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Culture Documents
the respiratory tract, is often an indication of the type of respiratory disease that gives rise to sputum
production. By examining the type of sputum and noting the color as well as the presenting signs and
symptoms, a differential diagnosis may be reached prior to laboratory tests and examination sputum
cytology and culture. A thorough case history and complete physical examination is also necessary.
Ideally, the morning sputum specimen should be examined as this provides a more vivid indication of
the cause. Sputum samples that are coughed or spat up during the course of the day may lack the
features that would provide a clue to the disease process and be tainted by foods and drinks, especially
those rich in artificial colorants.
Clear
White
Gray
Yellow
Green
Brown
Pink
Red
Rust-colored
Black
Object 1
Pulmonary edema (fluid in the lungs) clear, white or pink frothy sputum
Viral respiratory tract infections clear to white (acute)
Chronic bronchitis (COPD) clear to gray
Asthma white to yellow (thick)
Yellow Sputum
Yellow colored sputum is due to the presence of white blood cells, particularly neutrophils and
eosinphils. These cells are often present in chronic inflammation, allergic and infectious causes. With
infections, it is often in the acute setting that yellow sputum is evident due to the presence of live
neutrophils. With allergic conditions, particularly airway hypersensitivity, the yellowish sputum is due
to the presence of eosinophils.
Acute bronchitis white to yellow
Acute pneumonia white to yellow
Asthma white to yellow (thick)
Green Sputum
Green mucus is indicative of a long-standing, possibly chronic, infection. The color is a result of the
breakdown of neutrophils and the release of verdoperioxidase / myeloperioxidase, an enzyme that is
present within these cells. It may also be seen in long standing non-infectious inflammatory conditions.
With infections, the green sputum will be more purulent (large amounts of pus) while in noninfectious inflammatory conditions, the green sputum will be more mucoid (large amounts of mucus).