UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

OFFICE OF
PREVENTION, PESTICIDES AND
TOXIC SUBSTANCES

Inert Ingredients Eligible for FIFRA 25(b) Pesticide Products

Last Updated December 20, 2010

Provided below are the inert ingredients that are eligible for inclusion in pesticide products
under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)s Section 25(b).
This listing of minimal risk inert ingredients updates what has been historically referred to
as 4A under Pesticide Registration Notice 2000-6.
1. Commonly consumed food commodities, animal feed items, and edible fats and oils as described
in 40 CFR 180.950(a), (b), and (c) may be used as inert ingredients in FIFRA Section 25(b) pesticide
products applied to food use sites (e.g., food crops, animals used for food) and in FIFRA Section
25(b) pesticide products applied to nonfood use sites (e.g., ornamental plants, highway right-ofways, rodent control). Specific chemical substances listed under 40 CFR 180.950(e) that are also
acceptable for use as inert ingredients in FIFRA Section 25(b) pesticide products are included in the
table below.
2. In addition to (1) above, the following inert ingredients are also eligible for inclusion in FIFRA
Section 25(b) pesticide products. These ingredients are listed by CAS Registry Number and
chemical name (common names are given, with systematic names included as synonyms in brackets
where applicable). In addition, this listing has two columns to indicate whether the inert ingredient
can be used in FIFRA Section 25(b) products applied to food use and/or nonfood use sites.

CAS Reg. No.

77-90-7
9002-18-0
N/A
N/A
10016-20-3
1327-36-2
1327-43-1
12736-96-8

Chemical Name
Acetyl tributyl citrate
[Citric acid, 2-(acetyloxy)-, tributyl ester]
Agar
Almond hulls
Almond shells
alpha-Cyclodextrin
Aluminatesilicate
Aluminum magnesium silicate
[Silicic acid, aluminum magnesium salt]
Aluminum potassium sodium silicate
[Silicic acid, aluminum potassium sodium salt]
1

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CAS Reg. No.

1335-30-4
1344-00-9
12003-51-9
1863-63-4
1002-89-7
113894-85-2
125109-81-1
N/A
137-66-6
12174-11-7
8012-89-3
1302-78-9
85049-30-5
7585-39-9
68409-75-6
N/A
N/A
34451-19-9
138-22-7
123-95-5
N/A
13397-26-7
62-54-4
5743-26-0
2090-05-3
471-34-1
7693-13-2
6107-56-8
12168-85-3
1344-95-2
1592-23-0

Chemical Name
Aluminum silicate
Aluminum sodium silicate
[Silicic acid, aluminum sodium salt]
Aluminum sodium silicate (1:1:1)
[Silicic acid (H4SiO4), aluminum sodium salt (1:1:1)]
Ammonium benzoate
[Benzoic acid, ammonium salt]
Ammonium stearate
[Octadecanoic acid, ammonium salt]
Amylopectin, acid-hydrolyzed, 1-octenylbutanedioate
Amylopectin, hydrogen 1-octadecenylbutanedioate
Animal glue
Ascorbyl palmitate
Attapulgite-type clay
Beeswax
Bentonite
Bentonite, sodian
beta-Cyclodextrin
Bone meal
Bran
Bread crumbs
(+)-Butyl lactate
[Lactic acid, n-butyl ester, (S)]
Butyl lactate
[Lactic acid, n-butyl ester]
Butyl stearate
[Octadecanoic acid, butyl ester]
Calcareous shale
Calcite (Ca(Co3))
Calcium acetate
Calcium acetate monohydrate
[Acetic acid, calcium salt, monohydrate]
Calcium benzoate
[Benzoic acid, calcium salt]
Calcium carbonate
Calcium citrate
[Citric acid, calcium salt]
Calcium octanoate
Calcium oxide silicate (Ca3O(SiO4))
Calcium silicate
[Silicic acid, calcium salt]
Calcium stearate
[Octadecanoic acid, calcium salt]
2

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CAS Reg. No.

