Thecaaeutic inex 8 2. This is the: - Idiosyncratic effect C. Tolerance _D. potency route: ‘FOCtION of unchanged drag renching. the systemic Graaation following er A. Absorption se 3. In this BL First Pass Effect C. Bioavailability D. Bioaquivalence disease to Geter en’ “08 Sooner rs adm bes eh eee phase3 —_D. phase 4 ee ‘Cinical phase of drug development, the effects of the drag as 3 function of dosage Se ey nts, 5. Tha ean ppraee 2 pees 3 D. phase 4 is a ‘of partial seaures ano WEST itor of GABA aminctrensterase and is useful in the trentment vigabatin 8B. tiagebine motrigit . gabapentin 6. Action of Insulin in the iiver: cae C, C.lncrease ketogenesis “gluconeogenesis B. increase giyconenclysis increase: 7. Most comenon adverse effect of insulin: A. twasatvcemis 8. allergy —_C. lipodystrophy D. bleeding 8. Effect of digitalis in the AV node during . A. prdlanged PR interval BAY blockade C. bradycardia D. protonged QT interval 9. Immediate metabcic precursor of depamine that penetrates the blood-brain barrier: carbidopa C.selegiline —D. Ropinarole 10. The following are true of a (A. causes reversible blockade of alpha receptors C. significantly reduces bised pressure In supine individuals D. stimulates histamine (H,) acetylcholine and serotonin receptors 11. Antiarrhrythenie drugs that prolong effective refractory period by protonging action potential duration: A. Bers BBretvium — C. Esmolol_D. Lidocaine 12. Artiarrnytmic of cneice for suppression of recurrences of ventricular tachycardia & fibriliation after ‘termination of the arrhythmia by on: : 8B, Esmolol D. Procainamide A 13. ‘The most serious toxic reaction ta lecal anesthetics is: C. nystegmus ‘B. metabolic 2cdesis 0. tunit-cignic convulsions £4. Lithium’s most common side effect/si A nical pyoatnyroasm ©, iver oe peyphagia 15. Mase important unwanted effect of antipsychotics secondary to relative cholinergic deficiency: ‘A. Akathisia 6. Parkinsonian syndrome C, Tardive dyskinesia —_O. Perioral rabit syndrome 16. Blocks norepinephrine & serotonin reuptake purnps which are the “the off switches” af amine A. 9 benioliors Bie, oon Du batarecyctec. 17. Drug interaction of older MAO inhibitor with tyramine ingested in food: ‘A. depression B. Hypertensive reactions C. hypotension D. maria 18. The following are sites of the major Classes of anti-hypertensive drugs, except: ‘Sympathetic nerve terminats . Hypothalamus B. S-receptors of jurtagiomerviar cells that release rennin D. Vasomotor center 19. The following are the Geterminants of vascular tone, except: A. Increasing CGMP B. Increasing cAMP in the vascular cells 5. Stabsizing or preventing depolarization of the vascular smooth muscle cell membrane 2D. The foliowing are the pharmacodynamics of nitroglycerine, except:23. This agent inhibits yascent pestcteptnces Seep thesis by binding firmiy to the O-Ala- -p-aia terminus of" A. Cycloserine 24. A potent inhibitor 8 Vancamcin ©. Teicoplanin 0. Bacitracin = bacterial OF microbial proten Sintec ings revrsbiy tothe 50'S sun of eet sae mean a rye 25. These agents, 8. nec. Amikacin OD: PanicliNg en and ‘when. ernn ound to caldum genosited in newly formed bone or teeth i YOUNG Suoes ht atmnanped 120 be deposited in te fetal teeth, leading to fluorescence, 26 Asie omy & CTetranictines D. Aminegivcosides 0 by uasunal meter fo ya crcines gine and 5 amunosaicyiate and is widely », A, cee es B. oe ee eo ones i . Sulfamethoxazole "Sn ees Sto reyes arose a mare ee of a hormonally active SOS: act . AN antifungal i Tilostane —_C. aminoalutethimige 20. an An kng! cae ee wns Sn Seno ere oo gonad Benloagh 8. ©. mitotane 29. Tipe ey wd mae ALN, Gara and glucnoricrd act A. aldosterone 8. Deaxycortisone D. Cortis 30. A partial ‘gonist at estrogen receptors inthe cE eae rater in women by stimulating tamoxifen B. clomiphene. Danazol D. Mifepristone: 