New Years Launch of Six New Technologies for Veterinary Clinical Pathology

Hematology Maureen McCullaugh Blood Gas Analysis Mick Garrett Endocrinology Joel Eluk, Penny Furney Flow Cytometry Inese Berzina, Amanda Lawler, Emma ONeill Multiplex Immunoassay Marianna Serra, Penny Furney Cellomics Margarida Domingos

Novel State-of-the-Art Biomarker Technologies at UCD UVH

Immunology
Hematology
Advia Guava

Cellomics
InCell

Immunochemistry Immunochemistry
Centaur MSD

Blood Gas Analysis

RapidLab 1200

Multiparameter Hematology System: ADVIA 2120

Biggest advance in hematology
technology for a generation in sensitivity, specificity and parameters added

Applicable to other body fluids eg effusions, BALF, CSF, & BM. Novel parameters eg reticulocyte size, maturity & Hb (most sensitive measure of Fe status), of platelet size & activation, of neutrophil myeloperoxidase, & of extracellular versus intracellular Hb Managed by Maureen McCullaugh

RapidLab 1200: Blood Gas Analyser

latest model in market place

delivers results for all parameters in 1 min maintenance-free, cartridge-based system LIMS interfaceable

Microsampler as little as 30 uL
Comprehensive analytic panel: blood gas (pH, pCO2, pO2); electrolytes (Na+, K+, Ca++, CI- ); Metabolic (glucose, lactate) Managed by Mick Garrett in out-of-hours / student lab Sample Port: Automatic sampling with a single port for syringe and capillary samples. Complete with automatic clot detection and clearance, short sample and bubble detection. Can backflush to clear so dont have to replace cartridge.

Centaur CP
automated Immunoanalyzer

latest model in market place

replaces Immulite

Numerous Parameters
Thyroid T4, T3, TSH Reproductive eg progesterone, estradiol, testosterone Adrenal eg Cortisol (dog) Cardiac eg troponin, CK-MB (dog, horse) Vit B12 and folate Insulin Skeletal Muscle troponin

Managed by Joel Eluk and Penny Furney

Guava Personal Flow Cytometer

smallest and easiest to use in

marketplace 2-angle scatter, 4 color

being developed for use for immunophenotyping of lymphoma and leukemia Assessment of cell viability
Managed by Inese Berzina, Amanda Lawler, and Emma ONeill

MSD 2400
automated mulitplexing

immunoanalyzer latest model in market place for high throughputting, needing microvolume testing (25 uL vs 150 uL), needing mutliplexing assay development possible panels of mulitple cytokines and chemokines cardiac panel of biomarkers reproductive hormones
Managed by Marianna Serra, Penny Furney

High Content Analysis & Hormesis

Automated microscopy Live-cell, image analysis Real-time, kinetic, multiplex Structure & function

96-well plate in incubator Single cell, populations, well l Intracellular location Managed by Margarida Domingos