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“ReaMetrix help us in keeping our commitment

in offering tests at affordable costs especially HIV.


We have so far conducted hundreds of tests and
have obtained accurate and reproducible results.
The availability of these reagents at this very af-
fordable price point has allowed us to significantly
reduce the cost of these tests to the patient.”

Dr. Sujay Prasad, Director, Anand Diagnostics

“With the new concept of dried reagents a sample


can be added to the reagent tube where the sample
is collected. The sample integrity is maintained
upto a week at temperatures upto 40°C. This gives
us tremendous flexibility in the way samples can
be handled.’

Dr.Anjali Kale, Head Reference Laboratory,


Dr Lal Pathlabs

ReaMetrix Accelerating Innovation

1585 Industrial Road


San Carlos, CA 94070
USA
Phone : +1 650 620 9253
Fax : +1 650 620 0093

50-B, II Phase
Peenya Industrial Area
Peenya, Bangalore 560058, India
Ph: +91-80-28378693/5
Fax: +91-80-41172451

E-mail: info@reametrix.com
Web: www.reametrix.com

ISO 9001:2008 www.reametrix.com


certified company
Company Process is our Product
ReaMetrix, Inc. is a next At ReaMetrix, we have built a
generation biotechnology world-class research and devel-
company that was founded with opment facility in Bangalore,
the unique business model of India with a primary focus of
using the “labor cost arbitrage” applying Six Sigma product de-
through India to create signifi- velopment strategies to diagnos-
cant and sustainable tic and life science products. We
“value arbitrage”. As with the believe that process control is a
early Silicon Valley entrepre- critical component of generating
neurs, we are working to build a high quality data and products.
company culture that provides Our corporate infrastructure
talented Indian scientists with is process-centric, and we live
an environment where they have by our philosophy on a daily
freedom to exercise their train- basis. Rigorous documentation,
ing, skills and imagination while full audit trails, and a dedicated
building corporate value. Our quality group result in high qual-
egalitarian approach allows us to ity products, and reproducible,
encourage and reward initiative trustworthy data. At ReaMetrix,
throughout our organization. Process is our Product.
Our people are the key to our
success. ReaMetrix is committed to
becoming the leading provider of
“The challenge of technological inno- high quality research and diag-
vation is to create solutions that are nostic assay solutions resulting
locally affordable and sustainable in in a transformation of the cost
the long run within the local macro- opportunities available in India
economic constraints. The solutions into value for both the biotech-
should permit generation of local nology and global health sectors.
economic activity that will reinforce
long-term economic sustainability.”

Bala S. Manian, CEO ReaMetrix


Inc.. Affordable Diagnostics—Chang-
ing the Paradigm in India. Cytometry
Part B (Clinical Cytometry) 74B
(Suppl. 1):S117–S122 (2008)
Reagents for
Diagnostic Use Decentralized Staining Concept
Blood samples from collection
Catalog Product/ Intended Format Storage Kit centres that operate in resource
Number Reagent Use Sizes poor settings, age by the time as
they are shipped to centralized
HIV Immunophenotyping testing facilities. CD receptors are
known to undergo a process called
25118-00 Dry Tri T-STAT For determining absolute counts of human Dry Room 50 “capping” (internalization of
total T, helper/inducer & suppressor/cytotoxic Temperature receptors), with sample ageing.
CD3/CD4/CD8 Reagent *
T lymphocytes in erythrocyte-lysed
whole blood Dry reagents enable staining to
be done in collection centres that
typically have no electricity to
run refrigeration units. Stained
25197-00 Dry Tri T-STAT For determining absolute lymphocyte count Dry Room 50
samples can then be transported
CD3/CD4/CD45 Reagent (ALC), percentages & absolute counts of hu- Temperature
without the need for cold chain.
man total T and helper/inducer T lymphocytes
in erythrocyte-lysed whole blood
The decentralized approach to
sample processing mitigates the
risk associated with variation in
25239-00 ReaPan 34845 For determining ALC, percentages and absolute Dry Room 50 cell counts. Studies on samples
Reagent counts of human total T, helper/inducer & Temperature stained and fixed using dry re-
Suppressor/cytotoxic T lymphocytes in eryth- agents have shown that there is no
rocyte-lysed whole blood drop in staining intensity or cell
count upto 8 days when stored at
room temperature.
25244-00 ReaPan 3 4 G Reagent For determining absolute counts of Dry Room 50
Reagent human total T, helper/inducer T lymphocytes Temperature
on Guava Platform
Regulatory Status
ReaMetrix Reagents conform to
highest international standards
25332-00 ReaPan 3 8 G For determining absolute counts of human Dry Room 50
total T, suppressor/cytotoxic T lymphocytes Temperature of quality. Most of the diagnostic
Reagent reagents are CE marked and/or
on Guava Platform
FDA cleared. For details, please
contact us.
25124-00 Rea T-Count CD4/ For determining absolute counts of human to- Dry Room 50
* For In Vitro Diagnostic Use
CD3 & CD8/CD3 tal T, helper/inducer & suppressor/cytotoxic T Temperature
lymphocytes in erythrocyte-fixed whole blood in the United States
(Dual tube) Reagent on BD FACSCount™ platform

