Professional Documents
Culture Documents
1. IDENTIFICATION OF THE SUBSTANCE OR PREPARATION AND THE COMPANY/UNDERTAKING Product label name Monochloroacetic acid, 80% solution in methanol Supplier Akzo Nobel Industrial Chemicals B.V. Stationsstraat 77 PO Box 247 NL-3800 AE Amersfoort Tel.: +31-334676767 E-mail address of person responsible for safety data sheet basechemicals.sds@akzonobel.com Emergency telephone T +31570679211 F +31570679801 AkzoNobel Chemicals-Deventer-NL Intended use Chemical intermediate for the chemical industry Date of last issue / Revision number 2009/02/05 / 10.04 2. HAZARDS IDENTIFICATION Flammable. Toxic by inhalation, in contact with skin and if swallowed. Causes burns. May cause sensitization by skin contact. Harmful: may cause lung damage if swallowed. Very toxic to aquatic organisms. 3. COMPOSITION/INFORMATION ON INGREDIENTS This product is to be considered as a preparation in conformance to EC directives Information on hazardous ingredients Chemical description Monochloroacetic acid, 80% solution in methanol Composition / information on ingredients Number
1 2 3
% w/w
30 3 58
CAS-number
000079-11-8 000067-56-1 000096-34-4
Chemical name
Chloroacetic acid Methanol Methyl chloroacetate
Annex-1 number
1 2 3 607-003-00-1 603-001-00-X 607-205-00-X
EC-number
201-178-4 200-659-6 202-501-1
Risk-phrase(s)
R25 R34 R50 R11 R23/24/25 R39/23/24/25 R10 R23/25 R37/38 R41
4. FIRST AID MEASURES Symptoms and effects MCA solution (even at low concentration) is rapidly absorbed through the skin even if there are no visible lesions. Contamination of the skin may lead to serious systemic effects with symptoms like vomiting and/or shock resulting in a highly serious and potentially fatal intoxication, especially if decontamination is delayed. Toxic by inhalation, in contact with skin and if swallowed. Corrosive to eyes, skin and upper respiratory tract. Date of last issue 2009/02/05 Product code 722191 Page 1 - 8 Date of printing/pdf file generated 2009/02/16 GB-The Netherlands
Chloroacetic acid
skin (private grenswaarde) Time Weighted Average (TWA) (private grenswaarde) 4 mg/m Can be absorbed through skin.
Methanol
Ontwikkeling risico categorie skin (private grenswaarde) Short Term Exposure Limit (STEL) (private grenswaarde) Time Weighted Average (TWA) (private grenswaarde) skin (wettelijke grenswaarde) Short Term Exposure Limit (STEL) (wettelijke grenswaarde) 520 mg/m 520 mg/m 260 mg/m Can be absorbed through skin. May cause harm to the unborn child. Can be absorbed through skin.
Methyl chloroacetate
Time Weighted Average (TWA) (private grenswaarde) 5 mg/m
9. PHYSICAL AND CHEMICAL PROPERTIES Appearance liquid Colour colourless Odour acidic, pungent odour threshold: 0.045 ppm Boiling point/range 101 C Melting point/range -15 C ( Crystallization point/range ) Flash point 55 C ( Pensky-Martens, closed cup ) Flammability Flammable Explosive properties Above the flash point an explosive mixture can be formed Oxidising properties not available Vapour pressure 1.89 kPa (20 C) 10.42 kPa (50 C) Density 1250 kg/m (20 C) Bulk density not applicable Solubility in water 7.7% ( Measured after 5 minutes) Solubility in other solvents not available pH value 0.5 ( 20 C) Partition coefficient n-octanol/water not available Relative vapour density (air=1) not available Viscosity 2.1 mPa.s (20 C) 1.4 mPa.s (40 C)
Acute toxicity Oral LD50 rat : 150 mg/kg ( Toxic if swallowed ) ( Akzo Nobel E-file ) Dermal LD50 rat: 127 mg/kg ( Toxic in contact with skin ) ( Akzo Nobel E-file ) Irritation Skin Causes severe burns ( rabbit ) ( Akzo Nobel E-file ) Eye Risk of serious damage to eyes ( rabbit ) ( Akzo Nobel E-file ) Sensitization May cause sensitization by skin contact ( guinea pig ) ( Akzo Nobel E-file ) Genotoxicity Ames test: Not mutagenic Other toxicological information Product is absorbed readily through the skin and may cause toxic effects. 12. ECOLOGICAL INFORMATION
Monochloroacetic acid, 80% solution in methanol
Ecotoxicity fish Acute toxicity, 96h-LC50 ( Danio rerio ): 1.13 mg/l daphnia Acute toxicity, 24h-EC50 ( Daphnia magna ): 5.5 mg/l algae Acute toxicity, 96h-EC50 (Selenastrum capricornutum): 0.25 mg/l
Sea transport (IMO / IMDG-code) Class 6.1 Packing group II UN number 2927 EMS F-A, S-B Marine pollutant no
Air transport (ICAO-TI / IATA-DGR) UN number 2927 Class 6.1 Packing group II Proper Shipping Name TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (Monochloroacetic acid, 80% solution in methanol) Other information CORROSIVE risk label required additionally 15. REGULATORY INFORMATION Product label name Monochloroacetic acid, 80% solution in methanol Labelling according to EC directives EC-number not applicable Classification based on Annex-1 / Calculation
Description
Flammable Toxic by inhalation, in contact with skin and if swallowed Causes burns May cause sensitization by skin contact Very toxic to aquatic organisms Harmful: may cause lung damage if swallowed
Description
Do not breathe fumes/vapour Avoid contact with skin Wear suitable protective clothing, gloves and eye/face protection In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Avoid release to the environment. Refer to special instructions/Safety data sheets
D F
If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label
German Water Hazard Class (WGK) 2 (VwVwS Anhang 4 Nr. 3) 16. OTHER INFORMATION
Methyl chloroacetate
Revision 10.04 Composed by Dr. P. Thomas Ing. J.G.M. van der Helm Changes were made in section 1
This information only concerns the above mentioned product and does not need to be valid if used with other product(s) or in any process. The information is to our best present knowledge correct and complete and is given in good faith but without warranty. It remains the user's own responsibility to make sure that the information is appropriate and complete for his special use of this product.