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Introduction to Cell and Molecular Biology, Biol&222

Fall 2013
LECTURE Sections A&B
Building 15, Room 320; M,T, Th 8:00 9:20
LAB:
Section A(5105): Building 15, Room 320L; Wednesday 8:00 10:20
Section B(5106): Building 15, Room 320L; Friday 8:00 10:20
Instructor
Kim Harrington (you can call me Kim or Mrs. Harrington or Your Majesty Professor Harrington)
Office Building 15 (The Science and Engineering Building) Room 237

Contact Information
Telephone: 253-460-4305
Email: kharrington@tacomacc.edu

Office Hours
M 9:30 11:30 Building 15 Rm. 237 (My office)
T 9:3011:00 Building 15 Rm. 237 (My office)
Th 9:3011:00 Building 15 Rm. 237 (My office)

I welcome you to see me during my office hours. I am also usually happy to see you at other times,
though sometimes I will have to ask you to see me at another time. You can also make an
appointment to see me. If you are not on campus, you can make an appointment via email or phone
message for a time in which we can have a phone conversation.

Catalog Description
Introduction to the structures and functions of biological molecules; anatomy of prokaryotic and
eukaryotic cells; cell metabolism and metabolic diversity; molecular genetics and genomics. Laboratory
included.

Prerequisites
BIOL& 160 and CHEM& 161

Course Overview
Biology is incredibly exciting because it affects every aspect of our lives! I hope this class will
help you to understand how your body and the things around you work. I hope it will help you to
make better decisions. I hope you will get as excited about biology as I am! Oh, and I hope that you
will have the foundation information that you will need in other classes mastered so that you ace them
like I hope you ace this class.

Degree Learning Outcomes
Core of Knowledge (COK): Demonstrate a basic knowledge of each of the distribution areas
(Written Communication, Humanities, Quantitative Skills, Natural Sciences and Social Sciences;
or, as applicable, specific professional/technical programs), integrate knowledge across
disciplines, and apply this knowledge to academic, occupational, civic and personal endeavors.
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Communication (COM): Listen, speak, read, and write effectively and use nonverbal and
technological means to make connections between self and others.
Critical Thinking & Problem Solving (CRT): Compare, analyze, and evaluate information and
ideas, and use sound thinking skills to solve problems.
Information & Information Technology (IIT): Locate, evaluate, retrieve, and ethically use
relevant and current information of appropriate authority for both academic and personal
applications.
Living & Working Cooperatively/Valuing Differences (LWC): Respectfully acknowledge
diverse points of view, and draw upon the knowledge and experience of others to collaborate in a
multicultural and complex world.
Responsibility & Ethics (RES): Demonstrate an understanding of what constitutes responsible
and ethical behavior toward individuals, the community, and the environment.

Program Learning Outcomes Natural Sciences
Upon successful completion of the Natural Sciences distribution requirements for the AAS Option A or
B, or the Associate in Biology, or the Associate of Sciences degrees, students will:
1. Evaluate information scientifically in the context of his/her own life
2. Explain the importance of observation and hypothesis testing in the scientific process, and
distinguish between the scientific process and other human endeavors
3. Communicate the primary principles and processes underlying at least one natural system (for
example: atoms and molecules, cells and organisms, the oceans and atmosphere, the solid earth, or
the cosmos)
4. Perform and effectively communicate the results of scientific investigations, and explain how
research is done in science
5. Demonstrate the safe and proper use of scientific instrumentation, measuring devices, chemical
reagents, media, and/or other tools of science in a laboratory or field setting relevant to specific
disciplines of science

Course Learning Objectives
Upon successful completion of this course, the student should be able to:
1. Demonstrate the process of scientific inquiry. PLO: 1, 2, 3, 4
2. Differentiate between primary, peer-reviewed sources, reputable secondary sources, and
questionable sources. PLO: 4
3. Create accurate, clearly communicated and properly cited summaries of scientific information.
PLO: 4
4. Use scientific databases to gather biological information. PLO: 4,
5. Demonstrate laboratory and/or field skills related to the content of this course. PLO: 1, 2, 3, 4
6. Relate historically important milestones to our ongoing understanding of biological concepts
and principles relevant to this course. PLO: 2, 3,
7. Integrate biological concepts across levels of organization from molecules to ecosystems.
PLO: 3,
8. Interpret models used to visualize molecular, cellular, physiological and ecological
phenomena. PLO: 3, 4,
9. Illustrate the structures of proteins, carbohydrates, lipids and nucleic acids. PLO: 3,
10. Correlate the structures of macromolecules to their properties and functions. PLO: 3,
11. Differentiate between noneukaryotic and eukaryotic cells in terms of their structures and
functions. PLO: 3,
12. Explain the detailed cellular functions and their interactions in: signal transduction, DNA
replication, the cell cycle and cell division, meiosis, Mendelian and chromosomal inheritance,
gene expression, cellular respiration and photosynthesis. PLO: 3,
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13. Detail the mechanisms that control the expression of genes. PLO: 3,
14. Explain the techniques of biotechnology and the contexts in which they are used. PLO: 1, 3
15. Apply the principles of thermodynamics and reaction kinetics to enzyme mediated processes.
PLO: 3
16. Explain how comparative genomics contributes to the understanding of evolutionary
relationships between organisms. PLO: 3

