LBM 3

STEP 1

1. bleeding: -outing blood from perifer vascular cause traumatic or

leases from the vascular blood

-losing blood

2.petechiae: small red a purple spot in the body a proximacly want

until from millimeter and cause hemorrhage

-if the petechiae are press the color will not change

3.fever : reaction in the body because of infection.

4.hemoetasis: the mechanism by which loss of blood from the

vascular system is controlled by a complex interaction of vesell wall,
platelets and plasma proteins.

-contain two words Hemo and stasis. Hemo is blood and stasis is
maintance. Sequence of response to stop bleeding.

STEP 2

1. how the physiology of hemostasis?

2. How the patophysiologys of hemostasis?
3. What kind of hemostasis and explain!
4. How the etiology of the hemostasis?
5. What the factors of hemostasis?
6. How the mechanism of bleeding?
7. What the morphology of platelets?
8. How could ptechiae happened?
9. What are the releation between hemoestasis blood clotting?
 STEP 3
1. how the physiology of hemostasis?
There are three phase:
-primery phase: temporary phase contricsy and blood platelets or
trombosit
-secondary phase: trombosit relase reaction.
-tertiery phase: clotting factors activation.

2. How the patophysiologys of hemofilia?

Hemofilia are two:
1.hemofilia a:cause by deficiency of eight clotting activity
In bahasa: dikarenakan sintesis factor 8 menurun.
2.hemofili b: cause by deficiency of nine factors.

3. What kind of hemostasis and explain intrinsic or extrinsic factors!

in bahasa:
ada 13 faktor:
1.fibrinogen: protein yang disintesis dlam hati yang diubah
menjadi fibrin
2.protombin: protein plasma yg disintesisi di dalam hati
protombin menjadi trombin
3.trombo plastin: untuk mengaktivasi factor 7 untuk
pembentukan thrombin
4. ion calcium: diperlukan dlm seluruh pembekuan darah
5.pro akselerin: mekanisme intrinsic & ekstrinsic
6.fungsinya seperti pro akselerin:
7.pro convertin: diperlukan dlam mekanisme intrinsic
8.anti hemofilik: mekanisme ekstrinsic
9. plasma tromboplastin: mekanisme intrinsic
 10.stuart prower: mekanisme ekstrinsik dan intrinsik
11. antiseden tromboplastin plasma: mekanisme intrinsic
12. Hageman: mekanisme intrinsic
13.penstabilan fibrin: protein yg ditemukan dlm plasma dan
trombosit
4. What the factors of hemostasis?
ada 13 faktor:
1.fibrinogen: protein yang disintesis dlam hati yang diubah
menjadi fibrin
2.protombin: protein plasma yg disintesisi di dalam hati
protombin menjadi trombin
3.trombo plastin: untuk mengaktivasi factor 7 untuk
pembentukan thrombin
4. ion calcium: diperlukan dlm seluruh pembekuan darah
5.pro akselerin: mekanisme intrinsic & ekstrinsic
6.fungsinya seperti pro akselerin:
7.pro convertin: diperlukan dlam mekanisme intrinsic
8.anti hemofilik: mekanisme ekstrinsic
9. plasma tromboplastin: mekanisme intrinsic
10.stuart prower: mekanisme ekstrinsik dan intrinsik
11. antiseden tromboplastin plasma: mekanisme intrinsic
12. Hageman: mekanisme intrinsic
13.penstabilan fibrin: protein yg ditemukan dlm plasma dan
trombosit

5. How the mechanism of bleeding?

There is trauma on tissue, vascular rupture, the blood flows into
the tissue.
6. What the morphology of platelets?
Size is 2-4 mm, in the nucleus is absent or the sitoplasm colour is
light blue the age is 8-12 days.
7. How could ptechiae happened?
 In bahasa: terjadi perdarahan, dan hemostasis itu tidak bisa
mengatasi maka darah mengalir ke jaringan dan akan terjadi
ptechiae
8. What are the releation between hemoestasis and blood clotting?
The blood clotting the part of hemostasis, because hemostasis is
function from our body to flows of blood.
-Blood clotting one of the mecanisme of hemostasis.
Secara garis besar:
-perdarahan
-vaskular spasme
-konstriksi
-pembentukan sumbat platelet
-pembentukan pembekuan darah
-pertumbuhan pada jaringan fibrosa