PersonalCare

Geogard™ Ultra™ (patent pending)

Next-Generation Preservation

INCI Name: Gluconolactone & Sodium Benzoate Description

Geogard™ Ultra™ is a synergistic, patent-pending blend comprised of
Chemical Compound Breakdown Cas No. EINECS No. gluconolactone and sodium benzoate. What makes this preserva-
D-Glucono-1,5 Lactone 90-80-2 202-016-5 tive unique is the synergy between the two ingredients, allowing for
Sodium Benzoate 532-32-1 208-534-8
its broad spectrum efficacy. Typically, organic acids on their own are
Calcium Gluconate 299-28-5 206-075-8
too weak and often require a co-preservative or booster in order to
perform optimally. The gluconolactone in this blend works together
Key Product Benefits: with the sodium benzoate to act as an efficient preservative booster
– Global Approval (Including Japan) that is also non-GMO. Geogard™ Ultra™'s gluconolactone works by
– Broad Spectrum Activity slowly releasing gluconic acid over time, which helps contribute to
– ECOCERT Accepted and Soil Association Approved the preservation.
– Wide Applicability
– Bacterial/Fungal Control
Chemical Compound Breakdown Percentage
– Widespread Usage D-Glucono-1,5 Lactone 70-80%
Sodium Benzoate 22-28%
Calcium Gluconate 1%
PersonalCare
Geogard™ Ultra™
Next-Generation Preservation

Applications Moisturizing Cream

– Baby care – Hair gel Ingredient %W/W
– Baby wipes – Hand soap Water, deionized q.s
– Body Butter – Liptick/gloss Caprylic Triglyceride 2.00%
– Body wash – Lotion Sorbitan Monostearate 2.00%
– Conditioner – Make up remover PEG Stearate 1.50%
– Cream – Mascara Glyceryl Stearate 2.00%
– Deo/ Anti-Perspirant – Oil in Water Decaglyceryl Stearate 5.00%
– Eye creams/gels – Oral care UV absorber optional
Thickener optional
– Eye shadow – Powder
Preservative quantity varied
– Face Lotion – Shampoo
Total: 100.00%
– Face wipes – Suncare
– Facial Cream – Toner
– Foundation – Water in Oil Bacterial Counts (CFU/gram)
Sample# TestSamples Day0 Day7 Day14 Day28
1 Unpreserved 9.5x106 4.2x105 8.9x104 <10
Moisturizer
Recommended Use Level
2 Moisturizer 6.5x106 <10 <10 <10
0.75-2.0% with 1.5%
Geogard™
Ultra™
Recommended use concentrations for different product types
Initial Bacterial Inocula: 1.02 x 109
Product Type Concentration Geogard™ Ultra™
Creams type "organic" 1.5 - 2.0 %
Foaming Bath 1.0 - 1.25 % Fungal Counts (CFU/gram)
Shampoo 0.8 - 1.0 % Sample# TestSamples Day0 Day7 Day14 Day28
Hair Conditioner 0.6 - 0.8 % 3 Unpreserved 8.8x105 1.7x105 1.9x105 2.8x105
Hand Soap 1.0 - 1.3 % Moisturizer
Face Mask 1.0 - 1.5% 4 Moisturizer 2.1x105 <10 <10 <10
with 1.5%
Body Lotion 0.6 - 0.8 % Geogard™
Ultra™
*Recommended use concentration based on the Lonza‘s laboratory challenge test results Initial Bacterial Inocula: 1.02 x 109
data collection

Geogard™ Ultra™ can be used at 1.0 to 2.0 % as a stand-alone Anionic Protein Shampoo
preservative system, but can also be used successfully at lower Ingredient %W/W
levels (0.25% to 1.0%) when combined with other synthetic or natural Water, deionized q.s
Sodium Lauryl Ether Sulfate 15.0%
preservatives, preferably good bactericides. Lonza can recommend
Triethanolamine Lauryl Sulfate 10.0%
combinations upon request.
Cocomide DEA 3.0%
Anhydrous Protein 1.0%
Efficacy
50% Aqueous Citric acid pH adjuster
Microbiological Challenge Studies Preservative quantity varied
Studies were run using different concentrations of Geogard™ Ultra™ Total 100.00%
in various formulations to see efficacy against various bacteria,
yeast and fungi. All samples were inoculated at the beginning of the
study, sampled at 24 hours, 7, 14 and 28 days.

