23

SIMPLE GOITER enlarged thyroid gland - iodine deficiency


Predisposing factors 1. Goiter belt area - Place far from sea no iodine. Seafoods rich in iodine 2. Mountainous area increase intake of goitrogenic foods (US: Midwest, NE, Salt Lake) Cabbage has progoitrin an anti thyroid agent with no iodine Example: Turnips (singkamas), radish, peas, strawberries, potato, beans, kamote, cassava (root crops), all nuts. 3. Goitrogenic drugs: Anti thyroid agents :(PTU) prephyl thiupil Lithium carbonate, Aspirin PASA Cobalt, Phenyl butasone Endemic goiter cause # 1 Sporadic goiter caused by #2 & 3 S & Sx enlarged TG Mild restlessness Mild dysphagia Dx Proc. 1. Thyroid scan reveals enlarged TG 2. Serum TSH increase (confirmatory) 3. Serum T3, T4 N or below N Nsg Mgt: 1. Administer meds a.) Iodine solution Logols solution or saturated sol of K iodide SSKI Nsg Mgt Lugols sol violet color 1. use straw prevent staining teeth 2. Prophylaxis 2 -3 drops Treatment 5 to 6 drops Use straw to prevernt staining of teeth 1. Lugols sol., 2. tetracycline 3. nitrofurantin (macrodantin)-urinary anticeptic-pyelonephritis. 4. Iron solution. B. Thyroid h / Agents 1. Levothyroxine (Synthroid) 2. Liothyronine (cytomel) 3. Thyroid extract

Nsg Mgt: for TH/agents 1. Monitor vs. HR due tachycardia & palpitation 2. Take it early AM SE insomnia 3. Monitor s/e Tachycardia, palpitations Signs of insomnia Hyperthyroidism restlessness agitation Heat intolerance HPN 3. Encourage increase intake iodine iodine is extracted from seaweeds (!) Seafood- highest iodine content oysters, clams, crabs, lobster Lowest iodine shrimps Iodized salt easily destroyed by heat take it raw not cooked Assist surgery- Sub total thyroidectomyComplication: 1. Tetany 2. laryngeal nerve damage 3.Hemorrhage-feeling of fullness at incision site.Check nape for wet blood. 4.Laryngeal spasm DOB, SOB trache set ready at bedside.

4.

24

2.)

HYPOTHYROIDISM decrease secretion of T3, T4 can lead to MI / Atherosclerosis

Adult myxedema Child- cretinism only endocrine dis lead to mental retardation Predisposing factor: 1. `Iatrogenic causes caused by surgery 2. Atrophy of TG due to: a. Irradiation b. Trauma c. Tumor, inflammation 3. Iodine def 4. Autoimmune Hashimoto disease

S&Sx everything decreased except wt gain & mens increase) Early signs weakness and fatigue Loss of appetite increased lypolysis breakdown of fats causing atherosclerosis = MI Wt gain Cold intolerance myxedema - coma Constipation Late Sx brittle hair/ nails Non pitting edema due increase accumulation of mucopolysacharide in SQ tissue -Myxedema Horseness voice Decrease libido Decrease VS hypotension bradycardia, bradypnea, and hypothermia Lethargy Memory impairment leading to psychosis-forgetfulness Menorrhagia Dx: 1. 2. 3. Serum T3 T4 decrease Serum cholesterol increase can lead to MI RA IU radio iodine uptake decrease

Nsg Mgt: 1. Monitor strictly V/S. I&O to determine presence of myxedema coma! Myxedema Coma - Severe form of hypothyroidism Hypotension, hypoventilation, bradycardia, bradypnea, hyponatremia, hypoglycemia, hypothermia Might lead to progressive stupor & coma Impt mgt for Myxedema coma 1. Assist mech vent priority a/w 2. Adm thyroid hormone 3. Adm IVF replacement force fluid Mgt myxedema coma 1. Monitor VS, I&O 2. Provide dietary intake low in calories due to wt gain 3. Skin care due to dry skin 4. Comfortable & warm environment due to cold intolerance 5. Administer IVF replacements 6. Force fluid 7. Administer meds take AM SE insomia. Monitor HR. Thyroid hormones Levothyroxine(Synthroid), Liothyronine (cytomel) Thyroid extracts 8. Health teaching & discharge plan a. Avoidance precipitating factors leading to myxedema coma: 1. Exposure to cold environment 2. Stress 3. Infection 4. Use of sedative, narcotics, anesthetics not allowed CNS depressants V/S already down

25

Complications: 9. Hypovolemic shock, myxedema coma 10. Hormonal replacement therapy - lifetime 11. Importance of follow up care

HYPERTHYROIDISM - Graves dse or thyrotoxicosis ( everything up except wt and mens)


-Increased T3 & T4 Predisposing factors: 1. Autoimmune disease release of long acting thyroid stimulator (LATS) Exopthalmos Enopthalmos severe dehydration depressed eye 2. Excessive iodine intake 3. Hyperplasia of TG S&Sx: 1. 2. 3. 4. 5. 6. 8. 7. 8. 9. Dx: 1. 2. 3. Serum T3 & T4 - increased Radio iodine uptake increase Thyroid scan reveals enlarged TG Increase in appetite hyperphagia wt loss due to increase metabolism Skin is moist - perspiration Heat intolerance Diarrhea increase motility All VS increase = HPN, tachycardia, tachypnea, hyperthermia CNS changes Irritability & agitation, restlessness, tremors, insomnia, hallucinations Goiter Exopthalmos pathognomonic sx Amenorrhea

Nsg Mgt: 1. Monitor VS & I & O determine presence of thyroid storm or most feared complication: Thyrotoxicosis 2. Administer meds a. Antithyroid agents 1. Prophylthiuracil (PTU) 2. Methymazole (Tapazole) Most toxic s/e agranulocytosis- fever, sore throat, leukocytosis=inc wbc: check cbc and throat swab culture Most feared complication : Thrombosis stroke CVS 3. 4. 5. 6. 7. 8. Diet increase calorie to correct wt loss Skin care Comfy & cool environment Maintain siderails- due agitation/restlessness Provide bilateral eye patch to prevent drying of eyes- exopthalmos Assist in surgery subtotal thyroidectomy

Nsg Mgt: pre-op Adm Lugols solution (SSKI) K iodide 9. To decrease vascularity of TG 10. To prevent bleeding & hemorrhage Mgt post op: Complication: 1. Watch out for signs of thyroid storm or thyrotoxicosis Triad signs of thyroidstorm; Tachycardia /palpitation Hyperthermia Agitation

a. b. c.

26

1. 2. 3.

Nsg Mgt Thyroid Storm: Monitor VS & neuro check Agitated might decrease LOC Antipyretic fever Tachycardia - blockers (-lol) Siderails agitated

Comp 2. Watch for inadvertent (accidental) removal of parathyroid gland Secretes Para hormone If removed, hypocalcemia - classic sign tetany 1. .(+) Trousseau sign/ 2. Chvostecks sign Nsg Mgt: Adm calcium gluconate slowly to prevent arrhythmia Ca gluconate toxicity antidote MgSO4 3. Laryngeal (voice box) nerve damage (accidental) Sx: hoarseness of voice ***Encourage pt to talk or speak post operatively asap to determine laryngeal nerve damage Notify physician! 4. Signs of bleeding post subtotal thyroidectomy - Feeling of fullness at incision site Nsg mgt: Check soiled dressing at nape area 5. Signs of laryngeal spasm a. DOB b. SOB Prepare at bedside tracheostomy 6. Hormonal replacement therapy - lifetime 7. Importance of follow up care (Liver cirrhosis bedside scissor if pt complaints of DOB)

(Cut cystachean tube to deflate balloon)

Parathyroid gland pair of small nodules located behind the TG 11. Secrets parathyroid hormone promotes Ca reabsorption Thyrocalcitonin antagonises secretion of parathyroid hormone 1. 2. Hypoparthroidism decrease of parathyroid hormone Hyperparathroidsm

HYPOPARATHYROIDISM decreased parathormone


Hypocalcemia (Or tetany) [If Ca decreases, phosphate increases] A. Predisposing, factors: 1. Following subtotal thyroidectomy 2. Atrophy of parathyroid gland due to a. Irradiation b. Trauma Hyperphosphatemia

27

S&Sx: 1. Acute tetany a. Tingling sensation b. Paresthesia c. Dysphagia d. Laryngospasm e. Bronchospasm Pathognomonic Sign of tetany: a. (+) Trousseaus or carpopedial spasm b. (+) Chvostecks sign f. Seizure g. Arrhythmia 2. most feared complication

Chronic tetany a. Loss of tooth enamel b. Photophobia & cataract formation c. GIT changes anorexia, n/v, general body malaise d. CNS changes memory impairment, irritability Serum calcium decrease (N 8.5 11 mg/100ml) Serum phosphate increase (N 2.5 4.5 mg/100ml) X-ray of long bone decrease bone density CT Scan reveals degeneration of basal ganglia

Dx: 1. 2. 3. 4.

Nsg Mgt: 1. Administration of meds: a.) Acute tetany Ca gluconate IV, slowly b.) Chronic tetany 1. Oral Ca supplements Ex. Ca gluconate Ca carbonate Ca lactate

Vit D (Cholecalceferol) Drug diet sunlight 7am 9am

Cholecalceferol

calcidiol

calcitriol

2. Phosphate binder Alumminum DH gel (ampho gel) SE constipation Antacid AAC MAD Aluminum containing acids Mg containing antacids Ex. Milk or magnesia Aluminum OH gel Diarrhea Constipation Maalox magnesium & aluminum - Less s/e 2. Avoid precipitating stimulus such as bright lights & noise: photophobia leading to seizure 3. Diet increase Ca & decrease phosphorus - Dont give milk due to increase phosphorus Good = anchovies increase Ca, decrease phosphorus + inc uric acid. Tuna & green turnips- Inc Ca. 4. Bedside tracheostomy set due to laryngospasm

28

5. Encourage to breath with paper bag in order to produce mild respiratory acidosis to promote increase ionized Ca levels 6. Most feared complication : Seizure & arrhythmia 7. Hormonal replacement therapy - lifetime 8. Important fallow up care

HYPERPARATHYROIDISM - increase parathormone. Complication: Renal failure


Hypercalcemia can lead to Hypophosphatemia

Bone dse Mineralization

kidney stones

Leading to bone fracture Ca 99% bones 1% serum blood Predisposing Factors: 1. Hyperplasia parathyroid gland (PTG) 2. Over compensation of PTG due to Vit D deficiency Children Rickets Vit D Adults Osteomalacia deficiency Sippys diet Vit D diet not good for pt with ulcer 2 -4 cups of milk & butter Karrels diet Vit D diet not good for pt with ulcer 6 cups of milk & whole cream Food rich in CHON eggnog combination of egg & milk S/Sx: Bone fracture 1. Bone pain (especially at back), bone fracture 2. Kidney stone a. Renal colic b. Cool moist skin 3. GIT changes anorexia, n/v, ulcerations 4. CNS involvement irritability, memory impairment

Dx Proc: 1. Serum Ca increase 2. Serum phosphorus decreases 3. X-ray long bones reveals bone demineralization Nsg Mgt: Kidney Stone 1. 2. 3. 4. 5. 6. Force fluids 2,000 3,000/day or 2-3L/day Isotonic solution Warm sitz bath for comfort Strain all urine with gauze pad Acid ash diet cranberry, plum, grapefruit, vit C, calamansi to acidify urine Adm meds a. Narcotic analgesic Morphine SO4, Demerol (Meperidine Hcl) S/E resp depression. Monitor RR) Narcan/ Naloxone antidote Naloxone toxicity tremors Siderails Assist in ambulation

7. 8.

29

9. Diet low in Ca, increase phosphorus lean meat 10. Prevent complication Most feared renal failure 11. Assist surgical procedure parathyroidectomy 12. Impt ff up care 13. Hormonal replacement- lifetime ADRENAL GLAND 12. Atop of @ kidney 13. 2 parts Adrenal cortex outermost layer Adrenal medulla - innermost layer 14. Secrets cathecolamines a.) Epinephrine / Norephinephrine potent vasoconstrictor adrenaline=Increase BP Adrenal Medullas only disease:

PHEOCHROMOCYTOMA- presence of tumor at adrenal medulla


-increase nor/epinephrine. HPN with pounding headache. -with HPN and resistant to drugs -drug of choice: beta blockers -complication: HPN crisis = lead to stroke -no valsalva maneuver. Sont smoke. No caffeine.

Adrenal Cortex

1. 2.

Zona fasiculata secrets glucocorticoids. Ex. Cortisol - Controls glucose metabolism (SUGAR) Zona reticularis secrets traces of glucocorticoids & androgenic hormones M testosterone F estrogen & progesterone Fx promotes development of secondary sexual characteristics

3. Zona glomerulosa - secretes mineralcortisone. Ex. Aldosterone Fx: promotes Na & H2O reabsorption & excretion of potassium (SALT)
ADDISONS DISEASE Steroids-lifetime
Decreased adrenocortical hormones leading to: a.) Metabolic disturbances (sugar) b.) F&E imbalances- Na, H2O, K c.) Deficiency of neuromuscular function (salt & sex) Predisposing Factors: 1. Atrophy of adrenal gland 2. Fungal infections 3. Tubercular infections S/Sx: 1. Decrease sugar Hypoglycemia Decreased glucocorticoids - cortisol

T tremors, tachycardia I - irritability R - restlessness E extreme fatigue D diaphoresis, depression 2. Decrease plasma cortisol Decrease tolerance to stress lead to Addisonians crisis

3. Decrease salt Hyponatermia Decreased mineralocorticoids - Aldosterone Hypovolemia a.) Hypotension

30

4.

5. 6.

b.) Signs of dehydration extreme thirst, agitation c.) Wt loss Hyperkalemia a.) Irritability b.) Diarrhea c.) Arrhythmia Decrease sexual urge or libido- Decreased Androgen Loss of pubic and axillary hair

To Prevent STD Local practice monogamous relationship CGFNS/NCLEX condom 7. Pathognomonic sign bronze like skin pigmentation due to decrease cortisol will stimulate pituitary gland to release melanocyte stimulating hormone. Dx Proc: 1. FBS decrease FBS (N 80 120 mg/dL) 2. Plasma cortisol decreased Serum Na decreased (N 135 145 meg/L) 3. Serum K increased (N 3.5 5.5 meg/L) Nsg Mgt:

1.

Monitor VS, I&O to determine presence of Addisonian crisis 15. Complication of Addisons dse : Addisonian crisis 16. Results the acute exacerbation of Addisons dse characterized by : Hypotension, hypovolemia, hyponatremia, wt loss, arrhythmia 17. Lead to progressive stupor & coma Nsg Mgt Addisonian Crisis (Coma) Assist in mechanical ventilation Adm steroids Force fluids

1. 2. 3.

2.

Administer meds a.) Corticosteroids - (Decadron) or Dexamethazone - Hydrocortisone (cortisone)- Prednisone Nsg Mgt with Steroids 1. Adm 2/3 dose in AM & 1/3 dose in PM in order to mimic the normal diurnal rhythm. 2. Taper the dose (w/draw, gradually from drug) sudden withdrawal can lead to addisonian crisis 3. Monitor S/E (Cushings syndrome S/Sx) a.) HPN b.) Hirsutism c.) Edema d.) Moon face & buffalo hump e.) Increase susceptibility to infection sue to steroids- reverse isolation b.) Mineralocorticoids ex. Flourocortisone

3. 4. 5. 6. 7.

Diet increase calorie or CHO Increase Na, Increase CHON, Decrease K Force fluid Administer isotonic fluid as ordered Meticulous skin care due to bronze like

HT & discharge planning a) Avoid precipitating factors leading to Addisonian crisis 1. Sudden withdrawal crisis 2. Stress 3. Infection

31

b) Prevent complications Addisonian crisis & Hypovolemic shock

8. 9.

Hormonal replacement therapy lifetime Important: follow up care

CUSHINGS SYNDROME increase secretion of adrenocortical hormone


Predisposing Factors: 1. Hyperplasia of adrenal gland 2. Tubercular infection milliary TB S/Sx 1. Increase sugar Hyperglycemia 3 Ps 1. Polyuria 2. Polydipsia increase thirst 3. Polyphagia increase appetite Classic Sx of DM 3 Ps & glycosuria + wt loss 2. Increase susceptibility to infection due to increased corticosteroid 3. Hypernatrermia a. HPN b. Edema c. Wt gain d. Moon face Buffalo hump Obese trunk classic signs Pendulous abdomen Thin extremities 4. Hypokalemia a. Weakness & fatigue b. Constipation c. ECG (+) U wave 5. Hirsutism increase sex 6. Acne & striae 7. Increase muscularity of female Dx: 1. FBS increase (N: 80-120mg/dL) 2. Plasma cortisol increase 3. Na increase (135-145 meq/L) 4. K- decrease (3.5-5.5 meq/L) Nsg Mgt: 1. Monitor VS, I&O 2. Administer meds a. K- sparing diuretics (Aldactone) Spironolactone - promotes excretion of NA while conserving potassium Not lasix due to S/E hypoK & Hyperglycemia! 3. 4. Restrict Na Provide Dietary intake low in CHO, low in Na & fats High in CHON & K Weigh pt daily & assess presence of edema- measure abdominal girth- notify doc. Reverse isolation Skin care due acne & striae Prevent complication - Most feared arrhythmia & DM (Endocrine disorder lead to MI Hypothyroidism & DM) Surgical bilateral Adrenolectomy Hormonal replacement therapy lifetime due to adrenal gland removal- no more corticosteroid!