25242-00 Rea T Count CD4/ For determining absolute counts of human Dry Room 50
CD3 (Single Tube) total T, helper/inducer T lymphocytes in Temperature
erythrocyte-fixed whole blood on
Reagent BD FACSCount™ platform
Reagents for
Diagnostic Use ReaPan S34: Ease in Workflow
ReaMetrix Stem cell enumera-
Catalog Product/ Intended Format Storage Kit tion reagents are provided in one
Number Reagent Use Sizes ready-to-use reagent dried tube.
The assay just needs addition
HLA B-27 Typing of sample, simplifying sample
preparation. Incubation time is 30
25238-00 ReaPan For detection of HLA-B27 antigen expression Dry Room 25 minutes, speeding time to results;
B27 in erythrocyte-lysed whole blood (LWB) using Temperature a boon to diagnostic labs that
flow cytometry process multiple samples simulta-
neously. Predispensed fluorescence
Hematopoietic CD34+ Stem Cell Enumeration reference beads included in the
reagent tube, ensure accurate
For enumeration of Hematopoietic stem cells enumeration of CD34+ cells
25323-00 ReaPan CD34+ in human peripheral or mobilized blood Dry Room 25 interest. The result: more efficient
S34 Temperature workflow and greater confidence
samples, umbilical cord blood samples, bone
marrow samples and leukapheresis samples by in results.
flow cytometry

Presence/Absence test for Bacteria in Urine ReaMetrix HLA B27 reagent:
Enabling Reduced HLA-B7 Cross
25329-00 ReaPan For screening of Urine samples for presence/ Dry Room 50 Reactivity
absence of bacteria by flow cytometry Temperature
Micro
The only existing flow

ReaCount Tubes cytometry based reagent featuring
two antibodies against the HLA-
25108-00 ReaCount Absolute Counting Fluorescent Beads-Provides Dry Room 50 B27 antigen. The result: increased
absolute counts for immunophenotyping Temperature Sensitivity. The reagent use anti-B7
Tubes
antibody against HLA-B7 antigen,
which ensures minimal cross reac-
tivity thus reducing the number of
false positives. The result: higher
Specificity. The reagent uses
built-in intensity controls in each
test making the assay highly ro-
bust and independent of external
standards.

Regulatory Status
ReaMetrix Reagents conform to
highest international standards
of quality. Most of the diagnostic
reagents are CE marked and/or
FDA cleared. For details, please
contact us.
Reagents for
Research Use

Catalog Product/ Typical Format Storage Kit


Number Reagent Usage Sizes

HIV Immunophenotyping
25347-00 Anti CD3-Atto488/CD4- For determining ALC, percentages and absolute Dry Room 50
PE-DyLight 594/CD8-PE/ counts of human total T, helper/inducer Temperature
& Suppressor/cytotoxic T lymphocytes in
CD45-PerCP Reagent erythrocyte-lysed whole blood on Beckman
Coulter 4 colour EPICS-XL Instrument

25384-00 Anti CD45-Atto 488 For determining ALC, percentages and absolute Dry Room 50
/ CD4-PE reagent counts of human helper/inducer T lympho- Temperature
cytes in erythrocyte-lysed whole blood

Human Platelets Enumeration

25348-00 Anti CD41-Atto488 & For determining absolute counts of human Dry Room 50
platelets in stained-fixed whole blood Temperature
CD61-Atto488 reagent
with Absolute
Counting Beads

Residual Leucocytes Enumeration

25387-00 7-Amino-actinomycin D For enumeration of residual leucocytes in Liquid 2-8 ° C 25


Leuco reduced blood products
( 7-AAD) nucleic acid dye

ready-to-use solution
with Absolute Counting
Beads

Human Reticulocyte Enumeration

25381-00 Anti CD235ab-Dy649/ For determining percentages and absolute Dry Room 50
counts of human reticulocytes and absolute Temperature
Thiazole Orange re-
count of erythrocytes using Flow Cytometry
agent with Absolute
Counting Beads
Reagents for
Research Use

Catalog Product/ Typical Format Storage Kit


Number Reagent Usage Sizes

Paroxysmal Nocturnal Haemoglobinuria (PNH) typing


CR70002-00 CD45-PerCP/ CD55-PE For Paroxysmal Nocturnal Haemo- Liquid 2-8 °C 25
globinuria Diagnosis by Granulocytes
CR70003-00 CD45-PerCP/ CD59-Atto488 and/or Erythrocyte Analysis using
Flow Cytometry
CR70004-00 CD45-PerCP/ MIgG1,k-PE

