Professional Documents
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Deoxygenated Blood comes from the Systemic Circulation via Superior and Inferior
Vena CavaRight AtriumTricuspid ValveRight VentricleSemi-lunar Valve
of Pulmonary ArteryLungsBlood gets oxygenated in the lungs and comes
back to the heart via Pulmonary VeinsLeft VentricleBicuspid ValveLeft
Ventricle
Semi-lunar Valve of AortaAorta Systemic Circulation.
Note:
Arteries are Red and Veins are Blue EXCEPT Pulmonary Arteries and Veins
Pulmonary arteries: are Blue and Pulmonary veins are Red
Conduction Pathway
histamines (vasodilators)
No cellular organelles
Contains hemoglobin
Specific Immunity
(from www.merck.com)
Lymphocytes are the most important type of white blood cell involved in specific
immunity. Dendritic cells, antibodies, cytokines, and the complement system
(which enhances the effectiveness of antibodies) are also involved.
Lymphocytes
Lymphocytes enable the body to remember antigens and to distinguish self from
nonself (foreign). Lymphocytes circulate in the bloodstream and lymphatic system
and move into tissues as needed.
Lymphocyte
Mature T lymphocytes are formed and stored in secondary lymphoid organs (such
as the spleen), bone marrow, and lymph nodes. They circulate in the bloodstream
and the lymphatic system, where they search for particular foreign or abnormal
Dendritic Cells
Dendritic cells develop from monocytes and reside mainly in tissues. Newly
developed dendritic cells ingest and break antigens into fragments so that other
immune cells can recognize them—an activity called antigen processing. A
dendritic cell matures after it is stimulated by cytokines at a site of infection or
inflammation. Then, it moves from tissues to the lymph nodes where it shows
(presents) the antigen fragments to T lymphocytes, which generate a specific
immune response.
Antibodies
IgG: The most prevalent class of antibody, IgG is produced when a particular
antigen is encountered again. This response is called the secondary antibody
response. It is faster and results in more antibodies than the primary antibody
response. IgG is present in the bloodstream and tissues. It is the only class of
antibody that crosses the placenta from mother to fetus. The mother's IgG protects
the fetus and infant until the infant's immune system can produce its own
antibodies.
IgA: These antibodies help defend against the invasion of microorganisms through
body surfaces lined with a mucous membrane, including those of the nose, eyes,
lungs, and digestive tract. IgA is present in the bloodstream, in secretions
produced by mucous membranes, and in breast milk.
IgE: These antibodies trigger immediate allergic reactions (see Allergic Reactions:
Introduction). IgE binds to basophils (a type of white blood cell) in the bloodstream
and mast cells in tissues. When basophils or mast cells with IgE bound to them
encounter allergens (antigens that cause allergic reactions), they release
substances that cause inflammation and damage surrounding tissues. Thus, IgE is
the only class of antibody that often seems to do more harm than good. However,
IgE may help defend against certain parasitic infections that are common in some
developing countries.
IgD: Small amounts of these antibodies are present in the bloodstream. The
function of IgD is not well understood.
Blood Typing
ABO and Rh Blood Typing
Cat Arteries
Cat Veins
Human Arteries
Human Veins
Structure of arteries, veins, and capillaries. (a) Diagrammatic view. (b) Line
drawing of a small artery (right) and vein (left), cross-sectional view.
Fetal Circulation
The small P wave accompanies the depolarization of the atria. The atria begin
contracting about 100 msec after the start of the P wave.
The QRS complex appears as the ventricles depolarize. The is a relatively
strong electrical signal, because the ventricular muscle is much more massive
then that of the atria. It is also a complex signal, in part because it incorporates
atrial repolarization as well as ventricular depolarization. The ventricles begin
contracting shortly after the peak of the R wave.
The smaller T wave indicates ventricular repolarization. You do not see a
deflection corresponding to atrial repolarization, because it occurs while the
ventricles are depolarizing and the electrical events are masked by the QRS
complex.
The P-R interval extends from the start of atrial depolarization to the start of the
QRS complex (ventricular depolarization) rather than to R, because in abnormal
ECGs the peak can be difficult to determine. Extension of the P-R interval to
more than 0.2 second can indicate damage to the conducting pathways or AV
node.
The Q-T interval the time required for the ventricles to undergo a single cycle of
depolarization and repolarization. It is usually measured from the end of the P-R
interval rather than from the bottom of the Q wave. The Q-T interval can be
lengthened by conduduction problems, coronary ischemia, or myocardial
damage. A congenital heart defect that can cause sudden death without warning
may be detectable as a prolonged Q-T interval
________________ 6. 10-12 μm; nucleus with 2-5 connected lobes; pale lilac
granules
________________ 9. 6-9 μm; round nucleus that is dark purple; sky blue
cytoplasm, no visible granules
________________ 13. ┐
├ Nicknames for neutrophils
________________ 14. ┘
________________ 1. ┐
│
________________ 2. ├ granulocytes
│
________________ 3. ┘
________________ 4. ┐
├ agranulocytes
________________ 5. ┘
2. A- ________________ __________________
3. B- ________________ __________________
5. Based of what you know about antigens and antibodies, what blood type is the
universal donor? ______ Explain.
______________________________________________________________
______________________________________________________________
________________________________________________________________
________________________________________________________________
E. Hematocrit
1. Define hematocrit.
________________________________________________________________
________________________________________________________________
3. Ron has a hematocrit of 47%. Is this within the normal range? (yes/no)
4. Janey has a hematocrit of 58%. Is this within the normal range? (yes/no)
1. Do the hematocrit and hemoglobin content of blood measure the same thing?
Explain.
________________________________________________________________
________________________________________________________________
________________________________________________________________
smooth muscle
endothelium
elastic fibers
collagen fibers
Circle True or False for the following questions. If false, underline and change
word(s) that are incorrect to make statement true.
7. The tunica media of veins is thicker than the tunica media of arteries. True or
False
8. The tunica media of elastic arteries contains more elastic fibers than muscular
arteries. True or False
11. Walls of veins are thicker than the walls of arteries of the same size. True or
False
12. Lumens of veins are larger than lumens of arteries of the same size. True or
False
B. Structure of Capillaries
Match the term to the correct description. More than one term may apply to each
description. Terms may be used more than once.
fenestrations
intercellular clefts
tight junctions
transcytosis
Circle True or False for the following questions. If false, underline and change
word(s) that are incorrect to make statement true.
C. Blood Pressure
Fill in the blank with the correct term.
6. Sounds of turbulent blood flow that occur when blood flow resumes in an artery
that has been occluded.
____________________________________________________
Circle True or False for the following questions. If false, underline and change
word(s) to make statement true.
7. The blood pressure gradient from the aorta to the capillaries is greater than the
blood
pressure gradient from the venules to the right atrium. True or False
8. Blood pressure gradient from the aorta to the capillaries is less than the blood
pressure gradient from the arterial end of the capillary to the venous end of the
capillary. True r False
9. Kate's systolic blood pressure is 115 and diastolic is 72. Her pulse pressure is
47. True or False
10. Scott's blood pressure is 126/83 and his MAP is 97. True or False
4. Recoil of muscular arteries maintains blood flow during ventricular diastole. True
or
False
5. Muscular arteries control the blood flow to different body areas. True or False
7. Blood pressure is higher in the supine position than in the standing position.
True or
False
8. Blood pressure decreases when going from a supine to standing position. True
or False
9. The greater the pulse pressure, the lower the pressure gradient driving blood
from the
aorta through the systemic circulation. True or False