Professional Documents
Culture Documents
Nada Al-Zahrani
Leukocytes, the only blood components that
cubic millimeter
Normal response to bacterial or viral invasion.
Granulocytes – neutrophils, eosinophils, and
basophils
Contain cytoplasmic granules that stain
Typical bi-
lobed nucleus.
Basophils account for 0.5% of WBCs and:
Have two or three nuclei connected via
chromatin strand.
Have large, purplish-black (basophilic) granules
that contain histamine
Large,
basicstaining
granules
shaped
(monocytes) nuclei.
Lymphocytes account for 30% or more of
WBCs and:
Have large, dark-purple, circular nuclei with a
thin rim of blue cytoplasm
There are two types of lymphocytes: T cells
and B cells
T cells function in the immune response
B cells give rise to plasma cells, which produce
Small antibodies Large
lymphocyte
lymphocy
te
Monocytes account for 6% of leukocytes.
They are the largest leukocytes
They have abundant pale-blue cytoplasms
They have purple-staining, U- or kidney-shaped
nuclei
Neutrophils: 2500 _ 7000/ cmm 60%
1. AIDS / HIV.
2. Severe bone marrow failure.
3. Some viral infection.
Monocytosis:
Increased absolute no. of monocytes.
Causes:
1. Protozoal infection.
2. Chronic bacterial infection.
3. Chronic myelomonocytic leukemia.
Monocytopenia:
Decreased absolute no. of monocytes.
Eosinophilia:
absolute increase in eosinophils.
Causes:
1. Helminth infections.
2. Allergic conditions.
Eosinopenia:
1. Myeloproliferative disorders.