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17
PHARMACY PREP

PSYCHOSIS

1-A schizophrenic patient is stabilized on haloperidol, but cannot tolerate the drugs side
effects. His physician changes his medication to risperidone. All of the following parameters
should be monitored EXCEPT:
a) Symptoms
b) EPS
c) Plasma levels of risperidone
d) Blood pressure
E-Weight gain
Ans: C
Tips: Drug plasma levels are monitored for those drugs that have narrow therapeutic index,
examples: warfarin, lithium, digoxin, phenytoin, theophylline, and Amiodarone

2-Which of the following statements about clozapine is/are TRUE?
I. It is used as a first line therapy in the treatment of psychosis
II. It is used in refractory patients
III. Patients must agree to carry out weekly blood tests while being treated with the drug
a) I only
b) III only
c) I and II only
d) II and III only
e) All of the above
Ans: D
Tips: Because of a high risk of agranulocytosis, clozapine is reserved for refractory patients
who do not respond to other first line drugs.

3. What factors would you consider when you select an antipsychotic drug?
I-Side effect profile
II-Past medical history of patient
III- Availability of dosage forms
a) I only
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PharmacyPrep.

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b) III only
c) I and II only
d) II and III only
e) All of the above
Ans-

4. Which medication does not require any counter checking of pharmacist for disposal?
I-Clozapine
II-Narcotic medication
III-Benzodiazepine
a) I only
b) III only
c) I and II only
d) II and III only
e) All of the above
Ans-A
Tips: clozapine is a schedule I prescription drug does not require checking for pharmacist for
disposal

5-In schizophrenic patient with Alzheimer and Parkinson disease haloperidol is the drug of
choice. Because haloperidol:
A-Is high potent neuroleptic with less extrapiramidal effect
B-Is high potent neuroleptic with less anticholinergic effect
C-Is high potent neuroleptic with less sedation
D-Is least potent neuroleptic with high extrapyramidal side effects
E-Is least potent neuroleptic with high anticholinergic effect

6. The goal of therapy with respect to Bipolar disorder is/are:
I Prevent recurrence
II Control symptoms of acute episodes
III Prevent psychosis
(A) I only
(B) III only
(C) I and II
(D) II and III
(E) All of the above
Answer: (C)
Reference: Therapeutic Choices 5
th
edition Page 79

7. All true for a woman who is pregnant with Bipolar Disorder EXCEPT:
(A) Untreated woman will not result in harm of child
(B) Untreated woman are susceptible to postpartum depression
(C) Women with bipolar disorder are able to manage pregnancy
(D) Collaborative management of the pregnancy by a psychiatrist, an obstetrician and a family
physician is recommended.
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Copyright 2000-2010 TIPS Inc. Unauthorized reproduction of this manual is strictly prohibited and it is
illegal to reproduce without permission. This manual is being used during review sessions conducted by
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(E) If medication is to be discontinue prior to pregnancy, it should be tapered with medical
supervision
Answer: (A)
Reference: Therapeutic Choices 5
th
edition Page 86