5.

6.
7.

8. 9.

32

PANCREAS behind the stomach, mixed gland both endocrine and exocrine gland
Acinar cells (exocrine gland) Secrete pancreatic juices at pancreatic ducts. Aids in digestion (in stomach) Islets of Langerhans (endocrine gland ductless) cells secrets glucagon Fxn: hyperglycemia (high glucose) Cells Secrets insulin

Fxn: hypoglycemia Delta Cells Secrets somatostatin Fxn: antagonizes growth hormone

3 disorders of the Pancreas 1. DM 2. Pancreatic Cancer 3. Pancreatitis

Overview only:

PANCREATITIS (check page 72) acute inflammation of pancreas leading to pancreatic edema, hemorrhage & necrosis due to
Autodigestion self-digestion Cause: unknown/idiopathic 18. Or alcoholism Pathognomonic sign- (+) Cullens sign - Ecchymosis of umbilicus (bluish color)- pasa (+) Grey turners sign ecchymosis of flank area

Both sx means hemorrhage

CHRONIC HEMORRHAGIC PANCREATITIS- bangugot


Predisposing factors - unknown Risk factor: 1. History of hepatobiliary disorder 2. Alcohol 3. Drugs thiazide diuretics, oral contraceptives, aspirin, penthan 4. Obesity 5. Hyperlipidemia 6. Hyperthyroidism 7. High intake of fatty food saturated fats

33

DIABETES MELLITUS - metabolic disorder characterized by non utilization of CHO, CHON,& fat metabolism
Classification: I. Type I DM (IDDM) Juvenile onset, common in children, non-obese brittle dse -Insulin dependent diabetes mellitus Incidence rate 1.) 10% of population with DM have Type I Predisposing Factor: 1. 90% hereditary total destruction of pancreatic dells 2. Virus 3. Toxicity to carbon tetrachloride 4. Drugs Steroids both cause hyperglycemia Lasix - loop diuretics S/Sx: 3 PS + G 1.) Polyuria 2.) Poydipsia 3.) Polyphagia 4.) Glycosuria 5.) Weight loss 6.) Anorexia 7.) N/V 8.) Blurring of vision 9.) Increase susceptibility to infection 10.) Delayed/ poor wound healing Mgt: 1.

Insulin Therapy Diet Exercise Complications Diabetic Ketoacidosis (DKA) Diabetic Ketoacidosis (DKA) due to increase fat catabolism or breakdown of fats DKA (+) fruity or acetone breath odor Kassmauls respiration rapid, shallow breathing Diabetic coma (needs oxygen)

II. Type II DM (NIDDM)


Adult/ maturity onset type age 40 & above, obese Incidence Rate 1. 90% of pop with DM have Type II Mid 1980s marked increase in type II because of increase proliferation of fast food chains! Predisposing Factor: 1. Obesity obese people lack insulin receptors binding site 2. Hereditary S/Sx: 1. 2. Tx: 1. 2. 3.

Asymptomatic 3 Ps and 1G Oral Hypoglycemic Agents (OHA) Diet Exercise

Complication: HONKC

34

H hyper O osmolar N non K ketotic C coma III. GESTATIONAL DM occurs during pregnancy & terminates upon delivery of child Predisposing Factors: 1. Unknown/ idiopathic 2. Influence of maternal hormones S/Sx : Same as type II 1. Asymptomatic 2. 3 Ps & 1G Type of delivery CS due to large baby Sx of hypoglycemia on infant 1. High pitched shrill cry 2. Poor sucking reflex IV. DM ASSOCIATED WITH OTHER DISORDER a.) Pancreatic tumor b.) Cancer c.) Cushings syndrome

3 MAIN FOOD GROUPS Anabolism 1. CHON glucose 2. CHON amino acids 3. Fats fatty acids

Catabolism glycogen nitrogen free fatty acids (FFA) Cholesterol & Ketones

Pancreas glucose ATP (Main fuel/energy of cell ) Reserve glucose glycogen Liver will undergo glucogenesis synthesis of glucagons & Glycogenolysis breakdown of glucagons & Gluconeogenesis formation of glucose form CHO sources CHON & fats Hyperglycemia pancreas will not release insulin. Glucose cant go to cell, stays at circulation causing hyperglycemia. increase osmotic diuresis glycosuria Lead to cellular starvation

Lead to wt loss

stimulates the appetite/ satiety center (Hypothalamus) Polyphagia

polyuria Cellular dehydration Stimulates thirst center (hypothalamus) Polydipsia

Increased CHON catabolism Lead to (-) nitrogen balance Tissue wasting (cachexia)

35

Increase fat catabolism Free fatty acids Cholesterol Atherosclerosis HPN ketones DKA coma death

MI

stroke

DIABETIC KETOACIDOSIS (DKA)


Acute complication of Type I DM due to severe hyperglycemia leading to CNS depression & Coma. Ketones- a CNS depressant

Predisposing factor: 1. Stress between stress and infection, stress causes DKA more. 2. Hyperglycemia 3. Infection S/Sx: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 3 Ps & 1G Polyuria Polydipsia Polyphagia Glycosuria Wt loss Anorexia, N/V (+) Acetone breath odor- fruity odor Kussmaul's resp-rapid shallow respiration CNS depression Coma

pathognomonic DKA

Dx Proc: 1. FBS increase, Hct increase (compensate due to dehydration) N =BUN 10 -20 mg/100ml --increased due to severe dehydration Crea - .8 1 mg/100ml Hct 42% (should be 3x high)-nto hgb

Nsg Mgt: 1. Can lead to coma assist mechanical ventilation 2. Administer .9NaCl isotonic solution Followed by .45NaCl hypotonic solution To counteract dehydration. 3. Monitor VS, I&O, blood sugar levels 4. Administer meds as ordered: a.) Insulin therapy IV push Regular Acting Insulin clear (2-4hrs, peak action) b.) To counteract acidosis Na HCO3 c.) Antibiotic to prevent infection Insulin Therapy A. Sources: 1. Animal source beef/ pork-rarely used. Causes severe allergic reaction. 2. Human has less antigenecity property Cause less allergic reaction. Humulin If kid is allergic to chicken dont give measles vaccine due it comes from chicken embryo.

36

3.

Artificially compound

B. Types of Insulin 1. Rapid Acting Insulin - Ex. Regular acting I 2. Intermediate acting I - Ex. NPH (non-protamine Hagedorn I) 3. Long acting I - Ex. Ultra lente Types of Insulin 1. Rapid 2. Intermediate 3. Long acting color & consistency clear cloudy cloudy onset peak duration 2-4h 6-12h 12-24h -

Ex. 5am Hemoglucose test (HGT) 250 mg/dl Adm 5 units of RA I Peak 7-9am monitor hypoglycemic reaction at this time- TIRED Nsg Mgt: upon injection of insulin: 1.Administer insulin at room temp! To prevent lipodystrophy = atrophy/ hypertrophy of SQ tissues 2. Insulin is only refrigerated once opened! 3. Gently roll vial bet palms. Avoid shaking to prevent formation of bubbles. 4. Use gauge 25 26needle tuberculin syringe 5. Administer insulin at either 45(for skinny pt) or 90 (taba pt)depending on the client tissue deposit. 6. Dont aspirate after injection 7. Rotate injection site to prevent lipodystrophy 8. Most accessible site abdomen 9. When mixing 2 types of insulin, aspirate 1st regular/ clear before cloudy to prevent contaminating clear insulin & to promote accurate calibration. 10. Monitor signs of complications: a. Allergic reactions lipodystrophy b. Somogyis phenomenon hypoglycemia followed by periods of hyperglycemia or rebound effect of insulin. 11. 1ml or cc of tuberculin = 100 units of insulin

- - 1 cc = 100 units - - .5cc = 50 units - - .1 cc = 10 units

6 units RA

Most Feared Complication of Type II DM Hyper osmolarity = severe dehydration Osmolar Non - absence of lipolysis Ketotic - no ketone formation Coma S/Sx: headache, restlessness, seizure, decrease LOC = coma Nsg Mgt; - same as DKA except dont give NaHCO3! 1.Can lead to coma assist mechanical ventilation 2. Administer .9NaCl isotonic solution Followed by .45NaCl hypotonic solution

37

To counteract dehydration. 3.Monitor VS, I&O, blood sugar levels 4.Administer meds a.) Insulin therapy IV b.) Antibiotic to prevent infection Tx: O ral H ypoglycemic A gents 19. Stimulates pancreas to secrete insulin Classifications of OHA 1. First generation Sulfonylurear a. Chlorpropamide (diabenase) b. Tolbutamide (orinase) c. Tolazamide (tolinase) 2. 2nd generation sulfonylurear a. Diabeta (Micronase) b. Glipside (Glucotrol)

Nsg Mgt or OHA 1. Administer with meals to lessen GIT irritation & prevent hypoglycemia 2. Avoid alcohol (alcohol + OHA = severe hypoglycemic reaction=CNS depression=coma) Antabuse-Disufram Dx for DM 1. FBS N 80 120 mg/dl = Increased for 3 consecutive times + 3 Ps & 1G 2. Oral glucose tolerance (OGTT) - Most sensitive test 3. Random blood sugar increased 4. Alpha Glucosylated Hgb elevated Nsg Mgt; 1. Monitor for PEAK action of OHA & insulin Notify Doc 2. Monitor VS, I&O, neurocheck, blood sugar levels. 3. Administer insulin & OHA therapy as ordered. 4. Monitor signs of hyper & hypoglycemia. Pt DM hinimatay 20. You dont know if hypo or hyperglycemia. Give simple sugar (Brain can tolerate high sugar, but brain cant tolerate low sugar!) Cold, clammy skin hypo Orange Juice or simple sugar / warm to touch hyper adm insulin 5. Provide nutritional intake of diabetic diet: CHO 50% CHON 30% Fats 20% -Or offer alternative food products or beverage. -Glass of orange juice. 6. Exercise after meals when blood glucose is rising. 7. Monitor complications of DM a. Atherosclerosis HPN, MI, CVA b. Microangiopathy small blood vessels Eyes diabetic retinopathy , premature cataract & blindness Kidneys recurrent pyelonephritis & Renal Failure (2 common causes of Renal Failure : DM & HPN) c. Gangrene formation d. Peripheral neuropathy

=confirms DM!!

38

8.

1. Diarrhea/ constipation 2. Sexual impotence e. Shock due to cellular dehydration Foot care mgt a. Avoid waking barefooted b. Cut toe nails straight c. Apply lanolin lotion prevent skin breakdown d. Avoid wearing constrictive garments

9. Annual eye & kidney exam 10. Monitor urinalysis for presence of ketones Blood or serum more accurate 11. Assist in surgical wound debridement 12. Monitor signs or DKA & HONKC 13. Assist surgical procedure BKA or above knee amputation

Overview: HEMATOLOGICAL SYSTEMS


I Blood 55% Plasma, 45% cellular/ formed elements II Blood vessels III Blood forming organs 1. Thymus removed myasthenia gravis 2. Liver largest gland 3. Lymph nodes 4. Lymphoid organs payers patch 5. Bone marrow 6. Spleen destroys RBC Blood vessels 1. Veins SVC, IVC, Jugular vein blood towards the heart 2. Artery carries blood away from the 21. Aorta, carotid 3. Capillaries Blood 45% formed elements 55% plasma fluid portion of vlood. Yellow color. Serum Plasma CHONs (Produced in Liver) 1. Albumin- largest, most abundant plasma Maintains osmotic pressure preventing edema FXN: promotes skin integrity 2. Globulins alpha transports steroids Hormones & bilirubin - Transports iron & copper Gamma transport immunoglobulins or antibodies (Acute or Chronic) 3. Prothrombin and Fibrinogen clotting factor to prevent bleeding Cellular Elements: 1. RBC (erythrocytes) Spleen life span = 120 days (N) 3 6 M/mm3 - Anucleated - Biconcave discs - Has molecules of Hgb (red cell pigment) Transports & carries O2

39

SICKLE CELL ANEMIA sickle shaped RBC. Should be round. Impaired circulation of RBC. -immature cells=hemolysis of RBC=decreased hgb
3 Nsg priority 1. AIRWAY (priority) avoid deoxygenating activities - High altitude is bad 2. Fluid deficit promote hydration 3. Pain & comfort Hgb ( hemoglobin)- red cell pigment which transport O2 F= 12 14 gms % M = 14-16 gms % Hct 3x hgb 12 x 3 = 36 (hamatocrit) F 36 42% 14 x 3 = 42 *Hematocrit is the red cell pigment in whole blood M 42 48% *Erythropoietin- stimulate bone marrow to produce RBC Average 42% - Red cell percentage in whole red

Substances needed for maturation of RBC a.) Folic acid b.) Iron c.) Vit C d.) Vit B12 (cyanocobalamin) e.) Vit B6 (Pyridoxine) f.) Intrinsic factor Pregnant: 1st trimester- Folic acid prevent neural tube deficit 3rd tri iron Life span of rbc 80 120 days. Destroyed at spleen.

WBC leukocytes 5,000 10,000/mm3 GRANULOCYTES 1. Polymorphonuclearneutrophils Most abundant 60-70% WBC - fx short term phagocytosis For acute inflammation 2. PM Basophils -Involved in Parasitic infection - Release of chemical mediators for inflammation -Serotonin, histamine, prostaglandin, bradykinins 3. PM Eosinophils - Allergic reactions NON-GRANULOCYTES 1. Monocytes (macrophage) - largest WBC - involved in long term phagocytes - For chronic inflammation - Other name macrophage Macrophage in CNS- microglia Macrophage in skin Histiocytes Macrophage in lungs alveolar macrophage Macrophage in Kidneys Kupffer cells 2. Lymphocytes B Cell L bone marrow or bursa dependent T cell devt of immunity- target site for HIV NK cell natural killer cell Have both antiviral & anti-tumor properties

immunity

3.Platelets (thrombocytes) N- 150,000 450, 000/ mm3 it promotes hemostasis prevention of blood loss by activating clotting - Consists of immature or baby platelets known as megakaryocytes target of virus dengue - Normal lifespan 9 12 days

40

Drug of choice for HIV Zidovudine (AZT) or Ritonavir or Retrovir Standard precaution for HIV gloves, gown, goggles & mask Malaria night biting mosquito Dengue day biting mosquito Signs of platelet dys function: a.) Petechiae Hemophilia b.) Ecchymoses/ bruises DIC c.) Oozing or blood ON venipuncture site

ANEMIA
Iron deficiency Anemia chronic normocytic, hypochromic (pale), microcytic anemia due to inadequate absorption of iron leading to hypoxemic tissue injury. Incidence rate: 1. Common developed country due to high cereal intake Third leading cause of death in the US due to accidents 2. Common tropical countries blood sucking parasites 3. Women 15 35yo reproductive yrs 4. Common among the poor poor nutritional intake

THINGS TO REMEMBER: Suicide - common in teenagers Poisoning common in children (aspirin) Aspiration common in infant Accidents common in adults Choking common in toddler SIDS common in infant in US 22. Common in tropical zone Phil due blood sucks

Predisposing factors: 1. Chronic blood loss a. Trauma b. Mens c. GIT bleeding: i. Hematemesisii. Melena upper GIT duodenal cancer iii. Hematochezia lower GIT large intestine fresh blood from rectum 2. Inadequate intake of food rich in iron A. Eggs B. Organ meats, eggs, oatmeals, dried fruits, legumes, raisins 3. Inadequate absorption of iron due to : a. Chronic diarrhea b. Malabsorption syndrome celiac disease-gluten free diet. Food for celiac pts- sardines c. High cereal intake with low animal CHON ingestion d. Subtotal gastrectomy- partial removal of the stomach 4. Improper cooking of food

S/Sx: 1. 2. 3. 4. 5. 6.

