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The cycle begins as enzymes strip the CoA portion from acetyl-
CoA. Only the two carbon acetyl part actually participates in the
Krebs Cycle.
The acetyl group then combines with a four-carbon compound
called Oxaloacetic Acid (already present in the mitochondrion), to
form a 6-carbon compound called Citric Acid.
The electrons are passed from one acceptor to the next down an
energy gradient until they reach the final electron acceptor, which
is oxygen.