Drug Name Dosage & Action Indication Adverse Effects Contraindication Nursing Responsibility

Route

Hypertension Angiotensin II
LOSARTAN receptor (type Hypertension CNS: Dizziness, Hypersensitivity to Assessment & Drug Effects
POTASSIUM Adult: PO 25– AT1) antagonist insomnia, headache. losartan, pregnancy
(lo-sar'tan) 50 mg in 1–2 acts as a potent GI: Diarrhea, [category C (first  Monitor BP at drug
divided doses vasoconstrictor dyspepsia. trimester), category trough (prior to a
Cozaar (max: 100 and primary Musculoskeletal: D (second and third scheduled dose).
mg/d); start vasoactive Muscle cramps, trimesters)], lactation  Monitor drug
Classifications: with 25 mg/d if hormone of the myalgia, back or leg effectiveness,
cardiovascular volume renin– pain. especially in African-
agent; angiotensin depleted (i.e., angiotensin– Respiratory: Nasal Americans when
ii receptor on diuretics) aldosterone congestion, cough, losartan is used as
antagonist; system. upper respiratory monotherapy.
antihypertensive infection, sinusitis.  Inadequate response
may be improved by
splitting the daily dose
into twice-daily dose.
 Lab tests: Monitor
CBC, electrolytes,
liver & kidney
function with long-
term therapy.

John Christian Macandog and Leslie Anne Maraňon From Nursingcrib.com