Usually asymptomatic Weakness and Fatigue Headache, dizziness, dyspnea, palpitations, cold sensitivity, gen body malaise, pallor Brittle hair, spoon shaped nails (KOILONYCHIA)=Dec O2=hypoxia=atrophy of epidermal cells Atropic glossitis, dysphagia, stomatitis Pica abnormal craving for non edible food (caused by hypoxia=dec tissue perfusion=psychotic behavior)

41

Brittle hair, spoon shaped nail atrophy of epidermal cells N = capillary refill time < 2 secs N = shape nails biconcave shape, 180 Atrophy of cells Plummer Vinsons Syndrome due to cerebral hypoxia 1. Atropic glossiti s inflammation of tongue due to atrophy of pharyngeal and tongue cells 2. Stomatitis mouth sores 3. Dysphagia

Dx Proc: 1. RBC 2. Hgb 3. Reticulocyte 4. Hct 5. Iron 6. Ferritin Nsg Mgt 1. Monitor signs of bleeding of all hema test including urine & stool, GIT 2. Complete bed rest dont overtire pt =weakness and fatigue=activity intolerance 3. Encourage iron rich food 23. Raisins, legumes, egg yolk 4. Instruct the pt to avoid taking tea - impairs iron absorption 5. Administer meds a.) Oral iron preparation Ferrous SO4 Fe gluconate Fe Fumarate Nsg Mgt oral iron meds: 1. Administer with meals to lessen GIT irritation 2. If diluting in iron liquid prep adm with straw Straw 1. 2. 3. 4. Lugols Tetracycline Oral iron Macrodantine 3. 4. a. b. c. d. e. Give Orange juice for iron absorption Monitor & inform pts S/E Anorexia n/v Abdominal pain Diarrhea or constipation Melena

If pt cant tolerate oral iron prep administer parenteral iron prep example: 1. Iron dextran (IV, IM) 2. Sorbitex (IM) Nsg Mgt parenteral iron prep 1. Administer of use Z tract method to prevent discomfort, discoloration leakage to tissues. 2. Dont massage injection site. Ambulate to facilitate absorption. 3. Monitor S/E: a.) Pain at injury site b.) Localized abscess (nana/ pus formation) c.) Lymphadenopathy d.) Fever/ chills e.) Urticaria itchiness f.) Hypotension anaphylactic shock

42

Anaphylactic shock give epinephrine

PERNICIOUS ANEMIA - megaloblastic, chronic anemia due to deficiency of intrinsic factor leading to
Hypochlorhydria decrease Hcl acid secretion. Lifetime B12 injections. With CNS involvement. Predisposing factor 1. Subtotal gastrectomy partial removal stomach 2. Hereditary 3. Inflammatory dse of ileum 4. Autoimmune 5. Strict vegetable diet STOMACH Parietal or argentaffin Oxyntic cells Fxn produce intrinsic factor For reabsorption of B12 For maturation of RBC Fxn secrets Hcl acid Fx aids in digestion

6. Diet high caloric or CHO to correct wt loss S/Sx: 1. 2.

Headache dizziness, dyspnea, palpitations, cold sensitivity, gen body malaise, pallor GIT changes a. Red beefy tongue PATHOGNOMONIC mouth sores b. Dyspepsia indigestion c. Wt loss d. Jaundice 3. CNS Most dangerous anemia: pernicious due to neuroglogic involvement. a. Tingling sensation b. Paresthesia c. (+) Rombergs test (Ataxia) d. Psychosis Dx: Schillings testmeasures reabsorption of Vit B12 Confirmatory: absence of intrinsic factor Nsg Mgt Pernicious anemia 1. Enforce CBR 2. Administer B12 injections at monthly intervals for lifetime as ordered. IM- dorsogluteal or ventrogluteal. Not given oral due pt might develop resistance to drug Does not develop toxicity because of it is water soluble therefore it is easily excreted 3. Diet high calorie or CHO. Increase CHON, iron & Vit C 4. Avoid irritating mouthwashes. Use of soft bristled toothbrush is encouraged. Provide oral care 5. Avoid applying electric heating pads or any heat application can lead to burns

APLASTIC ANEMIA stem cell disorder due to bone marrow depression leading to pancytopenia all RBC are decreased
Decrease RBC Anemia Increase WBC leukocytocystosis Increase RBC polycythemia vera complication stroke, CVA, thrombosis decrease WBC leukopenia decrease platelets thrombocytopenia

43

Predisposing factors leading to Aplastic Anemia 1. Chemicals Banzene & its derivatives 2. radiation 3. Immunologic injury 4. Drugs cause bone marrow depression a. Broad spectrum antibiotic - Chloramphenicol - Sulfonamides bactrim b. Chemo therapeutic agents Methotrexate alkylating agents Nitrogen mustard anti metabolic Vincristine plant alkaloid S/Sx: 1. Anemia: a. Weakness & fatigue b. Headache, dizziness, dyspnea c. cold sensitivity, pallor d. palpitations 2. Leukopenia increase susceptibility to infection 3. Thrombocytopenia a. Petecchiae b. Oozing of blood from venipuncture site c. ecchymoses Dx: 1. CBC pancytopenia 2. Bone marrow biopsy/ aspiration at post iliac crest reveals fatty streaks in bone marrow Nsg Mgt: 1. Removal of underlying cause 2. Blood transfusion as ordered 3. Complete bed rest 4. O2 inhalation 5. Reverse isolation due leukopenia 6. Monitor signs of infection 7. Avoid SQ, IM or any venipuncture site = HEPLOCK 8. Use electric razor when shaving to prevent bleeding 9. Administer meds Immunological injury: give steroids Immunosuppresants: Anti lymphocyte globulin (Alg) given via central venous catheter, 6 days 3 weeks to achieve max therapeutic effect of drug. BLOOD TRANSFUSION: Objectives: 1. To replace circulating blood volume 2. To increase O2 carrying capacity of blood 3. To combat infection if theres decrease WBC 4. To prevent bleeding if theres platelet deficiency Nsg Mgt & principles in Blood Transfusion 1. Proper refrigeration 2. Proper typing & crossmatching Type O universal donor AB universal recipient 85% of people are RH (+) 3. Asceptically assemble all materials needed: a.) Filter set b.) Isotonic or PNSS or .9NaCl to prevent Hemolysis Hypotonic sol swell or burst Hypertonic sol will shrink or crenate c.) Needle gauge 18 - 19 or large bore needle to prevent hemolysis.

44

d.) Instruct another RN to recheck the following . Pts name, blood typing & cross typing, expiration date, serial number. e.) Check blood unit for presence of bubbles, cloudiness, dark in color & sediments indicates bacterial contamination. Dont dispose. Return to blood bank. f.) Never warm blood products may destroy vital factors in blood. - Warming is done if with warming device only in EMERGENCY! For multiple BT. - Within 30 mins room temp only! g.) Blood transfusion should be completed < 4hrs because blood that is exposed at room temp for > 2h causes blood deterioration may cause bacterial contamination. h.) Avoid mixing or administering drug at BT line leads to hemolysis i.) Regulate BT 15-20 gtts/min KVO or 100cc/hr to prevent circulatory overload j.) Monitor VS before, during & after BT especially q15 mins(local board) for 1st hour. NCLEX-q5min for 1st 15min. - Majority of BT reaction occurs within 1h.

BT reactions S/Sx Hemolytic reaction: H hemolytic Reaction 1. Headache, dizziness, dyspnea, palpitation, lumbar/ sterna/ flank pain, A allergic Reaction hypotension, flushed skin , (red) port wine urine. P pyrogenic Reaction C circulatory overload A air embolism T - thrombocytopenia C citrate intoxication expired blood =hyperkalemia H hyperkalemia Nsg Mgt: Hemolytic Reaction: 1. Stop BT 2. Notify Doc 3. Flush with plain NSS 4. Administer isotonic fluid sol to prevent acute tubular necrosis & conteract shock 5. Send blood unit to blood bank for reexamination 6. Obtain urine & blood samples of pt & send to lab for reexamination 7. Monitor VS & Allergic Rxn

Allergic Reaction:
S/Sx 1. 2. 3. 4. 5. Fever/ chills Urticaria/ pruritus Dyspnea Laryngospasm/ bronchospasm Bronchial wheezing

Nsg Mgt: 1. Stop BT 2. Notify Doc 3. Flush with PNSS 4. Administer antihistamine diphenhydramine Hcl (Benadryl). Give bedtime.SE-Adult-drowsiness. Child-hyperactive If (+) Hypotension anaphylactic shock administer epinephrine 5. Send blood unit to blood bank 6. Obtain urine & blood samples send to lab 7. Monitor VS & IO 8. Adm antipyretic & antibiotic for pyrogenic Rxn & TSB

Pyrogenic Reaction:
S/Sx a.) Fever/ chills b.) Headache c.) Dyspnea d. tachycardia e. palpitations f. diaphoresis

45

Nsg Mgt: 1. 2. 3. 4. 5. 6. 7. 8. Stop BT Notify Doc Flush with PNSS Administer antipyretics, antibiotics Send blood unit to blood bank Obtain urine & blood samples send to lab Monitor VS & IO Tepid sponge bath offer hypothermic blanket

Circulatory Overload:
Sx a. b. c. d. Dyspnea Orthopnea Rales or crackles Exertional discomfort

Nsg Mgt: 1. Stop BT 2. Notify Doc. Dont flush due pt has circulatory overload. 3. Administer diuretics Loop (Furosemide) Priority cases: Hemolytic Rxn 1st due to hypotension 1st priority attend to destruction of Hgb O2 brain damage Allergic 3rd Pyrogenic 4th Circulatory 2nd Hemolytic Anaphylitic 2nd 1st priority

PLATELET DISORDERS DIC DISSEMINATED INTRAVASCULAR COAGULATION


24. Acute hemorrhagic syndrome char by wide spread bleeding & thrombosis due to a defiency of clotting factors (Prothrombin & Fibrinogen). Predisposing factor: 1. Rapid BT 2. Massive trauma 3. Massive burns 4. Septicemia 5. Hemolytic reaction 6. Anaphylaxis 7. Neoplasia growth of new tissue 8. Pregnancy S/Sx

46

1. 2. 3.

Petechiae widespread & systemic (lungs, lower & upper trunk) Ecchymoses widespread Oozing of blood from venipunctured site

4. 5. 6.

Hemoptysis cough blood Hemorrhage Oliguria late sx

Dx Proc 1. CBC reveals decrease platelets 2. Stool for occult blood (+) Specimen stool 3. Opthalmoscopic exam sub retinal hemorrhage 4. ABG analysis metabolic acidosis

R O M E

pH pH ph ph ph

HCO3 PCO2 PCO2 HCO3 HCO3

respiratory alkalosis respiratory acidosis metabolic alkalosis metabolic acidosis

Diarrhea met acidosis Vomitting met alk Pyloric stenosis met alkalosis vomiting Ileostomy or intestinal tubing met acidosis Cushings met alk DM met acid Chronic bronchitis resp acid with hypoxemia, cyanosis Nsg Mgt DIC 1. 2. 3. 4. a. b. 5. Monitor signs of bleeding hema test + urine, stool, GIT Administer isotonic fluid solution to prevent shock. Administer O2 inhalation Administer meds Vit K aquamephyton Pitressin or vasopressin to conserve water NGT lavage - Use iced saline lavage- for decompensation, iced saline is used 6. Monitor NGT output 7. Provide heplock 8. Prevent complication: hypovolemic shock Late signs of hypovolemic shock: anuria Oncologic Nsg: Oncology study of neoplasia new growth

Benign (tumor) Diff - well differentiated Encapulation (+) Metastasis (-) Prognosis good Therapeutic modality surgery

Malignancy (cancer) poorly or undifferentiated (-) (+) poor 1. Chemotherapy plenty S/E 2. Radiation 3. Surgery most preferred treatment 4. Bone marrow transplant - Leukemia only

Predisposing factors: (carcinogenesis) G genetic factors I immunologic factors V viral factors a. Human papiloma virus causing warts b. Epstein barr virus E environmental Factors 90% a. Physical irradiation, UV rays, nuclear explosion, chronic irritation, direct trauma b. Chemical factors - Food additives (nitrates - Hydrocarbon vesicants, alkalies - Drugs (stillbestrol) - Uraehane - Hormones - Smoking Male 3.) Prostate cancer - common 40 & above (middle age & above) BPH 50 & above 1.) Lung cancer 2.) Liver cancer Female

47

1. Breast cancer 40 yrs old & up mammography 15 20 mins (SBE 7 days after mens) 2. Cervical cancer 90% multi sexual partners 5% early pregnancy 3. Ovarian cancer Classes of cancer Tissue typing 1. Carcinoma arises from surface epithelium & glandular tissues 2. Sarcoma- from connective tissue or bones 3. Multiple myeloma from bone marrow Pathological fracture of ribs & back pain 4. Lymphoma from lymph glands 5. Leukemia from blood Warning / Danger Sx of CA C change in bowel /bladder habits A a sore that doesnt heal U unusual bleeding/ Discharge T thickening of lump breast or elsewhere I indigestion? Dysphagia O obvious change in wart/ mole N nagging cough/ hoarseness U unexplained anemia A - anemia S sudden wt loss L loss of wt Therapeutic Modality: 1. Chemotherapy use various chemotherapeutic agents that kills cancer cells & kills normal rapidly producing cells GIT, bone marrow, and hair follicle. Classification: a.) Alkylating agents b.) Plant alkaloids vincristine c.) Anti metabolites nitrogen mustard d.) Hormones DES Steroids e.) Antineoplastic antibiotics S/E & mgt GIT - -Nausea & vomiting Nsg Mgt: 1. Administer anti emetic 4 6h before start of chemo Plasil 2. Withhold food/ fluid before start of chemo 3. Provide bland diet post chemo 25. Non irritating / non spicy - Diarrhea 1. Administer anti diarrheal 4 6h before start of chemo 2. Monitor urine, I&O qh - Stomatitis/ mouth sores 1. Oral care offer ice chips/ popsickles 2. Inform pt hair loss temporary alopecia Hair will grow back after 4 6 months post chemo. -Bone marrow depression anemia 1. Enforce CBR 2. O2 inhalation 3. Reverse isolation 4. Monitor signs of bleeding Repro organ sterility 1. Do sperm banking before start of chemo Renal system increase uric acid 1. Administer allopurinol/ xyloprin (gout) 26. Inhibits uric acid 27. Acute gout colchicines 28. Increase secretion of uric acid Neurological changes peristalsis paralytic ileus Most feared complication ff any abdominal surgery Vincristine plant alkaloid causes peripheral neuropathy

2. Radiation therapy involves use of ionizing radiation that kills cancer cells & inhibit their growth & kill N rapidly producing
cells.

Types of energy emitted 1. Alpha rays rarely used doesnt penetrate skin tissues 2. Beta rays internal radiation more penetration 3. Gamma ray external radiation penetrates deeper underlying tissues Methods of delivery

48

1. External radiation- involves electro magnetic waves Ex. cobalt therapy 2. Internal radiation injection/ implantation of radioisotopes proximal to CA site for a specific period of time. 2 types: a.) Sealed implant radioisotope with a container & doesnt contaminate body fluid. b.) Unsealed implant radioisotope without a container & contaminates body fluid. Ex. Phosphorus 32 3 Factors affecting exposure: A.) Half life time period required for half of radioisotopes to decay. - At end of half life less exposure B.) Distance the farther the distance lesser exposure C. ) Time the shorter the time, the lesser exposure D.) Shielding rays can be shielded or blocked by using rubber gloves & gamma use thick lead on concrete. S/E & Mgt: a.) Skin errythema, redness, sloughing 1. Assist in battling pt 2. Force fluid 2,000 3,000 ml/day 3. Avoid lotion or talcum powder skin irritation 4. Apply cornstarch or olive oil b.) GIT nausea / vomiting 1. Administer antiemetic 4 6h before start of chemo - Plasil 2 Withhold food/ fluid before start of chemo 3. Provide bland diet post chemo Non irritating / non spicy Dysglusia decrease taste sensitivity -When atrophy papilla (taste buds) 40 yo Stomatitis c.) Bone marrow depression 1. Enforce CBR 2. O2 inhalation 3. Reverse isolation 4. Monitor signs of bleeding

Overview of function & structure of the heart


HEART - Muscular, pumping organ of the body - Left mediastinum - Weigh 300 400 grams - Resembles a closed fist - Covered by serous membrane pericardium Pericardium

Parietal layer (outer)

Pericardial Fluid to prevent Friction rub (10-20 cc)

Visceral layer (inner)

Layer 1. 2. 3.

