Professional Documents
Culture Documents
Pharmacology
Focus topic: Pharmacology Essentials
The following abbreviations indicate to the nurse that the drug is time-
released. These preparations should not be crushed or opened:
Dur = Duration
SR = Sustained release
CR = Continuous release
SA = Sustained action
Contin = Continuous action
LA = Long acting
Enteric-coated tablets and caplets are those coated with a thick shell that
prevents the medication from being absorbed in the upper GI tract, allowing
the medication to be absorbed more slowly. Spansules are capsules
containing time-released beads that are released slowly. The nurse should not
alter the preparation of these types of medications. The physician should be
notified to obtain an alternative preparation if the client is unable to swallow a
time-released preparation.
When preparing to administer medications, the nurse must identify the client
by reviewing the physician’s order. She must also administer the medication
by the right route. Many medications are supplied in various preparations. The
physician orders the method of administration. The choice of medication
administration is dependent on several factors, including the desired blood
level, the client’s ability to swallow, and the disease or disorder being treated.
The Patient’s Bill of Rights was enacted to protect the client’s well-being, both
mentally and physically. The client has the right to refuse treatment, which can
include medications. The nurse must document any treatment provided to the
client. Documentation of care given must be made promptly to prevent
forgetting any details and to ensure that another nurse does not duplicate
medication administration.
It is important to know that drugs generally have several names. The following
list explains these different names for you:
Beta adrenergic blockers are drugs that help lower blood pressure, pulse rate,
and cardiac output. They are also used to treat migraine headaches and other
vascular headaches. Certain preparations of the beta blockers are used to
treat glaucoma and prevent myocardial infarctions. These drugs act by
blocking the sympathetic vasomotor response.
Notice the syllable olol. When you see these letters, you will know that these
drugs are beta blockers.
The potential side effects/adverse reactions of beta adrenergic blockers are
listed here:
Orthostatic hypotension
Bradycardia
Nausea/vomiting
Diarrhea
May mask hypoglycemic symptoms
The following list gives you some nursing interventions for working with clients
using beta adrenergic blockers:
Notice that these end in cin, and many of them end in mycin. So, when you
see either of these syllables, you know these are anti-infectives.
Anti-Infective Drugs
The following list highlights some possible side effects/adverse reactions from
the use of anti-infectives (aminoglycosides):
Ototoxicity
Nephrotoxicity
Seizures
Blood dyscrasias
Hypotension
Rash
The following are nursing interventions you need to be aware of when working
with clients using anti-infectives (aminoglycosides):
Notice that all these contain the syllable pam, pate, or lam.
Benzodiazepines(Anticonvulsants/Sedative/Antianxiety) Drugs
The following list gives you some possible side effects and adverse reactions
from the use of this classification of drugs:
Drowsiness
Lethargy
Ataxia
Depression
Restlessness
Slurred speech
Bradycardia
Hypotension
Diplopia
Nystagmus
Nausea/vomiting
Constipation
Incontinence
Urinary retention
Respiratory depression
Rash
Urticaria
The following are some nursing interventions to know when working with the
client taking benzodiazepines:Monitor respirations.
These drugs are used as antiemetics or neuroleptics. These drugs are also
used to treat psychosis in those clients with schizophrenia. Some
phenothiazines, such as Phenergan (promethazine) and Compazine
(prochlorperzine), are used to treat nausea and vomiting.
Notice that all these contain the syllable zine
The following list gives you some possible side effects and adverse reactions
from the use of phenothiazines:
Extrapyramidal effects
Drowsiness
Sedation
Orthostatic hypotension
Dry mouth
Agranulocytosis
Photosensitivity
Neuroleptic malignant syndrome
The following are some nursing interventions to know when working with a
client taking phenothiazines:
The following list gives you some possible side effects and adverse reactions
from the use of this drug type:
Acne
Poor wound healing
Leukocytosis
Ecchymosis
Bruising
Petechiae
Depression
Flushing
Sweating
Mood changes (depression), insomnia, hypomania
Hypertension
Osteoporosis
Diarrhea
Hemorrhage
The following are nursing interventions used when working with a client taking
gluco- corticoids:
These drugs are used for their antiviral properties. They inhibit viral growth by
inhibiting an enzyme within the virus. Herpetic lesions respond to these drugs.
