DRUG RESIDUES

BetaStar Products FOR INTERNAL

USE ONLY
Overview:
• Antibiotics have been used in cows for many years to treat such common infectious diseases as
mastitis. The past several years has seen increased pressure on milk producers to increase milk
production from each and every cow. This pressure often results in more infections, and the
increased use of antibiotics to counter these infections. Treated cows must be quarantined for a
number of days, depending on the antibiotic used (typically 4-5 days), to allow the drug to clear
the cow’s system. If this quarantine period is inadequate, antibiotics can be passed into milk
intended for consumers—and result in potentially severe penalties and other consequences.
• Neogen's BetaStar testing products detect the b-lactam group of antibiotics (e.g., penicillin,
ampicillin, amoxicillin, cefapirin, and ceftiofur). The b-lactam group is responsible for approxi-
mately 95% of all milk antibiotic contamination.
• The rapid BetaStar tests are available in a simple format that requires only an incubator, and a
laboratory based format for processing larger amounts of samples.

Why buy Neogen’s BetaStar kits?

Neogen offers the quickest time to result with a very easy to use and interpret test device—and BetaStar is sup-
ported by a well-trained sales force with 24-hour customer service.

Neogen’s Product Line Tolerances (ppb)

• BetaStar 25: contains 25 test vials with lyophilized receptor,
25 test strips, 1 syringe, and 25 tips. Requires incubator set at
47.5°C.
• BetaStar 250: contains 250 test vials with lyophilized receptor,
250 test strips. This format is suitable for large scale laborato-
ries. Requires incubator set at 47.5°C.
• BetaStar 100: contains 2 vials with lyophilized receptor,
enough for 100 tests, and 4 containers with 25 test strips
each. This format is suitable for larger amounts of samples as
it requires some preparation of receptor solution and pipet-
ting into Eppendorf tubes. Requires incubator set at 47.5°C,
pipettor and tips for 25, 100, and 1,350 µL transfers, and 100
Eppendorf 1.5 mL conical tubes.
Neogen’s Competitive Advantages
• Quickest. Requiring only 5 minutes to result, BetaStar is the
quickest dairy antibiotic test available.
• Highly sensitive. The high sensitivity to b-lactams makes it
a reliable and efficient test which can be used on the farm,
tanker, or in the laboratory.
• Simple. No special training required, and contains all the
reagents needed. Interpretation of test results is simple and
unambiguous.
• Reliable. Extending incubation beyond 5 minutes will not
compromise the test result. The BetaStar test stick will not
fade, and can be kept for future reference.
• Supported. Free training, knowledgeable sales and around-
the-clock technical support. In-house R & D staff.
US EU
Penicillin 5 4
Ampicillin 10 4
Amoxicillin 10 4
Cefapirin 20 10
Ceftiofur 100 100
Description Item
ROW (Rest of World)
BetaStar 25 Kit..................................... BKB002
BetaStar 100 Kit................................... BKB001
BetaStar 250 Kit................................... BKB014
North America
BetaStar 25 Kit..................................... BKB102
BetaStar 100 Kit................................... BKB101
BetaStar 250 Kit................................... BKB114
BetaStar Positive Controls.................... BT1L13
BetaStar Strip Reader............................... 73500
BetaStar Heat Block............................... 602372
BetaStar Strip Reader Version II............. XXXX
Approvals
BetaStar.................................................................. AFNOR
Competitive Products
(For a complete discussion of competitive products, see the
Competitive Folder in Tech Data)

Charm Sciences, Inc.

Lawrence, MA • www.charm.com
1. Charm ROSA (rapid one-step assay) SL-6. One-step
test that uses the same dipstick technology as BetaStar
that detects all 6 US-required b-lactam drugs. FDA ap-
proved.
2. Charm ROSA MRL. One-step test that uses the same
dipstick technology as BetaStar to specifically match the
European Union Maximum Residue Limits.
Neogen’s advantages
• Time to result for ROSA tests is slower (8 minutes).
• ROSA tests are difficult to read visually.
• ROSA’s incubations are time sensitive.
• Poor traceability as lines fade over time.

Idexx Laboratories, Inc.

Westbrook, Maine • www.idexx.com
1. SNAP Beta-Lactam. Simliar to BetaStar in detection of
b-lactams. With separate cartridges can also detect tetra-
cylines, sulphonamides, and gentamicin. FDA approved.
Neogen’s advantages
• Time to result for SNAP is slower (8 minutes).
• SNAP is difficult to read visually.
• SNAP’s incubation is time sensitive.
• Poor traceability as lines fade over time.

Unisensor
Belgium • www.unisensor.be
1. Twinsensor. Detects b-lactams and tetracylines together
in only 1 operation. Visual reading or optical measure-
ment with Readsensor.
Neogen’s advantages
• Time to result for Twinsensor is slower (6 minutes).
• Twinsensor is difficult to read visually.
• Twinsensor has a gradula titration curve, and fixed refer-
ence line.

FOR INTERNAL USE ONLY Quick Ref Sell Sheet: BetaStar 1206