Epicardium outermost Myocardium inner responsible for pumping action/ most dangerous layer - cardiogenic shock - may lead to myocarditis, which may lead to RHD Endocardium innermost layer

Chambers 1. Upper collecting/ receiving chamber - Atria 2. Lower pumping/ contracting chamber - Ventricles Valves 1. Atrioventricular valves - Tricuspid & mitral valve Closure of AV valves gives rise to 1st heart sound or S1 or lub 2. Semi lunar valve a.) Pulmonic b.) Aortic Closure of semilunar valve gives rise to 2nd heart sound or S2 or dub Extra heart Sound S3 ventricular Gallop CHF S4 atrial gallop MI, HPN Coronary Arteries- arise from base of the aorta Right main coronary artery Supply the Left main coronary artery myocardium

Heart conduction system 1. Sino atrial node (SA node) (or Keith-Flock node) Loc junction of SVC & Rt atrium Fx- primary pace maker of heart

49

2.

3.

4.

-Initiates electric impulse of 60 100 bpm Atrioventicular node (AV node or Tawara node) Loc inter atrial septum Delay of electric impulse to allow ventricular filling (for about ,08millisecond) Bundle of His location interventricular septum Rt main Bundle Branch Lt main Bundle Branch Purkinje Fibers Loc- walls of ventricles leading to Ventricular contractions

SA node

AV

Purkenjie Fibers Bundle of His Complete heart block or the bundle block insertion of pacemaker at Bundle Branch is needed Metal Pace Maker change q3 5 yo Prolonged PR atrial fib ST segment depression angina ST elev MI T wave inversion MI widening QRS arrhythmia

CAD coronary artery dse or Ischemic Heart Dse (IHD) ==Nsg Mgt: decrease myocardial workload

Stages: 1. Atherosclerosis Myocrdial injury 2. Angina Pectoris Myocardial ischemia 3. MI- myocardial necrosis

ARTERIOSCLEROSIS
- Narrowing of artery due to fat - lipid deposits at tunica intima. Artery tunica adventitia outer - Tunica intima innermost - Tunica media middle ATHEROSCLEROSIS Predisposing Factor 1. Sex male 2. Black race 3. Hyperlipidemia, increase in saturated fats 4. Smoking 5. HPN 6. DM 7. Oral contraceptive- prolonged use 8. Sedentary lifestyle 9. Obesity 10. Hypothyroidism 11. Stress Signs & Symptoms 1. Chest pain 2. Dyspnea 3. Tachycardia 4. Palpitations 5. Diaphoresis Treatment P percutaneous T tansluminar C coronary A angioplasty

ATHEROSCLEROSIS
- Hardening or artery due to calcium & CHON deposits at tunica media.

For single occluded vessels

50

Obj: 1. 2. 3. To revascularize the myocardium To prevent angina Increase survival rate

PTCA done to pt with single occluded vessel . Multiple occluded vessels C coronary A arterial for 2 or more occluded vessels B bypass A and G graft surgery Nsg Mgt Before CABAG 1. Deep breathing cough exercises 2. Use of incentive spirometer 3. Leg exercises

ANGINA PECTORIS- A clinical syndrome characterized by paroxysmal chest pain usually relieved by REST or NGT
nitroglycerin, resulting fr temp myocardial ischemia. Predisposing Factor: (same with CAD) 1. sex male 2. black race 3. hyperlipidemia 4. smoking 5. HPN 6. DM 7. oral contraceptive prolonged 8. sedentary lifestyle 9. obesity 10. hypothyroidism Precipitating factors 4 Es 1. Excessive physical exertion 2. Exposure to cold environment - Vasoconstriction 3. Extreme emotional response 4. Excessive intake of food saturated fats Signs & Symptoms 1. Initial symptoms Levines sign hand clutching of chest 2. Chest pain sharp, stabbing excruciating pain. Location substernal -radiates back, shoulders, axilla, arms & jaw muscles -relieve by rest or NGT 3. Dyspnea 4. Tachycardia 5. Palpitation 6. diaphoresis Diagnosis 1. History taking & PE 2. ECG ST segment depression 3. Stress test treadmill = abnormal ECG 4. Serum cholesterol & uric acid - increase Nursing Management 1.) Enforce CBR 2.) Administer meds as ordered NTG small doses venodilator Large dose vasodilator 1st dose NTG give 3 5 min 2nd dose NTG 3 5 min 3rd & last dose 3 5 min Still painful after 3rd dose notify doc. MI! 55 yrs old with chest pain: 1st question to ask pt: what did you do before you had chest pain. 2nd question: does pain radiate? If chest pain radiates heart in nature. If not radiate pulmonary origin (PTB, Pneumonia, Emphysema) Nitroglycerin- act as Venodilator (if given in small doses) dilate veins of lower ext increase venous pooling lead to decrease venous return. Large doses- vasodilators

Meds: A. NTG- Nsg Mgt: 1. Keep in a dry place. 2. Avoid moisture & heat, sunlight may inactivate the drug.

51

3.

4. 5. 6.

Monitor S/E: orthostatic hypotension dec bp transient headache dizziness Rise slowly from sitting position Assist in ambulation. If giving NTG via patch: i. avoid placing it near hairy areas-will dec drug absorption (SHAVE AREA) ii. avoid rotating transdermal patches- will dec drug absorption iii. avoid placing near microwave oven or during defibrillation-will burn pt due aluminum foil in patch

3.) 4.) 5.) 6.) 7.)

B. Beta blockers PROPANOLOL (inderal) C. ACE inhibitors CAPTOPRIL D. Ca antagonist - NIFEDIPINE Administer O2 inhalation Semi-fowler Diet- Decrease Na and saturated fats, caffeine Monitor VS, I&O, ECG HT: Discharge planning: a. Avoid precipitating factors 4 Es b. Prevent complications MI c. Take meds before physical exertion-to achieve maximum therapeutic effect of drug d. Importance of follow-up care.

MI MYOCARDIAL INFARCTION heart attack terminal stage of CVD characterized by malocclusion leading to
necrosis and scarring Types: A. According to Location 1. 2. Trasmural MI most dangerous MI Mal-occlusion of both R&L coronary artery Sub-endocardial MI mal-occlusion of either R & L coronary artery

Most critical period upon dx of MI 48 to 72hmost dangerous hours: first 6-8 hours (majority of arrythmias occur, PVCs) - Majority of pt suffers from PVC premature ventricular contraction. B. According to mortality Killip I 15-20% chance of mortality (75-80% survival) Killip II 30-35% mortality Killip III- 45-50% mortality Killip IV- 65-70% mortalityspiritual support is needed, pt chronically ill characterized by cardiogenic shock

Predisposing factors 1. sex male 2. black raise 3. hyperlipidemia 4. smoking 5. HPN 6. DM 7. oral contraceptive prolonged 8. sedentary lifestyle 9. obesity 10. hypothyroidism

Signs & symptoms 1. chest pain excruciating, visceral pain located substernal or precodial area (rare) - radiates back, arm, shoulders, axilla, jaw & abd muscles (abdominal ischemia). - not usually relived by rest or NTG 2. dyspnea 3. Hyperthermia 4. initial increase in BP 5. mild restlessness & apprehensions 6. cool, moist ashen skin 7. occasional findings a.) split S1 & S2 b.) pericordial friction rub c.) rales /crackles d.) S4 (atrial gallop) (MI and Hypertension)

Diagnostic Exam 1. cardiac enzymes a.) CPK MB Creatinine Phosphokinase (12-24H)--increased b.) LDH lactic acid dehydrogenase--increased c.) SGPT (ALT) Serum Glutanic Pyruvate Transaminase- increased d.) SGOT (AST) Serum Glutamic Oxaloacetic - increased 2. Troponin test increase 3. ECG tracing ST segment increase/elevation, T wave inversion, widening or QRS complexes means arrhythmia in MI indicating PVC 4. serum cholesterol & uric acid - increase 5. CBC increase WBC

Nursing Management 1. Narcotic analgesics Morphine SO4 to induce vasodilation & decrease levels of anxiety. 2. Administer O2 inhalation low inflow (CHF-increase inflow)2-3L/min (high inflow may lead to respiratory arrest) 3. Enforce CBR without BRP a.) use Bedside commode 4. Avoid Valsalva maneuver (give laxatives) 5. Semi fowler 6. Provide a general liquid to soft diet that is low in saturated fats, Na, caffeine 7. Monitor VS, I&O & ECG tracings 8. Take 20 30 ml/week wine, brandy, or whisky to induce vasodilation. 9. Assist in surgical; CABAG Complications: 1. Pneumonia 2. Thrombophlebitis 3. Infarction 10. Provide pt HT a.) Avoid modifiable risk factors (diet, lifestyle)

52

b.) Prevent complications: 1. Arrhythmias PVC 2. Shock cardiogenic shock. Late signs of cardiogenic shock in MI oliguria 3. Thrombophlebitis - deep vein thrombosis 4. CHF left sided 5. Dresslers syndrome post MI syndrome -Resistant to medications -Administer 150,000 450,000 units of streptokinase c.) Strict compliance to meds - Vasodilators 1. NTG 2. ISOSURBIDE DINITRATE (Isordil) - Antiarrythmic 1. Lydocaine blocks release of norepinephrine 2. Bretylium - Beta-blockers lol 1. PROPANOLOL (Inderal) - ACE inhibitors - pril 1. CAPTOPRIL (Enalapril) - Ca antagonist 1. NIFEDIPINE - Thrombolytics or fibrinolytics to dissolve clots/ thrombus

S/E allergic reactions/ uticaria 1. StreptokinaseS/E: allergic reaction (urticaria or pruritus) bec Streptokinase is a foreign protein substance 2. Urokinase 3. Tissue plasminogen activating factorS/E: chest pain Monitor for bleeding: - Anticoagulants 1. Heparin (short acting) PTT If prolonged bleeding Antidote Protamine sulfate - Anti platelet PASA (aspirin)anti-thrombotic properties C/I: Dengue, vasoconstrictors, unknown cause of headache

2. Coumadin (Warfarin) delayed reaction takes 2 3 days to take effect PT prolonged bleeding antidote Vit K

d.) Resume ADL sex/ activity 4 to 6 weeks Post-cardiac rehab 1.)Sex as an appetizer rather then dessert Before meals not after, due after meals increase metabolism heart is pumping hard after meals. 2.) Position non-weight bearing position. When to resume sex/ act: When pt can already use staircase, then he can resume sex. e.) Diet decrease Na, Saturated fats, and caffeine f.) Teach importance of follow up care.

CHF CONGESTIVE HEART FAILURE - Inability of heart to pump blood towards systemic circulation.
- Backflow 1.) Left sided heart failure: Predisposing factors: 1.) 90% mitral valve stenosis due RHD, aging RHD affects mitral valve streptococcal infection Dx: - Aso titer anti streptolysine O > 300 total units Drugs given - Steroids - Penicillin - Aspirin Complication: RS-CHF Aging degeneration / calcification of mitral valve Ischemic heart disease HPN, MI, Aortic stenosis S/Sx Pulmonary congestion/ Edema 1. Dyspnea 2. Orthopnea (Diff of breathing- put patient on sitting pos platypnea)2-3 pillows or high fowlers 3. Paroxysmal nocturnal dysnea PNO- nalulunod (DOB at night) 4. Productive cough with blood tinged sputum 5. Frothy saliva (from lungs) 6. Cyanosis 7. Rales/ crackles due to fluid

53

8. 9. 10. 11. 12.

Bronchial wheezing PMI displaced lateral due cardiomegaly Pulsus alternons weak- pulse followed by alternating strong bounding pulse Anorexia & general body malaise S3 ventricular gallop

Dx 1. 2. CXR cardiomegaly PAP Pulmonary Arterial Pressure PCWP Pulmonary CapillaryWedge Pressure PAP measures pressure of R ventricle. Indicates cardiac status. PCWP measures end systolic/ diastolic pressure PAP & PCWP: Swan Ganz catheterization cardiac catheterization is done at bedside at ICU Operating room: laryngeal/throat cancer- tracheostomy set (Trachesostomy bedside) - Done 5 20 mins scalpel & trachesostomy set CVP indicates fluid or hydration status (N: 4-10cm of H2O) Increase CVP decrease flow rate of IV Decrease CVP increase flow rate of IV Echocardiography reveals enlarged heart chamber or cardiomyopathy ABG PCO2 increase, PO2 decrease = = hypoxemia = resp acidosis

3. 4.

2.) Right sided HF Predisposing factor 1. 90% - tricuspid stenosis 2. COPD 3. Pulmonary embolism 4. Pulmonic stenosis 5. Left sided heart failure S/Sx Venous congestion - Neck or jugular vein distension - Pitting edema - Ascites - Wt gain - Hepatomegalo/ splenomegaly - Jaundice - Pruritus - Esophageal varies - Anorexia, gen body malaise Diagnosis: 1. 2. CXR cardiomegaly CVP measures the pressure at R atrium Normal: 4 to 10 cm of water Increase CVP > 10 hypervolemia give loop diuretics Decrease CVP < 4 hypovolemia (fluid challenge by inc IVF rate) Flat on bed post of pt when giving CVP Position during CVP insertion Trendelenburg to prevent pulmonary embolism & promote ventricular filling.

3. Echocardiography enlarged heart chamber / cardiomyopathy 4.Liver enzyme elevation SGPT ( ALT) SGOT AST Nsg mgt: Increase force of myocardial contraction = increase cardiac output 3 6L of CO enforce CBR 1. Administer meds: Tx for LSHF: M morphine SO4 to induce vasodilatation A aminophylline & decrease anxiety D digitalis (digoxin) D - diuretics O - oxygen G - gases a.) Cardiac glycosides Increase myocardial = increase CO Digoxin (Lanoxin). Antidote: digivine Digitoxin: metabolizes in liver not in kidneys not given if with kidney failure. b.) Loop diuretics: Lasix effect with in 10-15 min. Max = 6 hrs c.) Bronchodilators: Aminophyline (Theophyline). Avoid giving caffeine d.) Narcotic analgesic: Morphine SO4 - induces vasodilaton & decrease anxiety

54

e.) Vasodilators NTG f.) Anti-arrythmics Lidocaine Ethacrynic acid- Thiazide diuretics 2. Administer O2 inhalation high! @ 3 -4L/min via nasal cannula 3. High fowlers 4. Restrict Na! 5. Provide meticulous skin care 6. Weigh pt daily. Assess for pitting edema. Measure abdominal girth daily & notify MD 7. Monitor V/S, I&O, breath sounds, EKG tracings 8. Institute bloodless phlebotomy. Rotating tourniquet or BP cuff rotated clockwise q 15 mins = to promote decrease venous return 9. Diet decrease salt, fats & caffeine 10. HT: a) Complications :shock Arrhythmia Thrombophlebitis MI Cor Pulmonale RT ventricular hypertrophy b.) Dietary modifications c.) Adherence to meds

PERIPHERAL MUSCULAR DISEASE Arterial ulcers 1. Thromboangitis Obliterans (Buergers) male/ feet 2. Reynauds female/ hands venous ulcer 1. Varicose veins 2. Thrombophlebitis

1.) Thromboangitis obliterates/ BUERGERS arteries & veins of lower extremities. Male/ feet Predisposing factors: - Males greater than 30yo (high risk group) - Smokers

DISEASE- Acute inflammatory disorder affecting small to medium sized

S/Sx 1. Intermittent claudication leg pain upon walking - Relieved by rest 2. Cold sensitivity & skin color changes White Pallor bluish cyanosis red rubor

3. Decrease or diminished peripheral pulses - Post tibial, Dorsalis pedis 4. Trophic changes 5. Ulcerations 6. Gangrene formation

Dx: 1. 2. 3. Oscillometry decrease peripheral pulse volume. Doppler UTZ decrease blood flow to affected extremities. Angiography reveals site & extent of malocculsion.