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Bacterial Counts (CFU/gram) Moisturizing Cream
Sample# Test Day0 Day7 Day14 Day28 Ingredient % W/W
Samples Water, deionized q.s
1 Unpreserved 9.5x106 4.76x175 1.06x108 2.0x107 Glyceryl Tricaprate 2.00%
Shampoo
Glycomul™ S 2.00%
2 Shampoo 5.2x105 <10 <10 <10
with 1.5% Pegosperse™ 1.50%
Geogard™ Aldo™ MS 2.00%
Ultra™
Polyaldo™ 10-1-S Pastillated 5.00%
Initial Bacterial Inocula: 1.02 x 109 UV absorber 2.00%
Thickener 2.00%
Preservative quantity varied
Fungal Counts (CFU/gram)
Total: 100.00%
Sample# TestSamples Day0 Day7 Day14 Day28
3 Unpreserved 6.6x105 2.0x105 3.0x105 1.7x107
Shampoo
Bacterial Counts (CFU/gram)
4 Shampoo 4.4x105 <10 <10 <10
with 1.5% Sample# TestSamples Day0 Day7 Day14 Day28
Geogard™ 1 Unpreserved 9.5x106 4.76x175 1.06x108 2.0x107
Ultra™ Shampoo
Initial Bacterial Inocula: 1.02 x 109 2 Shampoo 5.2x105 <10 <10 <10
with 1.5%
Geogard™
Ultra™
Cationic Hair Conditioner
Raw Material % W/W
Water, deionized q.s Fungal Counts (CFU/gram)
Polysorbate 20 0.5% Sample# TestSamples Day0 Day7 Day14 Day28
Lecithin 1.0% 3 Unpreserved 2.2 x 105 2.8 x 104 2.5 x 105 2.3 x 105
Distearyl Dimonium Chloride 2.0% Moisturizer
Cetyl Alcohol 2.1% 4 Moisturizer 1-3 x 105 8 x 101 <10 <10
w/ 1.0%
Cetearyl Alcohol 1.5% Geogard™
Lauryl Alcohol 3.1% Ultra™
10% Aqueous Sodium Hydroxide pH adjuster
Preservative quantity varied
Total: 100.00%

Bacterial Counts (CFU/gram)

Sample# Test Samples Day0 Day7 Day14 Day28
1 Unpreserved 8.3x106 4.8x177 2.4x106 9.0x106
Conditioner
2 Conditioner 3.5x105 <10 <10 <10
with 1.0%
Geogard™
Ultra™
Initial Bacterial Inocula: 2.7 x 109
Fungal Counts (CFU/gram)
Sample# TestSamples Day0 Day7 Day14 Day28
3 Unpreserved 6.6x105 2.0x105 3.0x105 1.7x107
Shampoo
4 Shampoo 4.4x105 <10 <10 <10
with 1.5%
Geogard™
Ultra™
Initial Fungal Inocula: 6.2 x 107

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PersonalCare
Geogard™ Ultra™
Next-Generation Preservation

Protein Shampoo Fungal Counts (CFU/gram)

Ingredient %W/W Sample# TestSamples Day0 Day7 Day14 Day28
Water, deionized q.s 3 Unpreserved 4.2 x 106 1.8 x 107 8.3 x 105 3.7 x 105
Sodium Lauryl Ether Sulfate 15.0% Conditioner
Triethanolamine Lauryl Sulfate 10.0% 4 Conditioner 4.1 x 104 2.0 x 102 <10 <10
w/ 1.0%
Cocomide DEA 3.0% Geogard™
Anhydrous Protein 1.0% Ultra
50% Aqueous Citric acid pH adjuster
Preservative quantity varied There is also a moisturization benefit on the skin with the Geogard™
Total 100.00% Ultra™. In the same moisturizing cream formulation used to
demonstrate preservative efficacy, Geogard™ Ultra™ produced a
quantitative moisturization benefit to the skin. Over a period of time,
Bacterial Counts (CFU/gram)
Geogard™ Ultra™ produced a moisturizing effect that was comparable
Sample# TestSamples Day0 Day7 Day14 Day28
to the use of 2 percent glycerin.
1 Unpreserved 7.2 x 106 4.0 x 108 3.3 x 108 1.2 x 108
Shampoo
2 Shampoo 6.6 x 106 < 10 < 10 < 10 Average Moisturizing Effect on 9 Subjects Over Five Days
w/ 1.5% 4.5
Geogard™ % Increase in Moisture over Five Days
Ultra™
4.0

