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WHO Collaborating Centre for Research, Education & Training in Diabetes, M.V. Hospital for Diabetes &
Diabetes Research Centre, Chennai, India
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Results
Table I. Details of foot ulcers at baseline and presence of peripheral arterial disease among the study groups
Group 1
polyherbal formulation cream (n = 19)
N (%)
Group 2
silver sulphadiazine cream (n = 19)
N (%)
Plantar forefoot
12 (63.2)
13 (68.4)
5 (26.3)
4 (21.1)
2 (10.5)
2 (10.5)
Forefoot dorsum
5 (26.3)
6 (31.6)
II
5 (26.3)
7 (36.8)
III
9 (47.4)
6 (31.6)
Presence of osteomyelitis
3 (15.8)
4 (21.1)
5 (26.3)
4 (21.1)
14.9 13.6
14.0 8.4
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Group 1
Group 2
polyherbal
silver
formulation cream sulphadiazine cream
(n=19)
(n=19)
Mean age (yr)
59.4 8.6
58.7 4.6
HbA1c (%)
10.5 1.58
10.9 1.5
Duration of diabetes (yr)
13.7 6.5
12.1 4.4
Values are mean SD
Table III. Length and width of the wound at the baseline and
during follow up visits in each group
Wound
length x width
Polyherbal
formulation
cream
Group 1
(n = 19)
Silver
sulphadiazine
cream
Group 2
(n = 19)
4.98 1.5
4.3 1.4
Follow up
1st month
4.51 1.6
4.27 1.4
3rd month
3.99 1.51
3.7 1.5
5 month
3.39 1.8
2.8 2.0*
3.54 1.4
3.0 0.98
Follow up
1st month
3.2 1.3
2.95 0.95
3 month
2.75 1.3
2.37 0.97
5th month
2.38 1.4*
1.9 1.3*
43.1 26.8
43.6 30.7
9 (47.4)
8 (42.1)
th
rd
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2.
3.
4.
Lavery LA, Ashry HR, van Houtum W, Pugh JA, Harkless LB,
Basu S. Variation in the incidence and proportion of diabetesrelated amputations in minorities. Diabetes Care 1996; 19 :
48-52.
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6.
7.
8.
9.
10. Udupa SL, Shaila HP, Udupan AL, Ramesh KV, Kulkarni DR.
Wound healing properties of some medicinal plants. Biochem
Arch 1991; 7 : 207-12.
11. Dahanukar SA, Kulkarni RA, Rege NN. Pharmacology of
medicinal plants and natural products. Indian J Pharmacol
2000; 32 : S81-118.
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Reprint requests: Dr Vijay Viswanathan, Diabetes Research Centre (WHO Collaborating Centre for Research, Education & Training in
Diabetes), 5, Main Road, Royapuram, Chennai 600 013, India
e-mail: drvijay@mvdiabetes.com