3i. An ‘ntinorogen that prevents synthesis of dinydrotestosterone by inhibiting the activity of 5-0 A. spinnolactone 5. Cypretefine C. finasteride — D. Flutamige 32. ae are effects of promotes blood cnagustilty 33, MazzoUi reaction, as an adverse effect is seen with the use of this agent, characterized as amen ae rashes us to the retsase of foreign parties from the dying micrufieriee: 8. qethyicarbamazing 34, a declarng muse Bach oO sed san aera 8 MeDEGAOE i he LAK of ascariasis and curate 8. nyrantel pamoate reciaieeal BD. primaquine ‘A. piperazine - e Du primaguene 36. The drug that could azaslerate antithrombin activ resulting to blockade Of the Coagulation cascade wai Methimazole 8. pace ‘most widely used to control te symptom of hyperthyroid? Which beta blocker “Hees: er ofthe object Grog, C. Decrease efficacy of object A. Decrease B. reversible inactivation ofthe enzyme Ce ees exe DY "he Susi ee of GABA receptors eh Direct be duration of GABA — gated chorde channel opening rene Lgrazeines the che treatment of secures i ned because ofthe «2 Thee ooo B. folerance © C. Slow absorption D, low therapeutic index ~ 2 a a ceactng mre a te Socal parormonce and ever sod “hele geting oder. He aso a tobacco taser. What is the next best @rvB 11S venlafaxine Citalopram = C. A Bupropion 8 ee short Intervals 3 cqurane D-taiainane A, Nitrous oxide ale ne enapaueal ESBS MSY given the ff, except: 45. R55 =~ year ol Frmale win Ore c.calcum ©. Calotonin ‘Aegonor Pir ee ee rtisons 47. Drug of choice for C. Dexamethasone DOO 48. The effet of ciecnnn mifepristone © laipieioe D. misoprostol Hethyistilbestral intake taken during pregnancy oF B. endometrial C. cervical polyp female infants: A. Aged patient 3. Ncohoigm C. HypogonadismD. Depression - Major machanism of action of aspirin as NSAID iS 7 COX inhibitor Chemotaxis inhibition ©. Doar - regulation of tt 55, Which of the foiowing i the drug of choice for inducing 1abor Methyl ergenovine —-C. Misoprostol D. Dinoprostone 54. The primer crsermoon ah cna ts St2 ‘A. Determine the safety of the drug __C. Determine the efficacy of the drug 'B. Ensure that there is no risk to the subject ©. Peni forthe welfiate oF Samet rug guide B. drugs that satisfy the health care needs of majority of population G_drwos with special oharmacsioaical properties ©. not to be used as an alternative to core drugs a &. 8. or of hepatic al CVESAA enzymes 39. The ures hapa recmrs roan er A ‘Gretam coupled B._ion channetiinked C. kinase-linked —D, nuciear G0. Hf 2 drug nas » high distribution velume, & indicates: A. itis highly bound to piesma proteins B. the drug is highly retained in the vascular compartment concentration will C. the plasma drug 64. The index of safety of @ drug decreases as the median toxic dose : B. increases and the median effective dose decreases €. and the madian effective dose decrease the median effective dose increase 6 wnat the major sorond messenger of Beta receptor activation that partons i Stra A. Ingsite! B_cAMP c hacacoio D, adenvin cyctase ‘are the drugs phenoxybenzamine and phentolamine useful (66. In. what condition en d B. migraine attacks D. benign prostatic hyperplasia 67. Acetylcholine acts by: ‘A. increasing adenylyl cyclase activity B. decreasing cGMP concentrations D. all of the abave 68.) Winch of te folowing anuhyaerersive ages Ms the sh documented evidence for prophylaxis against migraine attacks? A. pindolat Tate C. cionidine ‘D. prazosin 69. Which is a direct effect of nitrates when given in the usuai doses for the management of angina? My increased preload C. increased cardiac contractility 8. inerageed ofterkad D,_smooth muscle relaxation 70.4 coli fiend consis you regaring We sukabiy of he therapy ts doctor Nas prescribed So Severe hypertension. He complains of postural and exercise hypotension (“dizziness”), some diarrhea, and prablems with ejaculation during sex. Which of the following is most likely te produce the effects B,_quanethigine —C._ hydralazine ‘D. Captopril46: Comticasteroia ‘4h MOst potent anti-innammatory activity cortisone a. Degas ocean C. Dexamethasone D+ 1! 