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Lecture 15
NC State University
The everyday pH scale
To review what pH means in
practice, we consider the pH
of everyday substances that
we know from experience.
pH + pOH = 14
Add the acid and conjugate Add a strong acid to the weak base
base to the solution in a (or vice versa) until the desired
defined proportion. proportion [A-]/[HA] is obtained.
Buffer strength
The ratio [A-]/[HA] should be as close as possible 1:1,
but the amounts may vary. To make a stronger buffer
you simply need to increase the amount of each
component. Lets investigate.
Added [OH-] = 0
Understanding the titration curve
Suppose we want to make a buffer by titrating [OH-].
We cannot use the H-H equation initially. We do not know
the concentration of [A-]. Instead at this initial point we will
use the other form of the
equilibrium constant and
make an ICE table.
Added [OH-] = 0
Understanding the titration curve
Added [OH-] = 0
Understanding the titration curve
When we have a buffer we can use the Hendersen-Hasselbach
equation. This is nice since it is the simplest treatment of the
acid-base equilibrium. In the case shown we have pH = pKa.
Buffer region
pKa1 = 3.14
pKa2 = 4.75
The enzyme does not change the equilibrium, but it accelerates the
Rate of reaching the equilibrium on each side of a membrane.
Acid/Base Mixtures : Reactions
Total volume = 25 mL + 35 mL = 60 mL
Excess reaction
Species HCl H+ Cl-
Initial 0.008 0.0 0.0
Final 0.0 0.008 0.008
Examples: Strong acids and bases
What is the pH when 25 mL of 0.30 M HCl are
added to 35 mL of 0.20 M NaOH?
Recognize that both HCl and NaOH are strong acid/base,
respectively. Therefore, rather than find the equilibrium
constant, we assume that the reaction goes to completion.
In this case we find the limiting reagent which is NaOH.
Total volume = 25 mL + 15 mL = 40 mL
Excess rxn is
Species NaOH Na+ OH-
Initial 0.0313 0.0 0.0
Final 0.0 0.0313 0.0313
use rxn table
goes 100%
calc pH or pOH
Strong Strong
Acid Base
Weak Weak
Acid Base
Examples: One strong and one weak
What is the pH when 50. mL of 0.25 M NaOH are
added to 40. mL of 0.20 M HF?
Examples: One strong and one weak
What is the pH when 50.0 mL of 0.25 M NaOH are
added to 40.0 mL of 0.20 M HF?
Total volume = 50 mL + 40 mL = 90 mL
Species HF OH- F-
Initial 0.0888 0.139 0.0
Difference -x -x x
Final 0.0888-x 0.139-x x
Examples: One strong and one weak
What is the pH when 50.0 mL of 0.25 M NaOH are
added to 40.0 mL of 0.20 M HF?
Step 4. Solve for x
Examples: One strong and one weak
What is the pH when 50.0 mL of 0.25 M NaOH are
added to 40.0 mL of 0.20 M HF?
Step 5. Calculate OH- and pOH.
Strong Strong
Acid Base
use rxn table
goes 100% Weak Weak
buffer : H-H Acid Base
base : pOH
Examples: One strong and one weak
What is the pH when 25.0 mL of 0.40 M HCl are
added to 40.0 mL of 0.30 M NH3?
Examples: One strong and one weak
What is the pH when 25.0 mL of 0.40 M HCl are
added to 40.0 mL of 0.30 M NH3?
The total volume is 65 mL so the final concentrations
are:
[HCl] = 25/65(0.40 M) = 0.154 M
[NH3] = 40/65(0.30 M) = 0.184 M
In this case the [HCl] < [NH3] so this will make a buffer.
Assume that the strong acid reacts completely then at
equilibrium we have:
[NH3] = 0.184 0.154 M = 0.03 M and [NH4+] = 0.154 M
Examples: One strong and one weak
use rxn table
goes 100%
calc pH or pOH
Strong Strong
Acid Base
use rxn table use rxn table
goes 100% Weak Weak goes 100%
buffer : H-H Acid Base buffer : H-H
base : pOH acid : pH
Examples: Weak acid and weak base
For a reaction of a weak acid and a weak base
we need to calculate the equilibrium constant
from the known Kas. We take the example of
ammonium acetate.
for ammonia
Examples: Weak acid and weak base
Therefore, the overall equilibrium constant for
the reaction is
Weak Weak
Acid Base