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It can
be also used to treat some protozoal diseases like malaria and can be useful against some
methicillin-resistant Staphylococcus aureus infections. Clindamycin is also common topical
treatment for acne. Common brand names are Anerocin, Clindal, Dalacin, Dalacin C, Inprosyn-
HP, Klindex, and Zindal. Clindamycin is classified as Lincosamide and Antibiotic.
Indication of Clindamycin
Treatment of respiratory tract, skin or soft tissue, chronic bone or joint infections; septicemia;
intra-abdominal, female genitourinal infections; bacterial vaginosis; endocarditis. Can be used for
acne vulgaris. Clindamycin is used for treatment of malaria, otitis media, Pneumocystis carinii
pneumonia, and toxoplasmosis.
Route and Dosage of Clindamycin
IV/IM: ADULTS, ELDERLY: 1.2-1.8 g/day in 2-4 divided doses. CHILDREN: 25-40 mg/kg/day in
3-4 divided doses. Maximum: 4.8 g/day.
PO: ADULTS, ELDERLY: 150-450 mg/dose q6-8h. CHILDREN: 10-30 mg/kg/day in 3-4 divided
doses. Maximum: 1.8 g/day.
Bacterial Vaginosis
Intravaginal: ADULTS: One applicatorful at bedtime for 3-7 days or 1 suppository at bedtime for 3
days.
* Abdominal pain
* Nausea and Vomiting
* Diarrhea
* Vaginitis and itching
* Dry scaly skin
* Phlebitis, thrombophlebitis with IV administration
* Pain, induration, at the IM injection site
* Allergic reaction, urticaria, pruritus
* Headache and dizziness
* Contact dermatitis
* Hypersensitivity reaction
* Antibiotic-associated colitis (Severe abdominal pain, tenderness, fever, watery and severe
diarrhea)
* Blood dyscrasias (Leukopenia and thrombocytopenia)
* Nephrotoxicity (Proteinuria, azotemia, oliguria)