7778-18-9
10101-41-4
10034-76-1
N/A
7440-44-0
124-38-9
9000-11-7
N/A
8015-86-9
9000-40-2
9000-07-1
9000-71-9
8001-79-4
8001-78-3
N/A
9004-34-6
9004-35-7
51395-75-6
65996-61-4
68442-85-3
N/A
479-61-8
519-62-0
N/A
77-92-9
5949-29-1
9000-69-5
68514-76-1
N/A
8002-31-1
N/A
N/A
8001-69-2
68916-18-7
N/A
61789-98-8
N/A
N/A
68424-10-2
N/A

Chemical Name
Calcium sulfate
Calcium sulfate dihydrate
Calcium sulfate hemihydrate
Canary seed
Carbon
Carbon dioxide
Carboxymethyl cellulose
[Cellulose, carboxymethyl ether]
Cardboard
Carnauba wax
Carob gum
[Locust bean gum]
Carrageenan
Caseins
Castor oil
Castor oil, hydrogenated
Cat food
Cellulose
Cellulose acetate
Cellulose, mixture with cellulose carboxymethyl ether,
sodium salt
Cellulose, pulp
Cellulose, regenerated
Cheese
Chlorophyll a
Chlorophyll b
Citrus meal
Citric acid
Citric acid, monohydrate
Citrus pectin
Citrus pulp
Clam shells
Cocoa
Cocoa shell flour
Cocoa shells
Cod-liver oil
Coffee grounds
Cookies
Cork
Corn cobs
Cotton
Cottonseed meal
Cracked wheat
3

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Nonfood
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CAS Reg. No.

26402-22-2
9004-53-9
49553-76-6
12694-22-3
27638-00-2
26657-95-4
3609-96-9
144-33-2
7727-73-3
61790-53-2
27215-38-9
16389-88-1
N/A
N/A
N/A
687-47-8
97-64-3
68476-25-5
N/A
8016-13-5
8031-18-3
110-17-8
17465-86-0
9000-70-8
71010-52-1
68476-37-9
56-81-5
111-03-5
36354-80-0
53563-63-6

Chemical Name
Decanoic acid, monoester with 1,2,3-propanetriol
Dextrins
Diglyceryl monooleate
[9-Octadecenoic acid, ester with 1,2,3-propanetriol]
Diglyceryl monostearate
[9-Octadecanoic acid, monoester with oxybis(propanediol)]
Dilaurin
[Dodecanoic acid, diester with 1,2,3-propanetriol]
Dipalmitin
[Hexadecanoic acid, diester with 1,2,3-propanetriol]
Dipotassium citrate
[Citric acid, dipotassium salt]
Disodium citrate
[Citric acid, disodium salt]
Disodium sulfate decahydrate
Diatomaceous earth (less than 1% crystalline silica)
[Kieselguhr; Diatomite]
Dodecanoic acid, monoester with 1,2,3-propanetriol
Dolomite
Douglas fir bark
Egg shells
Eggs
(+)-Ethyl lactate
[Lactic acid, ethyl ester, (S)]
Ethyl lactate
[Lactic acid, ethyl ester]
Feldspar
Fish meal
Fish oil (not conforming to 40 CFR 180.950)
Fuller's earth
Fumaric acid
gamma-Cyclodextrin
Gelatins
Gellan gum
Glue (as depolymd. animal collagen)
Glycerin
[1,2,3-Propanetriol]
Glycerol monooleate
[9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester]
Glyceryl dicaprylate
[Octanoic acid, diester with 1,2,3-propanetriol]
Glyceryl dimyristate
[Tetradecanoic acid, diester with 1,2,3-propanetriol]
4

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Nonfood
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CAS Reg. No.

25637-84-7
1323-83-7
27214-38-6
26402-26-6
25496-72-4

31566-31-1
11099-07-3
N/A
7782-42-5
9000-30-0
9000-01-5
9000-65-1
13397-24-5
1317-60-8
1415-93-6
68334-00-9
84681-71-0
8016-70-4
9004-62-0
9004-64-2
9004-65-3
12068-86-9
1309-37-1
12259-21-1
1317-61-9
1345-25-1
67-63-0
110-27-0
1332-58-7
63-42-3
64044-51-5
8006-54-0

Chemical Name
Glyceryl dioleate
[9-Octadecenoic acid (9Z)-, diester with 1,2,3-propanetriol]
Glyceryl distearate
Glyceryl monomyristate
[Tetradecanoic acid, monoester with 1,2,3-propanetriol]
Glyceryl monooctanoate
[Octanoic acid, monoester with 1,2,3-propanetriol]
Glyceryl monooleate
[9-Octadecenoic acid (9Z)-, monoester with 1,2,3propanetriol]
Glyceryl monostearate
[Octadecanoic acid, monoester with 1,2,3-propanetriol]
Glyceryl stearate
[Octadecanoic acid, ester with 1,2,3-propanetriol]
Granite
Graphite
Guar gum
Gum arabic
Gum tragacanth
Gypsum
Hematite (Fe2O3)
Humic acid
Hydrogenated cottonseed oil
Hydrogenated rapeseed oil
Hydrogenated soybean oil
Hydroxyethyl cellulose
[Cellulose, 2-hydroxyethyl ether]
Hydroxypropyl cellulose
[Cellulose, 2-hydroxypropyl ether]
Hydroxypropyl methyl cellulose
[Cellulose, 2-hydroxypropyl methyl ether]
Iron magnesium oxide (Fe2MgO4)
Iron oxide (Fe2O3)
Iron oxide (Fe2O3), hydrate
Iron oxide (Fe3O4)
Iron oxide (FeO)
Isopropyl alcohol
[2-Propanol]
Isopropyl myristate
Kaolin
Lactose
Lactose monohydrate
Lanolin
5

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Nonfood
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CAS Reg. No.