3.5
Fungal Counts (CFU/gram)
Sample# TestSamples Day0 Day7 Day14 Day28 3.0

3 Unpreserved 1.2 x 106 4.9 x 106 7.1 x 104 2.1 x 105

Shampoo 2.5

4 Shampoo 1.6 x 105 <10 <10 <10

w/ 1.5% 2.0
Geogard™
Ultra™ 1.5

1.0
Hair Conditioner
0.5
Ingredient % W/W
Water, deionized q.s 0.0
1% Geogard™ Ultra™ 2% Glycerin Control w/o Glycerin
Glycosperse 0-20 – Polysorbate 80 0.5%
Lecithin - Alcolec F100 1.0% Treatment
Fig. 1
Distearyldimonium Chloride 2.0%
(Varisoft TA100)
Cetyl Alcohol - CO-1695 2.1%
Formulation Reccomendations
Cetearyl Alcohol -TA-1618 1.5%
– Compatible with a wide variety of formulation ingredients
Ethosperse LA-4 - POE 4 Lauryl Alcohol 3.1%
as well as most types of cationic, nonionic and
10% Aqueous Sodium Hydroxide pH adjuster anionic systems
Preservative quantity varied – Can be used effectively over a pH range of 3 to 6 and can
Total: 100.00% be added at both room and elevated temperatures
– It is recommended that it’s dissolved in the water phase or
Bacterial Counts (CFU/gram) a portion of water and/ or glycerin pre-mix prior to addition
Sample# TestSamples Day0 Day7 Day14 Day28 to the batch
1 Unpreserved 8.3 x 106 4.8 x 107 2.4 x 106 9.0 x 106 – Soluble up to 4% in ambient water; it can be easily dispersed
Conditioner
in glycols and alkyl sulfates
2 Conditioner 6.6 x 106 < 10 < 10 < 10
w/ 1.0% – Water soluble
Geogard™
Ultra

4
Solubility Data Global Regulatory
Solvent Soluble/Insoluble Europe
Water Dispersible – Max concentration of NaBenzoate is based on benzoic acid
Propylene Glycol Dispersible content
Glycerin Soluble – Max concentration of benzoic acid is 2.5% for rinse-off
Ethanol Insoluble – Max concentration of benzoic acid is 0.5% for leave-on
Mineral Oil Dispersible Japan
Vegetable Oil Insoluble – 1.0% total max. level of NaBenzoate
Silicone (Dimethicone) Insoluble US
Alkyl Sulfates Dispersible
– 5.0% total max. level of NaBenzoate
General
Additional Information – ECOCERT compliance, Soil Association approved
Geogard™ Ultra™ Synergy Study
While both the Gluconolactone and the Sodium Benzoate are
effective individually, the graph below demonstrates higher efficacy
due to the synergy between Gluconolactone and the Sodium Typical Properties
Benzoate contained in the Geogard™ Ultra™ Gluconolactone,% 70% Minimum
Sodium Benzoate,% 22% Minimum
Geogard™ Ultra™ Synergy Study - Bacterial Counts Appearance Free flowing, white powder
5.00E+06 Activity 99%
Recovery (CFU/g)

4.00E+06

3.00E+06

2.00E+06

1.00E+06

0.00E+00
Unpreserved Shampoo with Shampoo with Shampoo with 1.125%
Shampoo 1.125% GDL 0.375% NaBz GDL + 0.375% NaBz
Day 0 Day 7 Day 14 Test System

Fig. 2

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www.lonza.com

This document is an overview for professionals of certain scientific information on the subject ingredient and
certain scientific information on clinical and other trials with such ingredient. No claims are made herein for
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