Instructional Methods Used
This course utilizes a combination of lecture, laboratory exercises, small group discussions and
activities and online assignments.

Academic Assistance
I am one of many resources available to help you succeed in this class. Here are some other resources.

Study Group
You should join or form a small study group for this class. A study group is an excellent source of
help.
Tutoring Center
Biology tutors are available at no additional cost in the Tutoring Center on the second floor of
building 7. Appointments can be made in person or by calling 253.566.6032. For more
information see: http://www.tacomacc.edu/resourcesandservices/writingandtutoringcenter/

Counseling Center
The Counseling Center staff in Building 7 can help you address personal difficulties that interfere
with your studies. This includes things like test anxiety. Call 253.566.5122 to make an
appointment. http://www.tacomacc.edu/resourcesandservices/counseling/

Laboratory
All students must follow the biological science lab safety procedures and standard operating
procedures established by Tacoma Community College, the Science & Engineering Department, and
the instructor. Students who repeatedly or willfully violate these procedures may face sanctions,
including removal from the course, a failing grade, and referral to the college for action under the
Code of Student Rights and Responsibilities. The departmental safety procedures for biological
science are available at: Microbiology Safety Guidelines

Textbooks & Supplemental Materials
Required Textbook: Neil A. Campbell, Jane B. Reece, Lisa A. Urry, Michael L. Cain,
Steven A. Wasserman, Peter V. Minorsky, and Robert B. Jackson. 2011. Biology ninth
Edition. San Francisco, CA: The Benjamin Cummings Publishing Co., Inc. If you did
not purchase your textbook at the TCC bookstore, you must also purchase the
Mastering Biology access codes.

A thread-bound journal that is 10X 7 1/8 or 9 3/4 X 7 . It can be either
composition style or quad-ruled, whichever you are most comfortable with.

Technology
MasteringBiology is an online tutorial and homework program that accompanies your textbook and
will be utilized in this course.
The course is web enhanced in Canvas.

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Evaluation Criteria & Grading Standards
Grading will NOT be on a curve. You will be graded according to how well you demonstrate your
understanding of the material taught in this course. This means that you are not competing against each
other for a few A's. Instead, you should help each other learn the material. You are each other's best help.

The final grade will be determined as follows.
Homework (approximately) 170 points
Final Exam 120
Exam 5 @ 70 points each (drop one) 280
Lab notebook 64
Journal Club 66
Poster 50

Note: The number of assignments and points for an assignment may change. This will result in a
change in the total points.

The course grade will be determined from the percentage of the possible points earned using the table
below. As described in the Quizzes and Exams section, the lowest quiz score is not included in the
course grading. You can calculate your current grade at any time calculating your percentage earned:
100
far so possible s int po total
earned have you s int po total


The grade will be based on a percentage of the total points earned, using the following table:

GRADE PERCENTAGE GRADE POINTS
A 93-100 4.0
A- 90-92 3.7
B+ 87-89 3.3
B 83-86 3.0
B- 80-82 2.7
C+ 77-79 2.3
C 73-76 2.0
C- 70-72 1.7
D+ 67-69 1.3
D 63-66 1.0
E 0-59 0.0

Exam dates are on your schedule. The lowest exam score (or one that you missed) is dropped and does
not count toward the final course grade. (If an exam receives a grade penalty due to academic
dishonesty it will be included in the final course grade. This exam will not be included when
determining which exam scores are dropped.) Exams may include questions about the laboratory
experiments. Exams may be cumulative. There are no make-up exams.

A two hour final exam is given. The exam may include questions about the laboratory. The exam is
cumulative. Only exams missed due to dire emergency may be made up or taken early. I must be
notified before the missed exam. Travel is not a dire emergency. Do not schedule travel on exam
dates. The exam date is listed on the Course Calendar.