48. HERE, 2 mere c. creer SOR tts: 8. ‘erganovine ‘C. Misoprostol D. Dinoprostone: $4. The primary consideration in ail dinical trials is to & Suara so C. Onterine the afcacy ofthe doug B See era a ems sanmane DB. not RS be used as an altemnative io core drags 56. Which of the folowing ts considered 2 regulate drug A pseudesphadnins meperidine c. aree ocd -acit diethylamide (LSD) D. cocaine 57. Bienes mnt fava kana ang ea was ens. 8. pharmacosenctics €. posology —_D. ‘Biochemorphalogy ere mona are Jy st uct are te os penoeesanie a ie AW pheochromocytoma ‘essential hypertension 5. septa ata ori prone Rrpercisia 67. ncarycroine 25 by increasing adenyiy! cyclase activity {GMP concentrations ——D. alll of the above 68. Minch oe folowing ampere ape ose BER ocamered ever lr prophins ‘against migraine attacks? ‘A. pindolot C. Gonidine prazesin 62. yc erect eient af rte hen gen ne wu des ore ransgernt of nina? increased preload C. increased cardiac contractility B dncreseed afterioed ‘D._smooth muscle relaxation Li ibon retires el op fon ‘the suitability of the therapy his dector has prescribed for severe hypertension. He complains of postural and exertise hypotension ("dizziness"), some diarrhea, and problems with ejaculation during sex. Which of the foliowing is most likely to produce the effects a vo aed fa A. propranciol —-B,_quanethidine hydralazine D. Captoprilably” - FeMUSe venous Bharmaccisgic of heart failure 15 HS B serie ear Pressure Action of agtatis in che treat increase in gp" Use ina women iabor mde: te folowing, EBCEET: B. uterine rupture C. fetal death : SPUD Which ae ait of tne Eros and PH? Tr. B._tanspentidase peptidyl tranferase 1D. aceryiase: safe, a tach malaria by blood smear. TH to have fal costvelfective, and ready avaliable agent to prescribe if this farmer has an allergy SO seandary to Mycoplasma, Chiamydia, and Rickattst3 imonia Ward of a tertiary hospital. Tuayorty of patients were treated with doxvcycting a i ng ADAG arate ba watcha out fr tase Bolan BASES renal faire photosensiti fetal bone defects C. superinfection 80. Wich of the folowing agents may prclpose 10 the development pseudornembranous colitis? erythr . D._cligamysio 81.4 patent with persistent ehvonic cough and fever had na response to adequate doses of oral penicilin. ‘Tree BE showed normal chest ndings, Further PE snowed bullous myringits. A chest Xray showed inhitrates, in the night lower lobe. Which of the following antimicrobials would be effective? ‘A. parenteral penicilinG — &._chiarithromycin C. vancomycin D. gentamicin 82.4°4 yor bid boy that has diarrhea and malnutrion was nated te have @ moced parasitic infection of ‘Ascaris, capilora phippinensis, and Trichur tchur. The single gent that coud be efective for A. pyrantel pamoate B._mebendazaie C. diethyicarbamazine 'D. niclosamide 83, Activated charcoal may be used to treat poisoning due to the following EXCEPT: A. 8. aspirin C. propoxyphene: ‘D._inon overdose 94. This herbal plant endorsed by the DOH is useful for the relief of muscle pain 'B. Akapuiko — C. Ts2ang ©. Sambong 85 eR oliow-up for tuberculosis, you noticed thatthe visual acuity of Vilma worsened from 26/20 On reid in both eves after only three weeks of HRPE. Your approach in management would be to discontinue: Bair of the 4 drugs and reintroduce one drug at 2 une c inamnide and refer to an ophthalmologist & Betambutol, reintroduce it after 1 week, and refer to an ophthalmologist se. Daemon ts administered intrevencusly for acute management of seizure, but when Given 26 8 ravi rated can cause a A. generalized