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CANLAS, Laurence Bernard Jasper E.

27,2016
MWF 1:00-3:00 0926L

January

Score:
Group 3

MICROBIAL CONTROL

Chemical

Phenols

Action
Phenols and its
derivaatives act by
denaturing proteins,
especially in the cell
membrane.1
Denatures proteins
Coagulates proteins2

Bisphenols

Denatures proteins
Coagulates porteins

Biguanides

Destroys bacterial cells


by disrupting cell
membranes and possibly
cell walls by blocking
the synthesis of lipids.5

Uses
germicide
used in mouthwashes,
topical antiseptics and
throat lozenges.3

Comments
phenol is expensive,
pungent oder and caustic
to the skin.
4

used in Lysol and


Amphyl.
(Orthophenyphenol)
used in toothpaste,
underarm deodorant,
and bath soaps.
(Hexachlorophene)
used in surgical scrub,
handwash and
superficial wound
cleanser.

combination of 2 phenol
molecules

Relative to phenol

Halogens

Protein oxidation and


Water treatment, skin
membrane leakage. (Cl) antisepsis, equipment
Reacts with proteins. (I) spraying, food
processing and
preoperative
preparation.

Inactivated by organic
matter.
objectionable taste and
odor.

Alcohol

Denatures proteins
Dissolves lipids
Dehydrating agent

Instrument disinfectant
and skin antiseptic

Precleaning necessary
skin irritation

Combines with -SH


group in proteins. (Hg)
Combines with proteins.
(Cu)

Skin antiseptics and


disinfectant. (Hg)
Algicide is swimming
pools and municipal

Inactivated by organic
matter.
Toxic to tissues
Slow acting

Heavy Metals

1Pommerville, Jeffrey C. (2011); Alcamo's Fundamentals of Microbiology 9th Edition; Jones and Bartlett Publishers; p.210
2Pommerville, Jeffrey C. (2011); Alcamo's Fundamentals of Microbiology 9th Edition; Jones and Bartlett Publishers; p.216
3Pommerville, Jeffrey C. (2011); Alcamo's Fundamentals of Microbiology 9th Edition; Jones and Bartlett Publishers; p.210
4Pommerville, Jeffrey C. (2011); Alcamo's Fundamentals of Microbiology 9th Edition; Jones and Bartlett Publishers; p.210
5Pommerville, Jeffrey C. (2011); Alcamo's Fundamentals of Microbiology 9th Edition; Jones and Bartlett Publishers; p.211

Binds proteins.(Ag)

Surface Active Agents

Chemical Food
Preservative

Dissolve lipids in cell


membranes

water supplies. (Cu)


Skin antiseptic. Eyes of
Newborns (Ag)
Industrial sanitation
skin antiseptic
disinfectant

Wound treatment
Acne
Embalming
Creats aerobic
Vaccine production
environment
Gaseous sterilant
Oxidizes protein groups Sterilization of
Reacts with functional instruments,
groups in proteins and
equipments,heat
nucleic acids
sensitive objects and
surgical supplies.
Sanitizes equipment,
rooms and buildings.

skin irritation
Neutralized by soap.

Limited use
Poor penetration
Allergenic
Toxic to tissues
Neutralized by organic
matter
Unstable
Toxic to skin
Explosive
Requires constant
humidity
Burns skin and eyes
upon contact

6 All until Chemical food preservatives that dont have references: Pommerville, Jeffrey C. (2011); Alcamo's
Fundamentals of Microbiology 9th Edition; Jones and Bartlett Publishers; p.216

CANLAS, Laurence Bernard Jasper E.


27,2016
MWF 1:00-3:00 0926L

January

MICROBIAL CONTROL

Autoclave

Score:

Hot Air Sterilizer

Dessicator