Nsg Mgt: 1. Encourage a slow progression of physical activity a.) Walk 3 -4 x / day b.) Out of bed 2 3 x a / day 2. Meds a.) Analgesic b.) Vasodilator c.) Anticoagulant 3. Foot care mgt like DM a.) Avoid walking barefoot b.) Cut toe nails straight c.) Apply lanolin lotion prevent skin breakdown d.) Avoid wearing constrictive garments 4. Avoid smoking & exposure to cold environment 5. Assist patient in surgery: BKA (Below the knee amputation) 2.)REYNAUDS

PHENOMENON acute episodes of arterial spasm affecting digits of hands & fingers 55

Predisposing factors: 1. 2. 3. Female, 40 yrs Smoking Collagen dse a.) SLE pathognomonic sign butterfly rash on face Chipmunk face bulimia nervosa Cherry red skin carbon monoxide poisoning Spider angioma liver cirrhosis Caput medusae leg & trunk umbilicus- Liver cirrhosis Lion face leprosy b.) Rheumatoid arthritis Direct hand trauma piano playing, excessive typing, operating chainsaw 1. 2. Intermittent claudication - leg pain upon walking - Relieved by rest Cold sensitivity

4. S/Sx:

Nsg Mgt: a. Analgesics b. Vasodilators c. Encourage to wear gloves especially when opening a refrigerator. d. Avoid smoking & exposure to cold environment VENOUS ULCERS 1. VARICOSITIES / Varicose veins - Abnormal dilation of veins lower ext & trunk - Due to: a.) Incompetent valves leading to b.) Increase venous pooling & stasis leading to c.) Decrease venous return Predisposing factors: a. Hereditary b. Congenital weakness of veins c. Thrombophlebitis d. Heart dse e. Pregnancy f. Obesity g. Prolonged immobility - Prolonged standing S/Sx: 1. Pain especially after prolonged standing 2. Dilated tortuous skin veins 3. Warm to touch 4. Heaviness in legs Dx: 1. 2. Venography Trendelenbergs test vein distend quickly < 35 secs

Nsg Mgt: 1. Elevate legs above heart level to promote venous return 1 to 2 pillows 2. Measure circumference of leg muscles to determine if swollen. 3. Wear anti embolic or knee high stockings. Women panty hose 4. Meds: Analgesics 5. Surgery: vein sweeping & ligation Sclerotherapy spider web varicosities S/E thrombosis

THROMBOPHLEBITIS (deep vein thrombosis) - Inflammation of veins with thrombus formation


Predisposing factors: 1. Smoking 2. Obesity 3. Hyperlipedemia 4. Prolonged use of oral contraceptives 5. Chronic anemia 6. DM 7. MI 8. CHF 9. Postop complications 10. Post cannulation insertion of various cardiac catheters S/Sx: 1. 2. 3. Dx:

Pain at affected extremities Cyanosis (+) Homans sign - Pain at leg muscles upon dorsiflexion of foot. 1. Angiography

56

2. Doppler UTZ Nsg Mgt: 1. Elevate legs above heart level. 2. Apply warm, moist packs to decrease lymphatic congestion. 3. Measure circumference of leg muscles to detect if swollen. 4. Use anti embolic stockings. 5. Meds: Analgesics. Anticoagulant: Heparin 6. Complication:

Pulmonary Embolism:
- Sudden sharp chest pain - Dyspnea - Tachycardia - Palpitation - Diaphoresis - Mild restlessness OVERVIEW OF RESPIRATORY SYSTEM: I. Upper respiratory tract: Fx: 1. Filtering of air 2. Warming & moistening 3. Humidification a. Nose cartilage - Parts: Rt nostril separated by septum Lt nostril Consists of anastomosis of capillaries Liessel Bach Plexus site of epistaxis Pharynx (throat) muscular passageway for air& food Branches: 1. Oropharynx 2. Nasopharynx 3. Layngopharynx -

b.

c. Larynx voice box Fx: 1. For phonation- voice or speech production 2. Cough reflex Made up of framework: a. epiglottis b. hyoid bone c. thyroid & crichoid cartilage Glottis opening of larynx Opens to allow passage of air Closes to allow passage of food -Inability to cough, complete obstruction of airway II. Lower Respiratory tract Fx for gas exchange d. Trachea windpipe - has cartillagenous rings - site for permanent/ artificial a/w tracheostomy b. Bronchus R & L main bronchus c. Lungs R 3 lobes = 10 segments L 2 lobes 8 segments Post pneumonectomy - position affected side to promote expansion of lungs==Semi Fowlers Post segmental lobectomy position unaffected side to promote drainage Serous membrane Pleura Parietal Pleural Fluid Pleural Friction Rub ches pain- pain upon inspiration Pneumonia Pleurisy Pleural Effusion Lungs covered by pleural cavity, parietal lobe & visceral lobe Alveoli acinar cells - site of gas exchange (O2 & CO2)-diffusion - diffusion: Daltons law of partial pressure of gases - basic living units Powerful stimulating stimulantincrease CO2 COPD decrease O2 stimulant Visceral

57

Ventilation movement of air in & out of lungs Respiration movement of air into cells Type II cells of alveoli secretes surfactant, lipoprotein in nature Surfactant - decrease surface tension of alveoliprevents collapse of lungs also known as atelectasis Lecithin & spinogomyelin L/S ratio 2:1 indicator of lung maturity If 1:2 adm O2 - < 40% Concentration to prevent atelectasis & retinopathy or blindness. Retrolental Fibroplasia-retinopathy/blindness in prematurity

I. PNEUMONIA inflammation of lung parenchyma leading to pulmonary consolidation as alveoli is filled with exudates. Etiologic agents: 1. Streptococcus pneumoniae (pnemococcal pneumonia) 2. Haemophilus pneumoniae(Bronchopneumonia) in children 3. Escherichia coli 4. Klebsiella P. 5. Diplococcus P. High risk: elderly & children below 5 yo bec of low resistance

Predisposing factors: 1. Smoking 2. Air pollution 3. Immuno-compromised patients a. AIDS PLP b. Bronchogenic CA - Non-productive to productive cough-- CXR 4. Prolonged immobility CVA- hypostatic pneumonia 5. Aspiration of food 6. Over fatigue S/Sx: 1. 2. 3. 4. 5. 6. 7. 8. Productive cough pathognomonic: greenish to rusty sputum Dyspnea with prolonged respiratory grunt Fever, chills, anorexia, gen body malaise Wt loss Pleuritic friction rub Rales/ crackles Cyanosis Abdominal distension leading to paralytic ileus (absence of peristalsis)

Sputum exam could confirm presence of TB & pneumonia Dx: 1. 2. 3. 4. Sputum GSCS- gram staining & culture sensitivity - Reveals (+) culture microorganism. CXR pulmonary consolidation CBC increase WBC and inc Erythrocyte sedimentation rate ABG PO2 decrease, hypoxemia

Nsg Mgt: Enforce CBR Strict respiratory isolation Meds: a.) Broad spectrum antibiotics Penicillin or tetracycline Macrolides ex azythromycin (zythromax) b.) Anti pyretics c.) Mucolytics or expectorants 4. Force fluids 2 to 3 L/day 5. Institute pulmonary toileta.) Deep breathing exercise b.) Coughing exercise c.) Chest physiotherapy cupping d.) Turning & reposition - Promote expectoration of secretions 6. Semi-fowler 7. Nebulize & suction as necessary, O2 inhalation 8. Comfy & humid environment 9. Diet: increase CHO or calories, CHON & Vit C 10. Postural drainage - To drain secretions using gravity Mgt for postural drainage: a.) Best done before meals (breakfast) or 2 4 hrs after meals to prevent Gastroesophageal Reflux 1. 2. 3.

58

b.) Monitor VS & breath sounds Normal breath sound bronchovesicular c.) Deep breathing exercises d.) Adm bronchodilators 15 30 min before procedure e.) Stop if pt cant tolerate procedure f.) Provide oral care it may alter taste sensation g.) C/I pt with unstable VS & hemoptysis, increase ICP, increase IOP (glaucoma) Normal IOP 12 21 mmHg 11. HT: a.) Avoidance of precipitating factors (smoking) b.) Complication: Atelectacies & meningitis c.) Compliance to meds

PULMONARY TUBERCULOSIS (KOCHS DSE) - Inflammation of lung tissue caused by invasion of mycobacterium TB
or tubercle bacilli or acid fast bacilli gram (+) aerobic, motile & easily destroyed by heat or sunlight. Predisposing factors: 1. Malnutrition 2. Overcrowding 3. Alcoholism 4. Ingestion of infected cattle (mycobacterium BOVIS) 5. Virulence 6. Over fatigue or stress S/Sx: 1. 2. 3. 4. 5. 6. 7. Productive cough yellowish Low grade afternoon fever Night sweats Dyspnea Anorexia, generalized body malaise, wt loss Chest/ back pain Hempotysis ==Airborne transmission, droplet nuclei infection

Diagnosis: 1. Skin test Mantoux test infection of Purified Protein Derivative PPD DOH 8-10 mm induration WHO 10-14 mm induration Result within 48 72h (+) Mantoux test previous exposure to tubercle bacilli Mode of transmission droplet infection 2. Sputum AFB (+) to cultured microorganism 3. CXR pulmonary infiltrate caseous necrosis 4. CBC increase WBC Nursing Mgt: 1. CBR 2. Strict resp isolation 3. O2 inhalation 4. Semi fowler 5. Force fluid to liquefy secretions 6. Deep breathing and cough exercises 7. Nebulize & suction if necessary 8. Provide comfortable & humid environment 9. Diet increase CHO & calories, CHON, Vit, minerals 10. Short course chemotherapy:

Intensive phase 1. INH isoniazid 2. Rifampicin - both given before meals for absorption - both given within 4 months, given simultaneously to prevent resistance -S/E: peripheral neutitis vit B6 (cereals, green leafy vegetables, organ meat) Rifampicin -All body secretions turn to red orange color urine, stool, saliva, sweat & tears.

3. PZA Pyrazinamide given 2 mos/ after meals. S/E: allergic rxn, nephrotoxicity & hepatoxicity PZA may be replaced by ETHAMBUTOL (S/E: optic neuritis) Standard regimen 1. Injection of streptomycin Aminoglycosides Ex. Kanamycin, gentamycin, neomycin S/E: a.) Ototoxicity damage CN # 8 tinnitus (ringing in the ears), dizziness, vertigo b.) Nephrotoxicicity monitor BUN (10-20) & Creatinine (.8-1) HT: a.) Avoid predisposing factors like alcoholism, crowded places b.) Provide the dietary intake of increased CHO,calories, CHONm and Vitamin C c.) Avoid complications: 1.) Atelectasis

59

2.) Miliary TB spread of Tb to other system d.) Strict compliance to meds (if one misses a dose, continue taking the meds) - Religiously take meds e) Know the importance of follow up care

HISTOPLASMOSIS- acute fungal infection caused by inhalation of contaminated dust with Histoplasma Capsulatum
transmitted from birds manure. S/Sx: Same as pneumonia & PTB like 1. Productive cough 2. Dyspnea 3. Chest & joint pains 4. Cyanosis 5. Anorexia, gen body malaise, wt loss 6. Hemoptysis 7. Fever and chills Dx: 1. 2. Histoplasmin skin test = (+) Histoplasma Capsulatum ABG pO2 decrease

Nsg Mgt: 1. CBR 2. Meds: a.) Antifungal agents Amphotericin B (Fungizone) S/E: a.) Nephrotoxcicity check BUN and Creatinine b.) Hypokalemia b.)Corticosteroids c.) Mucolytic/ or Expectorants 3. Administer O2, force fluids 4. Encourage deep breathing and coughing exercises 5. Nebulize, suction 6. Complications: a.) Atelectasis b.) Bronchiectasis COPD 7. Prevent spread of histoplasmosis: a.) Spray breading places or kill the bird.

COPD Chronic Obstructive Pulmonary Disease


1. 2. 3. 4. Chronic bronchitis Bronchial asthma Bronchiectasis Pulmonary emphysema terminal stage

CHRONIC BRONCHITIS - called BLUE BLOATERS inflammation of bronchus due to hypertrophy or hyperplasia of goblet
mucus producing cells leading to narrowing of smaller airways. Predisposing factors: 1. Smoking all COPD types 2. Air pollution S/Sx: 1. Productive cough 2. Dyspnea on exertion 3. Prolonged expiratory grunt 4. Scattered rales/ rhonchi 5. Cyanosis 6. Pulmonary HPN a.) Leading to peripheral edema b.) Cor pulmonale right ventricular hypertrophy --respiratory in origin 7. Anorexia, gen body malaise Dx: 1. ABG PO2 PCO2 Resp acidosis

Hypoxemia causing cyanosis - Complications: Emphysema and Pleurisy Nsg Mgt: (Same as emphysema) 2.) BRONCHIAL ASTHMA- reversible inflammation lung condition due to hyerpsensitivity to allergens leading to narrowing of smaller airways. Predisposing factor: 1. Extrinsic Asthma called Atopic/ allergic asthma a.) Pollen b.) Dust c.) Gases d.) Smoke/fumes

60

e.) Dander f.) Lints g.) Viral infection 2. Intrinsic Asthma- called Non-Atopic, non-allergic asthma Cause: Hereditary Drugs aspirin, penicillin, blockers (beta blockers are bronchoconstrictors) Food additives nitrites Foods seafood, chicken, eggs, chocolates, milk Physical/ emotional stress Sudden change of temp, humidity &air pressure 3. mixed type: combination of both extrinsic & intrinsic Asthma 90% cause of asthma S/Sx: 1. C cough non productive to productive 2. D dyspnea 3. W wheezing on expiration 4. Cyanosis 5. Mild apprehension & restlessness 6. Tachycardia & palpitation 7. Diaphoresis Dx: 1. Pulmo function test decrease vital lung capacity 2. ABG PO2 decrease, PCO2 increase- hypoxemia, Ph decreased Respiratory Acidosis Nsg Mgt: 1. CBR all COPD 2. Medsa.) Bronchodilator through inhalation or metered dose inhaled / pump. Given 1st before corticosteroids to facilitate absorption b.) Corticosteroids due inflammatory. Given 10 min after adm bronchodilator c.) Mucolytic/ expectorant d.) Mucomist (Acetylcysteine) at bedside put suction machine. e.) Antihistamine 3. Force fluids 4. Institute pulmonary toilet 5. O2 all COPD low inflow to prevent resp distress 6. Nebulize & suction client PRN 7. Diet: increase CHO, CHON 8. Semifowler all COPD except emphysema due late stage 9. HT a.) Avoid predisposing factors (dust, pollen, etc), provide a comfortable environment b.) Complications: Status astmaticus- give epinephrine & bronchodilators - Emphysema c.) Adherence to meds to prevent status asmaticus d.) Teach the importance of follow up care

BRONCHIECTASIS abnormal permanent dilation of bronchus resulting to destruction of muscular & elastic tissues of alveoli.
Predisposing factors: 1. Recurrent upper & lower respiratory tract infections 2. Congenital anomalies 3. Lung Tumors 4. Chest Trauma S/Sx: 1. Productive cough 2. Dyspnea 3. Anorexia, generalized body malaise- all energy are used to increase respiration. 4. Cyanosis 5. Hemoptisis

Dx: 1. 2. 3. ABG PO2 decrease Bronchoscopy direct visualization of bronchus using fiberscope. Chest xray Nsg Mgt: before bronchoscopy 1. Consent, explain procedure MD/ lab explain RN 2. NPO 3. Monitor VS 1. 2. 3. 4. Feeding after return of gag reflex Instruct client to avoid talking, smoking or coughing Monitor signs of frank or gross bleeding Monitor of laryngeal spasm DOB

Nsg Mgt after bronchoscopy

61

Prepare at bedside tracheostomy set

Mgt: same as emphysema except Surgery Pneumonectomy removal of affected lung lie on affected side Segmental lobectomy position of pt unaffected side to promote drainage

PULMONARY EMPHYSEMA irreversible terminal stage of COPD


- Characterized by inelasticity of alveolar walls leading to air trapping, leading to maldistribution of gases. - Body will compensate over distension of thoracic cavity - Barrel chest Predisposing factor: 1. Smoking 2. Allergy 3. Air pollution 4. High risk elderly (above 65yo) 5. Hereditary - 1 anti trypsin to release elastase for recoil of alveoli. S/Sx: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12.

Consistent productive cough Dyspnea at rest with prolonged expiratory grunt due terminal Anorexia & generalized body malaise Barrel chest Rales/ rhonchi Bronchial wheezing Decrease tactile fremitus (should have vibration) palpation 99. Decreased - with air or fluid Resonance to hyperresonance percussion Decreased or diminished breath sounds on affected lungs Pathognomonic: barrel chest increase post/ anterior diameter of chest Pursed lip breathing to eliminated CO2 Flaring of alai nares/ ala nasi 1. Pulmonary function test decrease vital lung capacity 2. ABG a.) Panlobular / centri lobular emphysema pCO2 increase pO2 decrease hypoxema resp acidosis Blue bloaters Chronic bronchitis b.) Panacinar/ Centriacinar pCO2 decrease pO2 increase hyperaxemia resp alkalosis Pink puffers

Diagnosis:

Nursing Mgt: 1. CBR 2. Meds a.) Bronchodilators b.) Corticosteroids- prone to infection c.) Antimicrobial agents d.) Mucolytics/ expectorants e.) Antipyretics PRN --Patient is prone to develop an infection O2 Low inflow to avoid rsp arrest Force fluids High fowlers Nebilize & suction Institute P posture E end E expiratory to prevent collapse of alveoli P pressure 8. HT a.) Avoid smoking b.) Prevent complications 1.) Cor pulmonale R ventricular hypertrophy 2.) CO2 narcosis lead to coma 3.) Atelectasis 4.) Pneumothorax air in pleural space 9. Adherence to meds 10. Encourage deep breathing and coughing exercises 11. Diet: increase CHO, DHON, vitamins and minerals 12. Importance of follow up care 3. 4. 5. 6. 7.