N/A
143-07-7
8002-43-5
68916-91-6
12001-27-3
1317-65-3
8001-26-1
546-93-0
553-70-8
1309-48-4
12207-97-5
1343-88-0
1343-90-4
14987-04-3
557-04-0
7487-88-9
10034-99-8
6915-15-7
8002-48-0
N/A
9050-36-6
9004-67-5
12003-38-2
12001-26-2
8049-98-7
N/A
8012-95-1
142-18-7
589-68-4
53998-07-1
26657-96-5
866-83-1
18996-35-5
1318-93-0

Chemical Name
Latex rubber
Lauric acid
Lecithins
Licorice extract
Lime (chemical) dolomitic
Limestone
Linseed oil
Magnesium carbonate
[Carbonic acid, magnesium salt (1:1)]
Magnesium benzoate
Magnesium oxide
Magnesium oxide silicate (Mg3O(Si2O5)2), monohydrate
Magnesium silicate
Magnesium silicate hydrate
Magnesium silicon oxide (Mg2Si3O8)
Magnesium stearate
[Octadecanoic acid, magnesium salt]
Magnesium sulfate
Magnesium sulfate heptahydrate
Malic acid
Malt extract
Malt flavor
Maltodextrin
Methylcellulose
[Cellulose, methyl ether]
Mica
Mica-group minerals
Milk
Millet seed
Mineral oil (U.S.P.)
1-Monolaurin
[Dodecanoic acid, 2,3-dihydroxypropyl ester]
1-Monomyristin
[Tetradecanoic acid, 2,3-dihydroxypropyl ester]
Monomyristin
[Decanoic acid, diester with 1,2,3-propanetriol]
Monopalmitin
[Hexadecanoic acid, monoester with 1,2,3-propanetriol]
Monopotassium citrate
[Citric acid, monopotassium salt
Monosodium citrate
[Citric acid, monosodium salt
Montmorillonite
6

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Nonfood
Use

CAS Reg. No.

544-63-8
37244-96-5
7727-37-9
N/A
N/A
764-71-6
1984-06-1
8007-69-0
68917-73-7
112-80-1
N/A
8002-75-3
68514-74-9
57-10-3
N/A
8002-74-2
N/A
N/A
N/A
N/A
9000-69-5
130885-09-5
93763-70-3
26499-65-0
9002-88-4
9007-48-1
9009-32-9
127-08-2
1327-44-2
582-25-2
298-14-6
7447-40-7
7778-49-6
68514-28-3
13429-27-1
143-18-0

Chemical Name
Myristic acid
Nepheline syenite
Nitrogen
Nutria meat
Nylon
Octanoic acid, potassium salt
Octanoic acid, sodium salt
Oils, almond
Oils, wheat
Oleic acid
Oyster shells
Palm oil
Palm oil, hydrogenated
Palmitic acid
[Hexadecanoic acid]
Paper
Paraffin wax
Peanut butter
Peanut shells
Peanuts
Peat moss
Pectin
Perlite
Perlite, expanded
Plaster of paris
Polyethylene
Polyglyceryl oleate
Polyglyceryl stearate
Potassium acetate
[Acetic acid, potassium salt]
Potassium aluminum silicate, anhydrous
Potassium benzoate
[Benzoic acid, potassium salt]
Potassium bicarbonate
[Carbonic acid, monopotassium salt]
Potassium chloride
Potassium citrate
[Citric acid, potassium salt]
Potassium humate
[Humic acids, potassium salts]
Potassium myristate
[Tetradecanoic acid, potassium salt]
Potassium oleate
7

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Nonfood
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CAS Reg. No.

