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edition, 2008.
32. Biliary sludgePrevalence unknown in general population Predisposing
factors PregnancyRapid weight loss & prolonged fastingLong-term TPNCeftriaxone
Prolonged octreotide ttBone marrow transplantation Evolution (3 years) 50% resolve
spontaneously20% persist asymptomatically5 15 % develop gallstones10 15 %
become symptomatic Complications Biliary colic, AAC, pancreatitis
33. Biliary sludgeAlso known as biliary sandLow-amplitude nonshadowing
echoes in dependent portion of GBGore RM et al. Gastroenterol Clin N Am 2010 ;
39 : 265 287.Occasionally, sludge can be highly echogenic
34. PseudosludgeMcGahan J et al. Diagnostic ultrasound, Informa Healthcare,
2nd edition, 2008.Most commonly along posterior surface of gallbladderProduced by
sidelobe artifactsDisappear in different positions & when central portion of GB
scanned
35. Aggregated sludge Sludge ballMcGahan J et al. Diagnostic ultrasound,
Informa Healthcare, 2nd edition, 2008.Change in appearance or disappearance on
follow-upDifferentiates sludge ball from a stone or neoplasmNonshadowing mobile
echogenic structures
36. Aggregated sludge Tumefactive sludgeGB with tumor-like
sludgeRumack CM et al. Diagnostic Ultrasound. Elsevier-Mosby, St. Louis, USA, 3rd
edition, 2005.Potential mobility of sludgeNormal gallbladder wallNo vascularity
detected on Doppler USFollow-up
37. Biliary sludge"hepatization" of gallbladderRumack CM, Wilson SR, &
Charboneau JW. Diagnostic Ultrasound.Elsevier-Mosby, St. Louis, Missouri, USA,
3rd edition, 2005.GB entirely filled with sludge isoechoic to adjacent liverRecognized
by identifying normal GB wall
38. Blood in the gallbladderClinical history very useful for
diagnosisSonographic findings Echogenic or mixed echogenicity Fluid with lowlevel internal echoes Retractile May be mobileRumack CM et al. Diagnostic
Ultrasound. Elsevier-Mosby, St. Louis, USA, 3rd edition, 2005.Angled edges of
clotQuite typical of blood clots
39. Milk of calcium bile (limey bile)Diagnosis can be confirmed by abdominal
radiography or CTHigh-attenuation material withindependent portion of GBHighly
echogenic material independent portion of GB with ASRumack CM et al. Diagnostic
Ultrasound. Elsevier-Mosby, St. Louis, USA, 3rd edition, 2005.
40. Milk of calcium bile (limey bile)Abdominal radiography
41. Acute cholecystitis & its complications
42. Causes of right upper quadrant pain Peptic ulcer disease Pancreatitis
Hepatitis Appendicitis Hepatic congestion from right-sided heart failure
Perihepatitis (Fitz-Hugh-Curtis syndrome) Right lower lobe pneumonia Right-sided
pyelonephritis Nephro-ureterolithiasis
43. Diagnostic standard for acute cholecystitisTokyo guidelines 2007Hirota M
et al. J Hepatobiliary Pancreat Surg 2007 ; 14 : 78 82 .Three categories of diagnostic
findingsOne criterion from each category must be fulfilled(1) Murphy sign or
pain/tenderness in RUQ or RUQ mass(2) Fever, leukocytosis, or elevated CRP(3)
Confirmation by US or HIDA scan
44. Acute cholecystitis HIDA scanHigher accuracy than
ultrasonographyTalley NJ et al. Practical gastroenterology & hepatology: Liver &
biliary disease.Wiley Blackwell, Oxford, UK, First edition, 2010.Tracer in GBTracer
in CBDTracer in small bowelGBCBDSmallbowelNormal HIDA scanNon-filling of
GBTracer in CBDTracer in small bowelCBDSmallbowelAcute cholecystitis