seizure B, gingival hypespasia C. cardiac arrhythmia ——. GI disturbances. ‘87. Which anticonvulsant is Safe in pregnancy? A 8. C. valproic acid 50. wiints of tne following is 2:commen mechanism of action shared by all NSAIDS A ‘arachidonate release from the plasma membrane by ihibiting holipase inhibiting mast cell degranulation inhibition of prostaglandin H synthesis b. Inhibition of the the formation of leukotrienes by inhibiting lipoxygenase 189. The primary reason why aspirin has been displaced by NSAIDs as first choice drug of pediatric rheumatologists is because: is : ‘A. poor inflammatory effect and gastric irritation B. poor inflammatory effect and Reye's syndrome C. Jack of liquid preparation and high toxicity effect91. YOUr Patient requests sen her OWE Ts he to slp but wan pyoe ANE Ne a scat hypnotic tat not wl 9 el 50 tacaitate O'S request Your drug regimen acer whole operating room ex 92:tha! Process 8 Serer, noparbital pefore Sy which the amount of drug ts the body is reduced after gerministravon Bt A. Pharmacologic all, or only incidentally, with the receotor? it, se 94.8 ie antagonist. Partial agonist —_C. Dota Nas swallowed the contents of 2 bottes of a nasal decongestant ora earn ONS ive a adrenoceptor agonist. drug. aaa deen acavaven on OM patent ee Bronchadilation 8. Cardioacceleration. C. Vasodilation D. Mydriasis arteriolar 95.Ms. Green has severe hypertension and is to receive minoxidil. Minosidl is 8 Ne eftecs ‘vasoditator that does not act on autonomic receptors. When used in severe hypertension. would probably include: e cardiac contractility . Decreases mean arterial pressure and increased salt and water excretion by the KGney a Comp were hospltalized with symptoms thought to be due t0 ingestion botulinum toxin. The effects of botulinum toxin are likely to include: A. Bronchospasm B. Cyctoplegia C. Diarrhea D. Skeletal muscle spasms -. Parathion has which one of the following characteristics? A. It is less toxic to humans than mialathion B. Ibis more persistent in the environment than OOT . Tis purty absorbed through sién and lungs oan. ‘Brawn has had myasthenia gravis for several years. She reparts to the emergency department Complaining of rapid onset of weakness of her hands, cplopa, and ‘and difficulty swallowing. She may be ‘suffering from 2 change in response to her myasthenia therapy, ie, a cholinergic or @ myasthenic ‘qrisis. The best drug for distinguishing between myasthenic crisis (insufficient therapy) and cholinergic crisis (excessive therapy) ist Aatropine ——B. C. Physostigmine D, Pralidoxime 99. A 30-year-old man has been treated with several autonomic drugs for 4 weeks. He is now ‘admitted to the emergency department showing signs of drug toxicity. Which of the following signs Would eistinguish between an overdose of @ ganglion Blocker versus a muscarinic blocker? A, Blurred vision 8. Dry mouth, constipation 100°" Dilation of vessels in musde, Dry mcs of cutansnes vee, and postive HSU. a cnrontropc eects. onthe heat ae al cons €. Isoproterenol —_D. Metaprotereno! A, Acetylcholine 101. a ug of cc fr aap Sock D. Diphenhydramine A B, Epinephrine C. Atropine 102, Which af the following binds covalently to the ste specined? = cardiac § receptors D. Pindolot - receptors sob teri SCAT Sects a eam te th et X Ferrey ocks aneichawin IT at its receptor C. Beereases renin concentrabon In the blood 15. Increases sodium 2nd decreases potassium in the blood 104 Avisitor from another city comes to yaur office compiaining of incessant cough. He has diabetes and and has recently started taking a different antihypertensive medication. The most likely ‘cause of his cough is: A Losar nook D. Verapamit Decreased end-diastolic ventricular Increased cardiac force oe ‘A patient is admitted to the emergency department following a drug overdose. He is noted to have