MATERIAL SAFETY DATA SHEET

Cat#K656-100 Isocitrate Assay Kit

MSDS DATE: 07/25/2011

SECTION 1: PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME:

Isocitrate Assay Kit

PRODUCT CODES:

Cat# K656-100

MANUFACTURER:
DIVISION:
ADDRESS:

BioVision, Inc.
980 Linda Vista Avenue, Mountain View, CA 94043

EMERGENCY PHONE: 858-373-8066

CHEMTREC PHONE:
OTHER CALLS:
650-428-0236
FAX PHONE:
650-428-0336

SECTION 2: COMPOSITION/INFORMATION ON INGREDIENTS

Component
Isocitrate Assay Buffer

Description
Proprietary Buffer with some NP-40 (< 0.5
%)

Volume

Safety Information

25 ml

See below

No hazardous or toxic
properties known
No hazardous or toxic
Substrate Mix
Lyophilized
1 vial
properties known
No hazardous or toxic
Isocitrate Standard
lyophilized
1 vial
properties known
NOTE: The safety data shown below is based on pure ingredients: The amount in this kit comprises much less.
Isocitrate Enzyme Mix

Proprietary mix

0.2 ml

SECTION 3: HAZARDS IDENTIFICATION

Component
NP-40

CAS Number
9036-19-5

MW
603 (FW)

Chemical Formula
(C2H4O)nC14H22O
N = 9-10

Safety Information
Potential Health Effects
Inhalation May be harmful if inhaled. Causes respiratory tract
irritation.
Skin May be harmful if absorbed through skin. Causes skin
irritation.
Eyes Causes eye irritation.
Ingestion May be harmful if swallowed.

SECTION 4: FIRST AID MEASURES_______________________________________________________________________________

General advice: Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

SECTION 5: FIRE-FIGHTING MEASURES

Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
SECTION 6: ACCIDENTAL RELEASE MEASURES

Personal precautions
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Keep in suitable, closed containers for disposal.

PAGE 1 OF 4

MATERIAL SAFETY DATA SHEET

Cat#K656-100 Isocitrate Assay Kit

MSDS DATE: 07/25/2011

SECTION 7: HANDLING AND STORAGE

NP-40:
Precautions for safe handling
Avoid inhalation of vapour or mist. Normal measures for preventive fire protection.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to
prevent leakage.
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION________________________________________________________
NP-40:
Components
Ethylene Oxide
Remarks

1,4-Dioxane
Remarks

Cas No.
Value
Control Parameters
Update
Basis
75-21-8
TWA
1 ppm
Jan 1, 2007
USA. ACGIH Threshold Limit Values (TLV)
Central Nervous System impairment Cancer Suspected human carcinogen: Human data are accepted as adequate in
quality but are conflicting or insufficient to classify the agent as a confirmed human carcinogen; OR, the agent is
carcinogenic in experimental animals at dose(s), by route(s) of exposure, at site(s), of histologic type(s), or by
mechanism(s) considered relevant to worker exposure. The A2 is used primatrily when there is limited evidence of
carcinogenicity in humans and sufficient evidence of carcinogenitity in experimental animals with relevance to humans.
TWA
1 ppm
Mar 1, 1989
USA. OSHA - TABLE Z-1 Limits for Air Contaminants 1910.1000
Sec 1910.1047 Ethylene Oxide
STEL
5 ppm
Mar 1, 1989
USA. OSHA - TABLE Z-1 Limits for Air Contaminants 1910.1000
Sec 1910.1047 Ethylene Oxide
TWA
1 ppm
Jun 30, 1993
USA. Occupational Exposure Limits (OSHA) - Table Z1 Limits for Air Contaminants
STEL
5 ppm
Jun 30, 1993
USA. Occupational Exposure Limits (OSHA) - Table Z1 Limits for Air Contaminants
Substance listed; for more information see OSHA document 1910.1047
123-91-1
TWA
20 ppm
Jan 1, 2007
USA. ACGIH Threshold Limit Values (TLV)
Liver damage Confirmed animal carcinogen with unknown relevance to humans: The agent is carcinogenic in
experimental animals at a relatively high dose, by route(s) of administration, at site(s), of histologic type(s), or by
mechanism(s) that may not be relevant to worker exposure. Available epidemiologic studies do not confirm an increased
risk of cancer in exposed humans. Available evidence does not suggest that the agent is lilkely to cause cancer in
humans except under uncommon or unlikely routes or levels of exposure. Danger of cutaneous absorption
TWA
25 ppm; 90 mg/m3
Jan 19, 1989
USA. OSHA - TABLE Z-1 Limits for Air Contaminants 1910.1000
Skin notation
TWA
Aug 4, 1997
USA. Occupational Exposure Limits (OSHA) - Table Z1 Limits for Air Contaminants
Skin designation: The value in mg/m3 is approximate

SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES (Isopropanol)____

Property
Appearance:
pH:
Water Solubility:
Specific Gravity (g/ml):
Boiling Point (C):
Melting Point (C):
Flash Point (C):
Ignition Temperature (C):

NP-40
Clear liquid, viscous
Not available
Soluble
1.060
Not available
Not available
Not available
Not available

SECTION 10: STABILITY AND REACTIVITY

Property
Chemical stability
Conditions to avoid:
Materials to avoid:
Hazardous decomposition
products:

NP-40
Stable under recommended
storage conditions
Not available
Strong oxidizing agents
Carbon oxides

PAGE 2 OF 4

MATERIAL SAFETY DATA SHEET

Cat#K656-100 Isocitrate Assay Kit

MSDS DATE: 07/25/2011

SECTION 11: TOXICOLOGICAL INFORMATION

NP-40
Acute toxicity: LD50 Oral - rat - 4,500 mg/kg
Skin corrosion/irritation: no data available
Serious eye damage/eye irritation: Eyes - rabbit - Severe eye irritation - Draize Test
Respiratory or skin sensitization: no data available
Germ cell mutagenicity: no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human
carcinogen by IARC.
ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by
ACGIH.
NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by
OSHA.
Reproductive toxicity: no data available
Specific target organ toxicity - single exposure (GHS): no data available
Specific target organ toxicity - repeated exposure (GHS): no data available
Aspiration hazard: no data available
12. ECOLOGICAL INFORMATION____________________________________________________________________________________
NP40
Toxicity: no data available
Persistence and degradability: no data available
Bioaccumulative potential: no data available
Mobility in soil: no data available
PBT and vPvB assessment: no data available
Other adverse effects: no data available
13. DISPOSAL____________________________________________________________________________________________________
NP40
Product: Observe all federal, state, and local environmental regulations. Offer surplus and non-recyclable solutions to a licensed
disposal company. Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging: Dispose of as unused product.
SECTION 14: TRANSPORT INFORMATION_________________________________________________________________________
NP40
DOT (US): Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods.
SECTION 15: REGULATORY INFORMATION_________________________________________________________________________
NP40
OSHA Hazards: Irritant
DSL Status: All components of this product are on the Canadian DSL list.
SARA 302 Components: Ethylene oxide CAS-No. 75-21-8 Revision Date 2007-07-01
SARA 313 Components: SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the
threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards Acute Health Hazard
CAS-No
Revision Date
Massachusetts Right To Know Components Ethylene oxide
75-21-8
2007-07-01
1,4-Dioxane
123-91-1
2007-07-01
Pennsylvania Right To Know Components -[(1,1,3,3-Tetramethylbutyl)phenyl]--hydroxy-poly(oxy-1,2-ethanediyl) CAS-No. 9036-19-5
Revision Date 1989-12-01
New Jersey Right To Know Components -[(1,1,3,3-Tetramethylbutyl)phenyl]--hydroxy-poly(oxy-1,2-ethanediyl) CAS-No. 9036-19-5
Revision Date 1989-12-01
California Prop. 65 Components
WARNING! This product contains a chemical known to the State of California to cause cancer.
CAS-No.
Revision Date
Ethylene oxide
75-21-8
1990-06-30
1,4-Dioxane
123-91-1
2007-09-28
California Prop. 65 Components
WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.Ethylene oxide
EU regulations
Component
NP-40

Risk Phrases
R37/41

Safety Phrases
S26/39

PAGE 3 OF 4

MATERIAL SAFETY DATA SHEET

Cat#K656-100 Isocitrate Assay Kit

MSDS DATE: 07/25/2011

SECTION 16: OTHER INFORMATION

OTHER INFORMATION:
PREPARATION INFORMATION:
DISCLAIMER:
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a
guide. The information in this document is based on the present state of our knowledge and is applicable to the
product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the
product. BioVision, Inc., shall not be held liable for any damage resulting from handling or from contact with the
above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.

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