RESTRICTIVE LUNG DISORDER PNEUMOTHORAX partial / or complete collapse of lungs due to entry or air in pleural space. Types: 1. Spontaneous pneumothorax entry of air in pleural space without obvious cause. eg. Rupture of bleb (alveoli filled sacs) in pt with inflammed lung conditions 2. Open pneumothorax air enters pleural space through an opening in chest wall

62

-Stab/ gun shot wound 3. Tension Pneumothorax air enters plural space with @ inspiration & cant escape leading to over distension of thoracic cavity resulting to shifting of mediastinum content to unaffected side. Eg. Flail chest paradoxical breathing pattern Predisposing factors: 1. Chest trauma 2. Inflammatory lung conditions 3. Tumor S/Sx: 1. Sudden sharp chest pain 2. unexplained Dyspnea or SOB 3. Cyanosis 4. Diminished or decreased breath sound of affected lung 5. Cool moist skin- initial sign of shock 6. Mild restlessness/ apprehension, anxiety 7. Resonance to hyperresonance 8. decreased tactile fremitus Diagnosis: 1. ABG pO2 decrease 2. CXR confirms pneumothorax/ collapse of lung Nursing Mgt: 1. Assist in endotracheal intubation 2. Assist in thoracenthesis 3. Administer meds Morphine SO4 due to pain - Anti microbial agents- due to bacteria 4. Assist in test tube thoracotomy attached to H2O sealed drainage system Purpose of H2O sealed drainage 1. Restablish (-) pressure in the lungs- lung 6-12mm Hg 2. Promote reexpansion of the lungs 3. Drain fluid, blood and air 4. To prevent reflux of blood fluid and air

Nursing Mgt if pt is on CPT attached to H2O drainage 1. Maintain strict aseptic technique 2. DBE 3. At bedside a.) Petroleum gauze pad if dislodged Hemostat b.) If with air leakage clamp c.) Extra bottle 4. Meds Morphine SO4 Antimicrobial 5. Monitor & assess for oscillation fluctuations or bubbling a.) If (+) to intermittent bubbling means normal or intact - H2O rises upon inspiration - H2o goes down upon expiration b.) If (+) to continuous, remittent bubbling 1. Check for air leakage 2. Clamp towards chest tube 3. Notify MD c.) If (-) to bubbling 1. Check for loop, clots, and kink 2. Milk towards H2O seal 3. Indicates re-expansion of lungs 4. Auscultate for breath sounds, Xrays 5. Removal of CTT When will MD remove chest tube? 1. If (-) fluctuations 2. (+) Breath sounds 3. CXR full expansion of lungs Nursing Mgt of removal of chest tube 1. Encourage DBE 2. Instruct to perform Valsalva maneuver for easy removal, to prevent entry of air in pleural space. 3. Apply vaselinated air occlusive dressing - Maintain dressing dry & intact 4. Prepare: Extra bottle, excellent clamp, petroleum gauze GIT I. Upper alimentary canal - function for digestion a. Mouth b. Pharynx (throat) c. Esophagus d. Stomach- site of digestion e. 1st half of duodenum II. Middle Alimentary canal Function: for absorption - Complete absorption large intestine a. 2nd half of duodenum for absorption

63

b. Jejunum c. Ileum d. 1st half of ascending colon III. Lower Alimentary Canal Function: elimination a. 2nd half of ascending colon for elimination b. Transverse for complete absorption L I c. Descending colon d. Sigmoid e. Rectum IV. Accessory Organ a. Salivary gland b. Verniform appendix c. Liver d. Pancreas auto digestion e. Gallbladder storage of bile I. Salivary Glands 1. Parotid below & front of ear 2. Sublingual 3. Submaxillary Produces saliva for mechanical digestion 1,200 -1,500 ml/day - saliva produced Lacrimal gland- depression on the frontal bone Lacrimal duct- outer canthus

PAROTITIS mumps inflammation of parotid gland


-Paramyxovirus S/Sx: 1. 2. 3. 4. 5. Fever, chills anorexia, generalized body malaise enlarged parotid gland Swelling of parotid gland Dysphagia Earache otalgia

Mode of transmission: Direct transmission & droplet nuclei Incubation period: 14 21 days Period of communicability 1 week before swelling & immediately when swelling begins. Nursing Mgt: 1. CBR 2. Institute a strict respiratory isolation 3. Meds: analgesic Antipyretic Antibiotics to prevent 2 complications 4. Alternate warm & cold compress at affected part (vinegar promotes cooling) 5. General liquid to soft diet 6. Complications Women cervicitis, vaginitis, oophoritis Both sexes meningitis & encephalitis/ reason why antibiotics is needed Men orchitis might lead to sterility if it occurs during / after puberty. VERNIFORM APPENDIX Rt iliac or Rt inguinal area - Function lymphatic organ produces WBC during fetal life - ceases to function upon birth of baby

APENDICITIS inflamation of verniform appendix


Predisposing factor: 1. Microbial infection 2. Feacalith undigested food particles tomato seeds, guava seeds 3. Intestinal obstruction S/Sx: 1. 2. 3. 4. 5.

Pathognomonic sign: (+) rebound tenderness Low grade fever, anorexia, n/v Diarrhea &/ or constipation Pain at Rt iliac region-- MCBURNEYS point site of surgical incision Late sign due pain tachycardia

Diagnosis: 1. CBC mild leukocytosis increase WBC 2. PE (+) rebound tenderness (flex Rt leg, palpate Rt iliac area rebound) 3. Urinalysis(+) acetone in urine Treatment: - appendectomy 24 45 Nursing Mgt: 1. Secure consent 2. Routinary nursing measures: a.) Skin prep

64

b.) NPO c.) Avoid enema lead to rupture of appendix 3. Meds: Antipyretic Antibiotics *Dont give analgesic will mask pain - Presence of pain means appendix has not ruptured. 4. Avoid heat application will rupture appendix. 5. Monitor VS, I&O bowel sound 6. Maintain a patent IV line Complications: Peritonitis, Septicemia Nursing Mgt: post op 1. If (+) to Penrose drain indicates rupture of appendix Position- affected side to drain 2. Meds: analgesic due post op pain Antibiotics, Antipyretics PRN 3. Monitor VS, I&O, bowel sound- N- borborygmy sound 4. Maintain patent IV line 5. Complications- peritonitis, septicemia Liver largest gland - Occupies most of right hypochondriac region - Color: scarlet red, brown shiny and transparent - Covered by a fibrous capsule Glissons capsule - Functional unit liver lobules Function: 1. Produces bile Bile emulsifies fatsH2O and bile salts= cholesterol Right sided pain: Cholelithiasis- easy bruising Left sided pain: Pancreatitis - Composed of H2O & bile salts -Gives color to urine urobilin Stool color stechobilin Detoxifies drugs Promotes synthesis of vit A, D, E, K - fat soluble vitamins (needs fat for absorption)

2. 3.

Hypervitaminosis vit D & K Vit A retinol Def Vit A night blindness Vit D cholecalciferon - Helps calcium - Rickets, osteoarthritis 4. It destroys excess estrogen hormone 5. for metabolism A. CHO 1. Glycogenesis synthesis of glycogens 2. Glycogenolysis breakdown of glycogen 3. Gluconeogenesis formation of glucose from CHO sources B. CHON1. Promotes synthesis of albumin & globulin Liver Cirrhosis decrease albumin; ascites and edema Albumin maintains osmotic pressure, prevents edema 2. Promotes synthesis of prothrombin & fibrinogen 3. Promotes conversion of ammonia to urea. Ammonia like breath fetor hepaticus C. FATS promotes synthesis of cholesterol to neutral fats called triglycerides

LIVER CIRRHOSIS - lost of architectural design of liver leading to fat necrosis & scarring
Laennac Cirrhosis- loss of architectural design of the liver leading to fat necrosis and scarring Early sign hepatic encephalopathy 1. Asterixis flapping hand tremors Late signs headache, restlessness, disorientation, decrease LOC hepatic coma. Nursing priority assist in mechanical ventilation Predisposing factor: Decrease Laennacs cirrhosis caused by alcoholism 1. Chronic alcoholism- major cause 2. Malnutrition decreaseVit B, thiamin - primary cause 3. Virus 4. Toxicity- eg. Carbon tetrachloride (CCL4) 5. Use of hepatotoxic agents S/Sx: Early signs:

65

a.) b.) c.) d.) e.) f.) g.) h.) i.) j.) k.)

Weakness, fatigue Anorexia, n/v Stomatitis Urine tea color Stool clay color Amenorrhea Decrease sexual urge Loss of pubic, axilla hair Hepatomegaly Jaundice Pruritus or urticaria Decrease bowel sounds a.) Hematological changes all blood cells decrease Leukopenia- decrease Thrombocytopenia- bleeding tendencies Anemia- decrease b.) Endocrine changes Spider angiomas, Gynecomastia Caput medusae, Palmar errythema, loss of tortousity of the umbilicus c.) GIT changes Ascites, bleeding esophageal varices due to portal HPN d.) Neurological changes: hepatic encephalopathy

2. Late signs

Hepatic encephalopathy - ammonia (cerebral toxin) Late signs: Early signs: Headache and dizziness asterexis Fetor hepaticus (flapping hand tremors) Confusion Restlessness Decrease LOC Hepatic coma Diagnosis: 1. Liver enzymes- increase SGPT (ALT) SGOT (AST) Serum cholesterol & ammonia increase Indirect or conjugated bilirubin increase CBC - pancytopenia PTT prolonged bleeding Hepatic ultrasonogram fat necrosis of liver globules

2. 3. 4. 5. 6.

Nursing Mgt 1. CBR 2. Restrict Na! 3. Monitor VS, I&O 4. Weigh pt daily & assess pitting edema 5. Measure abdominal girth daily notify MD 6. Meticulous skin care 7. Diet increase CHO, vit & minerals. Moderate fats. Decrease CHON Well balanced diet 8. Complications of liver cirrhosis: a.) Ascites fluid in peritoneal cavity Nursing Mgt: 1. Meds: Loop diuretics 10 15 min effect 2. Assist in abdominal paracentesis - aspiration of fluid - Void before paracentesis to prevent accidental puncture of bladder as trochar is inserted b.) Bleeding esophageal varices - Dilation of esophageal veins 1. Meds: Vit K Pitressin or Vasopressin (IM) 2. NGT decompression- lavage - Give before lavage ice or cold saline solution - Monitor NGT output 3. Assist in mechanical decompression - Insertion of Sengstaken-Blackemore tube- to decompress veins of esophagus-to prevent esophageal varices - 3 lumen typed catheter - Scissors at bedside to deflate/decompress balloon. Prep scissors when pt complains of DOB c.) Hepatic encephalopathy 1. Assist in mechanical ventilation due coma 2. Monitor VS, neuro check 3. Siderails due restless

66

4.

Meds Laxatives to excrete ammonia (Lactulose)

HEPATITIS- jaundice (icteric sclera)


Bilirubin Kernicterus/ hyperbilirubinia Irreversible brain damage Pancreas mixed gland (exocrine & endocrine gland); found behind the stomach

PANCREATITIS acute or chronic inflammation of pancreas leading to pancreatic edema, hemorrhage & necrosis due to auto
digestion (self-digestion). Bleeding of pancreas - Cullens sign on umbilical area Predisposing factors: 1. Chronic alcoholism 2. Hepatobilary disease 3. Obesity 4. Hyperlipidemia 5. Hyperparathyroidism 6. Drugs Thiazide diuretics,aspirin, pills, Pentamidine HCL (Pentam) for clients with AIDS, 7. Diet increase saturated fats S/Sx: 1. Severe Lt epigastric pain radiates from back &flank area (left upper quadrant) - Aggravated by eating, accompanied by DOB 2. N/V 3. Tachycardia 4. Palpitation due to pain 5. Dyspepsia /indigestion 6. Decrease bowel sounds 7. (+) Cullens sign - ecchymosis of umbilicus hemorrhage 8. (+) Grey Turners spots ecchymosis of flank area 9. Hypocalcemia Diagnosis: 1. Serum amylase & lipase increase 2. Urine lipase increase 3. Serum Ca decrease Nursing Mgt: 1. Meds a.) Narcotic analgesic - Meperidine Hcl (Demerol) Dont give Morphine SO4 will cause spasm of sphincter. b.) Smooth muscle relaxant/ anti cholinergic - Ex. Papavarine Hcl Prophantheline Bromide (Profanthene) c.) Vasodilator NTG d.) Antacid Maalox e.) H2 receptor antagonist - Ranitidin (Zantac) to decrease pancreatic stimulation f.) Ca gluconate 2. Withold food & fluid aggravates pain 3. Assist in Total Parenteral Nutrition (TPN) or hyperalimentation Complications of TPN 1. Infectionmaintain a strict aseptic technique 2. Pulmonary Embolismcheck all connection to system 3. Hyperglycemia 4. Hyperkalemia 4. Institute stress mgt tech a.) DBE b.) Biofeedback 5. Comfy position - Knee chest or fetal lie position 6. If pt can tolerate food, give increase CHO, decrease fats, and moderate CHON 7. Complications: Chronic hemorrhagic pancreatitis, Peritonitis, Septicemia, Shock

GALLBLADDER storage of bile made up of cholesterol. CHOLECYSTITIS/ CHOLELITHIASIS inflammation of gallbladder with gallstone formation. Predisposing factor: 1. High risk women 40 years old 2. Post menopausal women undergoing estrogen therapy

67

3. 4. 5. 6. 7. S/Sx: 1. 2. 3. 4. 5. 6. 7. 8.

Obesity Sedentary lifestyle, prolonged immobility Hyperlipidemia Neoplasm Obstruction Severe Right abdominal pain (after eating fatty food). Occurring especially at night = epigastric or right abdominal quadrant after eating a heavy meal Fat intolerance Anorexia, n/v, feeling of fullness Jaundice Pruritus Easy bruising Tea colored urine Steatorrhea

Diagnosis: 1. Oral cholecystogram (or gallbladder series)- confirms presence of gall stones 2. Increased indirect bilirubin 3. Increased alkaline phosphatase 4. increased serum and amylase Nursing Mgt: 1. Meds a.) Narcotic analgesic - Meperdipine Hcl Demerol b.) Anti cholinergic/Anti-spasmodic - Atropine SO4 c.) Anti emetic Phenergan Phenothiazide with anti emetic properties d) Broad spectrum antibiotics 2. Diet increase CHO, moderate CHON, decrease fats 3. Meticulous skin care 4. Surgery: Cholecystectomy Nursing Mgt post cholecystectomy -Maintain patency of T-tube intact & prevent infection Stomach widest section of alimentary canal - J shaped structures 1. Anthrum 2. Pylorus 3. Fundus Valves prevent GERD 1. 1.cardiac sphincter valve 2. Pyloric sphincter valve- stomach and first half of duodenum Cells 1. Chief/ Zymogenic cells secrets a.) Gastric amylase - digest CHO/ sugars b.) Gastric lipase digest fats c.) Pepsin CHON d.) Rennin digests milk products Parietal / Argentaffin / oxyntic cells Function: a.) Produces intrinsic factor promotes reabsorption of vit B12 cyanocobalamin promotes maturation of RBC b.) Secrets Hcl acid aids in digestion Endocrine cells - Secretes gastrin increase Hcl acid secretion

2.

3.