7492-30-0

24634-61-5
593-29-3
7778-80-5
7646-93-7
108-32-7
1332-09-8
N/A
N/A
N/A
9006-04-6
N/A
N/A
112945-52-5
7699-41-4
7631-86-9
63231-67-4
112926-00-8
10279-57-9
60676-86-0
13776-74-4
N/A

1393-03-9
308076-02-0
127-09-3
9005-38-3
532-32-1
144-55-8
9004-32-4

Food
Chemical Name
Use1/
[9-Octadecenoic acid (9Z)-, potassium salt]
Potassium ricinoleate
[9-Octadecenoic acid, 12-hydroxy-, monopotassium salt, (9Z,
12R)-]
Potassium sorbate
[Sorbic acid, potassium salt ]
Potassium stearate
[Octadecanoic acid, potassium salt]
Potassium sulfate
Potassium sulfate
[Sulfuric acid, monopotassium salt]
1,2-Propylene carbonate
[1,3-Dioxolan-2-one, 4-methyl-]
Pumice
Red cabbage color (expressed from edible red cabbage heads
via a pressing process using only acidified water)
Red cedar chips
Red dog flour
Rubber
Sawdust
Shale
Silica, amorphous, fumed (crystalline free)
Silica, amorphous, precipated and gel
Silica (crystalline free)
Silica gel
Silica gel, precipitated, crystalline-free
Silica, hydrate
Silica, vitreous
Silicic acid (H2SiO3), magnesium salt (1:1)
Soap (The water soluble sodium or potassium salts of fatty
acids produced by either the saponification of fats and oils, or
the neutralization of fatty acid)
Soapbark
{Quillaja saponin]
Soapstone
Sodium acetate
[Acetic acid, sodium salt]
Sodium alginate
Sodium benzoate
[Benzoic acid, sodium salt]
Sodium bicarbonate
Sodium carboxymethyl cellulose
[Cellulose, carboxymethyl ether, sodium salt]
8

Nonfood
Use

CAS Reg. No.

7647-14-5
994-36-5
68131-04-4
143-19-1
5323-95-5

822-16-2
7757-82-6
50-70-4
N/A
8030-76-0
N/A
68308-36-1
68513-95-1
57-11-4
7704-34-9
68425-17-2
71012-10-7
813-94-5
77-93-0
866-84-2
6100-05-6
68-04-2
6132-04-3
6858-44-2
57455-37-5
57-13-6
121-33-5

Chemical Name
Sodium chloride
Sodium citrate
Sodium humate
[Humic acids, sodium salts]
Sodium oleate
Sodium ricinoleate
[9-Octadecenoic acid, 12-hydroxy-, monosodium salt,
(9Z,12R)-]
Sodium stearate
[Octadecanoic acid, sodium salt]
Sodium sulfate
Sorbitol
[D-glucitol]
Soy protein
Soya lecithins
[Lecithins, soya]
Soybean hulls
Soybean meal
Soybean, flour
Stearic acid
[Octadecanoic acid]
Sulfur
Syrups, hydrolyzed starch, hydrogenated
Tetragylceryl monooleate
[9-Octadecenoic acid (9Z)-, monoester with tetraglycerol]
Tricalcium citrate
[Citric acid, calcium salt (2:3)]
Triethyl citrate
[Citric acid, triethyl ester
Tripotassium citrate
[Citric acid, tripotassium salt]
Tripotassium citrate monohydrate
[Citric acid, tripotassium salt, monohydrate]
Trisodium citrate
[Citric acid, trisodium salt]
Trisodium citrate dehydrate
[Citric acid, trisodium salt, dehydrate]
Trisodium citrate pentahydrate
[Citric acid, trisodium salt, pentahydrate]
Ultramarine blue
[C.I. Pigment Blue 29]
Urea
Vanillin
[Benzaldehyde, 4-hydroxy-3-methoxy-]
9

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Nonfood
Use

CAS Reg. No.

1318-00-9
8028-52-2
50-81-7
1406-18-4
N/A
N/A
N/A
N/A
8006-95-9
92129-90-3
8042-47-5
68917-75-9
13983-17-0
N/A
11138-66-2
68876-77-7
1318-02-1
68989-22-0
12063-19-3
1314-13-2
557-05-1

Chemical Name
Vermiculite
Vinegar (maximum 8% acetic acid in solution)
Vitamin C
[L-Ascorbic acid]
Vitamin E
Walnut flour
Walnut shells
Wheat
Wheat flour
Wheat germ oil
Whey
White mineral oil (petroleum)
Wintergreen oil
Wollastonite (Ca(SiO3))
Wool
Xanthan gum
Yeast
Zeolites (excluding erionite (CAS Reg. No. 66733-21-9))
Zeolites, NaA
Zinc iron oxide
Zinc oxide (ZnO)
Zinc stearate
[Octadecanoic acid, zinc salt]

Food
Use1/

Nonfood
Use

1/ Inert ingredients eligible for FIFRA 25(b) pesticide products having tolerance exemptions under one or more of the
following sections of 40 CFR Part 180: 910; 920, 930, 950(a), 950(b), 950(c), 950(e), 960

Revised 12/20/10

10