a severe tachycardia, He has been receiving therapy for hypertension and angina, A drug that often ‘Causes tachycardia is: mY si — -n ‘A. Diltiazem —B, Isosorbide dinitrate C. Propranolol .Verepamil©. Hleta-adrenccestors antagonists tiptoe te escocated with mthesis ° Calcium uptake by the sarcoplasmic reticulUr . An increase in ATP sy eee P» Aftinerease in srstotc intraceniar canes wee . A moaincation of he Seer near allure fequires: Giabetic renal disease and hyperkalemia and 2 Sluretc- "Which ofthe folowing agents would be EASY harmful in 2 paver With with severe & i D, Triamberene lia, Inflammation is ¢ ‘Hydrochiorothiazide ——_—C. Spironolactone Complex ussve reaction that indudes the release of cytokines, leukotriene, crochet Destides Prostagiandins involved in includes Tammatory processes ere proauced from saz Wseaiosenase 1 B.Cycooxygenase-2 LUpoxygenase __0.Phaspholinase A: Which of the ut NC fe lowe sare antes he Te one ONE outge ‘Successful therapy of heart failure with digoxin will result in which one of eee B lncreased afterload C increased aldosterone D.Increased renin secretion ne ‘When used as an antiarrhythmic drug, lidocaine typically: ingteases action potential duration c Increases contractility 45 tcf ong a ecg te of tt ae (OY ug, ‘One eftect that heaping aise Se mein te in comman is: nitroglycerin, we : A. Increased gastric acid secretion Co eeet stmulaion of cardiac contractile force B. Tachycardia (0. Postural hypotension 117. Nedocromil has as its major action A. Biock of calcium channels in lymphocytes , flock of mediator release from mast.cells . Block of phosphodiesterase in mast cells and basophils _D.Smaoth muscle relaxation in the bronchi 118. You are on your way to take an examination and you suddenly get an attack of diarrhea. An over- the-counter: 6 i C. Leperamide D.Dipnenoxyiate by: ‘Aminocaproic O.Wartarin 2 Reno errre honing pais o's rv effect and mechanism of action is accurate? 1. autos! scion nS inhibits reuptake of uric acid from renal tubular fluic ‘B. Etanercept antirheumatic action: inhibits dinydrooratate Gehydrogenase, the enzyme in ‘arteriosis of the newborn 121, A S2-year-old woman presented with intense pain, warmth, and redness inthe frst Use on her lft foot. Examination of fluid withdrawn from the inflamed joint revealed crystals of uric acid. In the treatment of this woman's acute attack of gout, the advantage of using indomethacin instead of is that indomethacin is Se ee ad aanter C. More hikely to prevent another acute attack ©. Less likely to precipitate sudden gastrointestinal bleedingreceive patent DES & probably should not A a RRnOTTONN baton can 8 etree, ana ‘and a history of alcohols - 129. Which of tre pe "S2C20n 8. Excessive weight gain Casi ato Sue A. # Second generation sutfonyiures? 130. Which of 3 C. olimesirige D. rosigitaZone otherapy In the weatnent of nef drugs is MOST ticely to cause hypogivenmmia when used 2 331. _ADatient needs anuiieue a, C. Migitot D. Rosigitazone : endocarditis, us sor ake pave, cature postive infective Neer Year The best a sa Ueauert for cave are at oss span Gaur the OS fe with: C. Meropenem .vancamyan A. Caspofungin ; ‘Nystatin 137," Sfimich of the following statements about fluconazole iS most accurate? ‘Ah. itis highly effecave in treatment of aspergillosis C. Ie does not penetrate the blood-brain barrier A. Abacavir . C. Oseamivir D. Enfuvirtide 139. Which of the ft js NOT an expected effect of muscarinic agonists instilled into the conjunctival sec? a Contraction of the smooth muscie of the ins sphincter. Contraction of the cliary muses B. Mydriasis D. Improves aqueous humor outfiow in the canal of Schiemm. 