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Homework
Mastering Biology
Most of the homework is at the MasteringBiology web site. You are responsible for making sure
that you leave plenty of time to allow for technical or computer difficulties and still complete
your assignments on time. The due date will not be extended due to internet, portal or other
technical issues. You do not lose any points for looking at hints, but you get extra points for not
looking at hints. You do lose parts of points for guessing the answer and getting it wrong. You
also lose 20% of the possible points per day after the due date up to 50% of the point value. If
you score lower than 95% of the initial assignment, you will be given additional work to help you
learn the material. These are worth additional points.

Journal Club
You will prepare a journal club presentation on your article and present it to your lab section.
You will also read and prepare a brief analysis of the papers that others present.

Poster
A poster will be prepared and presented according to the rubric found in Canvas. This is a
scientific poster presenting the research done in the lab.

Withdrawals and Incompletes
Please see the calendar of important dates. http://www.tacomacc.edu/areasofstudy/academiccalendar/

Attendance
Successful completion of this course will require perfect or near-perfect attendance. Students will be
responsible for all the material that is presented during lecture and laboratory sessions. A missed lab
cannot be made up and all lab quizzes, exams and assignments cannot be made up. A missed exam
cannot be made up. Late assignments will not be accepted without advance approval.

Student Requirements

Academic Dishonesty
As stated in the TCC Catalog, Students are expected to be honest and forthright in their
academic endeavors. Cheating, plagiarism, fabrication or other forms of academic dishonesty
corrupt the learning process and threaten the educational environment for all students (pg. 31).

In this course, sanctions for academic dishonesty will be as follows:
No dishonorable conduct will be tolerated. Any form of academic dishonesty on quizzes / assignments
will result in a 0 grade for that assignment / quiz. Other forms of dishonesty or misconduct will also result
in a 0 grade. Second offenses of any type of academic dishonesty will result in an E for the course and the
student is asked to not return to class. Dishonorable conduct includes:
Cheating (to violate rules): Honesty is expected in all endeavors.
Plagiarism (to present the ideas or words of another as ones own or to not properly cite a source
when using adapted words or ideas): Tables, figures and words should never be copied directly
from a book, Internet, another students paper or any other works.
Lying (to be untruthful or false): There is no reason to lie to an instructor. Be truthful and take
responsibility for your own actions.
Stealing (to take and carry away without permission): Permission is required to borrow any
materials from the classroom.
Other violations: A student that is in violation of any college policies or other forms of
dishonesty/conduct will be asked to leave the class upon the first offense, will lose all points for that
period and will be reported to the Associate Vice President for disciplinary proceedings. The complete
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Administrative Procedure for Academic Dishonesty is available on the TCC website at:
http://www.tacomacc.edu/abouttcc/policies/administrativeprocedureforacademicdishonesty/

Accommodations
Students with Special Needs: All students are responsible for all requirements of the class, but
the way they meet these requirements may vary. If you need specific auxiliary aids or services
due to a disability, please contact the Access Services office in Building 18 (253-566-5328).
They will require you to present formal, written documentation of your disability from an
appropriate professional. When this step has been completed, arrangements will be made for you
to receive reasonable auxiliary aids or services. The disability accommodation documentation
prepared by Access Services must be given to me before the accommodation is needed so that
appropriate arrangements can be made.
http://www.tacomacc.edu/resourcesandservices/accessservices/

Classroom policies (as applicable)
Children/visitors in Class: Only students that are enrolled in the class may attend on a regular
basis. There are some instances that I will allow visitors. However, you must get permission from
me at least one day before bringing a visitor into the classroom.
Cell Phones and Pagers: These must be on vibrate if present in the classroom. Please remove
yourself from the classroom before using such a device during breaks, before class and after
class. No text messaging is allowed during class.
Electronic Dictionaries/translators: These devices are not allowed in the classroom. It is your
responsibility to learn the needed vocabulary and be able to apply it. English is the primary
language used in this class and everyone is expected to write, speak, and understand English. A
grade of B or above in English 91 is recommended.

Classroom Etiquette
Students come to class to learn. It is expected that everyone will act in ways that are respectful and
that promote learning for all students and will refrain from actions that interfere with learning.
Specific examples include

Arrive on time. If you arrive late, do your best to minimize the disruption to other students. If I
will be late, I will send someone to inform you. Use the time to study. If late arrivals become a
problem, I will close and lock the door ten minutes into class and not allow anyone to enter
after that point.
Be ready to learn when the class begins. Even quiet conversation is very disruptive during class.
If you cannot hear what is said or see what is written on the board, let me know.
Stay until the end of class. If you must leave early, sit near the exit and minimize the disruption to
other students.
Learn the names of the people you interact with in class and lab.
Guests, including children, are welcome in class on an occasional basis with my prior approval.
Guests must not disrupt the class in any way. You are responsible for your guests. Guests are not
allowed in the lab.
Turn off all alarms and ringers before class starts.
Beverages are allowed in a classroom. Food should generally not be eaten in the classroom,
except as necessary to maintain your health. Food and beverages are not permitted in the lab
rooms.
If you have a contagious illness, stay home.
I can usually answer a few quick questions before and after class. However, lengthy discussions,
and confidential or private discussions should take place during office hours or by special
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appointment.

