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1. Family History of Stroke among Mexican-American and Non-Hispanic White Patients with Stroke and
TIA: Implications for the Feasibility and Design of Stroke Genetics
Research....................................................... 1
13 May 2014 ii ProQuest
Document 1 of 1

Family History of Stroke among Mexican-American and Non-Hispanic White Patients with Stroke and
TIA: Implications for the Feasibility and Design of Stroke Genetics Research
Author: Lisabeth, Lynda D; Sharon L.R. Kardia; Smith, Melinda A; Fornage, Myriam; Morgenstern, Lewis B

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Abstract: Family history of stroke may differ by ethnicity. This study examined the associations of ethnicity and
stroke risk factors with family history of stroke using data from the Brain Attack Surveillance in Corpus Christi
Project. A random sample of stroke/transient ischemic attack cases was interviewed about family history of
stroke (n = 524). Thirty-six percent of the cases reported a family history of stroke, with 26% reporting a
parental and 13% a sibling history. Compared to non-Hispanic whites (NHWs), Mexican-Americans (MAs) were
two times (OR = 2.07; 95% CI: 1.09-3.95) more likely to have a sibling with stroke. More MAs (8.1%; 95% CI:
4.6-11.6) had living siblings with stroke compared to NHWs (1.9%; 95% CI: 0.1-3.8). Since MAs are more likely
to have living siblings with stroke compared with NHWs, MAs may be a more feasible population for family
stroke studies than predominantly white populations.
Copyright 2005 S. Karger AG, Basel
MeSH: Aged, Blood Donors, Cluster Analysis, Epidemiologic Methods, European Continental Ancestry Group,
Family, Feasibility Studies, Female, Humans, Male, Mexican Americans, Middle Aged, Research Design, Risk
Factors, Sex Factors, Ischemic Attack, Transient -- epidemiology (major), Ischemic Attack, Transient -- genetics
(major), Stroke -- epidemiology (major), Stroke -- genetics (major)
Publication title: Neuroepidemiology
Volume: 24
Issue: 1-2
Pages: 96-102
Publication year: 2005
Publication date: 2005
Year: 2005
Publisher: S. Karger AG
Place of publication: Basel
Country of publication: Switzerland
Publication subject: Medical Sciences--Psychiatry And Neurology
ISSN: 02515350
Source type: Scholarly Journals
Language of publication: English
Document type: Comparative Study
Accession number: 15459516
ProQuest document ID: 232973924
Document URL: http://search.proquest.com/docview/232973924?accountid=50673
13 May 2014 Page 1 of 2 ProQuest
Copyright: Copyright (c) 2005 S. Karger AG, Basel
Last updated: 2014-04-29
Database: ProQuest Medical Library,ProQuest Psychology Journals
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