140, Nausea, voting, diarrhea, urinary urgency, Salvation, Sweating, cutaneous vasodilation and ‘constriction are caused by an overdose of: A B,Pirenzepine —C. ©. Pilocarpine 141. Th normal individuats and more s0 in patients with airway disease, the administration Of this agent ‘causes some bronchodilation and reduction in secretion: ‘Atropine B. Metacholine C. Carbachol 1D. Bethanechol 142. Tne.apet reves motion scenes 204s as effective as any more raceniy MtSHUCed aoenE Dut causes significant sedation and dry mouth. 8. Sconoiamine C. Talterodine D. Darifenacin ‘A. GABA B. Acetyicholine C. Glutamate D. 5-Hydroxttryptamine 1146, Which among the following sedative-hypnotic drugs has the fongest elimination nalf-life and is ingested as a prodrug that is hydrolyzed to its active form in the stomach? A. Alprazolam B. Lorazepam C, Qvazepam D. 147, The mast commen dose ~related adverse effect of valproic acid is: ‘A. hepatotoxicity 8. skin disorders C. cardictoxcity —_D. nephrotoxicity 148, E3, 35 yo executive often awakens early in the sleep cycie and could hardly go to sleep again. He may probably benefit from which of the following drugs? ‘A. Flurazepam: 8. Clorazepate C. pentothal —-—D. Zolpidem‘Scotema: minutes OY 8 EE for this. followed after around 30 MONET ug of aus Condition? Sours i untreated wich 152. YH, 62 B etothrerate aS Serng tom C. Toimetin _B. Paracetamol ‘se cons catenae mei mages erase mse a averse eects of tne arc aman O89 ) ty B.tsyérochlorothiazide Captopril D. Nifedipine 154, 6,8 yo femote tance ha Conic wt atm i ie wesrader Srtuncion ‘ut no edema: first Grug to be used for her are: ‘A. Br Blockers 8, Diuretics C. Catcium blockers 157. Chigroquine is effective in the treatment of nonfaiciparum and sensitive: causes which ‘OF the Relowing comenion side Seca? A. pruritus B. ‘slopes: 158. The common adverse effects of Quinine i treating ©. ACE inhibitors falciparum malaria but & . Which ef the following drugs 'S appropriate? . Pyrantal pamoate, Proziquante . Mebendazole ©, Metronidazole . i ‘pacterial cells interfering with the trarispeptidabion reaction of a wetpimazoie BE nyroidectomy ——_C. Iodine oP eanarans . 160 Thi ayent i @ prohormane that serves as 2 precursor to # numer metabotites, including i A calomimeticsA following Methimazaie hyperthyroidism o. 272. Whien of ne Seen sete! th rats exo 8 DT fF ERP " Scots dance es Se eorang og oo” . constant 176. At low doses, dobutamine receptor select ad act wil prearly res 1 bronchodiiation . ‘C.ditatation of renal bladder vessels: uterine 8. ‘contraction 177. Antiarrythmic with the most marked K-blacking effect A a D. verapamil A ine 8. ‘C. dopidearel 2D. ASA 479. Drug interaction seen with concomitant spironolactone anid ACE inhibitor use eee iniitatoes may decrease renal pertusion decreasing the action of spirenciactone in the collecting 8, Additive aftertoader effect oe eaerced vasodilating effect of AGE inhibitors because of inhibition of metabalism By spironolactone ‘180 The following art-hypertensive drug shouls be used with caution In patients on potassium-sparing diuretics 8. hydrochlorthiazide C.verapamil D. methyldopa 1 ee ilation of bradykinin due to ACE inition js responsible for these adverse effects EXCEPT: A. cough s ©. bypobansion D. hyperkalemia 102 The sosence of reflex tachycardia with tne use of ACE inhibaors due to A. dawnt Sen pecphersl vascular restance C_ enhanced sympathetic activity . inhibition of RAA system assem aaverse effect of nitrates can be prevented by providing nitrate-tree interval between lass | antiarrhythmic drug has marked negative inotropic 36 resin gti wth Peat are action and therefore should not be A disopyramide C. procainamide 197. The risk of Tors8des des pointes is highest wth the use of D. lisocaine ‘A. sotalol 5. breton C. Meesinide 188. Drug-induced lupus & an adverse effect of D. amiodarone A. scorainamne, B. disopyramide —C. amiodarone D. - 199, Xl yer a maths Sete aamvapaty and ov gain. We complains oa ‘vomiting ond ¥ © has digitalis toxicity. Which of the foltow nen © nesses and A Furosemide emmige - 8, spironolactone. ©. Catvadiiot ey D. captopntA. Phenobarbital _ valproic acid ¢. Carbamazepine agents: 196; Ore ysitenson a ost common wt ele HS apie D. enhancement of post-synaptic GABA receptor current 5 200 Band te trachoma of action, the folowing soumacronal i NOT selectvell LOT, ‘A. piperacillin 6. 