CR70005-00 CD45-PerCP/ MIgG2a,k-Atto488

Human Monocytes Enumeration

25341-00 Anti CD45-Atto488/CD14- For determining absolute counts & percent- Liquid 2-8 ° C 25
PE reagent with Absolute ages of human monocytes in erythrocyte-lysed
whole blood
Counting Beads

Sepsis Panel

CR70001-00 Anti CD11b-Atto488/ For measurement of neutrophil CD64 expres- Liquid 2-8 ° C 25
CD64-PE/CD15-PE-Dy649 sion on human blood leukocytes which cor-
relates with the presence of infection or sepsis
reagent with Absolute in humans
Counting Beads
Reagents for Research Use Using its own unique dried down reagent technology, ReaMetrix can
CUSTOM CONJUGATION SERVICES mix and match antibodies and fluorophores to create specific multicol-
ReaMetrix Multicolor Immunophenotyping Reagents or dried down L-L panels of reagents as per customer’s requirements.
(Leukemia-Lymphoma Panel)

PE-DyLight 594 PE-HiLyte 750 APC-HiLyte 750


(PE-Texas Red
Atto-488 Phycoerythrin PE-Dyomics 649 PerCP APC (PE-Cy7 equivalent) (APC-Cy7 equivalent)
Antibodies equivalent)
(FITC Equivalent) (PE) (PE-Cy5 equivalent)

CD2 25802-01 25802-02 25802-08 25802-03 25802-04 25802-05 25802-06 25802-07


CD3 25803-01 25803-02 25803-08 25803-03 25803-04 25803-05 25803-06 25803-07
CD4 25804-01 25804-02 25804-08 25804-03 25804-04 25804-05 25804-06 25804-07
CD5 25805-01 25805-02 25805-08 25805-03 25805-04 25805-05 25805-06 25805-07
CD7 25807-01 25807-02 25807-08 25807-03 25807-04 25807-05 25807-06 25807-07
CD8 25808-01 25808-02 25808-08 25808-03 25808-04 25808-05 25808-06 25808-07
CD10 25810-01 25810-02 25810-08 25810-03 25810-04 25810-05 25810-06 25810-07
CD11b 25811-01 25811-02 25811-08 25811-03 25811-04 25811-05 25811-06 25811-07
CD13 25813-01 25813-02 25813-08 25813-03 25813-04 25813-05 25813-06 25813-07
CD14 25814-01 25814-02 25814-08 25814-03 25814-04 25814-05 25814-06 25814-07
CD15 25815-01 25815-02 25815-08 25815-03 25815-04 25815-05 25815-06 25815-07
CD16 25816-01 25816-02 25816-08 25816-03 25816-04 25816-05 25816-06 25816-07
CD19 25819-01 25819-02 25819-08 25819-03 25819-04 25819-05 25819-06 25819-07
CD20 25820-01 25820-02 25820-08 25820-03 25820-04 25820-05 25820-06 25820-07
CD22 25822-01 25822-02 25822-08 25822-03 25822-04 25822-05 25822-06 25822-07
CD23 25823-01 25823-02 25823-08 25823-03 25823-04 25823-05 25823-06 25823-07
CD25 25825-01 25825-02 25825-08 25825-03 25825-04 25825-05 25825-06 25825-07
CD33 25833-01 25833-02 25833-08 25833-03 25833-04 25833-05 25833-06 25833-07
CD34 25834-01 25834-02 25834-08 25834-03 25834-04 25834-05 25834-06 25834-07
CD36 25835-01 25835-02 25835-08 25835-03 25835-04 25835-05 25835-06 25835-07
CD38 25838-01 25838-02 25838-08 25838-03 25838-04 25838-05 25838-06 25838-07
CD41 25841-01 25841-02 25841-08 25841-03 25841-04 25841-05 25841-06 25841-07
CD45 25845-01 25845-02 25845-08 25845-03 25845-04 25845-05 25845-06 25845-07

488 488 , 532 488 , 532 488 , 532 488 595, 633, 488, 532, 561 595, 633,
523 578 618 678 635, 647 785 635, 647
676
660 660

Emission Excitation Pack Minimum pack size depends on


Maximum (nm) Laser (nm) Sizes
Antibody-dye combination chosen
Reagents for Research Use This concept is suited to diagnostic labs that process multiple samples
CUSTOM CONJUGATION SERVICES simultaneously. This approach can be used to standardize panels (anti-
ReaMetrix Multicolor Immunophenotyping Reagents bodies and fluorophores) across various laboratories so that there can
(Leukemia-Lymphoma Panel) be an unbiased discussion of the results of immunophenotyping.