Function of the stomach 1.Mechanical digestion 2.Chem. 3.Storage of food -CHO, CHON- stored 1 -2 hrs. Fats stored 2 3 hrs

PEPTIC ULCER DISEASE (PUD) excoriation / erosion of submucosa & mucosal lining due to:
a.) Hypercecretion of acid pepsin b.) Decrease resistance to mucosal barrier Incidence Rate: 1. Men 40 55 yrs old 2. Aggressive persons/ type A personality 3. Hereditary 4. Emotional Stress Predisposing factors: 1. Hereditary 2. Emotional 3. Smoking vasoconstriction GIT ischemia 4. Alcoholism stimulates release of histamine = Parietal cell release Hcl acid = ulceration 5. Caffeine tea, soda, chocolate 6. Irregular diet 7. Rapid eating 8. Ulcerogenic drugs NSAIDS, aspirin, steroids, indomethacin, ibuprofen

68

Indomethacin - S/E corneal cloudiness. Needs annual eye check up. NSAID and steroids= gastropathy 9. Gastrin producing tumor or gastrinoma Zollinger Ellisons syndrome 10. Microbial invasion helicobacter pylori. Metronidazole (Flagyl) Types of ulcers Ascending to severity 1. Acute affects submucosal lining 2. Chronic affects underlying tissues heals & forms a scar, deeper

According to location 1. Stress ulcer 2. Gastric ulcer 3. Duodenal ulcer most common Stress ulcers common among eritically ill clients 2 types 1. Curlings ulcer cause: trauma & Burns Hypovolemia GIT schemia Decrease resistance of mucosal barriers to Hcl acid Ulcerations 2. Cushings ulcer cause stroke/CVA/ head injury Increase vagal stimulation Hyperacidity Ulcerations Treatment: Vagotomy- done to prevent hemorrhage and shock prior to surgery on the stomach

SITE PAIN

GASTRIC ULCER Antrum or lesser curvature -30 min 1 hr after eating - epigastrium - gaseous & burning - not usually relieved by food & antacid

HYPERSECRETION VOMITING HEMORRHAGE WT COMPLICATIONS

Normal gastric acid secretion common hematemesis Wt loss a. stomach cancer b. hemorrhage HIGH RISK 60 years old and above 20 years old and above 90-95% are cases ofduodenal ulcers- less bicarbonate ions, decrease so increase incidence Diagnosis: 1. Endoscopic exam 2. Stool from occult blood (+) 3. Gastric analysis Gastric Ulcer: normal gastric acid secretion Duodenal: increased gastric acid secretion 4. GI series confirms presence of ulceration Nursing Mgt: 1. Diet bland, non irritating, non spicy 2. Avoid caffeine & milk/ milk products Increase gastric acid secretion 3. Administer meds a.) Antacids AAC Aluminum containing antacids Ex. aluminum hydroxide gel (Amphogel) S/E constipation

DUODENAL ULCER Duodenal bulb -2-3 hrs after eating - mid epigastrium - cramping & burning pain - usually relieved by food & antacid - 12 MN 3am pain Increased gastric acid secretion Not common Melena Wt gain a. perforation

Magnesium containing antacids ex. milk of magnesia S/E diarrhea

Maalox (fever S/E) b.) H2 receptor antagonist

69

1. 2. 3. Nursing Mgt:

Ex Ranitidine (Zantac) SE: fever Cimetidine (Tagamet)hastens the effect of oral anticoagulants Famotidine (Pepcid) SE: fever Avoid smoking decrease effectiveness of drug

Administer antacid & H2 receptor antagonist (Cimetidine) 1hr apart -Cemetidine decrease antacid absorption & vise versa c.) Cytoprotective agents Ex 1. Sucralfate (Carafate) - Provides a paste like subs that coats mucosal lining of stomach 2. Misoprostol (Cytotec) SE: menstrual spotting d.) Sedatives/ Tranquilizers - Valium, lithium e.)Anticholinergics / Antispasmodic 1. Atropine SO4 2. Prophantheline Bromide (Profanthene) 1. (Pt has history of hpn crisis with peptic ulcer disease. Rn should not administer alka seltzer- has large amount of Na. 3. Surgery: subtotal gastrectomy - Partial removal of stomach Billroth II (Gastrojejunostomy) - Removal of -3/4 of stomach & duodenal bulb & anastomostoses of gastric stump to jejunum.

Billroth I (Gastroduodenostomy) -Removal of of stomach & anastomoses of gastric stump to the duodenum.

Before surgery for BI or BII - Do vagotomy (severing of vagus nerve) & pyloroplasty (drainage) first. Nursing Mgt: 1. Monitor NGT output or drainage immediately post op- bright red a.) Immediately post op should be bright red b.) Within 36- 48h output is yellow green c.) After 48h output is dark red due to HCl acid 2. Administer meds: a.) Analgesic b.) Antibiotic c.) Antiemetics 3. Maintain patent IV line 4. VS, I&O & bowel sounds 5. Complications: a.) Hemorrhage hypovolemic shock Late signs anuria b.) Peritonitis c.) Paralytic ileus most feared d.) Hypokalemia e.) Thromobphlebitis f.) Pernicious anemia g.) Septicemia 7.)Dumping syndrome common complication rapid gastric emptying of hypertonic food solutions CHYME leading to hypovolemia. Sx of Dumping syndrome: 1. Dizziness 2. Diaphoresis 3. Diarrhea 4. Palpitations Nursing mgt: 1. Avoid fluids in chilled solutions, sweets (fluids must be taken after meals) 2. Small frequent feedings-6 equally divided feedings 3. Diet decrease CHO, moderate fats & CHON 4. Flat on bed 15 -30 minutes after q feeding

DIVERTICULITIS/DIVERTICULOSIS
1. 2. 3. A. Diverticulum- an outpouching of the intestinal mucosa particularly the sigmoid colon Diverticulosis- multiple diverticulum Diverticulitis- inflammation of diverticula Predisposing Factors 1. High Risk Groups- men (40-45yo) 2. Congenital weakness of muscle fibers of the intestine. 3. low roughage and fiber in the diet 1. 2. 3. Dx: 1. Barium enemareveals inflammatory process 2. CBC reveals: decreased hematocrit and hemoglobin Nsg Mgt: 1. Administer meds as ordered: Intermittent lower left abdominal quadrant pain, particularly in the rectosigmoid area tenderness alternating bouts of constipation or diarrhea with blood or mucous

S/S:

70

a. antibiotics b. bulk laxatives c. stool softeners d. anti spasmodic agents 2. Instruct clients to take foods high in fiber if there is diverticulosis 3. Monitor for signs of infection Feared complications: Peritonitis 4. Assists in surgical procedure Resection of the diseased bowel and creation of a colostomy

BURNS direct tissue injury caused by thermal, electric, chemical & smoke inhaled (TECS)
Nursing Priority infection (all kinds of burns) Head burn-priority- a/w 2nd priority for 1st & 2nd - pain 2nd priority for 3rd - F&E Thermal- direct contact flames, hot grease, sunburn. Electric, wires Chem. direct contact corrosive materials acids Smoke gas / fume inhalation Stages: 1. Emergent phase Removal of pt from cause of burn. Determine source or loc or burn 2. Shock phase 48 - 72. Characterized by shifting of fluids from intravascular to interstitial space =Hypovolemia S/Sx: -

BP decrease Urine output HR increase Hct increase Serum Na decrease Serum K increase Met acidosis

3. Diuretic/ Fluid remobilization phase - 3 to 5 days. Return of fluid from interstitial to intravascular space 4. Recovery/ convalescent phase complete diuresis. Wound healing starts immediately after tissue injury. Class: I. Partial Burn 1. 1st degree superficial burns - Affects epidermis - Cause: thermal burn - Painful - Redness (erythema) & blanching upon pressure with no fluid filled vesicles 2. 2nd degree deep burns - Affects epidermis & dermis - Cause chem. burns - very painful - Erythema & fluid filled vesicles (blisters) II Full thickness Burns 1. Third & 4th degrees burn - Affects all layers of skin, muscles, bones - Cause electrical - Less painful - Dry, thick, leathery wound surface known as ESCHAR devitalized or necrotic tissue. Assessment findings Rule of nines Head & neck = 9% Ant chest = 18% Post chest = 18% @ Arm 9+9 = 18% @ leg 18+18 = 18% Genitalia/ perineum= 1% Total 100% Nursing Mgt 1. Meds a.) Tetanus toxoid- burn surface area is source of anaerobic growth Claustridium tetany Tetany

Tetanolysin Hemolysis b.) Morphine SO4 c.) Systemic antibiotics

tetanospasmin muscle spasm

71

1. Ampicillin 2. Cephalosporin 3. Tetracyclin 4. Topical antibiotic : 1. Silver Sulfadiazene (silvadene) 2. Sulfamylon 3. Silver nitrate 4. Povidone iodine (betadine) 2. Administer isotonic fluid sol & CHON replacements 3. Strict aseptic technique 4. Diet increase CHO, increase CHON, increase Vit C, and increase K- orange 5. If (+) to burns on head, neck, face - Assist in intubation 6. Assist in hydrotherapy 7. Assist in surgical wound debridement. Administer analgesic 15 30 minutes before debridement 8. Complications: a.) Infection b.) Shock c.) Paralytic ileus - due to hypovolemia & hypokalemia d.) Curlings ulcer H2 receptor antagonist e.) Septicemia blood poisoning f.) Surgery: skin grafting GUT genito-urinary tract Function: 1. Promote excretion of nitrogenous waste products 2. Maintain F&E & acid base balance 1. Kidneys pair of bean shaped organ - Located retroperitonially (back of peritoneum) on either side of vertebral column. Encased in Bowmanss capsule. Parts: 1. 2. 3. Renal pelvis pyelonephritis inflammation of the renal pelvis Cortex Medulla

Nephrons basic living unit of the kidneys consisting of glomerulus Glomerulus filters blood going to kidneys Function of kidneys: 1. Urine formation 2. Regulation of BP Urine formation 25% of total CO (Cardiac Output) is received by kidneys (3,000-6,000 ml.) 125ml/ min filtered by the glomerulus > Glomerular filtration rate 1. Filtration 2. Tubular Reabsorption124ml of ultra filtered are reabsorbed in the blood 3. Tubular Secretion- 1 ml is excreted in the urine Filtration Normal GFR/ min is 125 ml of blood Tubular reabsorption 124ml of ultra infiltrates (H2O & electrolytes is for reabsorption) Tubular secretion 1 ml is excreted in urine Causes of CRF: 1. HPN 2. DM

Regulation of BP: Predisposing factor: Ex CS hypovolemia decrease BP going to kidneys Activation of RAAS Release of Renin (hydrolytic enzyme) at juxtaglomerular apparatus Angiotensin I mild vasoconstrictor Angiotensin II vasoconstrictor

Adrenal cortex Aldosterone

increase CO

increase PR

Increase BP Increase Na & H2O reabsorption Hypervolemia

72

Ureters 25 35 cm long, passageway of urine to bladder Bladder loc behind symphisis pubis. Muscular & elastic tissue that is distensible - Function reservoir of urine 1200 1800 ml Normal adult can hold 200 500 ml needed to initiate micturition reflex Color amber Odor aromatic Consistency clear or slightly turbid pH 4.5 8 Specific gravity 1.015 1.030 WBC/ RBC (-) Albumin (-) E coli (-) Mucus thread few Amorphous urate (-) Urethra extends to external surface of body. Passage of urine, seminal & vaginal fluids. - Women 3 5 cm or 1 to 1 - Male 20cm or 8

UTI CYSTITIS inflammation of bladder


Predisposing factors: 1. Microbial invasion E. coli 2. High risk women 3. Obstruction 4. Urinary retention 5. Increase estrogen levels 6. Sexual intercourse S/Sx: 1. Pain flank area 2. Urinary frequency & urgency 3. Burning upon urination 4. Dysuria & hematuria 5. Fever, chills, anorexia, gen body malaise 6. Nocturia Diagnosis: Urine culture & sensitivity - 80% of the cases are (+) to E. coli Nursing Mgt: 1. Force fluid 2000 ml= to prevent bacterial multiplication 2. Warm sitz bath to promote comfort 3. Monitor & assess for gross hematuria 4. Monitor and assess urine for color, odor, and bleeding N pH: 4.8 5. Acid ash diet cranberry, vit C -OJ to acidify urine & prevent bacterial multiplication 6. Meds: systemic antibiotics Ampicillin Cephalosporin Sulfonamides cotrimoxazole (Bactrim) - Gantrism (ganthanol) Aminoglycosides: Gentamycin Urinary antiseptics Nitrofurantoin (Macrodantin) Urinary analgesic- Pyridum 6. Ht a.) Importance of Hydration b.) Void after sex (male and female) c.) Female avoids cleaning back & front Bubble bath, Tissue paper, Powder, perfume d.) Complications: Pyelonephritis

PYELONEPHRITIS acute/ chronic infl of 1 or 2 renal pelvis of kidneys leading to tubular destruction, interstitial abscess
formation. - Lead to Renal Failure Predisposing factor: 1. Microbial invasion (Bacterial) a.) E. Coli b.) Streptococcus 2. Urinary retention /obstruction 3. Pregnancy 4. DM 5. Exposure to renal toxins or nephrotoxic agents

73

S/Sx: Acute pyelonephritis a.) Costovertibral angle pain, tenderness b.) Fever, anorexia, gen body malaise c.) Urinary frequency, urgency d.) Nocturia, dysuria, hematuria e.) Burning upon urination Chronic Pyelonephritis a.) Fatigue, wt loss, weakness b.) Polyuria, polydypsia c.) HPN Diagnosis: 1. Urine culture & sensitivity (+) E. coli & streptococcus 2. Urinalysis (+) WBC, (+)RBC, (+) Pus cells 3. Cystoscopic exam urinary obstruction Nursing Mgt: 1. Provide CBR especially during acute phase 2. Force fluid 3. Acid ash diet 4. Provide a warm sitz bath for comfort

5.

6.

Meds: a.) Urinary antiseptic nitrofurantoin (macrodantin) SE: peripheral neuropathy GI irritation Hemolytic anemia Staining of teeth b.) Urinary analgesic Pyridium Complication- Renal Failure

NEPHROLITHIASIS/ UROLITHIASIS- formation of stones at urinary tract


- calcium , milk oxalate, cabbage cranberries nuts tea chocolates uric acid anchovies organ meat nuts sardines

Predisposing factors: 1. Diet increase Ca & oxalate 2. Hereditary gout 3. Obesity 4. Sedentary lifestyle 5. Hyperparathyroidism S/Sx: 1. Renal colic 2. Cool moist skin (shock) 3. Burning upon urination 4. Hematuria 5. Anorexia, n/v Diagnosis: 1. IVP intravenous pyelography. Reveals location of stone 2. KUB reveals location of stone 3. Cytoscopic exam- urinary obstruction 4. Stone analysis composition & type of stone 5. Urinalysis increase EBC, increase CHON Nursing Mgt: 1.Force fluid 2.Strain urine using gauze pad 3.Warm sitz bath for comfort 4.Alternate warm compress at flank area 5. a.) Narcotic analgesic- Morphine SO4 b.) Allopurinol (Zyeoprim) c.) Patent IV line d.) Diet if + Ca stones acid ash diet If + oxalate stone alkaline ash diet - (Ex milk/ milk products) If + uric acid stones decrease organ meat / anchovies sardines 6. Surgery a.) Nephectomy removal of affected kidney Litholapoxy removal of 1/3 of stones- Stones will recur. Not advised for pt with big stones b.) Extracorporeal shock wave lithotripsy - Non - invasive - Dissolve stones by shock wave 7. Complications: Renal Failure

74

BENIGN PROSTATIC HYPERTROPHY - enlarged prostate gland leading to


a.) Hydro ureters dilation of ureters b.) Hydronephrosis dilation of renal pelvis c.) Kidney stones Stone formation-- Renal failure d.) Renal failure encircles the neck of the bladder decreased form of urinary stream Caurse is unknown

Predisposing factor: 1. High risk 50 years old & above 60 70 (3 to 4 x at risk) Prostate cancer: 40 years old & above 2. Influence of male hormone S/Sx: 1.Decrease force of and amount of urinary stream 2.Dysuria 3.Hematuria 4.Burning upon urination 5.Terminal dribblingearly sign of BPH 6.Backache 7.Sciatica 8. Hesitancy Diagnosis: 1. Digital rectal exam enlarged prostate gland 2. KUB urinary obstruction 3. Cystoscopic exam obstruction 4. Urinalysis increase WBC, CHON, RBC Nursing Mgt: 1. Prostatic message promotes evacuation of prostatic fluid 2. Limit fluid intake 3. Provide catheterization 4. Provide a warm sitz bath for comfort 5. Meds: a. Terazozine (hytrin) - Relaxes bladder sphincter, relaxes the smooth muscle of urinary sphincter S/E: HA, hypotension b. Fenasteride (Proscar) - Atrophy of Prostate Gland (given after meals) S/E: N&V, Anorexia 5. Surgery: Prostatectomy TURP- Transurethral resection of Prostate- No incision Without incision: for debilitated clients -Assist in cystoclysis or continuous bladder irrigation. Complication: 1. Hemorrhage 2. Urinary obstruction 3. Penile dysfunction Nursing mgt: c. d. 3. Monitor signs and symptoms of infection Monitor symptoms gross/ frank bleeding. Normal bleeding within 24h. Maintain irrigation or tube patent to flush out clots - to prevent bladder spasm & distention

ACUTE RENAL FAILURE sudden immobility of kidneys to excrete nitrogenous waste products & maintain F&E balance
due to a decrease in GFR. (N 125 ml/min) Predisposing factors: Pre renal cause- decrease blood flow Causes: 1. Septic shock 2. Hypovolemia 3. Hypotension 4. CHF 5. Hemorrhage 6. Dehydration (chronic diarrhea)

decrease flow to kidneys

Intra-renal cause involves renal pathology= kidney problem 1. Acute tubular necrosis 2. Pyelonephritis Post renal cause involves mechanical obstruction Causes: 1. Urinary strictures 2. Urolithiasis 3. BPH 4. Presence of tumors Stages: **I. OLIGURIC STAGE (1-2 weeks)

3. 4.

