Professional Documents
Culture Documents
! Subject
! Display
! Reporting
Visual Systems
Economopoulos TL. etal. Journal of Digital Imaging, Vol 23, No 4 (August), 2010: pp 399-421
Image Fusion
Bone scan images acquired at varying time points. Bone scan images after a histogram matching technique.
Jeong CB. Journal of Digital Imaging, Vol 24, No 3 (June), 2011: pp 424-436
Acquisition variation
Variation in Protocol labels for Brain MRI study.
! Filters
Variation in CT Number Obtained for Three Scanners
1.200
1.150
• Reconstruction
1.100
• Post-processing
Electron Density
1.050
Soft Tissue
1.000 ! Noise corrections
0.950
0.900
! Compression
! CAD
0.850
0.800
-150.0 -100.0 -50.0 0.0 50.0 100.0 150.0 200.0 250.0 300.0
CT Number
Display
! Hanging protocols
! Efficient reading
! Multi-spectral
comparison
! Serial comparisons
! Data visualization
! Display characteristics
! Atlases
Display - Atlas
Wang KC. Journal of Digital Imaging, Vol 24, No 3 (June), 2011: pp 507-515
Storage and Transmission
! File format variations
• DICOM (clinical)
• tiff, gif, jpg, zvi, lscm…
• pdf, xml, doc, bmp…
• Proprietary
• Compression
! Recall needs
! Metadata
! Data organization
! Sharing
! Research
! NLP
! Integration of ontologies
! Creation of domain specific
ontology
! Integration into reports: AIM
RadLex - RSNA
http://www.rsna.org/radlex/
! CIIP
! ABII Certification
Process
! Educational materials
! Journal, technical
publications, on-line
materials
! Networking community
Research versus Clinical
Clinical Trials as Research
http://qibawiki.rsna.org/images/d/da/Why_QIBA_CT_specifics.pdf
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Measurement Variability in the
Assessment of Part-Solid Lung Nodules
OBJECTIVE
K. GARG, PI
a b c
Invasive Adenocarcinoma. Axial CT image (a) shows a part solid nodule in the left
upper lobe. Corresponding sagittal CT images (b) and (c) show automated estimation of
the volume of solid component (1.188 ml) the entire lesion (8.312 ml) . In this case, if
tumor size were measured only by the invasive component, the size T factor would
change from T2a to T1a
! Phantom Scans
! Scanning parameters identical to those for human subjects, performed on
both Siemens 16 and Siemens 64 CT systems.
! Imaging of Lungman phantom with synthetic part-solid nodules from Dr.
Nicholas Petrick (1A Group). Performed on the Siemens 16 and Siemens
64 CT.
! Evaluation of synthetic nodules using same metrics as for human subjects.
! Imaging of ACR phantom to assess noise and spatial resolution, for
comparison with data from Dr. Charles Fenimore (1C Group)
Measures
! Analysts
! 4 radiologists, repeating each measurement
! Software
! Vitrea 3D volumetry
! Phantom calibration
! Intra- and Inter-observer variability
! Metrics Whole Solid Component Low Density
Lesion Component
Volume Volume Volume (Derived)
Mean CT Density Mean CT Density Mean CT Density
(Derived)
RECIST RECIST RECIST (derived)
NCI-QIN Bioinformatics
! Develop specifications for research archive
! Central archive, access control
! Support research and clinical file formats
! User interface
! Maintenance, documentation and support
! Open source, user community support
https://wiki.nci.nih.gov/display/CIP/Analysis+of+the+available+bio-imaging+archiving+tools
C-TRIC Web Site