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Hours
Course Basics
Credit Hours 3
Lecture(s) Nbr of Lec(s) 2 Duration 75 minutes each
Per Week
Course Distribution
Core Elective
Elective
Open for Student Students having taken Chem101 or Bio212 courses and graduate
Category students of Biology and Chemistry majors
Closed for Student
Category
COURSE DESCRIPTION
The Biophysical methods course is designed to provide undergraduate and graduate students an
understanding of detailed concepts of state of the art techniques involved in biological and
biochemical research. Students will learn the fundamental principles of these techniques and
details of experimental application in biological research. This course will particularly be helpful for
the students who are aiming to pursue Ph.D and perform scientific research. The topics such as
UV/IR spectroscopy, Mass spectrometry in proteomics, NMR spectroscopy in protein structures,
protein-ligand complexes & drug-receptor interactions, chromatography and calorimetry will be
covered with the aim to answer biological questions at sub-molecular level.
COURSE PREREQUISITE(S)
• Bio212 or Chem101
•
Lahore University of Management Sciences
COURSE OBJECTIVES
Assignment(s): 1 (5 %)
Quiz(s): 4 (5 % each)
Class Participation and attendance: 5 %
Midterm Examination: 35 %
Final Examination: 35 %
Examination Detail
Yes/No: Yes
Midterm Combine/Separate: Separate
Exam Duration: 2.5 Hrs
Preferred Date:
Exam Specifications: multiple choice, true and false and short descriptive questions
Yes/No:
Final Combine/Separate: Separate
Exam Duration: 2.5 Hrs
Exam Specifications: multiple choice, true and false and short descriptive questions
Midterm Exam
Recommended reading:
1. Introduction to spectroscopy by Pavia,
2. Introduction to modern liquid chromatography by Snyder and Kirkland
3. Mass spectrometry by Watson and Sparkman
5. Biophysical Tools for Biologists, Volume 1 (Methods in Cell Biology volume 84)
Author: John J. Correia, H William Detrich III
6. Physical Chemistry for the Biological Sciences, by Gordon G Hemmes
7. Introduction to Proteomics: From concepts to sample preparation, mass spectrometry data
analysis.
Author: Josiph Lovric
8. High resolution NMR spectroscopy
Author: Timothy Claridge
9. Fundamental of protein NMR spectroscopy
Author: Gordon S Rule and T Kevin Hitchens