HPN Acute Glumerulonephritis

75

involves passage of urine < 400ml/day S/S: a. Hyperkalemia- arrhythmia b. Hypernatremia c. Hyperphosphatemia d. Hypocalcemia e. High BUN 10-20 and creatinine .8-1 f. Metabolic acidosis 1-2wks II. DIURETIC PHASE 2-3 weeks --increased amount of urine -S/S: a. Hypokalemia b. Hyponatremia c. Metabolic Acidosis d. Increased Creatinine and BUN III. CONVALESCENT/RECOVERY PHASE9-12 months

CHRONIC RF irreversible loss of kidney function


Predisposing factors: 1. DM 2. HPN 3. Recurrent UTI/ nephritis/ pyelonephritis 4. Exposure to renal toxins Stages of CRF 1. Diminished Reserve Volume asymptomatic Normal BUN & Crea, GFR < 10 30% 2. Renal Insufficiency 3. End Stage Renal disease S/Sx: 1.) Urinary System a.) polyuria b.) nocturia c.) hematuria d.) Dysuria e.) oliguria 3.) CNS a.) headache b.) lethargy c.) disorientation d.) restlessness e.) memory impairment 5.) Respiratory a.) Kassmauls resp b.) decrease cough reflex

2.) Metabolic disturbances a.) azotemia (increase BUN & Crea) b.) hyperglycemia c.) hyperinulinemia

4.) GIT a.) n/v b.) stomatitis c.) uremic breath d.) diarrhea/ constipation 6.) hematological a.) Normocytic anemia bleeding tendencies

7.) Fluid & Electrolytes 8.) Integumentary a.) hyperkalemia a.) itchiness/ pruritus b.) hypernatermia b.) uremic frost c.) hypermagnesemia 9.) Cardiovascular changes d.) hyperposphatemia a. HPN e.) hypocalcemia b. CHF f.) met acidosis c. Pericarditis Nursing Mgt: 1. Enforce CBR, reverse isolation 2. Monitor strictly VS, I&O, neurocheck, monitor for signs of hypocalcemia 3. Meticulous skin care. Uremic frost assist in bathing pt 4. Meds: a.) Na HCO3 due Hyperkalemia b.) Kayexelate enema c.) Anti HPN Hydralazine (Apresoline) d.) Vit & minerals (Multivitamins) e.) Phosphate binder (Amphogel) Al OH gel - S/E constipation f.) Decrease Ca Ca gluconate 5. Assist in hemodialysis 1.) Consent/ explain procedure 2.) Weigh patient 3.) Obtain baseline data & monitor VS before and during q30mins, I&O, wt, blood exam 4.) Encourage patient to void 5.) Strict aseptic technique 6.) Monitor for signs of complications: B bleeding (due to heparin) E embolism D disequilibrium syndrome S septicemia S shock decrease in tissue perfusion

76

Disequilibrium syndrome from rapid removal of urea & nitrogenous waste prod leading to: a.) n/v b.) HPN c.) Leg cramps d.) Disorientation e.) Paresthesia Avoid BP taking, blood extraction, IV, at side of shunt or fistula. Can lead to compression of fistula. Maintain patency of shunt by: i. Palpate for thrills & auscultate for bruits if (+) patent shunt! ii. Bedside- bulldog clip - If with accidental removal of fistula to prevent embolism. - Infersole (diastole) common dialisate used 7. Complication - Peritonitis (most feared) - Shock Inflow time: 10-20mins Indwelling time: 30-45 mins 8. Assist in surgery: Renal transplantation : Complication rejection (feared complication). Reverse isolation Rejection time in Acute6mos to 1 year Rejection time in Chronic5-10 years 5. 6.

EYES
External parts 1. Orbital cavity made up of connective tissue protects eye form trauma. 2. EOM extrinsic ocular muscles involuntary muscles of eye needed for gazing movement. 3. Eyelashes/ eyebrows esthetic purposes 4. Eyelids palpebral fissure opening upper & lower lid. Protects eye from direct sunlight Meibomean gland secrets a lubricating fluid inside eyelid b.) Stye/ sty or Hordeolum- inflamed Meibomean gland 5. Conjunctiva 6. Lacrimal apparatus tears Process of grieving a. Denial b. Anger c. Bargaining d. Depression e. Acceptance 2. Intrinsic coat I. sclerotic coat outer most a.) Sclera white. Occupies post of eye. Refracts light rays b.) Canal of schlera site of aqueous humor drainage c.) Cornea transparent structure of eye II/ Uveal tract nutritive care Uveitis infl of uveal tract Consist of: a.) Iris colored muscular ring of eye 2 muscles of iris: 1. Circular smooth muscle fiber - Constricts the pupil 2.radial smooth muscle fiber - Dilates the pupil

2 chambers of the eye 1. Anterior a.) Vitereous Humor maintains spherical shape of the eye b.) Aqueous Humor maintains intrinsic ocular pressure Normal IOP= 12-21 mmHg II. Retina (innermost layer) i. Optic discs or blind spot nerve fibers only No auto receptors cones (daylight/ colored vision) phototopic vision rods night twilight vision scotopic vision = vit A deficiency rods insufficient ii. Maculla lutea yellow spot center of retina iii. Fovea centralis area with highest visual acuity oracute vision Physiology of vision 4 Physiological processes for vision to occur: 1. Refraction of light rays bending of light rays

77

2. Accommodation of lens 3. Constriction & dilation of pupils 4. Convergence of eyes Unit of measurements of refraction diopters Normal eye refraction emmetropia

ERROR of refraction 1. Myopia near sightedness Treatment: biconcave lens 2. Hyperopia/ or farsightedness Treatment: biconvex lens 3. Astigmatisim distorted vision Treatment: cylindrical 4. Prebyopia old slight inelasticity of lens due to aging Treatment: bifocal lens or double vista Accommodation of lenses based on thelmholtz theory of accommodation Near vision = Ciliary muscle contracts= Lens bulges Convergence of the eye: Error: 1. Exotropia 1 eye normal 2. Esophoria 3. Strabismus- squint eye 4. Amblyopia prolong squinting far vision= ciliary muscle dilates / relaxes= lens is flat

corrected by corrective eye surgery

GLAUCOMA increase IOP if untreated, atrophy of optic nerve disc blindness


Predisposing factors: 1. High risk group 40 & above 2. HPN 3. DM 4. Hereditary 5. Obesity 6. Recent eye trauma, infl, surgery Type: 1. 2. 3. S/Sx: 1. 2. 3. 4. 5. 6. 7. Loss of peripheral vision tunnel vision Halos around lights Headache n/v Steamy cornea Eye discomfort If untreated gradual loss of central vision blindness Chronic (open angle G.) most common type Obstruct in flow of aqueous humor at trabecular meshwork of canal of schlema Acute (close angle G.) Most dangerous type Forward displacement of iris to cornea leading to blindness. Chronic (closed angle) - Precipitated by acute attack

Diagnosis: 1. Tonometry increase IOP >12- 21 mmHg 2. Perimetry decrease peripheral vision 3. Gonioscopy abstruction in anterior chamber Nursing mgt: 1. Enforce CBR 2. Maintain siderails 3. Administer meds a.) Miotics lifetime - contracts ciliary muscles & constricts pupil. Ex Pilocarpine Na (Carbachol) b.) Epinephrine eye drops decrease secretion of aqueous humor c.) Carbonic anhydrase inhibitors. Ex. acetapolamide (Diamox) - Promotes increase out flow of aquaeous humor d.) Temoptics (Timolol maleate)- Increase outflow of aquaous humor 4. Surgery: Invasive: a.) Trabeculectomy eyetrephining removal of trabelar meshwork of canal or schlera to drain aqueous humor b.) Peripheral Iridectomy portion of iris is excised to drain aqueous humor Non-invasive: Trabeculoctomy (eye laser surgery)

Nursing Mgt pre op- all types surgery 1. Apply eye patch on unaffected eye to force weaker eye to become stronger.

78

Nursing Mgt post op all types of surgery 1. Position unaffected/ unoperated side - to prevent tension on suture line. 2. Avoid valsalva maneuver 3. Monitor symptoms of IOP a.) Headache b.) n/v c.) Eye discomfort d.) Tachycardia 4. Eye patch both eyes - post op

CATARACT partial/ complete opacity of lens


Predisposing factor: 1. 90-95% - aging (degenerative/ senile cataract) 2. Congenital 3. Prolonged exposure to UV rays 4. DMS/Sx: 1. 2. 3. 4. Loss of central vision - Hazy or blurring of vision Painless Milky white appearance at center of pupil Decrease perception of colors

Diagnosis: Opthalmoscopic exam (+) opacity of lens Nsg Mgt: 1. Reorient pt to environment due opacity 2. Siderails 3. Meds a.) Mydriatics dilate pupil not lifetime Ex. Mydriacyl c.) Cyslopegics paralyzes ciliary muscle. Ex. Cyclogye

4.

Surgery

E extra C - capsular C cataract L - lens E extraction I - intra C - capsular C cataract L - lens E extraction Nursing Mgt:

partial removal of lens

total removal of lens & surrounding capsules

1.Position unaffected/ unoperated side - to prevent tension on suture line. 2.Avoid valsalva maneuver 3.Monitor symptoms of IOP a.) Headache b.) n/v c.) Eye discomfort d.) Tachycardia 4.Eye patch both eyes - post op

RETINAL DETACHMENT- separation of 2 layers of retina


Predisposing factors: 1. 2. 3. 4. 5. S/Sx: 1. 2. 3. 4. 5. Severe myopia nearsightedness Diabetic Retinopathy Trauma Following lens extraction HPN

Curtain veil like vision Flashes of lights Floaters Gradual decrease in central vision Headache

79

Diagnosis- opthaloscopic exam Nursing Mgt: 1. Siderails (all visual disease) 2. Surgery: a.) Cryosurgery b.) Scleral buckling EAR 1. Hearing 2. Balance (Kinesthesia or position sense) Parts: 1.

Outera.) Pinna/ auricle protects ear from direct trauma b.) Ext. auditory meatus has ceruminous gland. Cerumen c.) Tympanic membrane transmits sound waves to middle ear

Disorders of outer ear


Entry of insects put flashlight to give route of exit Foreign objects beans (bring to MD) H2O - drain 2. Middle ear a.) Ear osssicle 1. Hammer -malleus 2. Anvil -Incus 3. Stirrups -stapes

for bone conduction

disorder conductive hearing loss

b. Eustachian tube - Opens to allow equalization of pressure on both ears - Yawn, chew, and swallow Children straight, wide, short c.) Otitis media Adult long, narrow & slanted c. Muscles 1. Stapedius 2. Tensor tympani 3. Inner ear a. Bony labyrinth for balance, vestibule Utricle & succule Otolithe or ear stone has Ca carbonate Movement of head = Righting reflex = Kinesthesia b. Membranous Labyrinth 1. Cochlea ( function for hearing) has organ of corti 2. Endolymph & perilymph for static equilibrium 3. Mastoid air cells air filled spaces in temporal bone in skull Complications of Mastoditis meningitis Types of hearing loss: 1. Conductive hearing loss transmission hearing loss Causes: a.) Impacted cerumen tinnitus & conduction hearing loss- assist in ear irrigaton b.) Immobility of stapes OTOSCLEROSIS d.) Middle ear disease char by formation of spongy bone in the inner ear causing fixation or immobility of stapes e.) Stapes cant transmit sound waves Surgery Stapedectomy removal of stapes, spongy bone & implantation of graft/ ear prosthesis Predisposing factor: 1. Familiar tendency 2. Ear trauma & surgery S/Sx: 1. 2.

Tinnitus Conductive hearing loss

Diagnosis: 1. Audiometry various sound stimulates (+) conductive hearing loss 2. Webers test Normal AC> BC result BC > AC

80

Stapedectomy Nursing Mgt post op 1. Position pt unaffected side 2. DBE No coughing & blowing of nose - Night lead to removal of graft 3. Meds: a.) Analgesic b.) Antiemetic c.) Antimotion sickness agent. Ex. meclesine Hcl (Bonamine) 4. Assess motor function facial nerve - (Smile, frown, raise eyebrow) 5. Avoid shampoo hair for 1 to 2 weeks. Use shower cap

SENSORY NEURAL HEARING LOSS/ NERVE DEAFNESS


Cause: 1. Tumor on cocheal 2. Loud noises (gun shot) 3. Presbycusis bilateral progressive hearing loss especially at high frequencies elderly Face elderly to promote lip reading 4. Menieres disease endolymphatic hydrops f.) Inner ear disease char by dilation of endo lympathic system leading to increase volume of endolin Predisposing factor of MENIERES DISEASE Smoking Hyperlipidemia 30 years old Obesity (+) chosesteatoma Allergy Ear trauma & infection S/Sx: 1. TRIAD symptoms of Menieres disease a.) Tinnitus b.) Vertigo c.) Sensory neural hearing loss Nystagmus n/v Mild apprehension, anxiety Tachycardia Palpitations Diaphoresis

2. 3. 4. 5. 6. 7.

Diagnosis: 1. Audiometry (+) sensory hearing loss Nursing mgt: Comfy & darkened environment Siderails Emetic basin Meds: a.) Diuretics to remove endolymph b.) Vasodilator c.) Antihistamine d.) Antiemetic e.) Antimotion sickness agent f.) Sedatives/ tranquilizers Restrict Na Limit fluid intake Avoid smoking Surgery endolymphatic sac decompression- Shunt

1. 2. 3. 4.

5. 6. 7. 8.

IV NOTES
Clindamycin, KCl===NOT for IV pushit may cause arrhythmia Chloramphenicol===NOT for IM Procaine, Penicillin, Benzatine, Pen G, Vancomycin HCl, Acyclovir (Zovirax) ===NOT for IV Opened bottles must be used in 8 hours Hep Lock- flush with NSS KCl < 80meq/L Epinephrine 1:10,000 Lidocaine- 4 mg /ml (1g/250ml) COMPATIBLE WITH PNSS ONLY Phenytoin Vit K Vit B6

Vit C Hydralazine Furosemide

81

COMPATIBLE WITH D5W ONLY Epinephrine Norepinephrine Ephedrine

Dopamine Dobutamine Nitroprusside NaHCO3

Not to be diluted in LR Penicillin G Ampicillin Cephalosporin NaHCO3 PRBCto be infused within 2-4hours FFP1-1.5 hours Platelet concentrateinfuse immediately and quickly

Pathognomonic sign: Pernicious Anemia- red beefy tongue Carbon monoxide poisoning- cherry red face Addisons Disease- bronze pigmentation of skin Cushings syndrome- buffalo hump Bulimia Nervosa- chipmunk face Liver Cirrhosis- spider angioma & Caput medusae Leprosy- lion face SLE- butterfly rash on face Emphysema- barrel chest Parkinsons pill rolling tremors Myasthenia Gravis- ptosis & Descending paralysis GBS- Ascending paralysis- clumsiness Meningitis- nuchal rigidity. Kernigs & Brudzinskis sign Hypoparathyroidism- Trousseau sign & Chvosteck sign Pancreatitis- Cullens sign & Grey Turners sign DKA- Acetone breath odor & Kussmauls respiration Angina Pectoris- Levines sign Pneumonia- rusty sputum Chronic bronchitis- Blue bloaters Asthma- Pink puffers Appendicitis- rebound tenderness Glaucoma-loss of peripheral vision- Tunnel vision Cataract- Loss of central vision Retinal detachment-Curtain-veil like vision Decreased dopamine- Parkinsons disease Increased dopamine- Schizophrenia Decreased acetylcholine- Myasthenia Gravis / Alzheimer Increased acetylcholine- Bipolar Autoimmune diseases Multiple Sclerosis Myasthenia Gravis GBS

Hypothyroidism Hyperthyroidism Pernicious Anemia

Acute Glomerulonephritis

Apparatus needed at bedside: Acetaminophen toxicity- Acetylcisteine. Prepare suction apparatus-acetylcysteine causes outpouring of secretions. Myasthenia Gravis- tracheostomy set. For respiratory arrest. Hemodyalisis- bulldog clip Senkstaken tube- scissors to deflate balloon. Guillain Barre Syndrome- tracheostomy set. For respiratory arrest. Convulsion- suction apparatus. Increased secretions. Hyperthyroidism- tracheostomy set. For laryngeal spasm post subtotal thyroidectomy complication. Goiter- tracheostomy set. For laryngeal spasm post subtotal thyroidectomy complication. Hypoparathyroidism- tracheostomy set. For laryngeal spasm. Isolation precautions: Cushings synd reverse isolation - due to increased corticosteroid in body. Aplastic anemia reverse isolation - due to bone marrow depression. Cancer any type reverse isolation immunocompromised. Post liver transplant reverse isolation takes steroids lifetime. Prolonged use steroids reverse isolation Meningitis strict respiratory isolation safe after 24h of antibiotic therapy TB- strict respiratory isolation

82

You might also like