PE-DyLight 594 PE-HiLyte 750 APC-HiLyte 750


(PE-Texas Red
Atto-488 Phycoerythrin PE-Dyomics 649 PerCP APC (PE-Cy7 equivalent) (APC-Cy7 equivalent)
Antibodies equivalent)
(FITC Equivalent) (PE) (PE-Cy5 equivalent)

CD55 25855-01 25855-02 25855-08 25855-03 25855-04 25855-05 25855-06 25855-07


CD56 25856-01 25856-02 25856-08 25856-03 25856-04 25856-05 25856-06 25856-07
CD59 25859-01 25859-02 25859-08 25859-03 25859-04 25859-05 25859-06 25859-07
CD61 25861-01 25861-02 25861-08 25861-03 25861-04 25861-05 25861-06 25861-07
CD64 25864-01 25864-02 25864-08 25864-03 25864-04 25864-05 25864-06 25864-07
CD73 25873-01 25873-02 25873-08 25873-03 25873-04 25873-05 25873-06 25873-07
CD79a 25879-01 25879-02 25879-08 25879-03 25879-04 25879-05 25879-06 25879-07
CD90 25890-01 25890-02 25890-08 25890-03 25890-04 25890-05 25890-06 25890-07
CD103 25903-01 25903-02 25903-08 25903-03 25903-04 25903-05 25903-06 25903-07
CD105 25905-01 25905-02 25905-08 25905-03 25905-04 25905-05 25905-06 25905-07
CD117 25917-01 25917-02 25917-08 25917-03 25917-04 25917-05 25917-06 25917-07
HLA-DR 25750-01 25750-02 25750-08 25750-03 25750-04 25750-05 25750-06 25750-07
Kappa 25751-01 25751-02 25751-08 25751-03 25751-04 25751-05 25751-06 25751-07
Lambda 25752-01 25752-02 25752-08 25752-03 25752-04 25752-05 25752-06 25752-07
IgM 25753-01 25753-02 25753-08 25753-03 25753-04 25753-05 25753-06 25753-07
TCR αβ 25754-01 25754-02 25754-08 25754-03 25754-04 25754-05 25754-06 25754-07
TCR γδ 25755-01 25755-02 25755-08 25755-03 25755-04 25755-05 25755-06 25755-07
MPO 25756-01 25756-02 25756-08 25756-03 25756-04 25756-05 25756-06 25756-07
FMC7 25757-01 25757-02 25757-08 25757-03 25757-04 25757-05 25757-06 25757-07
Mouse IgG1, κ 25758-01 25758-02 25758-08 25758-03 25758-04 25758-05 25758-06 25758-07
Mouse IgG2a, κ 25759-01 25759-02 25759-08 25759-03 25759-04 25759-05 25759-06 25759-07
Mouse IgG2b, κ 25760-01 25760-02 25760-08 25760-03 25760-04 25760-05 25760-06 25760-07
Mouse IgG3 25761-01 25761-02 25761-08 25761-03 25761-04 25761-05 25761-06 25761-07

488 488 , 532 488 , 532 488 , 532 488 595, 633, 488, 532, 561 595, 633,
523 578 618 678 635, 647 785 635, 647
676
660 660

Emission Excitation Pack Minimum pack size depends on


Maximum (nm) Laser (nm) Sizes Antibody-dye combination chosen
Reagent
Accessories

Catalog Product/ Typical Format Storage Kit


Number Reagent Usage Sizes

Accessories for Diagnostic Use

25237-00 ReaLyse lysing Solution Erythrolytic reagent intended for lysing red Liquid Room 50
blood cells to enable a lyse-no wash protocol Temperature ml
(10X Concentrate)

25325-00 ReaFix Fixative Solution Fixative solution intended for the fixation of Liquid Room 50
cell preparations Temperature ml
(5% Formaldehyde)

25326-00 ReaFix Diluent solution used for dilution of Fixative Liquid Room 50
solution Temperature ml
(Diluent Solution)

25386-00 ReaFlow Buffered sheath fluid meant for use on most Liquid Room 4 cans
flow cytometer systems. Temperature (each 5 l)
Other
Services

Design of Research Reagents Custom Cell Line Development Services

Bead Based FLISA Assay ReaMetrix offers development


of stable cell lines expressing
Bead Based FLISA for Quantita-
protein of interest at high,
tive Estimation of Antigen Con-
homogenous levels
centrations by Flow Cytometry
technique

We provide a complete
Detection of PCR Products on development solution from, the
Flow Cytometry Assay cloning of novel genes into suitable
expression vectors, transfection
Qualitative Detection of PCR optimization, stable clone isolation
Products on Flow Cytometry

Custom Conjugation Services

ReaMetrix offers custom


conjugation services in
Antibody, proteins,
Chemokines, micro and
nanosphere conjugations with
fluorophores and
Quantum dots

ReaMetrix can customize Antibody-


Dye combinations to meet your
requirements