8 201, Which of the following ir effective against both aerobes and anaerobes? ‘A. metronidazole © oo eee irhastic i requenty sssonated with 6 nerve damage in the offspring Hf given to pregnant "women, thus classified under pregnancy risk category O. A. Clarithromycin Tetracycine Streptomycin 203" Maculopapulor rash with this antic 1s non-immunciogic i nature and does not preclude the use ‘of chemically related antibiotics in the future: A. Erythromycin B. amoxicillin C. Cefalexin D, cotrimoxazole 204A 18 year old college student came in because of headache, fever, chills and photophobia, Thick and thin snowed F, vue, Ta orl df cones te ood o claaenn A, Quinine mefioauine . Prienaquine Rachiorequing Mapendazole is effective against the folowing parasites EXCEPT 8, . necator emericanus B. ascaris lumbricoides D. trichunis trichiuria following antiviral agents DOES NOT require activation by phosphoryiai 208, syns one a roves nace tion and & directly inhibits C. acytiovir The @.toscames ‘A. SLE like syndrome CHeniolysis ‘old male receiving anti-TB treatment develops is, ©. hepatitis 28 eoiag could nave caused * mono-articuiar arthrits, Which of the ‘ethambutol 8. rfamoicn + 8. c emerven 209. Mraiowing, the machaniam of actions of this o ie. ‘this. ember syrinests ‘antifungal does not involve inhibition of cell A, Terbinafine: B.flucwosine C.F 210. Aromatase inhibtor used in the treatment of breast a < Y Which of the following statements is TRUE BD. Jeuprolide 211 We jucoccsticoids (GC? ‘eearaing the Gre genomic pharmacodynamic action of 3RE) ‘renscription wuceUS where it binds SR era cell citnaiagm a etn Gene: ber Fespanse element = D. gnseofulvins aah muscarinic alpha srenergi receptor C. leukotriene stcentor 0. nicotinic ‘The newromuscular blocker succinyichaline acts by: ‘A. antihypertensive. antigiaucoma C.antidiarrheal Dall of the above 223, Non-benzodiazepine that has affinity for the Bestzodiazepine receotors, A ‘8. Midazolam c. D. All of the above 224 eee ypnotc with low soll and penetrate the bra siowhy Incieear, 8. C. Temethadione 'D. Valproic acid 22st the following drugs/substance of abuse are CNS stimulants, EXETT C. Cocaine ie Biperiden . An ‘opioid causes mydriasis instead of the characteristic miosis teoscy: = S Meperidine C. Methadone D. Morphine of opioid . 2391" wach of tes group of Ussues woul be the frst to take up appreciable amounts afi A. Fat 8. Muse G. Vesseicrich Deve 232. Fa cque-adies saben oven the gan subtest contol he wihdraval @. Meperidine <_ Methadone barbiturate A B. Hepatic! ‘thiopental is largely determined by: 70d, "weea ag ets cng 08 Kemer e its receptor on ‘B_ inhibit airway. mucosal inflammation & cohance bronchial reactivity 3 "anb-inflammatory . release of ‘i A ae ag that reves Sean oe BO ast eer est ne wed toe SAspicin Sopecds OMe C pepe ee Oe D. all.of the above:renal toxicity asthe gy vopraceon BCs Do pool of urate 2° ‘Dp. reedty BY Toda tssue are Wen 4 « C. Nifedipine 9. amiostpi to: 1p. Bithional 8. Sivonen Cbrate Metrifonate iment zane Most due to: ic impas fost ofthe Serious adverse tects of Penclins are GUE Cy; < _-D. Hepati B. Hypersensitivity reactions 246, tne elon oT re ay Rea ‘EXCEPT: ci, oa . 