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SEDDS/SMEDDS:-
of
The
various
ways
characterize
SEDDS
compiled below.
to
are
emulsification
identified.[1]
can
be
7. Liquification time.
It is estimated time required by
solid SEDDS to melt in vivo in
absence
of
agitation
to
simulated GI condition. One
dosage form is covered in a
transparent polyethylene film
and tied to the bulb of a
thermometer by means of a
thread. The thermometer with
attached tablets is placed in a
round bottom flask containing
250 ml of simulated gastric
fluid without pepsin maintained
at
37
18C. The time taken for
liquefaction is subsequently
noted.[1]
8. Conductivity measurement.
It is able to determine the point
of aqueous phase addition
where system changes from oil
continuous
to
aqueous
continuous phase.[2]
Branded
technology
SEDDS/SMEDDS:-
for
Reference:1.
2.