Cells of the Immune System

A Quick Org Chart Quiz

Immunity
____?___Immunity
Specific
Uses ____?____ to
recognize and mark
specific amino acid
sequences in
foreign proteins
Slow but tidy
____?_____ Immunity
Non-Specific
Fast but sloppy
Bodys first response
Immunity
____?___Immunity
Specific
Uses ____?____ to
recognize and mark
specific amino acid
sequences in
foreign proteins
Slow but tidy
____?_____ Immunity
Non-Specific
Fast but sloppy
Bodys first response
_____?______
Chemicals (not cells!)
released from epithelial
cells that are infected
with a ____?____.

They interfere with
endocytosis,
exocytosis, and
_____?______ in
neighboring cells so as
to slow the spread
of the ____?_____.

A non-specific throttling back
of local metabolic activity.
Immunity
____?___Immunity
Specific
Uses ____?____ to
recognize and mark
specific amino acid
sequences in
foreign proteins
Slow but tidy
____?_____ Immunity
Non-Specific
Fast but sloppy
Bodys first response
____?_____ _____?______
Full of vesicles (grains!) of
_________?____________. These
cells hold infection at bay while we
mount a more specific response.

Three kinds:
1. _____?______ (kill bacteria)
1. Follow _____?______from
_______?______ to site of
infection
2. Roll along endothelial cells
using ______?_______
3. Extravasation
4. Activity at site of infection
causes _____?_____to
release _____?_____,
leading to inflammation
2. Eosinophils (kill worms)
3. Basophils
Chemicals (not cells!)
released from epithelial
cells that are infected
with a ____?____.

They interfere with
endocytosis,
exocytosis, and
_____?______ in
neighboring cells so as
to slow the spread
of the ____?_____.

A non-specific throttling back
of local metabolic activity.
Immunity
____?_____ _____?______
Full of vesicles (grains!) of
_________?____________. These
cells hold infection at bay while we
mount a more specific response.

Three kinds:
1. _____?______ (kill bacteria)
1. Follow _____?______from
_______?______ to site of
infection
2. Roll along endothelial cells
using ______?_______
3. Extravasation
4. Activity at site of infection
causes _____?_____to
release _____?_____,
leading to inflammation
2. Eosinophils (kill worms)
3. Basophils
Chemicals (not cells!)
released from epithelial
cells that are infected
with a ____?____.

They interfere with
endocytosis,
exocytosis, and
_____?______ in
neighboring cells so as
to slow the spread
of the ____?_____.

A non-specific throttling back
of local metabolic activity.
_______?_______:

Originate in _______?______ as
_______?_______
Span adaptive and innate immunity
Non-discriminative phagocytosis (at site
of infection, they eat any bacterial
matter they can find)
Act as antigen presenting cells using
______?_____ (they show bits of foreign
protein to adaptive immune system so it
can mount an effective response)

____?___Immunity
Specific
Uses ____?____ to
recognize and mark
specific amino acid
sequences in
foreign proteins
Slow but tidy
____?_____ Immunity
Non-Specific
Fast but sloppy
Bodys first response
Immunity
____?___Immunity
Specific
Uses ____?____ to
recognize and mark
specific amino acid
sequences in
foreign proteins
Slow but tidy
____?_____ Immunity
Non-Specific
Fast but sloppy
Bodys first response
____?_____ _____?______
Full of vesicles (grains!) of
_________?____________. These
cells hold infection at bay while we
mount a more specific response.

Three kinds:
1. _____?______ (kill bacteria)
1. Follow _____?______from
_______?______ to site of
infection
2. Roll along endothelial cells
using ______?_______
3. Extravasation
4. Activity at site of infection
causes _____?_____to
release _____?_____,
leading to inflammation
2. Eosinophils (kill worms)
3. Basophils
________?________
Two kinds with multiple subtypes each:

1. _______?________
1. T-Helper Cells: CD- _?_ and MHC
_?_ w/ antigen; trigger ___?___
maturation and division
2. T-Killer Cells: CD-_?_ and MHC
_?_ check for antigen; release
_____?____ to cause apoptosis
2. _________?________
1. _____?____ B-Cells: secrete
____?____
2. ____?_____ B-Cells: store
antibody in membrane
Chemicals (not cells!)
released from epithelial
cells that are infected
with a ____?____.

They interfere with
endocytosis,
exocytosis, and
_____?______ in
neighboring cells so as
to slow the spread
of the ____?_____.

A non-specific throttling back
of local metabolic activity.
Answers
Spoiler alert!
Immunity
Adaptive Immunity
Specific
Uses antibodies to
recognize and mark
specific amino acid
sequences in
foreign proteins
Slow but tidy
Innate Immunity
Non-Specific
Fast but sloppy
Bodys first response
Granulocytes Interferons
Full of vesicles (grains!) of
bleach, peroxides, and free radicals.
These cells hold infection at bay while
we mount a more specific response.

Three kinds:
1. Neutrophils (kill bacteria)
1. Follow chemoattractant
gradient from red bone
marrow to site of infection
2. Roll along endothelial cells
using selectins
3. Extravasation
4. Activity at site of infection
causes mast cells to
release histamine, leading
to inflammation
2. Eosinophils (kill worms)
3. Basophils
Lymphocytes
Two kinds with multiple subtypes each:

1. T-Lymphocytes
1. T-Helper Cells: CD-4 and MHC II
w/ antigen; trigger B cell
maturation and division
2. T-Killer Cells: CD-8 and MHC I
check for antigen; release
perforin to cause apoptosis
2. B-Lymphocytes
1. Plasma B-Cells: secrete
antibodies
2. Memory B-Cells: store antibody
in membrane
Chemicals (not cells!)
released from epithelial
cells that are infected
with a virus.

They interfere with
endocytosis,
exocytosis, and
protein synthesis in
neighboring cells so as
to slow the spread
of the virus.

A non-specific throttling back
of local metabolic activity.
Chemicals (not cells!)
released from epithelial
cells that are infected
with a virus.

They interfere with
endocytosis,
exocytosis, and
protein synthesis in
neighboring cells so as
to slow the spread
of the virus.
Immunity
Adaptive Immunity
Specific
Uses antibodies to
recognize and mark
specific amino acid
sequences in
foreign proteins
Slow but tidy
Innate Immunity
Non-Specific
Fast but sloppy
Bodys first response
Granulocytes Interferons
Full of vesicles (grains!) of
bleach, peroxides,
and free radicals.

Able to hold infection
At bay while we
mount a more
specific response.

Three kinds:
1. Neutrophils (kill bacteria)
2. Eosinophils (kill worms)
3. Basophils
Macrophages:

Originate in red bone marrow as
monocytes
Span adaptive and innate immunity
Non-discriminative phagocytosis (at site
of infection, they eat any bacterial
matter they can find)
Act as antigen presenting cells using
MHC Class II (they show bits of foreign
protein to adaptive immune system so it
can mount an effective response)