Etiquette for Classroom Dispute Resolution
If you have questions or concerns about this class or me, please come to talk with me about your
concerns. If we are unable to resolve your concerns, you may talk next with the Chair of the
Program/Department, Rebecca Sliger, 253-460-4428. The Chair can assist with information
about additional steps, if needed.


Caveats
This syllabus and schedule are subject to change in the event of extenuating circumstances. If
you are absent from class, it is your responsibility to check for announcements made while you
were absent.

Schedule
Date Day Details
Sep 23 Mon
Macromolecules
12am

Sep 24 Tue
COMGEN
12am

Sep 25 Wed
Lab 1A: Sequence Data Analysis
12am

Sep 26 Thu
Cells
12am

Sep 27 Fri
Lab 1B: Sequence Data Analysis
12am

Sep 29 Sun
Due MB 5,6,7 (41)
12am

Sep 30 Mon
Membranes
12am

Oct 1 Tue
Membranes cont.
12am

Oct 2 Wed
Lab 2A: Techniques
12am

Oct 3 Thu
Exam 1
12am

Oct 4 Fri
Lab 2B: Techniques
12am

Oct 6 Sun
Due MB 16 (11)
12am

Oct 7 Mon
DNA
12am
Project Background Due
12am

Oct 8 Tue
DNA
12am

Oct 9 Wed
Lab 3A: Gel
12am

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Date Day Details
Oct 10 Thu
Translation
12am

Oct 11 Fri
Lab 3B: Gel
12am

Oct 13 Sun
DUE MB 17(18)
12am

Oct 14 Mon
Translation
12am

Oct 15 Tue
Regulation of Gene Expression
12am

Oct 16 Wed
Lab 4A: Culture
12am

Oct 17 Thu
Regulation of Gene Expression
12am

Oct 18 Fri
Lab 4B: Culture
12am

Oct 20 Sun
DUE MB 18 (7)
12am

Oct 21 Mon
EXAM 2
12am

Oct 22 Tue
Educational Planning Day - No Class
12am

Oct 23 Wed
Lab 5A: DNA Isolation
12am

Oct 24 Thu
Biotechnology
12am

Oct 25 Fri
Lab 5B: DNA Isolation
12am

Oct 28 Mon
Biotechnology
12am

Oct 29 Tue
Biotechnology cont.
12am

Oct 30 Wed
Lab 6A: DNA Quality
12am

Oct 31 Thu
Genomes
12am

Nov 1 Fri
Lab 6B: DNA Quality
12am

Nov 3 Sun
DUE MB 20,21(11)
12am

Nov 4 Mon
Genomes
12am

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Date Day Details
Nov 5 Tue
EXAM 3
12am

Nov 6 Wed
Lab 7A: Sequencing
12am

Nov 7 Thu
Signalling
12am

Nov 8 Fri
Lab 7B: Sequencing
12am

Nov 10 Sun
MB 11,12,13 (24)
12am

Nov 11 Mon
Veteran's Day - No Class
12am

Nov 12 Tue
Mitosis
12am

Nov 13 Wed
Lab 8A: Sequence Cleanup
12am

Nov 14 Thu
Meiosis
12am

Nov 15 Fri
Lab 8B: Sequence Cleanup
12am

Nov 17 Sun
MB 14,15 (18)
12am

Nov 18 Mon
Inheritance
12am
Materials and Methods Due
12am

Nov 19 Tue
Inheritance cont.
12am

Nov 20 Wed
Lab 9A: Bioinformatics/Poster
12am

Nov 21 Thu
EXAM 4
12am

Nov 22 Fri
Lab 9B: Bioinformatics/Poster
12am

Nov 24 Sun
MB 8 (10)
12am

Nov 25 Mon
Metabolism
12am

Nov 26 Tue
Cellular Respiration
12am

Nov 27 Wed
Thanksgiving - No Lab
12am

Nov 28 Thu
Thanksgiving - No Class
12am

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Date Day Details
Nov 29 Fri
Thanksgiving - No Lab
12am

Dec 1 Sun
MB 9,10 (25)
12am

Dec 2 Mon
Cellular Respiration
12am

Dec 3 Tue
Photosynthesis
12am

Dec 5 Thu
EXAM 5
12am

Dec 12 Thu
Final Exam