Professional Documents
Culture Documents
ANTIMICROBIAL RESISTANCE
Dr.Hari Parathon,Sp.OG(K)
dr. Dani Rosdiana, SpPD
PENGABDIAN MASYARAKAT 2018
ERA PRE-
ANTIBIOTIK BEHAVIOUR AMR
ANTIBIOTIC ERA
HAI, MORBIDITY,
MISUSE MORTALIY, DISABILITY,
OVERUSE COST, ALOS
GLOBAL RESISTANCE of E COLI (ESBL (+))
GLOBAL RESISTANCE of Klebsiella pneumonia (ESBL
(+))
PREVALENSI MDRO 2013 - 2015
90%
80% 82%
MDRO di 60%
45%
55%
51%
K.pneumoniae
resisten seftriakson
50%
RSU Arifin 40%
41%
42% K.pneumoniae
resisten meropenem
Achmad? 30% 29%
41%
A.baumanii resisten
meropenem
20% 25% 26% 19% P.aeruginosa resisten
meropenem
10% 16%
11%
0%
2013 2014 2015
THE AMR IMPACTS
AMR - Reduction In GDP in 2050,
by different group
• Kegagalan terapi
• Ancaman pada operasi
canggih / kompleks
• Meningkatkan morbiditas,
mortalitas dan cacat
• Meningkatkan pembiayaan
kesehatan, menurunkan
GDP
NAP on AMR Indonesia one-health approach
Submitted to WHO library in May 2017
WHO regulation:
Global Action Plan National Action Plan
3
Reduce the
Incidence of
Infection
2 4
Surveylence & Optimise the Use of
ASP
Research3 Antimicrobial
1 5
awareness Inovation of new
and
understanding
AMR medicines,
diagnostic tools,
vaccines
THE PROBLEM
ANTIBIOTIC
USE Blood stream
more difficult to Pneumonia
treat UTI
more procedure SSI
high cost
ICU use
Failure morbidity
and mortality
HAI AMR
Healthcare Associate Infection
• infeksi yang didapat saat pasien dirawat di Rumah sakit.
(tidak sesuai dengan masa inkubasi penyakit)
• Incidence 3.4-12% (negara maju), 5,7-19.1% (negara
berkembang)
• USA 99.000 kematian/tahun
• Biaya $ 6,5 Milyard. (Rp. 84,5 T)
Bagaimana mencegah transmisi?
5. Develop the economic case for sustainable investment that takes
account of the needs of all countries, and increase investment in new
medicines, diagnostic tools, vaccines and other interventions
HIGH QUALITY HEALTH CARE
“the degree to which health services for individuals and populations
increase the likelihood of desired health outcomes and are consistent with
current professional knowledge.”