Drug Name Action Indication Contraindication Adverse Effect Drug Interaction Nursing Responsibilities

Generic Name Rebamipide is a Acute gastritis &

mucosal acute
Rebamipide protective agent exacerbation of Lactation. Rash, pruritus,
and is postulated chronic gastritis. constipation,
to increase gastric Gastric ulcer. diarrhea, nausea.
Brand Name: blood flow,
prostaglandin
Mucosta biosynthesis and
decrease free
oxygen radicals.
Drug
Classification:
Antacids,
Antireflux Agents Dosage:
& Antiulcerants Oral
Peptic ulcer,
Gastritis
Adult: 100 mg tid,
in the morning,
evening and
before bed.
Drug Name Action Indication Contraindication Adverse Effect Drug Interaction Nursing Responsibilities
Generic Name Symptomatic Alkalinization of
relief of Patients with Diarrhea or gastric content
Aluminum hyperacidity renal failure. constipation may decreases the
Magnesium associated w/ Partial intestinal occur to patients bioavailability of
Hydroxide peptic ulcer, obstruction, taking antacids Fe, ketoconazole
gastritis, appendicitis, fecal containing Mg & & tetracyclines.
esophagitis & impaction, gastric Al. The following The absorption of
Brand Name: Dosage: dyspepsia. outlet obstruction occur rarely: Due tetracyclines is
Adult 1-2 tab 1 hr Supplement to H2- & constipation. to Al(OH)3: further reduced
Kremil S after each meal blockers or proton Phosphate Proximal by its chelation
and at bedtime. pump inhibitors depletion, low myopathy; with Al & Mg ions.
for rapid relief of serum phosphate encephalopathy &
Drug ulcer symptoms. & osteomalacia. dementia may
Classification: Antiflatulent to occur in patient
Antacids, alleviate the w/ renal failure;
Antireflux Agents symptoms of intestinal
& Antiulcerants gassiness, obstruction; fecal
including post-op impaction;
gas pain, osteomalacia.
associated w/
hyperacidity.
Drug Name Action Indication Contraindication Adverse Effect Drug Interaction Nursing Responsibilities
Generic Name A semisynthetic Used in the . Before:
macrolide treatment of resp Hypersensitivity Diarrhea, nausea,
Clarithromycin antibiotic derived tract infections; to clarithromycin, abnormal taste, -Note sensitivity to
from skin & soft tissue erythromycin or dyspepsia, erythromycin or any macrolide
Brand Name: erythromycin that infections, any macrolides. abdominal antibiotics.
is active against a leprosy. pain/discomfort &
Baclecin variety of Prophylaxis & headache. -List drugs currently prescribed
microorganisms. It treatment of to prevent any interactions.
can inhibit protein oppurtunistic
Drug synthesis in myobacterial -Document onset, severity and
Classification: bacteria by infections. characteristics of S&S.
macrolide reversibly binding Alternative to
antibiotic to the 50S penicillins for
ribosomal prophylaxis of
subunits. This endocarditis. During:
inhibits the Eradication of H.
translocation of pylori in peptic -May administer with or
aminoacyl ulcer. without food.
transfer-RNA and
prevents peptide -Explain effects of the drug and
chain elongation. its side effects.

Dosage: -Administer as prescribed.

Mycobacterium
avium complex
500 mg bid for 7- After:
14 days. Leprosy,
-Report adverse effects or lack
H. pylori
eradication, of improvement after 48-72 hr.
severe infection
500 mg bid. -Report any persistent
diarrhea.

-Document administration of
medication.
Drug Name Action Indication Contraindication Adverse Effect Drug Interaction Nursing Responsibilities
Generic Name Domperidone is a For Reduces absorption
peripheral management Hypersensitivity. Drowsiness, of digoxin.
domperidone dopamine-receptor of dyspepsia, GI haemorrhage, extrapyramidal Increases
blocker. It increases heartburn, obstruction and reactions, absorption of
Brand Name: oesophageal epigastric pain, perforation, galactorrhoea, aspirin,
peristalsis, lower nausea, and patients with gynaecomastia; paracetamol and
Motilium oesophageal vomiting. prolactin releasing constipation or oral diazepam.
sphincter pressure, pituitary diarrhoea, lassitude, Enhances CNS
Drug gastric motility and hormone, chronic decreased libido, skin depression by
Classification: peristalsis, thus admin or routine rash, itch. phenothiazine.
GIT Regulators, facilitating gastric Dosage: prophylaxis of Potentially Fatal: Antimuscarinic
Antiflatulents & emptying and postoperative Convulsions, agents and opioids
Anti- decreasing small Nausea and nausea and arrhythmias and antagonise GI
inflammatories, bowel transit time. vomiting vomiting. cardiac arrest, effects. May
Antiemetics Onset: Oral: 30 min- Adult: 10-20 dysrrhythmias in antagonise
1hr. mg every 4-8 patients with CV hypoprolactinaemic
Duration: Oral: 6-8 hr. Max: 80 disease or effect of drugs such
hr. mg/day. hypokalaemia, as bromocriptine.
Absorption: Peak Child: >2 yr patients on cancer Increased effects
plasma and >35 kg: 10- chemotherapy. when used with
concentrations after 20 mg 3-4 Seizures; CYP3A4 inhibitors
1 hr (rectal), 30 min times daily. hypertensive crisis in such as
(oral). Max: 80 mg patients with erythromycin or
Distribution: Enters daily. phaeochromocytoma. ritonavir.
breast milk (small Oral
amounts). Protein- Non ulcer
binding: >90%. dyspepsia
Metabolism: Adult: 10-20
Extensively hepatic. mg tid and at
Excretion: Urine (as night.
metabolites), faeces -after meals
(as unchanged drug);
 7.5 hr (elimination
half-life).

Drug Name Action Indication Contraindication Adverse Effect Drug Interaction Nursing Responsibilities
Generic Name Hypersensitivity Before:
Semisynthe-tic or allergies to the
Amoxi-cillin broad-spectrum drug. GI: diarrhea, - Note reasons for therapy,
penicillin closely nausea, onset, and characteristics of
Brand Name: related to dyspepsia, S&S.
ampicillin. Binds vomiting,
Amoxil to penicillin- abdominal pain -Check for any allergic
binding proteins CNS: headache, reactions.
Drug (PBP-1 and PBP-3) Dosage: dizziness,
Classification: in the cytoplasmic confusion, -Note expiration date as
Anti-biotic, membranes of hallucination, expired products are
penicillin bacteria, thus 500mg per cap insomnia
nephrotoxic.
inhibiting cell wall
synthesis. Cell 2 caps PO 2x daily Allergic: urticaria,
division and mild skin
growth are eruption, During :
inhibited. anaphylactic
Destroyed by -Identify client
penicillinase, acid Miscella-neous:
stable and better hearing loss, rash, -Assess client in semi-fowler’s
absorbed than alteration in sense position and administer the
ampicillin. of smell, hepatic medication
failure
(Spratto, et al; . -Discontinue drug and notify
2008: 73) physician if a sensitivity
reaction occurs.
After:

-Document.

-Assess patient 30-60 minutes

after administration.

-Report unusual symptoms like

bruising, bleeding, sore throat,
and worsening of symptoms