• A 25years old female presents with a painless

solitary lump in anterior neck.

• On examination, the lump moves with swallowing
and measures 3*3cm in size .
• Right sided cervical lymph nodes are palpable
• What is your provisional diagnosis?
Investigations
• Thyroid function tests
• Ultrasound
• Radionuclide scanning
• Fine needle aspiration cytology
Qiao's Pathology
Gross morphology

https://library.med.utah.edu/WebPath/ENDOHTML/ENDO063.html
Papillae formation
Ground glass or Orphan Annie
eye nuclei.
 Psammoma
bodies
https://library.med.utah.edu/WebPath/ENDOHTML/ENDO02html
Classification
• Papillary carcinoma (>85% of cases)
• Follicular carcinoma (5% to 15% of cases)
• Medullary carcinoma (5% of cases)
• Anaplastic (undifferentiated) carcinoma (<5% of
cases)
Bad prognostic factors

• Age older than 40 years

• The presence of extrathyroidal extension,

• Presence of distant metastases (stage)