Clients with acquired immune deficiency syndrome (AIDS) are often treated
with this category of drugs either alone or in combination with other antiviral
drugs. These drugs are also used to treat herpetic lesions (HSV-1, HSV-2),
varicella infections (chickenpox), herpes zoster (shingles), herpes simplex
(fever blisters), encephalitis, cytomegalovirus (CMV), and respiratory syncytial
virus (RSV).
Antiviral Drugs
The following list gives some side effects and adverse effects that are usually
associated with this drug category:
Nausea
Vomiting
Diarrhea
Oliguria
Proteinuria
Vaginitis
Central nervous side effects (these are less common):.
. Tremors
. Confusion
. Seizures
. Severe, sudden anemia
The following nursing interventions are used when working a client taking
antivirals:
Tell the client to report a rash because this can indicate an allergic
reaction.
Watch for signs of infection.
Monitor the creatinine level frequently.
Monitor liver profile.
Monitor bowel pattern before and during treatment.
This drug type is used to help the client lower cholesterol and triglyceride
levels and to decrease the potential for cardiovascular disease. Notice that all
these contain the syllable vastatin. It should be noted that many
advertisements call these “statin” drugs. These drugs should not be confused
with the statin drugs used for their antifungal effects. These can include
nystatin (trade name Mycostatin or Nilstat). Table 1.8 lists some of the
cholesterol-lowering agents.
Cholesterol-Lowering Drugs
Here is a list of side effects and adverse reactions that could occur with the
use of cholesterol-lowering agents:
Rash
Alopecia
Dyspepsia
Liver dysfunction
Muscle weakness (myalgia)
Headache
The following nursing interventions are used when working with a client taking
cholesterol-lowering agents:
Dizziness
Insomnia
Depression
Diarrhea
Nausea/vomiting
Impotence
Muscle cramps
Neutropenia
Cough
The following nursing interventions are used when working with a client
takingangiotensin receptor blocker agents:
The following list gives some side effects and adverse effects associated with
histamine 2 antagonists:
Confusion
Bradycardia/tachycardia
Diarrhea
Psychosis
Seizures
Agranulocytosis
Rash
Alopecia
Gynecomastia
Galactorrhea
Following are some nursing interventions when working with a client taking H2
antago- nists:
Notice that all these drugs contain the syllable prazole and should be given
prior to meals.
The following list gives some side effects and adverse effects associated with
proton pump inhibitors:
Headache
Insomnia
Diarrhea
Flatulence
Rash
Hyperglycemia
Some nursing interventions to use when working with a client taking proton
pump inhibitors are as follows:
Do not crush pantoprazole (Protonix). Use a filter when administering
IV panto- prazole.
Advise the client to take proton pum inhibitors before meals for best
absorption.
Monitor liver function.
These drugs are used in the treatment of thrombolytic disease. These drugs
are used to treat pulmonary emboli, myocardial infarction, and deep-vein
thrombosis; after coronary artery bypass surgery; and for other conditions
requiring anticoagulation.
Notice that all these drugs contain the syllable parin and are heparin
derivatives. The client should have a PTT check to evaluate the bleeding time
when giving heparin. The antidote for heparin is protamine sulfate.
Anticoagulant Drugs
The following list gives side effects and adverse effects of heparin derivatives:
Fever
Diarrhea
Stomatitis
Bleeding
Hematuria
Dermatitis
Alopecia
Pruritus
Nursing interventions to use in caring for a client taking an anticoagulant
(heparin derivative) include the following:
These are some of the commonly given medications that allow you to utilize
the testing technique of commonalities. Looking at these similarities will help
you manage the knowledge needed to pass the NCLEX and better care for
your clients.
Here are some other clues that can help you in identifying drug types:
Schedule I: Research use only (for example, LSD). These drugs are
not medically safe to take and have a high potential for abuse.
Schedule II: Requires a written prescription for each refill. No
telephone renewals are allowed (for example, narcotics, stimulants,
and barbiturates).
Schedule III: Requires a new prescription after six months or five
refills; it can be a telephone order (for example, codeine, steroids,
and antidepressants).
Schedule IV: Requires a new prescription after six months (for
example, benzodiazepines).
Schedule V: Dispensed as any other prescription or without
prescription if state law allows (for example, antidiarrheals and
antitussives).