240 Th fr Try conrad young ono wos mil HY reen colo assessment can not be adequately w 250. fe eb ncn on ce ‘Staphylococcus aureus: 8. Mupsocin C. Polymycin B sulfate —_—. Bacitt 251. ay et ane ree ae ens mer “patients whose gonococc| ‘are resistant to other drugs is: A. Offoxacin 8. Tetracycline C. Doxyeycline ‘Spectinomycin 252. Ca an Oar sn lng oe Wertrincan be reversed by: ‘A. discontinuance of the drug C. administration of fresh frozen plasma ration of Vitamin K all of the above 253. ‘The amount of elemental ron per 325 mq eablet of hydrated ferrous sulfate is mg: we 8.65 c. 60 therapy is: pereperer a Thyrogloculin traceptive effect largely through: Cane alteration in the motility of the uterine tubes ‘of @ mucoid cervical secretion. enhancement of the ruptu 256, The most dangerous complication of Thioamides is: re of the ovarian follicle tupus-like B hepatitis ©. agranulocytosis 2 ae te Cen etolative dermatitis C. Tamoxifen 258 8, Metformin C. Repagiimide rene epeen ica a the Naina’ Guat Acarbose B.2HRZ/4HR C. QHRZE Program i meen aunty f a abserytn, ‘distribution, metabotisin or Dd. SAREES Pe consists Of Se 8. Pharmacokinencs Sxcretion of drug is known as: es Fegarding the 85 drug 8 at a di A Sra Aas 2 oer ey tan Ong 8” CE ‘dose of 1000 mg. One of the B. Drug B has 2 greater San Org A c 264. Drugs with very high volume of distributi D. Brug B is ‘A. are-completely retained within the vy, 8. Scar compartment mare potent than Drug a & sex besrogeneity Sonia have ‘9 Blood287. Selective coer ssiates an act Se ¢2 ibRor® have no: COK-2 nian gare EE to various ogeRS p_alotine ee iectve D. renal toxicities heart 269, Muscles of the blood c ia — ae ca sels Seti seages pation come A-Nitrous oxides 0.47 Reserpine 8. Enfiurane=1.40 ¢. Halothane=2.30 270; Reserpine blocks tis step in adrenergic WrSTiSSO: 8. release of the neurotransmit — A — 271. 2A yepr old male was brsoutt to the emergency raom afer having allegedly Grane PTE, constricted pupls, was noted to have ealvation and sweating, wheezing, orn? C. opiate D. ephedrine een acme . noncompetitive antagonism 274, Conaperss as Tore effects on the ff. receptors. A speak 8. alpha 2 C. beta 2 D. 275. Drugs tke ‘and disopyramide are useful in the treatment of: congestive heart failure B. status asthmaticus €. thy! 276. A 65-year old male was admitted at the A. Depress B. Prolong A-V conduction D. All of the above 276, Ai of the following are true of sodium nitroprusside EXCE "A. The gold standard for use in hypertensive crisis 8, Mechanism effects A parr the following antianginal agents és contraingicated in patients with ae . B. Diltiazem C verapamil nis with vasospastc * A Jetnyidopa 3s antihyperatensive agent exerts scsorbide angina: 261. Tycn stimulates centrally this receptor: ‘effect by conversion to alpha. A. alpha-2 8. alpha-2 ©. Beta norepinephrine ‘Aminopenicili D. Beta-2 and ‘ bar i nt on oar ne omoare to Peniitin G: 5: Have lesser tendency to cause hypersensitivity reaction D. Are resistant to B-lactamse 283, Clavulanic acid 1s added to Ampicilin in order to: ‘A. Prevent occurrence of diarrhea Ci the 200° Tre tmost common side effect of erythromyaris; = Increase ie aby by increasing eyndrona Sastrointestinal tract, ‘Gastranetstioalueset Bred neck 2 95" Bacterial syneroism Is produced by the Pxeudornann 285 tetracycline and peniciin G ‘Blowing deus combination: AS Meh B. Tetracycline and chiorampheni cs rotoxicity 296, Ths antimicrobial drug may provoke ante g fetracycline and strep 267. This agent IS proven effects for infiven a, SNH bts A aid fone eccar prcn mE 288. This agent Paralysis Of the nema’ 225 36 a Gina —— * pean 269, Team B ° women SETS Imetronoidazoie: BENE Is also effective far amebic : smite ees ‘weatin : Mefloquin paliiats 290, TNS I 2 arti agony ATaCaaUne cM 7 Prima m breast cancer: DM 201, dene 5. Diathyistithesteroi ¢. Tamoxifen iteoristone h. Preparing nemnanced : s 2 Se cm Inhibiting ovulation 282, The mat common sie fect of aun ‘Actions dystrophy C. Insulin allergy D- Hypoglycemia 1 B.Renai 293. Actions ef Vit, D inciude: A. Antagonis im oof parathyroid hi _