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Presentation Outline:

- Review of the Anatomy and Physiology of the Brain

- What is Marijuana
- How Marijuana Works in the Body - References

THE BRAIN

Parts of the Human Brain

Parietal Lobe Frontal Lobe Occipital Lobe

P h y s i o l o g y o f t h e B r a i n

Corpus Callosum

Temporal Lobe Brain Stem Cerebellum

MARIJUANA

CANNABIS FAMILY

Cannabaceae contains two genera

Cannabis Humulus (hop plant)

Resin

used as a preservative and as a natural flavor in beer

CANNABIS

Known as cannabis, hashish, hemp and marijuana Source of: Strong fiber for rope and paper Nutritious fruit Industrial oil Medicine Cannabis Sativa is a fiber plant Cannabis Indica is a resin plant

CANNABIS

Male and female plants

Female plants are better resin producers

If female plant is not allowed to be fertilized, it flowe without seeds)

Greatest

but does not produce seeds sinsemilla (spanish for

resin producers

CANNABIS

Resin contains

Hallucinogenic compounds called cannabinoids

Delta-1

Tetrahydrocannabinol, also known as

Delta-1-THC THC

Major

active compound in the cannabis plant

CANNABIS
How is it used?

Leaves and flowering tips are dried

Smoked Consumed

as tea Mixed into food

Resin from flowering heads

Smoked Mixed

with tobacco Alcohol extract (cannabis oil) is mixed with tobacco and smoked

Quick Facts
1 joint = 20 cigarettes worth of chemicals. THC can also be stored in brain, lungs, ovaries, and testes. A mind-altering (psychoactive) drug THC is the main active chemical and is stored in fat cells for long periods of time (stored up to 30 days)

50 percent to 70 percent more carcinogenic hydrocarbons than tobacco smoke

There are over 2,000 chemical compounds in marijuana once it is lit.

The daily use of 1 to 3 marijuana joints can produce the same lung damage and potential cancer risk as smoking five times as many cigarettes

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Absorption, Distribution, Etc..

VERY lipid soluble

Very slowly absorbed when administered orally

3x the dose than for smoked pot Much longer lasting high

Smoking works way better

50% of THC goes to lungs Then to your brain

Absorption etc
Many of the compounds created during burning are also psychoactive Metabolized in liver mostly Other places too

Lungs if smoked Intestines if eaten

Metabolites are active

Cannabidiol blocks metabolism of THC

HOW IT WORKS IN THE BODY

mouse party

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References:

- The University of Utah Genetic Science and Learning Centre - www.worldofteaching.com - New York State Office of Alcoholism and Substance Abuse - http://learn.genetics.utah.edu/content/addiction/drugs/mouse.html

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Every form of addiction is bad, no matter whether the narcotic be alcohol, morphine or idealism. C.G. Jung

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